Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens by Christine Wu, Parmjeet Randhawa, Jerry McCauley

“…BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community. …”
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Molecular Networks Involved in the Immune Control of BK Polyomavirus by Eva Girmanova, Irena Brabcova, Jiri Klema, Petra Hribova, Mariana Wohlfartova, Jelena Skibova, Ondrej Viklicky

“…BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. …”
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Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection by Yoliswa Z. Chili, Menzi B. Nkosi, Nicky-Louise Byrne, Moepeng J. Maseko, Stephen N.J. Korsman, Gert U. Van Zyl

Subjects: “…haemorrhagic cystitis, cll, adenovirus, bk polyomavirus…”
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Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches by Cillian F. De Gascun, Michael J. Carr

“…JC and BK polyomaviruses were discovered over 40 years ago and have become increasingly prevalent causes of morbidity and mortality in a variety of distinct, immunocompromised patient cohorts. …”
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Adjuvant Ciprofloxacin for Persistent BK Polyomavirus Infection in Kidney Transplant Recipients by David Arroyo, Sindhu Chandran, Parsia A. Vagefi, David Wojciechowski

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Review on the Relationship between Human Polyomaviruses-Associated Tumors and Host Immune System by Serena Delbue, Manola Comar, Pasquale Ferrante

“…The polyomaviruses are small DNA viruses that can establish latency in the human host. …”
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Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus by Ilaria Bononi, Elisa Mazzoni, Silvia Pietrobon, Maria Rosa Iaquinta, Andrea Caselli, Elena Torreggiani, Maura Pugliatti, Ilaria Casetta, Massimiliano Castellazzi, Enrico Granieri, Fernanda Martini, Mauro Tognon

“…The aim of our study is to verify the association between the polyomavirus BKPyV and MS, together with other neurological diseases, through the investigation of serum IgG antibodies against the virus. …”
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A Case Report of Avian Polyomavirus Infection in a Blue Fronted Parrot (Amazona aestiva) Associated with Anemia by Natalia Azevedo Philadelpho, Marta B. Guimarães, Antonio J. Piantino Ferreira

“…Because the animal was positive for APV in both the feces and the blood, it is likely that these clinical symptoms were due to Polyomavirus infection. Severe anemia is an unusual clinical sign of Polyomavirus, and this study aims to identify novel differential diagnostic criteria for the disease.…”
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Frequency of BK virus genotypes in patients with colorectal cancer by Mahsa Javadi, Gholamabbas Kaydani, Roya Pirmoradi, Abdolhassan Talaiezadeh, Azadeh Haghi Navand, Mohammad Karimi Baba Ahmadi, Manoochehr Makvandi

Subjects: “…BK polyomavirus;…”
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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case report by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

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Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome by Aiden M. C. Pike, Saeed Amal, Melissa S. Maginnis, Michael P. Wilczek

Subjects: “…JC polyomavirus…”
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Control of BKPyV-DNAemia by a Tailored Viro-Immunologic Approach Does Not Lead to BKPyV-Nephropathy Progression and Development of Donor-Specific Antibodies in Pediatric Kidney Tra... by Michela Cioni, Stella Muscianisi, Marica De Cicco, Sabrina Basso, Hans H. Hirsch, Iris Fontana, Laura Catenacci, Jessica Bagnarino, Mariangela Siciliano, Oriana Montana Lampo, Gloria Acquafredda, Lou Tina Diana Boti, Jessica Rotella, Eleonora Bozza, Jennifer Zumelli, Kristiana Mebelli, Fausto Baldanti, Massimo Cardillo, Marco Zecca, Arcangelo Nocera, Mario Luppi, Enrico Verrina, Fabrizio Ginevri, Patrizia Comoli

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A Review on JC Virus Infection in Kidney Transplant Recipients by Serena Delbue, Mariano Ferraresso, Luciana Ghio, Camilla Carloni, Silvia Carluccio, Mirco Belingheri, Alberto Edefonti, Pasquale Ferrante

“…The polyomavirus (PyV), JC virus (JCV), is a small nonenveloped DNA virus that asymptomatically infects about 80% of healthy adults and establishes latency in the kidney tissue. …”
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Cerebellar Involvement in an Immunocompetent Patient Presenting with Progressive Multifocal Leukoencephalopathy by Rafael Garcia-Carretero, Blanca San Jose Montano

“…Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by the JC virus, a polyomavirus that can be reactivated under certain immunosuppressive conditions, such as AIDS, immunomodulatory therapy, and haematological malignancies. …”
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Parvovirus Infection-Related Anemia after Kidney Transplantation by Neeraj Sharma, Ranvir Bajwa

“…Infections, including those due to parvovirus B19, CMV, and BK virus (polyomavirus), have also been associated with an increased risk of anemia. …”
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Merkel Cell Carcinoma: The Past, the Present, and the Future by Inamaria Erovic, Boban M. Erovic

“…In this review, we will illustrate the historical background of the Merkel cell carcinoma beginning with the 19th century, the first description of the Merkel cell to the finding of the CK20 as a highly specific diagnostic marker and finally to the recently detected Merkel cell polyomavirus (MCPyV). Moreover, we will highlight the beginning of adjuvant therapeutic regimens with radiotherapy and chemotherapy and discuss the diagnostic work-up including imaging and histology of patients with Merkel cell carcinoma. …”
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Which Are the Cells of Origin in Merkel Cell Carcinoma? by Thomas Tilling, Ingrid Moll

“…Merkel cell carcinoma (MCC), a highly aggressive skin tumour with increasing incidence, is associated with the newly discovered Merkel cell polyomavirus (MCPyV). Studies on MCC and MCPyV as well as other risk factors have significantly increased our knowledge of MCC pathogenesis, but the cells of origin, which could be important targets in future therapies, are still unknown. …”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…Abstract Background Human polyomaviruses (HPyVs), JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV), have been found in upper tract urothelial carcinoma UTUC; however, the association of the viral oncogenic factors and clinical characteristics of UTUC remains unclear. …”
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Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases by Linda Zhou, Thomas H. Leung

“…We validate our pipeline with 100% sensitivity and specificity by (i) detecting Merkel cell polyomavirus in Merkel cell carcinoma samples, (ii) detecting specific human papillomavirus strains in known human papillomavirus–positive tumors, and (iii) detecting rubella virus transcripts in patients with known rubella-associated granulomas. …”
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Modeling BK Virus Infection in Renal Transplant Recipients by Nicholas Myers, Dana Droz, Bruce W. Rogers, Hien Tran, Kevin B. Flores, Cliburn Chan, Stuart J. Knechtle, Annette M. Jackson, Xunrong Luo, Eileen T. Chambers, Janice M. McCarthy

“…One pathogen of particular concern is human polyomavirus 1, also known as BK virus (BKPyV). This virus attacks kidney tubule epithelial cells and is a direct threat to the health of the graft. …”
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