Novel PITX2 Mutations including a Mutation Causing an Unusual Ophthalmic Phenotype of Axenfeld-Rieger Syndrome by Liqin Huang, Yong Meng, Xiangming Guo

“…The PITX2 gene may be responsible for a significant portion of ARS with additional systemic defects in the Chinese population. This is the first reported case of a mutation at the 3′ end of the PITX2-coding region extending the phenotypic consequences to bilateral aniridia. …”
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The Experience of Survivors of Firearm Suicide Attempts: A Retrospective Case Series by Jeffrey R. Savarino, MD, MPH, Emily Rubin, MD, JD, Peter T. Masiakos, MD, MS, Rachel McLellan, BA, Myron L. Rolle, MD, MSc, Pranav Nanda, MD, Christopher J. Stapleton, MD, Chana A. Sacks, MD, MPH

“…These data offer an ability to learn from the experience of survivors of firearm suicide attempts, a rare population.…”
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Prevalence of Malaria among Adults in Ethiopia: A Systematic Review and Meta-Analysis by Fasil Adugna Kendie, Tamirat Hailegebriel W/kiros, Endalkachew Nibret Semegn, Melaku Wale Ferede

“…The current systematic review and meta-analysis showed that the pooled prevalence of malaria among adults was found to be greater than the general population and nearly equal to pregnant women. Therefore, the current prevention and control measures, which are related to both vectors and parasites, should be strengthened.…”
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ESTIMATION OF THE FIRST MATURITY SIZE OF SILVER BARB (Barbonymus gonionotus) IN SIDENRENG LAKE, SOUTH SULAWESI by Hasrianti Hasrianti, Gondo Puspito, Budhi Hascaryo Iskandar, Mohammad Imron, Wazir Mawardi

“…These activities have led to a decline in the fish population in the Lake. Therefore, information related to the fisheries biology of the fish is crucial. …”
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Knowledge, attitudes, and practices (KAP) of animal health staff and farmers towards brucellosis control in sheep and goat in China: A cross-sectional study. by Quangang Xu, Alongkorn Amonsin, Saharuetai Jeamsripong

“…<h4>Background</h4>In China, brucellosis has resurfaced recently with a discernible spatial distribution, particularly affecting dairy herds and small ruminant populations. However, limited dissemination of knowledge, attitudes, and practices (KAP) for brucellosis control exists among farmers and animal health staff. …”
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Global, regional, and national burdens of low back pain in women of childbearing age from 1990 to 2021: an analysis based on the global burden of disease study 2021 by Shiwen Zhang, Xuan Ma, Yao Yao, Huashan Pan, Lijuan Zou

“…In age patterns, the highest prevalence and YLDs rates of LBP were found among women in the 45–49 age group(the prevalence: 14,412.77 per 100,000 in 2021 [95% UI: 10,482.27 to 19,077.3]) (the YLDs: 1,639.56 per 100,000 population (95% UI: 1,035.24 to 2,494.9]). Conclusion Despite declines in the prevalence and YLDs of WCBA LBP, the burden remains high. …”
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miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure by Yuran Wang, Zeming Wang, Han Hao, Yuwei Zhao, Jian Wang, Weixuan Wang

“…Moreover, healthcare for the hypertensive population with environmental or occupational pollutants has become an issue of increasing concern in public health. …”
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Impact of Kefir Derived Lactobacillus kefiri on the Mucosal Immune Response and Gut Microbiota by P. Carasi, S. M. Racedo, C. Jacquot, D. E. Romanin, M. A. Serradell, M. C. Urdaci

“…Quantitative PCR analysis of different bacterial groups revealed only significant changes in Lactobacillus population. In conclusion, L. kefiri is a good candidate to be used in gut inflammatory disorders.…”
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Significant room for improvement in the prehospital assessment and treatment of acute abdominal pain: a retrospective observational study by Rasmus Bjerén, Carl Magnusson, Johan Herlitz, Denise Bäckström

“…Methods A retrospective cohort study of pain management in EMS patients with AAP in a central Swedish region. The region had a population density of 15.7 inhabitants per square kilometer spread over a mix of small urban and rural settings. …”
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The Protective Effects of 18β-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling by Haiming Chen, Huazhen Liu, Bin Tang, Yuchao Chen, Ling Han, Jingjie Yu, Yuhong Yan, Chuanjian Lu

“…Psoriasis is recognized as an autoimmune and inflammatory dermatosis, which is estimated to affect 2-3% of the population worldwide. 18β-Glycyrrhetinic acid (GA), one of the main ingredients of Licorice (Glycyrrhiza glabra L.), has been shown to have numerous pharmacological effects such as antioxidative, antitumor, and anti-inflammatory activities. …”
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Advancing Food Security with Farmed Edible Insects: Economic, Social, and Environmental Aspects by José E. Aguilar-Toalá, Abraham M. Vidal-Limón, Andrea M. Liceaga

“…Thus, edible insects can address the future global protein demand of an ever-increasing world population. In this context, several aspects related to their sustainability have been explored and addressed from an environmental perspective. …”
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Facilitators and barriers of alcohol goals for Latinx men hospitalized with alcohol use disorder seen by an Addiction Consult Team by Mariam S. Carson, Alein Y. Haro-Ramos, Naomi López-Solano, Carla Fernandez, Marcus Cummins, Alicia Fernandez, Triveni DeFries, Marlene Martin

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Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection among Kidney Transplant Recipients: A Large Single-Center Experience by Emily E. Zona, Mina L. Gibes, Asha S. Jain, Juan S. Danobeitia, Jacqueline Garonzik-Wang, Jeannina A. Smith, Didier A. Mandelbrot, Sandesh Parajuli

“…Kidney transplant recipients (KTRs) are a vulnerable immunocompromised population at risk of severe COVID-19 disease and mortality after SARS-CoV-2 infection. …”
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Perspectives on AI-based recommendations for mask-wearing and COVID-19 vaccination for transplant recipients in the post-COVID-19 era by Oscar A. Garcia Valencia, Charat Thongprayoon, Jing Miao, Jackrapong Bruminhent, Iasmina M. Craici, Wisit Cheungpasitporn

“…Thus, this study utilizes AI, specifically ChatGPT 4.0, to assess its perspectives in offering precise health recommendations for mask-wearing and COVID-19 vaccination tailored to this vulnerable population. Through a series of scenarios reflecting diverse environmental settings and health statuses in December 2023, we evaluated the AI’s responses to gauge its precision, adaptability, and potential biases in advising high-risk patient groups. …”
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Treatment of Hepatitis C Post-Liver Transplantation Could Mitigate Discard Rates of Hepatitis C-Positive Deceased Donor Livers and Expand the Donor Pool by Jennifer Keller, Gary Marklin, Obi Okoye, Roshani Desai, Tej Sura, Ajay Jain, Chintalapati Varma, Mustafa Nazzal

“…Discard rate was significantly higher in the pre-DAA population (31.9% vs. 12.2%, p = 0.026). Secondary analysis showed a distinct trend towards increased regional sharing and utilization of HCV+ donors. …”
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Routine antibiotics for infants less than 6 months of age with growth failure/faltering: a systematic review by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Olivia Tsistinas, Emily Tanner-Smith, Melissa François, Fanny F Chen, Momal Sana

“…Objective This systematic review commissioned by WHO aimed to synthesise evidence from current literature on the effects of systematically given, routine use of antibiotics for infants under 6 months of age with growth failure/faltering.Settings Low-income and middle-income countries.Participants The study population was infants less than 6 months of age with growth failure/faltering.Intervention The intervention group was infants who received no antibiotics or antibiotics other than those recommended in 2013 guidelines by WHO to treat childhood severe acute malnutrition. …”
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Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…However, we lack concentrated data on the characteristics of this population and the transformed SCLC to aid our insight of the biology and clinical value of NSCLC transforming with positive. …”
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How does news coverage of suicide affect suicidal behaviour at a high-frequency location? A 7-year time series analysis by Lisa Marzano, Ruth Spence, Ian Kruger, Ian Marsh, Arianna Barbin

“…Introduction News reporting of suicide can have a significant influence on suicidal behaviour in the general population, especially following the death of a well-known individual. …”
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SSR analysis of the genomic DNA of perspective Uzbek hexaploid winter wheat varieties by A. T. Adylova, G. K. Norbekov, E. E. Khurshut, E. V.  Nikitina, F. N. Kushanov

“…The expected heterozygosity (He) ranged from 0 to 0.792, averaging 0.626, in studied wheat population. The amplified fragment sizes ranged from 93 to 552 bp. …”
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Expression of SIRT1 and DBC1 in Developing and Adult Retinas by Shawn C. Maloney, Emilia Antecka, Alexandre N. Odashiro, Bruno F. Fernandes, Madeline Doyle, Li-Anne Lim, Yousef Katib, Miguel N. Burnier

“…Moreover, we observed cytoplasmic DBC1 in a subset of progenitor cells as well as in mature ganglion cells, indicating that the progenitor cell subset, which was comprised predominantly of small cells, may represent a population of ganglion cell precursors. Collectively, the data presented in this study provide support for SIRT1 and DBC1 as regulators of retinal development and normal retinal physiology.…”
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