Effects of Metformin Added to Insulin in Adolescents with Type 1 Diabetes: An Exploratory Crossover Randomized Trial by Daizhi Yang, Jinhua Yan, Hongrong Deng, Xubin Yang, Sihui Luo, Xueying Zheng, Jing Lv, Wen Liang, Mengjie Hong, Zekai Wu, Bin Yao, Jianping Weng, Wen Xu

“…However, metformin added to insulin significantly increased heart rate variability, suggesting that metformin might improve cardiovascular autonomic function in this population.…”
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Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179 by Yuchen Li, Chaemin Lim, Taylor Dismuke, Daniel S. Malawsky, Sho Oasa, Zara C. Bruce, Carolin Offenhäuser, Ulrich Baumgartner, Rochelle C. J. D’Souza, Stacey L. Edwards, Juliet D. French, Lucy S. H. Ock, Sneha Nair, Haran Sivakumaran, Lachlan Harris, Andrey P. Tikunov, Duhyeong Hwang, Coral Del Mar Alicea Pauneto, Mellissa Maybury, Timothy Hassall, Brandon Wainwright, Santosh Kesari, Gregory Stein, Michael Piper, Terrance G. Johns, Marina Sokolsky-Papkov, Lars Terenius, Vladana Vukojević, Leon F. McSwain, Timothy R. Gershon, Bryan W. Day

“…Abstract OLIG2-expressing tumor stem cells have been shown to drive recurrence in Sonic Hedgehog (SHH)-subgroup medulloblastoma (MB) and patients urgently need specific therapies to target this tumor cell population. Here, we investigate the therapeutic potential of the brain-penetrant orally bioavailable, OLIG2 inhibitor CT-179, using SHH-MB explant organoids, PDX and GEM SHH-MB models. …”
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Gambaran Kadar Gula Darah pada Mahasiswa Fakultas Kedokteran Universitas Andalas yang Memiliki Berat Badan Berlebih dan Obesitas by Putri Auliya, Fadil Oenzil, Zelly Dia Dia Rofinda

“…Samples from this study is the total sampling population of 25 people</em><em>. The variables were</em><em> fasting blood sugar, glucose tolerance, BMI and Physical Activity. …”
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Dynamic development of gut microbiota and metabolism during and after weaning of kittens by Hong Zhang, Yang Ren, Siyu Wei, Hongli Jin, Yizhen Wang, Mingliang Jin

“…Abstract Background As the pet population grows, there is increasing attention on the health and well-being of companion animals. …”
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Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis by Ningning Yue, Hailan Zhao, Peng Hu, Yuan Zhang, Chengmei Tian, Chen Kong, Zhiliang Mai, Longbin Huang, Qianjun Luo, Daoru Wei, Ruiyue Shi, Shaohui Tang, Yuqiang Nie, Yujie Liang, Jun Yao, Lisheng Wang, Defeng Li

“…Third, L. reuteri-CMVs increased the population of double positive (DP) CD4+CD8+ T cells in the intestinal epithelial layer, suppressing gut inflammation and maintaining gut mucosal homeostasis. …”
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A comparison of applicant and accepted student characteristics to research training programs with implications for recruitment and selection strategy by Young-Hee Cho, Young-Hee Cho, Chi-Ah Chun, Chi-Ah Chun, Hector Ramos, Paul Buonora, Paul Buonora, Paul Buonora, Vasanthy Narayanaswami, Vasanthy Narayanaswami, Kim-Phuong L. Vu, Kim-Phuong L. Vu

“…These findings imply that research training programs can effectively recruit diverse students from underrepresented populations in STEM by using intentional outreach and recruitment efforts coupled with an objective and holistic selection process.…”
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The impact of attitude towards an e-tax system on tax compliance of Vietnamese enterprises: Adoption of an e-tax system as a mediator by Ha Thi Hai Do, Yen Thi Hai Mac, Hoa Thi Van Tran, Thuy Thi Le Nguyen

“…The findings of the study suggest some policy implications for improving tax compliance in Vietnam including (1) continuously improving the information technology infrastructure for both tax authorities and enterprises; (2) widely disseminating tax law and providing support services to enterprises; (3) upgrading the e-tax system to ensure the effective coordination between tax authorities, tax officials, enterprises, and other authorities in applying e-tax; (4) consolidating the supervision and assessment of the adoption of e-tax; (5) promoting information and education on the perception of complying with the tax law for taxpayers in particular and the entire population in general; (6) developing a tax administration strategy based on tax compliance.…”
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Correlates of and changes in aerobic physical activity and strength training before and after the onset of COVID-19 pandemic in the UK: findings from the HEBECO study by Lion Shahab, Abigail Fisher, Phillippa Lally, Aleksandra Herbeć, Dimitra Kale, Verena Schneider

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Distinct Neutralising and Complement-Fixing Antibody Responses Can Be Induced to the Same Antigen in Haemodialysis Patients After Immunisation with Different Vaccine Platforms by Nadezhda Wall, Rachel Lamerton, Fiona Ashford, Marisol Perez-Toledo, Aleksandra Jasiulewicz, Gemma D. Banham, Maddy L. Newby, Sian E. Faustini, Alex G. Richter, Haresh Selvaskandan, Roseanne E. Billany, Sherna F. Adenwalla, Ian R. Henderson, Max Crispin, Matthew Graham-Brown, Lorraine Harper, Adam F. Cunningham

“…Encouragingly, exploiting immunological memory by using mRNA vaccines and boosting may improve the success of vaccination strategies in this vulnerable patient population.…”
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Venous thromboembolism incidence and risk factors associated with immune checkpoint inhibitors among patients with advanced non-small cell lung cancer by Chi Nguyen, Alok A Khorana, John Barron, Jennell Palaia, Lisa Rosenblatt, Radhika Pisupati, Ning Huang, Kerrin Gallagher, T Christopher Bond

“…VTE is a common complication of lung cancer, and there is a continued need for awareness of VTE as a comorbidity in this population.…”
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Study protocol on risk factors for the diagnosis of gestational diabetes mellitus in different trimesters and their relation to maternal and neonatal outcomes (GDM-RIDMAN) by Khalida Ismail, Boon How Chew, Iliatha Papachristou Nadal, Angus Forbes, Nurul Iftida Basri, Rozita Zakaria, Pamela Phui Har Yap, Veronika Rysinova, Intan Nureslyna Samsudin, Nurain Mohd Noor, Ziti Akthar Supian, Haslinda Hassan, Fuziah Paimin, Siti Rohani Mohamed Alias, Norizzati Bukhary Ismail Bukhary, Madeleine Benton

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Profil Penderita Penyakit Tuberkulosis Paru BTA Positif yang Ditemukan di BP4 Lubuk Alung periode Januari 2012 – Desember 2012 by Eni Yulvia Susilayanti, Irvan Medison, Erkadius .

“…Using the enterety of the population. The results of this study indicate that in this period the number of people who went to BP4 Lubuk Alung were 19.440 people, 3.224 of them suspected tuberculosis. …”
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Development of a Comprehensive Fall Risk Assessment Tool for Older People in Elderly Care Institutions and Its Test by LUO Yuan, ZHANG Hua, WANG Sanxiang, ZHANG Mengxi, DENG Yuqian, RAN Haiye, LIU Jiaxin, ZHANG Yi, CHEN Xi, WU Yibo, ZHAO Liping

“…Background Since China officially entered into an aging society in 1999, the issue of population aging has escalated significantly, leading to institutional care becoming a popular option for older people. …”
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Life history, reproductive, and demographic parameters for bottlenose dolphins (Tursiops truncatus) in Sarasota Bay, Florida by Randall S. Wells, Aleta A. Hohn, Michael D. Scott, Jay C. Sweeney, Forrest I. Townsend, Jason B. Allen, Aaron A. Barleycorn, Katherine A. McHugh, Kim Bassos-Hull, Gretchen N. Lovewell, Deborah A. Duffield, Cynthia R. Smith, A. Blair Irvine

“…Periods of increased loss rates were related to environmental events, and factors that may be important to long-term population resilience were suggested.…”
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The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review by Perez, Grégoire, Bournez, Laure, Boulanger, Nathalie, Fite, Johanna, Livoreil, Barbara, McCoy, Karen D., Quillery, Elsa, René-Martellet, Magalie, Bonnet, Sarah I.

“…The diversity of vertebrate host species used by this tick, along with their degree of infestation when available, are presented and discussed with respect to their potential contribution to the population dynamics of I. ricinus and the circulation of tick-borne zoonotic pathogens. …”
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Knowledge, Attitude, and Barriers Influencing Seasonal Influenza Vaccination Uptake by Mazin A. Barry, Khalid I. Aljammaz, Abdulaziz A. Alrashed

“…We concluded that there is a low influenza vaccine uptake rate among our study population, considering that the barriers most commonly chosen by participants are solvable with health education and campaigns oriented towards delivering facts about the vaccine and dispelling misinformation; such measures are highly recommended and are postulated to carry a great benefit that should target common misconceptions identified in this study.…”
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Feasibility and Acceptability of Antenatal Hepatitis C Screening: A Pilot Study by Joseph Valamparampil, Jaswant Sira, Maxine Brown, Saket Singhal, Deirdre Kelly

“…The median age of the study population was 29 years (range, 18–46). Knowledge about blood-borne viruses was limited; 75% of women had some understanding about antenatal hepatitis B (HBV) and human immunodeficiency virus (HIV) testing. …”
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Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“… Abstract BackgroundMental illness affects an estimated 25% of the global population, with treatment gaps persisting worldwide. …”
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Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders by David Mataix-Cols, Christian Rück, Lorena Fernández de la Cruz, Kayoko Isomura, Henrik Larsson, Paul Lichtenstein, Brian M D’Onofrio, Anna Sidorchuk, Zheng Chang, James J Crowley, Ralf Kuja-Halkola, Isabell Brikell, Josep Pol-Fuster, Anna Holmberg, Lina Martinsson

“…Whether this association is driven by familial factors is unknown. This population-based family study explored the familial co-aggregation of OCD and cardiometabolic disorders.Methods We identified 6 049 717 individuals born in Sweden between 1950 and 2008, including 50 212 individuals with OCD, and followed them up to 2020. …”
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Assessing and Enhancing Nutrition and Physical Activity Environments in Early Childhood Education and Care Centers: Scoping Review of eHealth Tools by Joyce Hayek, Kelsi Dickson, Lynne M Z Lafave

“…Eligibility criteria were (1) early childhood educators (population); (2) eHealth (digital) technologies, such as websites, smartphone apps, emails, and social media; and (3) tools designed to assess or deliver interventions aimed at improving best practices for nutrition, physical activity, or both within ECEC settings (context). …”
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