Factors influencing healthcare workers’ perceived compliance with infection prevention and control standards, North Bank East region, The Gambia, a cross-sectional study by Sheriffo M.K. Darboe, Sandra A. Darfour-Oduro, Godsway Edem Kpene, Abou Kebbeh, Nuha Fofana, Manjally Ndow, Kawsu Sanyang, Dwomoh Duah, Alfred Edwin Yawson, Ernest Kenu, Harriet Affran Bonful

“…The sample size was calculated using the Cochrane formula, based on a healthcare worker population of 408, with a 95% confidence interval. Adjustments were made for a 10% non-response rate and a compliance level of 50%. …”
Get full text

COVID-19 Mortality in Children: A Referral Center Experience from Iran (Mofid Children’s Hospital, Tehran, Iran) by Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaiee, Noushin Marhamati, Seyyedeh Narjes Ahmadizadeh, Azita Behzad, Seyedeh Masumeh Hashemi, Saeed Sadr, Maryam Rajabnejad, Mahnaz Jamee, Abdollah Karimi

“…The knowledge regarding the mortality rate and risk factors of COVID-19 among the pediatric population is lacking. In this regard, we aimed to report the clinical and laboratory characteristics of deceased pediatric patients with SARS-CoV-2 infection. …”
Get full text

Inflammatory biomarkers of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in 563 severe OSA patients before and after surgery by Chung-Wei Lin, Pei-Wen Lin, Li-Wen Chiu, Han-Tan Chai, Chun-Tuan Chang, Michael Friedman, Anna M. Salapatas, Sara Rahavi-Ezabadi, Hsin-Ching Lin

“…Results After OSA surgery, the major PSG estimates, NLR and PLR dropped significantly in the overall population. In those with a higher preoperative NLR (pre-operative NLR≧3) and PLR (pre-operative PLR≧150), the mean (SD) difference of NLR (− 0.8 [1.6], 95% CI − 1.5 to − 0.2) and PLR (− 41.6 [40], 95% CI − 52.8 to − 30.5) were even more substantial. …”
Get full text

THE PLACE OF PROFESSIONAL EDUCATION SYSTEM IN FORMATION OF GRADUATES’ COMPETITIVENESS by G. F. Shafranov-Kutsev, G. Z. Efimova

“…Scientific interest is the formation of youth competitiveness as the special social and demographic group having a strategic importance for the country. In the course of population competitiveness formation, the leading place is taken by an education system and professional education.The aim of the present publication was to scientifically judge modern professional education system aspects directed to formation of a competitive orientation and competitiveness of the younger generation. …”
Get full text

Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

“…Ketamine’s antidepressant effects and its impact on functional networks in non-resistant forms of major depressive disorder are expected to provide valuable insight into ketamine’s mechanism of action related to depression.MethodsThis study employs an existing network model of major depressive disorder to investigate the effects of ketamine on resting state connectivity in a therapy-non-resistant major depressive disorder population. In a randomized, double-blind, placebo-controlled, cross-over study, 0.5 mg/kg racemic ketamine or 0.9%NaCl was administered intravenously in 16 MDD patients. …”
Get full text

Comparative Study of Remimazolam and Midazolam During Sedated Upper Gastrointestinal Endoscopy: A Propensity Score Matching Analysis by Ryoji Ichijima, Hisatomo Ikehara, Tomomi Sugita, Daisuke Yamaguchi, Yasuhiko Nagata, Kanako Ogura, Mitsuru Esaki, Yosuke Minoda, Hiroyuki Ono, Yuki Maeda, Shinsuke Kiriyama, Tetsuya Sumiyoshi, Yuichi Kanmura

“…Overall, 36 participants from the clinical trial population who underwent upper gastrointestinal endoscopy using remimazolam and 199 patients who underwent the procedure with midazolam during the same period were included in this study. …”
Get full text

Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products by Maihöfner C, Mallick-Searle T, Vollert J, Kalita P, Sood Sethi V

“…However, while this type of study is effective for identifying use patterns and attitudes in the general population, recall bias limits the ability to collect safety and effectiveness data. …”
Get full text

A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ali Hussain Ansari, Saqib Hussain Ansari, Mubarak Jabeen Salman, Muhammad Usman Hussain Ansari, Rawshan Jabeen

“…Due to the need of chronic blood transfusions, transfusion-transmitted infection (TTI) incidence within this patient population is high. These largely include hepatitis C, hepatitis B, and the Human immunodeficiency virus (HIV). …”
Get full text

Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…Aetiologic distributions for each symptom were largely the same across regions and population strata, despite HIV status and age being significantly associated with several infection diagnoses. …”
Get full text

Call for Papers: Intergenerational Justice Prize 2020 by FRFG, IF (Foundation for the Rights of Future Generations, Intergenerational Foundation)

“…What percentage of the population is liable to these taxes? How are business assets handled? …”
Get full text

Randomized, Open-Label Phase 2 Study of Apalutamide plus Androgen Deprivation Therapy versus Apalutamide Monotherapy versus Androgen Deprivation Monotherapy in Patients with Bioche... by Rahul Aggarwal, Joshi J. Alumkal, Russell Z. Szmulewitz, Celestia S. Higano, Alan H. Bryce, Angela Lopez-Gitlitz, Sharon A. McCarthy, Branko Miladinovic, Kelly McQuarrie, Shibu Thomas, Ke Zhang, Eric J. Small

“…Of the few biomarkers expressed in blood, EPHA3 was significantly associated with shorter time to PSA progression (P=0.02) in the overall population. Conclusions. HRQoL was similar in patients treated with apalutamide alone, ADT alone, or their combination, although apalutamide plus ADT did not demonstrate statistically significant noninferiority in change from baseline in overall HRQoL. …”
Get full text

Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…Introduction Atrial fibrillation (AF) affects approximately 2.5% of the UK population, with a risk of 1 in 3–5 individuals after the age of 45 years. …”
Get full text

Microsatellite instability and somatic gene variant profile in solid organ tumors by Ibrahim Halil Erdogdu, Seda Orenay-Boyacioglu, Olcay Boyacioglu, Nesibe Kahraman-Cetin, Habibe Guler, Merve Turan, Ibrahim Meteoglu

“…Conclusions Our study covers not only colorectal cancer patients but also other solid tumor types, providing the first data from the Turkish population on the MSI-H/dMMR status and somatic mutation profile in the presence of this condition.…”
Get full text

International expert consensus on micronutrient supplement use during the early life course by Irene Cetin, Roland Devlieger, Erika Isolauri, Rima Obeid, Francesca Parisi, Stefan Pilz, Lenie van Rossem, Maternal Nutrition Delphi Study Group, Régine Steegers-Theunissen

“…Panellists reached consensus on the importance of diet and dietary supplement use during pregnancy and agreed on the lack of clarity and consistency in current guidelines, and the need for education in these areas for HCPs, pregnant people and the general population. For general low-risk populations, there was consensus on the importance of supplement use with iron and vitamin D from preconception through lactation, with folic acid and iodine from preconception through the second and third trimesters, respectively, with DHA from the first trimester through lactation and with calcium during lactation. …”
Get full text

Changes in sexual activities and risky sexual behaviors during the COVID-19 pandemic: A systematic review by Alinaghi Seyed Seyed Ahmad, Karimi Amirali, Mirzapour Pegah, Qaderi Kowsar, Mohammadi Parsa, Salehi Mohammad Amin, Tantuoyir Marcarious M., Arjmand Ghazal, Shahmohamadi Elnaz, Mahalleh Mehrdad, Kianzad Shaghayegh, Pashaei Ava, Khodaei Sepideh, Afsahi Amir Masoud, Mehraeen Esmaeil

“…Considering different groups of the population concerning their sexual behaviors is a necessary step in approaching healthy sexual behavior strategies, through which the adverse effects of a pandemic are minimized.…”
Get full text

Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…Abstract Background Each breast cancer (BC) risk factor has different effects on different populations. However, there are no well-studied and validated BC risk prediction models for Japanese women. …”
Get full text

School performance gap between non-immigrant and second-generation immigrant children in Sweden—time trends and contributing factors by Kenta Okuyama, Sara Larsson Lönn, Ardavan M. Khoshnood, Ardavan M. Khoshnood, Shervin Assari, Shervin Assari, Shervin Assari, Shervin Assari, Jan Sundquist, Jan Sundquist, Kristina Sundquist, Kristina Sundquist

“…We used multiple Swedish population registers, including 829,787 children born 1994–2004. …”
Get full text

Improving health outcomes and quality at the subdistrict level: Evaluation of the ‘3 feet model’ in Waterberg District, Limpopo Province, South Africa by H Schneider, F Mukinda, J Cupido, J Wessels, P Kupa, P Leboho, N Nkoana, N Bosch, Y Pillay

“…While not advocating for a cut-and-paste approach to improving quality and outcomes, positive experiences in Waterberg District suggest that the principles and mechanisms of action of the 3 feet model have wider relevance for policy and practice, especially as emphasis shifts towards the subdistrict as a core unit of population health and wellbeing in SA. …”
Get full text

Age- and sex-adjusted CT-based reference values for temporal muscle thickness, cross-sectional area and radiodensity by Emilia K. Pesonen, Otso Arponen, Jaakko Niinimäki, Nicole Hernández, Lasse Pikkarainen, Sami Tetri, Tommi K. Korhonen

“…Subjects diagnosed with a concussion at the Oulu University Hospital between January 2014 and December 2022 (n = 9254) were identified to obtain a reference population. Subjects with significant pre-existing co-morbidities were excluded. …”
Get full text

High-starchy carbohydrate diet aggravates NAFLD by increasing fatty acids influx mediated by NOX2 by Yuqi Gao, Rui Hua, Kezheng Peng, Yuemiao Yin, Chenye Zeng, Yannan Guo, Yida Wang, Liyuan Li, Xue Li, Ying Qiu, Zhao Wang

“…Nonalcoholic fatty liver disease (NAFLD) is a high-incidence lipid disorder that affects more than a quarter of the population worldwide, and dietary intervention is the recognized treatment. …”
Get full text