Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

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Post-therapeutic support and rehabilitation for breast cancer women in complete remission in a thermal resort: study protocol for the PACThe Real-Life conditions observational tria... by Mélanie Godiveau, Judith Passildas, Emilie Thivat, Mélanie Casile, Céleste Pinard, Alexia Giro, Marie-Ange Mouret-Reynier, Ioana Molnar, Catherine Abrial, Claude-Eugène Bouvier, Yves-Jean Bignon, Xavier Durando

“…The comprehensive overview of the program PACThe will likely contribute to enhancing thermal therapy post-cancer rehabilitation in this population in real life conditions. Trial registration The PACThe Real-Life conditions trial is a prospective observational study registered at the ANSM registry (2022-A00171-42) on March 1, 2022. …”
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Fermi Unassociated Sources in the MeerKAT Absorption Line Survey by Morgan Himes, Preshanth Jagannathan, Dale A. Frail, Frank Schinzel, Neeraj Gupta, S. A. Balashev, F. Combes, P. P. Deka, H.-R. Klöckner, E. Momjian, J. D. Wagenveld

“…We show that MALS, due to its excellent continuum sensitivity, can detect 80% of the known pulsar population. This exhibits the promise of identifying exotic pulsar candidates with future image-based surveys with the Square Kilometre Array and its precursors.…”
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TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC by Xiao-Mei Tang, Min-Min Shi, Jia-Cheng Wang, Yi-Jin Gu, Yu-Ting Dai, Qin-Xin Yang, Jia Liu, Ling-Jie Ren, Xin-Yun Liu, Chun Yang, Fang-Fang Ma, Ji-Bing Liu, Hong Yu, Da Fu, Yun-Feng Wang

“…This study highlights the clinical significance of TOPBP1 in the treatment of PDAC and emphasizes the potential implications for a broader population of patients.…”
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Genomic strategies to facilitate breeding for increased β-Glucan content in oat (Avena sativa L.) by Sumandeep Kaur Bazzer, Guilherme Oliveira, Jason D. Fiedler, Raja Sekhar Nandety, Jean-Luc Jannink, Melanie Caffe

“…However, the use of multi-environment data in the training population resulted in an increase in prediction accuracy (0.61–0.72) as compared to single-year (0.28–0.48) data. …”
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Analisis dan Evaluasi Pengalaman Pengguna PaTik Bali dengan Metode User Experience Questionnaire (UEQ) by I Nyoman Saputra Wahyu Wijaya, Putu Praba Santika, Ida Bagus Ary Indra Iswara, I Nyoman Alit Arsana

“…The evaluation was carried out on a population of 34 data. The User Experience Questionnaire (UEQ) evaluation has a good rating. …”
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Differential management and associations of dyslipidaemia and hypertension by glycaemic status in urban South Africans by N Peer, L Kotzé-Hörstmann, J Hill, A-P Kengne

“…Methods. This urban population-based cross-sectional study comprised participants with KD, NDD and normoglycaemia. …”
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HUBUNGAN KADAR KOLESTEROL DENGAN TEKANAN DARAH PENDERITA HIPERTENSI DI DUSUN SIDOMULYO DESA REJOAGUNG KECAMATAN PLOSO KABUPATEN JOMBANG The Correlation of Cholesterol levels with... by HENI MARYATI

“…Correlation descriptive research, with cross sectional approach. The population is all patients with hypertension in Sidomulyo Rejoagung Village District of Ploso Jombang of the total sampling method, a number of 34 people. …”
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Does completion of radical hysterectomy improve oncological outcomes of women with clinical early-stage cervical cancer and intraoperative detection of nodal involvement?: protocol... by Hui Xu, Qing Liu, Yu Xu, Yi Du, Ai Zheng, Cui Hu, Ya Jia, Qianwen Zhang, Yue-Dong He, Shuang-Shuang Cui, Yong Tian, Lin Ran, Fengmei Ke

“…This paper presents the protocol of a systematic review and meta-analysis regarding the management of this specific population of patients. This proposed study aims to answer the question: does completion of radical hysterectomy improve the oncological outcomes of women with clinical early-stage cervical cancer and intraoperatively detected nodal involvement?…”
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Improving the diagnostic accuracy of referrals for papilloedema (DIPP) study: protocol for a mixed-methods study by Luke Bennetto, Beth Stuart, Jonathan Benger, Matthew J Ridd, Helen Bolton, William Hollingworth, Michael Bowen, Amar Shah, Samuel William David Merriel, Alyson Huntley, Victoria Wilson, Maria Theresa Redaniel, Paul Roy, Denize Atan, Frank Moore, Olivia Skrobot, Mary-Ann Sherratt, Marcia Lucraft, Christina Stokes

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Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam by Huan Vinh Dong, Paul Adamson, Dieu Hoa Pham, Quynh Hoa Pham, Hai Ha Long Le, Loc Quang Pham, Hao Thi Minh Bui, Giang Minh Le, Jeffrey D. Klausner

“…Commensal Neisseria species in the oropharynx are an important reservoir of AMR genes that are transferred to N. gonorrhoeae, yet few data about AMR among commensal Neisseria in populations at risk for AMR exist. Methods: From May 2022 to December 2023, men in an HIV pre-exposure prophylaxis program in Hanoi, Vietnam, were recruited for this study. …”
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High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis by Sehhoon Park, Jaeyun Jung, You Jeong Heo

“…In contrast, exhausted T-cell and M2 macrophage counts were increased in the non-responder group.Conclusions The overall incidence of TMB status was analyzed by the TSO500 assay, and TMB-H was observed in 14.7% of the pan-cancer population. In a real-world setting, TMB-H identified by a target sequencing panel seemed to predict response to anti-PD-(L)1 therapy, especially in patients with a higher proportion of immune cells enriched in the tumor region.…”
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Endogenous sex hormone levels are associated with the revised Framingham Stroke Risk Profile in postmenopausal women: a longitudinal study in a Swedish cohort by Kristin Ottarsdottir, Åsa Tivesten, Claes Ohlsson, Ying Li, Margareta Hellgren, Ulf Lindblad, Bledar Daka

“…Methods This is an observational cross-sectional study on the Vara-Skövde cohort, a Swedish population-based study for longitudinal surveillance of the development and progress of type 2 diabetes and hypertension. …”
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Cryptic transmission of a SARS-CoV-2 variant detected by wastewater surveillance in Panama by Melissa Gaitán, Yamitzel Zaldivar, Michelle Hernandez, Jessica Góndola, Oris Chavarría, Brechla Moreno, Danilo Franco, Rodrigo DeAntonio, Santiago Mirazo, Florencia Cancela, Maria Eugenia Barnett, Alexander A. Martinez, Juan Miguel Pascale, Sandra López-Vergès

“…Given the significance of asymptomatic cases in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, cases often undetected by the ILI surveillance, a more comprehensive approach was essential to track the circulation of SARS-CoV-2 variants in the population. In response, many countries swiftly adopted wastewater surveillance, which allowed the early detection of SARS-CoV-2 variants before they were identified through molecular characterization from confirmed clinical cases. …”
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Potential 2050 distributions of World Terrestrial Ecosystems from projections of changes in World Climate Regions and Global Land Cover by Roger Sayre, Charlie Frye, Sean Breyer, Patrick R. Roehrdanz, Paul R. Elsen, Kevin Butler, Clint Brown, Jill Cress, Deniz Karagulle, Madeline Martin, Florencia Sangermano, Regan L. Smyth, Terry L. Sohl, Nicholas H. Wolff, Dawn J. Wright, Zhouting Wu

“…These changes occur in areas where 31 %, 36 %, and 41 % of the global population lives. Projected changes in ecosystem distributions related to temperature change are approximately an order of magnitude greater than for aridity change. …”
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Symptoms of anxiety and depression among health and social science students: A multicenter study by Lara Guedes Pinho, Maria Engström, Brooke C. Schneider, Cesar Fonseca, Magnus Lindberg, Johanna Schröder, Anabela Afonso, Lena Jelinek, Johanna Börsting, Gonçalo Jacinto, Annika Nilsson

“…Addressing these factors could play a crucial role in improving mental health outcomes in this population.…”
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An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of Bordetella pertussis by Alexandre D’Halluin, Denisa Petráčková, Ivana Čurnová, Jakub Držmíšek, Jan Čapek, Peggy Bouquet, Loïc Henin, Rudy Antoine, Loïc Coutte, Camille Locht, Branislav Večerek, David Hot

“…In Bordetella pertussis, the causative agent of whooping cough, the numerous IS elements induce genomic rearrangements and contribute to the diversity of the global B. pertussis population. Previously, we have shown that the majority of IS-specific endogenous promoters induce the synthesis of alternative transcripts and thereby affect the transcriptional landscape of B. pertussis. …”
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Energy and cost analysis of bottom waste cooking oil (B-WCO) based solid alcohol biofuel and supernatant waste cooking oil (S-WCO) based biodiesel by Ramin Nabizadeh, I.L. García, Zohreh Bahmani, Abbas Norouzian Baghani, Sodeh Sadjadi, Kamyar Yaghmaeian, Bahram Kamarehie, Amir Hossein Mahvi, Masud Yunesian

“…Hence, considering the energy balances of the valorization process for WCO, the population growth in cities, and the need for inexpensive and plentiful sources of renewable energy, the production of SABF and biodiesel may offer a valuable solution in developing countries.…”
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Provincial distribution and predictors of desire for more children among married and cohabiting women in Sierra Leone by Augustus Osborne

“…This high fertility rate impacts population growth, straining resources like healthcare and education. …”
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Mathematical modeling in autoimmune diseases: from theory to clinical application by Yaroslav Ugolkov, Yaroslav Ugolkov, Yaroslav Ugolkov, Antonina Nikitich, Antonina Nikitich, Cristina Leon, Gabriel Helmlinger, Kirill Peskov, Kirill Peskov, Kirill Peskov, Kirill Peskov, Victor Sokolov, Victor Sokolov, Alina Volkova, Alina Volkova

“…The number of targeted therapies available on the market is limited, whereas the prevalence of autoimmune conditions in the global population continues to rise. Mathematical modeling of biological systems is an essential tool which may be applied in support of decision-making across R&D drug programs to improve the probability of success in the development of novel medicines. …”
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