Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

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Evaluation of Arabic lesson teaching in higher education based on the Kirkpatrick model by Ali Akbar Mollaie, Mohammad Aslam Raiesi

“…Questionnaire was used in the field section. The statistical population of this study includes students of higher education institutions in Tehran. …”
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Investigating effective factors in the model of high organizational commitment in government organizations in charge of educational and cultural affairs by Seyed Alireza Mirjafari, Abdul Khaliq Gholami Anarestan, Karam Elah Daneshfard

“…Methodology: In terms of purpose, this research is practical, and in terms of research implementation method; survey-exploratory. The statistical population of the research includes managers and experts of government organizations in charge of educational and cultural affairs, which was considered as 396 people from the city of Tehran, and using the method of determining the sample size of Cochran's formula, 217 people were selected as a sample based on the formula Sampling calculated from the limited population, among which, as a sample, was distributed a researcher-made questionnaire prepared from the qualitative part of the research. …”
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Designing a model for re-employment of employees during retirement (Study case: Ministry of Education) by Fatemeh Fatemeh Bina Baji, Hamid Rezaei Far, Mohammad Mohammadi, Monireh Salehnia

“…The predictions of the United Nations (2017) indicate that by 2050, the population over 60 years old will be more than 4 times compared to the year 2000 (Dehghani et. al. 2019). …”
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FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn... by Kerry Woolfall, Jamie J Kirkham, Jane Sandall, Mariana Popa, Enrico Lopriore, Mark Turner, Shakila Thangaratinam, Aris T Papageorghiou, Andrew Sharp, Lawrence Impey, Andy Healey, Jessica Mendoza, Asma Khalil, Dharmintra Pasupathy, Brigitte Vollmer, Zarko Alfirevic, Rajeswari Parasuraman, Jan Deprest, Richard Edmund Ashcroft, Kurt Hecher, Smriti Prasad, Baskaran Thilaganathan, Richard J Jackson, Tracy Karen Mitchell, Natasha Fenwick, Monique C Haak, Liesbeth Lewi, Shauna Leven, Fabricio Da Silva Costa, Odai Yaghi, Tracey Ricketts, George Attilakos, Carolyn Bailie, Christine Cornforth, Mark Denbow, Louise Hardman, Jane Harrold, Joel Marsden, Tommy Mousa, Surabhi Nanda, Michelle Watson, Karen Wilding, Dilly Anumba, Edward D Johnstone, Yoav Yinon, Ahmet Baschat

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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…In fact, it is not possible to conduct a big number of tests and more importantly there are not joint studies on samples of population in the areas more at risk. After two months from the critical stage of the emergency, scientists still don’t know the level of immunity the Italian population has reached. …”

Cooperation-Based Modeling of Sustainable Development: An Approach from Filippov’s Systems by Jorge A. Amador, Johan Manuel Redondo, Gerard Olivar‐Tost, Christian Erazo

“…In this article, it is proposed that Sustainable Development should be interpreted as the capacity of territory, community, or landscape to conserve the notion of well-being that its population has agreed upon. To see the implications of this interpretation, a Brander and Taylor model, to evaluate the implications that extractivist policies have over an isolated community and cooperating communities, is proposed. …”
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The Impact of Technology Orientation on Export Performance with Emphasis on the Mediating Role of Innovation and Moderating Role of Corporate Social Responsibility by Ahmad Sadeghi, Mohammad Khodabakhshi, Zeinab Mir Ghasemi

“…The study's statistical population consisted of all manufacturers and exporters of detergent and sanitary products in Iran. …”
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Triglyceride levels and its association with all-cause mortality and cardiovascular outcomes among patients with heart failure by Qing-Wen Ren, Tiew-Hwa Katherine Teng, Wouter Ouwerkerk, Yi-Kei Tse, Christopher Tze Wei Tsang, Mei-Zhen Wu, Hung-Fat Tse, Adriaan A. Voors, Jasper Tromp, Carolyn S. P. Lam, Kai-Hang Yiu

“…Using a previously validated territory-wide clinical information registry, all eligible patients diagnosed with HF (N = 127124) from 2000 to 2020 were included. In this population-based cohort (mean age: 71.4 ± 12.2 years, 51.8% male), the association between triglyceride levels and risk of all-cause mortality and cardiovascular disease was a U-shapedḍ curve. …”
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Erectile Dysfunction Preceding Clinically Diagnosed α-Synucleinopathies: A Case-Control Study in Olmsted County by Shemonti Hasan, Michelle M. Mielke, J. Eric Ahlskog, James Bower, Pierpaolo Turcano, Rodolfo Savica

“…Erectile dysfunction (ED) is an autonomic symptom that has rarely been studied in these α-synuclein disorders. In this population-based, case-control study, we investigated the association between premonitory erectile dysfunction surfacing prior to the clinical-motor manifestations of these α-synucleinopathies. …”
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Butterfly Abundance and Diversity in Different Habitat Types in the Usangu Area, Ruaha National Park by Evaline J. Munisi, Emmanuel H. Masenga, Ally K. Nkwabi, Halima R. Kiwango, Eblate E. Mjingo

“…Preserving this wilderness to maintain a thriving butterfly population is of utmost importance.…”
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Passive acoustic monitoring of an elusive rail, the corncrake (Crex crex): Calling patterns, detectability and monitoring recommendations by Andrea Parisi, Marie Greaney, John Carey, James Moran, Joanne O’Brien

“…However, conservation projects need reliable population data to understand the species status and prioritise strategies. …”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Outcomes of interest included a 28-day overall response rate (ORR), a 28-day ORR in the grade III-IV aGVHD population, and adverse events (AEs). **Results:** In the full populations, the STC of risk ratios (RRs) found treatment with remestemcel-L-rknd to be associated with a numerical but not statistically significant improvement in the 28-day ORR versus ruxolitinib. …”
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France and The European Charter for Regional or Minority Languages: Dilemma without Solution by E. V. Ermakova

“…However, in addition to the French 75 languages are being spoken all over the Overseas Departments and Territories of France, including 24 languages of the indigenous population of the European part of France, and the languages of immigrants. …”
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Familial Aggregation and Risk Factors for Prostate Cancer in Affected Individuals by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara

“…<br /><strong>Method:</strong> an observational, analytical, longitudinal, and retrospective, case/control study was conducted on the population of the Banes municipality, Holguín province, between May 2021 and May 2022. …”
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Comparison of Characteristics of Breast Cancer Detected through Different Imaging Modalities in a Large Cohort of Hong Kong Chinese Women: Implication of Imaging Choice on Upcoming... by Yik Shuen Chan, Wai Ka Hung, Lok Wa Yuen, Ho Yan Yolanda Chan, Chiu Wing Winnie Chu, Polly Suk Yee Cheung

“…Mammogram has a good detection rate of cancers in our local population. It has superiority in detecting early cancers by detecting microcalcifications. …”
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Prospective evaluation of artificial intelligence (AI) applications for use in cancer pathways following diagnosis: a systematic review by Ajay Aggarwal, Richard Sullivan, Andrew Hope, Peng Yun Ng, Sheba Macheka

“…The role of artificial intelligence (AI) in cancer care has evolved in the face of ageing population, workforce shortages and technological advancement. …”
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Quantitative fluorescent nanoparticle tracking analysis and nano‐flow cytometry enable advanced characterization of single extracellular vesicles by Danilo Mladenović, Joseph Brealey, Ben Peacock, Kairi Koort, Nataša Zarovni

“…This standardization technique allowed for fluorescent EV signal to be expressed in ERF units (indicative of bound fluorescent antibodies per EV), thus enabling measurement of target protein marker abundance on individual EVs, and in the whole EV population. The NTA's and nFCM's limits of detection (LoD) were evaluated at 21 and 9 Alexa Fluor 488 (AF488) molecules, respectively. …”
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Evaluating the implementation and impact of a volunteer navigation oncology support programme: study protocol for a pragmatic, real-world hybrid type 2 study by Charlotte Waugh, Noah Federman, Gabrielle B Rocque, D'Ambra N Dent, Emily K Hill, Ian Bostock Rosenzweig, Bonny Morris, Arif Kamal

“…However, oncology practices are often resource constrained and lack the capacity to extend navigation services at the desired intensity for their patient population. The American Cancer Society (ACS) developed the ACS Community Access to Resources, Education, and Support (CARES) programme to expand navigation capacity through the training of students from local universities as volunteers to serve as non-clinical navigators to support cancer patients. …”
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