The validity of the renal Doppler resistivity index in renal allograft infections by Moataz Fatthy, Karim M. Soliman, Éva Csongrádi, Abd El Rahman Marzouk, Ahmed Fathy, Ahmed Fayed

“…Based on laboratory and histopathological findings, 64 renal-allograft recipients were recruited for the infected group, and 45 were recruited for the non-infected group.Results The causes of allograft infection were Cytomegalovirus (CMV) infection (30.3%), urinary tract infections (UTI) (18.3%), and polyomavirus 1 (BK virus) infections (10.1%). There was a statistically significant difference in RRI in those with allograft infections, with the ROC curve for detection of infection utilizing RRI demonstrated an Area Under Curve 0.634 (p-value 0.015; cutoff value: 0.765; CI:0.527–0.742), with a specificity of 64.4% and a sensitivity of 68.8%.Conclusion Normal renal graft arterial resistivity index values, despite a renal allograft dysfunction, may be indicative of allograft infection, guiding clinicians’ decisions regarding kidney biopsy and facilitating further biopsy interpretations.…”
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Performance evaluation of the Qiagen BK virus ASR on the NeuMoDx system by Amorce Lima, Luciano Soares, Caroline Simmons, Laura Rowe, Dominic Uy, Deanna Becker, Suzane Silbert

“…Background: BK virus (BKV) is the main cause of polyomavirus‐associated nephropathy in kidney transplant patients and hemorrhagic cystitis in bone marrow recipients. …”
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Prevalence of Anti-JC Virus (JCV) Antibodies in the Multiple Sclerosis (MS) Population in Cyprus: A Retrospective Study by Sakis Lambrianides, Christiana A. Demetriou, Andis Tillyris, Elena Kkolou, Eftychia Gaglia, Eleni Agkastinioti, Eleni Leonidou, Yiolanda-Panayiota Christou, Savvas S. Papacostas, Kleopas A. Kleopa, Theodoros Kyriakides, Marios Pantzaris

“…Progressive multifocal leukoencephalopathy (PML) is a debilitating disease of the central nervous system caused by the ubiquitous polyomavirus JC (JCV) in immunocompromised hosts. In recent years, a new subpopulation of patients at risk for PML has emerged, due to the growing use of immunomodulatory or immunosuppressive therapies in autoimmune diseases such as multiple sclerosis (MS). …”
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Target-specific peptides for BK virus agnoprotein identified through phage display screening: advancing antiviral therapeutics by Xiaofei Xing, Jingxian Han, Keke Wang, Fuyun Tian, CuiXia Jiang, Wei Liang, Lin Qi, Xin Yue, Yinhang Wen, Yuwei Hu, Hui Qiao

“…Abstract BK virus is implicated in polyomavirus-associated nephropathy (PVAN) and hemorrhagic cystitis, particularly in kidney transplant recipients, affecting the functionality of the transplanted kidney and posing a risk of graft loss. …”
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Logistic Regression Model in a Machine Learning Application to Predict Elderly Kidney Transplant Recipients with Worse Renal Function One Year after Kidney Transplant: Elderly KTbo... by Ubiracé Fernando Elihimas Júnior, Jamila Pinho Couto, Wallace Pereira, Michel Pompeu Barros de Oliveira Sá, Eduardo Eriko Tenório de França, Filipe Carrilho Aguiar, Diogo Buarque Cordeiro Cabral, Saulo Barbosa Vasconcelos Alencar, Saulo José da Costa Feitosa, Thais Oliveira Claizoni dos Santos, Helen Conceição dos Santos Elihimas, Emilly Pereira Alves, Marcio José de Carvalho Lima, Frederico Castelo Branco Cavalcanti, Paulo Adriano Schwingel

“…No significant differences (P>0.05) between groups were observed after KT on laboratory data means and for the prevalences of diabetes mellitus, hypertension, acute rejection, cytomegalovirus, polyomavirus, and urinary infections. One year after KT, the creatinine clearance was higher (P = 0.006) in youngers (70.9 ± 25.2 mL/min/1.73 m2) versus elderlies (53.3 ± 21.1 mL/min/1.73 m2). …”
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Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice by Marit Hjorth, Casey L. Egan, Guilherme D. Telles, Martin Pal, David Gallego-Ortega, Oliver K. Fuller, Emma D. McLennan, Ryan D. Gillis, Tae Gyu Oh, George E.O. Muscat, Surafel Tegegne, Michael S.M. Mah, Joanna Skhinas, Emma Estevez, Timothy E. Adams, Matthew J. McKay, Mark Molloy, Kevin I. Watt, Hongwei Qian, Paul Gregorevic, Thomas R. Cox, Pernille Hojman, Julie Midtgaard, Jesper F. Christensen, Martin Friedrichsen, Renato V. Iozzo, Erica K. Sloan, Brian G. Drew, Jørgen F.P. Wojtaszewski, Martin Whitham, Mark A. Febbraio

“…Results: We show that voluntary wheel running slows tumor development in the mammary specific polyomavirus middle T antigen overexpression (MMTV-PyMT) mouse model of breast cancer but only when mice are not housed alone. …”
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Comparing Effects of BK Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression by Michela Cioni, Christian Mittelholzer, Marion Wernli, Hans H. Hirsch

“…Background. Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. …”
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