Cytisine compared to combination nicotine replacement therapy to reduce cigarette consumption in relapsed smokers: protocol for a pilot randomized controlled trial by Hassan Mir, Javad Heshmati, Kerri-Anne Mullen, Ashley Baldwin, Evyanne Quirouette, Andrew Pipe, Robert Reid

“…This study will also compare the acceptability, efficacy, and safety of cytisine compared to combination NRT, as demonstrated in previous studies in other populations. Notably, cytisine’s shorter regimen and natural composition broaden its appeal, potentially supporting a wider spectrum of people who smoke. …”
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Selection of promising apple genotypes for columnar growth habit and scab resistance using diagnostic DNA markers by N. I. Savel’ev, A. S. Lyzhin, N. N. Savel’eva

“…The purpose of this study was molecular genetic testing of initial forms of apple and hybrid seedlings of apple to identify carriers of the target alleles of genes for monogenic scab resistance (Rvi6) and columnar growth habit (Co) and the clarification of the pattern of inheritance of the Co and Rvi6 genes in hybrid progeny populations. This paper presents the results of molecular genetic analysis of varieties Valuta, Uspenskoe, Belarusskoe sladkoe and seedlings of the Valuta×Uspenskoe and Valuta×Belarusskoe sladkoe hybrid families for genes controlling columnar growth habit (Co) and scab resistance (Rvi6). …”
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Integrative single-cell and multi-omics analyses reveal ferroptosis-associated gene expression and immune microenvironment heterogeneity in gastric cancer by Shupeng Zhang, Zhaojin Li, Gang Hu, Hekai Chen

“…The microenvironment of gastric cancer is composed of diverse cell populations, yet the specific gene expression profiles and their association with ferroptosis are not well understood. …”
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Visual and Auditory fMRI Paradigms for Presurgical Language Mapping: Convergent Validity and Relationship to Individual Variables by Antonina Omisade, Christopher B. O’Grady, Matthias H. Schmidt, John D. Fisk

“…Despite this, there are currently no standardized fMRI protocols that have been explored in healthy controls to determine the influence of individual patient variables on the results, which poses challenges in clinical interpretation of ambiguous findings in patient populations. In addition, most fMRI protocols are not suitable for individuals with visual or intellectual disabilities (IQ<70). …”
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Analysis of functional and phylogenetic diversity of bat communities: insights from resource use in the Pantanal and Cerrado by Marcione B. de Oliveira, Luiz Flamarion B. de Oliveira, Cibele R. Bonvicino

“…Conclusion Our results showed, through analyses across multiple dimensions of functional and phylogenetic diversity, that bat populations are impacted by environmental degradation and fragmentation. …”
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Understanding the impact of racism on surgical outcomes in settler nation-states USA and Canada: a protocol for a systematic review and meta-analysis by Mary Brindle, Oluwatomilayo Daodu, Tyara Marchand, Saffa Aziz, Ifeoluwa Adedipe, Mirna Matta

“…Identifying preventable adverse outcomes for equity-deserving patient populations is an important starting point to begin to address these gaps in care. …”
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Therapeutic alliance during trauma focused treatment in adolescent and young adult patients with PTSD by Anne Grass, Rita Rosner, Angelina Ciner, Babette Renneberg, Regina Steil

“…Abstract Background Greater therapeutic alliance has been associated with an improved treatment outcome in various clinical populations. However, there is a lack of evidence for this association in posttraumatic stress disorder (PTSD) in young patients. …”
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Association of a novel nutritional index with cognitive impairment in middle-aged and elderly Chinese adults: a cross-sectional analysis from the China Health and Retirement Longit... by Guotao Liu, Jianyuan Zhang

“…This study explored the association between TCBI and cognitive impairment in middle-aged and elderly Chinese populations.Patients and methodsThis cross-sectional study employed data from the China Health and Retirement Longitudinal Study (CHARLS) baseline survey, including 7,145 participants. …”
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Principles of Rational Nutrition for Managing Constipation by Yu. O. Shulpekova, D. A. Sheptulin, N. V. Shulpekova

“…A low content of fibre in the diet is a factor provoking intestinal dysbiosis followed by a decrease in  Bacteroides and Ruminococcus populations. Flavonoids also play an important role in the regulation of intestinal peristalsis and secretion. …”
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Skin Closure Technique and Postprocedural Pain after Spinal Cord Stimulator Implantation: A Retrospective Review by Markus A. Bendel, Ryan S. D’Souza, Taylor J. North, Thomas P. Pittelkow, Jonathan M. Hagedorn

“…There is a paucity of data related to defining best practices in these specific patient populations, and historically, providers have relied on consensus committees to opine on the best techniques for patient safety and experience. …”
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Generalizability of Randomized Clinical Trial Outcomes for Diabetes Control Resulting From Bariatric Surgery by Edward H. Livingston, MD, FACS, AGAF, Hila Zelicha, RD, PhD, Erik P. Dutson, MD, Zhaoping Li, MD, PhD, Matthew L. Maciejewski, PhD, Yijun Chen, MD

“…There is a need to assess how the results of RCTs generalize to all contemporary patient populations undergoing treatments. Methods:. All patients undergoing sleeve gastrectomy at University of California Los Angeles (UCLA) between January 8, 2018 and May 19, 2023 had their baseline characteristics, weight change, and diabetes control compared with those enrolled in the surgical treatment and medications potentially eradicate diabetes efficiently (STAMPEDE) and diabetes surgery study (DSS) RCTs of bariatric surgery’s effect on diabetes control. …”
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Factors associated with adherence to antiretroviral therapy among HIV-positive adolescents and young adult patients attending HIV care and treatment clinic at Bombo Hospital in Tan... by Sophia Kamote, Novatus Apolinary Tesha, Bruno F Sunguya

“…However, adherence to ART is lower among adolescents compared to other sub-populations and even lower in sub-Saharan Africa. The factors influencing ART adherence are context-specific and vary across countries and regions. …”
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Legal foundations of the organization and activities of the Ukrainian SSR police in 1949–1950s by О. V. Brusakova, V. A. Hrechenko

“…The practical activity of police bodies for the protection of public order was determined by the following directions: 1) administrative activity (patrol in populated areas, compliance with the rules of the passport and permit system, regulation of street traffic); 2) involvement of state institutions, public organizations and citizens in cooperation; 3) creation of voluntary formations - police assistance brigades and public order protection groups.…”
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Platelet-to-lymphocyte ratio as a biomarker of systemic inflammation in systemic lupus erythematosus: A meta-analysis and systematic review. by Young Ho Lee, Gwan Gyu Song

“…Upon stratification by ethnicity, an elevated PLR was observed in the SLE group among both Asian and Arab populations. Subgroup analysis based on sample size revealed consistently higher PLR in both small (n < 200) and large sample (n ≥ 200) SLE groups. …”
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NOL-7 serves as a potential prognostic-related biomarker for hepatocellular carcinoma by Qiucheng Lei, Yingchun Huang, Feiwen Deng, Huazhen Zheng, Xitao Hong, Peng Wang, Jin Lv, Huanwei Chen, Zhenling Ji

“…In addition, NOL7 expression was significantly correlated with cell cycle modulators, immune checkpoints, and various immune cell populations. In addition, we identified eight potential pathways associated with NOL7 as the most promising pathways for NOL7 in HCC. …”
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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…Knowledge of the epidemic and the Routes of transmission of this pathogen are important points to avoid from spreading and may be useful in identifying high-risk populations, especially in areas that have high rates of gastric lymphoma, gastric cancer, and gastric ulcer. …”
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Risk factors for the mortality of hemodialysis patients with COVID-19 in northern Hunan province, China by Zhangxiu He, Zhong Peng, Ning Gao, Shuzhu Zhong, Fengyi Yu, Zixu Tang, Zihao Liao, Song Zhao, Gloria Umwiza, Ming Chen, Wei Long

“…Conclusion We discovered that old age, high levels of NWR and PCT might be predictors of mortality, reported the causes and prognostic predictors of mortality in hemodialysis populations with COVID-19 from northern Hunan, China.…”
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Are interventions for low-income groups effective in changing healthy eating, physical activity and smoking behaviours? A systematic review and meta-analysis by Stephan U Dombrowski, Marie Johnston, Nicola McCleary, Eleanor R Bull

“…Further work is needed to improve the effectiveness of behaviour change interventions for deprived populations.…”
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Predictors of Neonatal Jaundice Admissions: A Comparative Study Between Thai and Myanmar Mothers Residing in Thailand by Eksamut W, Rungamornrat S, Payakkaraung S

“…Strengthening bilingual education, culturally tailored healthcare support, and expanding resources for migrant populations are essential to reducing disparities and improving neonatal outcomes in low- and middle-income countries.Keywords: maternal health literacy, neonatal jaundice, preventive practices, immigrant mothers, low- and middle-income countries (LMICs)…”
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Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice by Sherry T. Shu, Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E. Smithgall

“…Both CC-Hck and CC-Fgr cell populations became sensitized to growth arrest by Src-family kinase inhibitors previously shown to suppress the growth of bone marrow cells from AML patients in vitro and decrease AML cell engraftment in immunocompromised mice. …”
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