Single cell suppression profiling of human regulatory T cells by Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wing

“…Traditionally their suppressive function has been assayed by mixing purified cell populations, which does not provide an accurate picture of a physiologically relevant response. …”
Get full text

The urgency of addressing zoonotic diseases surveillance: Potential opportunities considering One Health approaches and common European Data Spaces by Nicola Riccetti, Serena Signorelli, Angela Fanelli, Emanuele Massaro, Manlio Bacco, Wojciech Szewczyk, Dolores Ibarreta, Juan Carlos Ciscar, Alessandro Cescatti, Sandra Coecke, Ilaria Capua

“…An overarching layer, populated with data and generating integrative information, could support a One Health approach to research and policymaking for the preparedness and anticipation of zoonotic diseases. …”
Get full text

Artificial neural networks for stability analysis and simulation of delayed rabies spread models by Ramsha Shafqat, Ateq Alsaadi

“…Rabies remains a significant public health challenge, particularly in areas with substantial dog populations, necessitating a deeper understanding of its transmission dynamics for effective control strategies. …”
Get full text

Health Status and Health Determinants of Older Immigrant Women in Canada: A Scoping Review by Sepali Guruge, Birpreet Birpreet, Joan A. Samuels-Dennis

“…Increasing international migration in the context of aging populations makes a comprehensive understanding of older immigrant women’s health status and determinants of their health particularly urgent. …”
Get full text

Safety evaluation of changed use levels of the food enzyme triacylglycerol lipase from the non‐genetically modified Limtongozyma cylindracea strain AE‐LAYH (B) by EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Roos Anna deNijs, Magdalena Andryszkiewicz, Daniele Cavanna, Yi Liu

“…It was calculated to be up to 0.220 mg TOS/kg body weight (bw) per day in European populations. Based on the new data, the revised exposure estimation and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.…”
Get full text

In Vitro Investigation of Potential Anti-Diabetic Activity of the Corm Extract of Hypoxis Argentea Harv. Ex Baker by Akinrinde Akinleye, Koekemoer Trevor, Venter Maryna Van De, Bradley Graeme

“…Our results suggest that the acclaimed anti-diabetic effects of H. argentea could be mediated by its promotion of glucose utilization and preservation of pancreatic beta cell populations while preventing fat accumulation in adipocytes.…”
Get full text

A Rock Fracturing Method Using High-Pressure Gas Expansion: Case Study on Its Application in Hangzhou-Lin’an Intercity Railway by Dunwen Liu, Yu Tang, Caiwu Cai, Yinghua Jian

“…It is difficult to perform nonexplosive continuous excavation on hard rock connecting passage in crowded cities with dense high buildings and populations safely and rapidly. Therefore, a new method of rock fracturing through high-pressure gas expansion is proposed. …”
Get full text

Formulation of a Ready-to-Cook Soup Mix Using Microencapsulated Protein Hydrolysate Obtained from Pink Perch By-Product by Asha Kumari, Nutan Kaushik, Rasa Slizyte, Khushboo .

“…Therefore, RTC MPHS mix can be used as a nutrient-rich product in protein-deficient populations.…”
Get full text

Global evolution of research on autohydrolysis (hydrothermal) pretreatment as a green technology for biorefineries: A bibliometric analysis by Yuxin Yu, Wenhui Pei, Xiaoxue Zhao, Aldo Joao Cárdenas-Oscanoa, Caoxing Huang

“…Concurrently, the domain of hydrothermal pretreatment has progressively become more cross-disciplinary, intertwining with the sectors of microbial populations and genomes.…”
Get full text

Recovery of nearly 3,000 archaeal genomes from 152 terrestrial geothermal spring metagenomes by Yan-Ling Qi, Hao-Tian Zhang, Meng Li, Wen-Jun Li, Zheng-Shuang Hua

“…Abstract Terrestrial geothermal springs, reminiscent of early Earth conditions, host diverse and abundant populations of Archaea. In this study, we reconstructed 2,949 metagenome-assembled genomes (MAGs) from 152 metagenomes collected over six years from 48 geothermal springs in Tengchong, China. …”
Get full text

Modeling Spatial Social Complex Networks for Dynamical Processes by Shandeepa Wickramasinghe, Onyekachukwu Onyerikwu, Jie Sun, Daniel ben-Avraham

“…We develop a Spatial Social Complex Network (SSCN) model that captures not only essential connectivity features of real-life social networks, including a heavy-tailed degree distribution and high clustering, but also the spatial location of individuals, reproducing Zipf’s law for the distribution of city populations as well as other observed hallmarks. We then simulate Milgram’s Small-World experiment on our SSCN model, obtaining good qualitative agreement with the known results and shedding light on the role played by various network attributes and the strategies used by the players in the game. …”
Get full text

Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis by Ting Hu, Feiling Wang, Qiuchen Duan, Xueyang Zhao, Fen Yang

“…Abstract Fatigue is a common health complaint in older adults, but its prevalence varies widely among studies due to differences in populations and assessment tools. The objective of this review is to systematically evaluate the prevalence of fatigue and perceived fatigability in older adults with PRISMA 2020. …”
Get full text

Development of a Territorial Planning Model of Wind and Photovoltaic Energy Plants for Self-Consumption as a Low Carbon Strategy by Francisco Santana-Sarmiento, Sergio Velázquez-Medina

“…The case study involved locating areas close to populated settlements which are generally cut off from areas commonly marked out for large-scale wind and solar energy exploitation. …”
Get full text

Sedimentary Organic Matter and Phosphate along the Kapuas River (West Kalimantan, Indonesia) by Pei Sun Loh, Chen-Tung Arthur Chen, Gusti Z. Anshari, Jiann-Yuh Lou, Jough-Tai Wang, Shu-Lun Wang, Bing-Jye Wang

“…Sedimentary P levels were the highest along the densely populated areas downstream from the Kapuas River; the second highest along the midstream river, which is surrounded by oil palm plantations; and the lowest along the upper river, which is surrounded by forest. …”
Get full text

Growth and Survival of Acid-Resistant and Non-Acid-Resistant Shiga-Toxin-Producing Escherichia coli Strains during the Manufacture and Ripening of Camembert Cheese by M. P. Montet, E. Jamet, S. Ganet, M. Dizin, S. Miszczycha, L. Dunière, D. Thevenot, C. Vernozy-Rozand

“…The STEC counts (AR and NAR) initially increased by 1 to 2 log⁡10 CFU g−1 during cheese-making. Thereafter, the populations stabilized during salting/drying and then decreased during the early stages of ripening. …”
Get full text

Novel delivery systems for phages and lysins in the topical management of wound infections: a narrative review by Pan Yang, Jing Li, Xiumei Ma, Nan Hu, Zhangyong Song, Bin Chen, Shizhu Li

“…The findings highlighted the positive effects of the five novel delivery systems for phages and lysins in WI management, significantly reducing wound bacterial populations, and accelerating healing at the injury site. …”
Get full text

Impact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human Senescence by Mariacristina Amato, Alessandro Polizzi, Gaia Viglianisi, Francesco Leonforte, Marco Mascitti, Gaetano Isola

“…In this regard, over the local periodontal treatment, lifestyle modifications and adjunctive therapies may offer synergistic benefits in ameliorating both oral and systemic health in ageing populations. Elucidating the intricate connections between periodontitis and senescence is important for understanding oral health’s systemic implications for ageing and age-related diseases. …”
Get full text

Ecologic and Sociodemographic Risk Determinants for Dengue Transmission in Urban Areas in Thailand by Surachart Koyadun, Piyarat Butraporn, Pattamaporn Kittayapong

“…In the ecologic model, dengue risk was related to households situated in the ecotope of residential mixed with commercial and densely populated urban residential areas (RCDENPURA) (aOR = 2.23, ), high historical dengue risk area (aOR = 2.06, ), and presence of household window screens (aOR = 1.62, ). …”
Get full text

Direct‐Print 3D Electrodes for Large‐Scale, High‐Density, and Customizable Neural Interfaces by Pingyu Wang, Eric G. Wu, Hasan Uluşan, Eric Tianjiao Zhao, A.J. Phillips, Alexandra Kling, Madeline Rose Hays, Praful Krishna Vasireddy, Sasidhar Madugula, Ramandeep Vilkhu, Andreas Hierlemann, Guosong Hong, E.J. Chichilnisky, Nicholas A. Melosh

“…This approach enables customizable electrode shape, height, and positioning for precise targeting of neuron populations distributed in 3D. The effectiveness of this approach is demonstrated in tackling the critical challenge of interfacing with the retina—specifically, selectively targeting retinal ganglion cell (RGC) somas while avoiding the axon bundle layer. 6,600‐microelectrode, 35 µm pitch, tissue‐penetrating arrays are fabricated to obtain high‐fidelity, high‐resolution, and large‐scale retinal recording that reveals little axonal interference, a capability previously undemonstrated. …”
Get full text

Measuring Accessibility of Green Spaces for the Health and Wellbeing of Inhabitants of the Milan Metropolitan Area by Maria Chiara Pastore, Claudia Ida Maria Parenti, Corinna Patetta

“…This research identifies every UGS capable of contributing to people’s physical and mental wellbeing in the Milan metropolitan area (MMA), one of the most densely populated areas in Europe. The method allows for the various UGSs to be identified and classified using a comparative approach that considers both formal and informal green spaces through a qualitative territorial analysis and the support of open access databases (satellite and thematic maps). …”
Get full text