3D-Printed PCL-Based Scaffolds with High Nanosized Synthetic Smectic Clay Content: Fabrication, Mechanical Properties, and Biological Evaluation for Bone Tissue Engineering by Furtado ASA, Cunha MHS, Sousa LMR, Brito GC, Verde TFCL, Filgueiras LA, Sobral-Silva LA, Santana MV, Sousa GF, Santos FEP, Mendes AN, Figueredo-Silva J, Maia Filho ALM, Marciano FR, Vasconcellos LMR, Lobo AO

“…The main challenge lies in achieving a uniform distribution of nanoceramics across low to high concentrations within the polymer matrix while preserving mechanical properties and biological performance essential for successful osseointegration.Methods: This study utilized 3D printing to fabricate PCL scaffolds enriched with nanosized synthetic smectic clay (LAP) to evaluate its effects on structural, chemical, thermal, mechanical, and degradative properties, with a focus on in vitro biological performance and non-toxicity. …”
Get full text

Production, Characterization, and In Vitro Antifungal Evaluation of Itraconazole-Loaded Fibrous Sheets Prepared by Electrospinning with a Factorial Design by Emőke-Margit Rédai, Orsolya Péterfi, Attila Levente Gergely, Enikő Barabás, Andrada Pintea, Paula Antonoaea, Robert-Alexandru Vlad, Nicoleta Todoran, Cornelia-Titiana Cotoi, Adriana Ciurba, Emese Sipos

“…The obtained fiber mats prepared from the hydrophilic polymer presented almost instantaneous disintegration, with potential applications for rapid antifungal delivery in oral or topical pharmaceutical form.…”
Get full text

Bioactive Coatings on 3D Printed Polycaprolactone Scaffolds for Bone Regeneration: A Novel Murine Femur Defect Model for Examination of the Biomaterial Capacity for Repair by Karen M. Marshall, Jonathan P. Wojciechowski, Vineetha Jayawarna, Abshar Hasan, Cécile Echalier, Sebastien J. P. Callens, Tao Yang, Janos M. Kanczler, Jonathan I. Dawson, Alvaro Mata, Manuel Salmeron‐Sanchez, Molly M. Stevens, Richard O. C. Oreffo

“…In summary, Laponite/BMP‐2 coated PCL‐TMA900 scaffolds offer a biodegradable, osteogenic construct for bone augmentation with potential for development into a large scale polymer scaffold for clinical translation.…”
Get full text

Preparation of Tragopogon graminifolius-loaded electrospun nanofibers and evaluating its wound healing activity in a rat model of skin scar by Leila Almasi, Elham Arkan, Mohammad Hosein Farzaei, Amin Iranpanah, Cyrus Jalili, Fatemeh Abbaszadeh, Faranak Aghaz, Sajad Fakhri, Javier Echeverría

“…To evaluate the wound healing effects, rats were divided into four distinct groups, including negative control (untreated), phenytoin cream (as positive control), polymer (PVA/PEO/CS), and drug (nanofiber-containing 50% of TG extract; named PVA/PEO/CS/TG) groups. …”
Get full text

Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor‐Associated Macrophage by Xiaojiao Sun, Junling Zhang, Bingqi Dong, Qingqing Xiong, Xin Wang, Yanlun Gu, Zhiqi Wang, Huiyu Liu, Jixin Zhang, Xu He, Hongjin Liu, Yi Zhong, Chuxiao Yi, Xiaowei Chi, Zhenming Liu, Xiaocong Pang, Yimin Cui

“…Finally, pharmacological inhibition of SLITRK4 by using lipid‐polymer hybrid nanoparticles (NPs) for systemic siRNA delivery can effectively inhibit CRC liver metastasis. …”
Get full text

Spatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery by Yuta Takahashi, Riki Oshika, Rie Tachibana, Katsuyuki Shirai, Hiroshi Asakura, Masayoshi Miyazaki, Tomohiro Sagawa, Shinichi Takahashi, Tsunekazu Kuwae, Hironori Kojima, Shiro Nishiyama, Hikaru Nemoto, Yoshitomo Ishihara, Mariko Umeda, Kotaro Kijima, Daisuke Kobayashi, Keiji Suzuki, Yuki Nozawa, Kento Hoshida, Tomoki Kitagawa, Hiromitsu Endo, Yuki Matsunaga, Hiroya Itagaki, Mayumi Ishida, Shigeru Kanahara, Ryo Horita, Daisuke Hori, Hidenobu Tachibana

“…A multi-institutional 3D starshot test using beams from seven directions was conducted at 22 clinics using Varian and Elekta linacs with X-ray CT-based polymer gel dosimeters. Variability in dose delivery accuracy was observed, with the distance between the imaging isocenter and each beam exceeding 1 mm at one institution for Varian and nine institutions for Elekta. …”
Get full text

In-vitro and in-vivo assessment of biocompatibility and efficacy of ostrich eggshell membrane combined with platelet-rich plasma in Achilles tendon regeneration by Omid Koohi-Hosseinabadi, Reza Shahriarirad, Amireza Dehghanian, Laleh Amini, Sajjad Barzegar, Afrooz Daneshparvar, Omid Alavi, Seyedeh-Parvin Khazraei, Saba Hosseini, Ali Arabi Monfared, Roya Khorram, Nader Tanideh, Soheil Ashkani-Esfahani

“…Ostrich eggshell membrane (ESM), characterized by a strong preferential orientation of calcite crystals, forms a semipermeable polymer network with excellent mechanical properties compared to membranes from other bird species, emerging as a potential natural scaffold candidate. …”
Get full text

Advanced TiO2-polypyrrole nanostructures enhance glucose detection accuracy with cutting-edge non-enzymatic electrochemical capabilities by Ashima Thakur, Sweety Pal, Usha Sharma, Ajit Sharma, Meenakshi Choudhary, Mukesh C. Joshi, Herma Dina Setiabudi, Prabal Pratap Singh, Atheesha Singh, Sudheesh K. Shukla

“…The developed non-enzymatic glucose detection sensor demonstrated sensitivity of 678.57 μAmM−1cm2 with linear range of 0 mM to 5.5 mM The enhanced performance is attributed to the synergistic effects of both the metallic as well as polymer moieties in the nanocomposite, where polypyrrole provides an outstanding conductive network for an efficient electron transfer, while TiO2 offers an active Centre for oxidation of glucose molecule. …”
Get full text

Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration by Lei Yu, Wentao Wang, Chang Lv, Qian Chen, Peng Yang, Zhenrong Qi, Haomiao Yu, Ruiqi Cao, Wenhao Li, Yi Qin, Gaoran Ge, Peilai Liu, Lixin Zhu, Houyi Sun, Dechun Geng, Liang Zhang

“…Despite the development of various polymer scaffolds for bone defect repair, achieving effective regeneration in osteoporotic bones—especially when combined with osteoporosis medications—remains difficult. …”
Get full text

Application of artificial neural networks for predictive model of municipal solid waste collection in tourist cities by T. Kridakorn Na Ayutthaya, N. Jakrawatana, D. Rinchumphu, V. Owatsakul

“…The study also pinpointed seven specific polymer classifications, which consist of polyethylene, polypropylene, polystyrene, nylon, polyester, polybutadiene, and polyethylene terephthalate.CONCLUSION:  The escalating levels of microplastics in the environment present a substantial threat to food security, marine ecosystems, and human health. …”
Get full text

3D Printed Swordfish‐Like Wireless Millirobot by Xingcheng Ou, Yu Sheng, Jiaqi Huang, Dantong Huang, Xiaohong Li, Ran Bi, Guoliang Chen, Weijie Hu, Shuang‐Zhuang Guo

“…The robot includes a silicone‐based torso (body, abdomen, and pectoral fin) and a crescent‐shaped tail fin made from a magnetically programmable polymer embedded with neodymium‐iron‐boron (NdFeB) particles. …”
Get full text

Microplastic contamination in the gut and gills of commercial marine fish by . Nurhasanah, . Hasrianti, L. Hakim, E. Riani, M.Y. Iswari, M.R. Cordova

“…The study also pinpointed seven specific polymer classifications, which consist of polyethylene, polypropylene, polystyrene, nylon, polyester, polybutadiene, and polyethylene terephthalate.CONCLUSION:  The escalating levels of microplastics in the environment present a substantial threat to food security, marine ecosystems, and human health. …”
Get full text

Novel Drug Delivery Particles Can Provide Dual Effects on Cancer “Theranostics” in Boron Neutron Capture Therapy by Abdul Basith Fithroni, Haruki Inoue, Shengli Zhou, Taufik Fatwa Nur Hakim, Takashi Tada, Minoru Suzuki, Yoshinori Sakurai, Manabu Ishimoto, Naoyuki Yamada, Rani Sauriasari, Wolfgang A. G. Sauerwein, Kazunori Watanabe, Takashi Ohtsuki, Eiji Matsuura

“…We have previously reported on self-forming nanoparticles for drug delivery consisting of a biodegradable polymer, namely, “AB-type” Lactosome^® nanoparticles (AB-Lac particles)- highly loaded with hydrophobic B compounds, namely <i>o</i>-Carborane (Carb) or 1,2-dihexyl-<i>o</i>-Carborane (diC6-Carb), and the latter (diC6-Carb) especially showed the “molecular glue” effect. …”
Get full text

In Situ Growth of (−201) Fiber‐Textured β‐Ga2O3 Semiconductor Tape for Flexible Thin‐Film Transistor by Xiao Tang, Yue Zhao, Kuang‐Hui Li, Chen Liu, Hendrik Faber, Wedyan Babatain, Che‐Hao Liao, Saravanan Yuvaraja, Vishal Khandelwal, Dhanu Chettri, Haicheng Cao, Yi Lu, Chuanju Wang, Thomas D. Anthopoulos, Xixiang Zhang, Xiaohang Li

“…Abstract High‐temperature in situ growth of Ga2O3 thin film on flexible substrates for flexible/portable electronic devices is never realized because the conventional polymer substrates cannot meet the thermal‐stability requirements. …”
Get full text

Experimental Study of Modified Videman Method to Replicate Knee Osteoarthritis in Rabbits by Jing LIU, Qiaoxuan LIN, Liming LU, Zexing GUO, Hong LIU, Liangzhi ZHANG, Zhongbiao XIU

“…In the improved group, a plaster support was placed on the front of the knee and wrapped a single layer of polymer plaster in a ring. The left knee joint of the rabbit was fixed in a straight position for 6 weeks for modeling, according to the modeling principle of the traditional group. …”
Get full text

Exploring aneuploidies in two-center isolated bovine embryonic stem cell lines: Implications for cultured meat production by Chloë Deelkens, Elly De Vlieghere, Mario Van Poucke, Masaki Kinoshita, Jeffrey Aalders, Lieven Thorrez, Bert Devriendt, Ann Van Soom, Luc Peelman, Björn Menten, Catharina De Schauwer, Jolanda van Hengel

Get full text

Preparation of Multicore Millimeter-Sized Spherical Alginate Capsules to Specifically and Sustainedly Release Fish Oil by Lina Tao, Panpan Wang, Ting Zhang, Mengzhen Ding, Lijie Liu, Ningping Tao, Xichang Wang, Jian Zhong

“…The simple monoaxial dispersion electrospraying-ionotropic gelatin technique does not involve complicated preparation formulations and polymer modification, which makes the technique has a potential application prospect for the fish oil preparations and the encapsulation of functional active substances in the field of food and drug industries.…”
Get full text

Roadmap on specialty optical fibers by Mário F S Ferreira, Mohd Rehan, Vishwatosh Mishra, Shailendra Kumar Varshney, Francesco Poletti, Nguyen Phuoc Trung Hoa, Weichao Wang, Qinyuan Zhang, Wenyu Du, Benli Yu, Zhijia Hu, Xian Feng, Jindan Shi, Anjali, Sunil Kumar, Michal Kamrádek, Mukul Chandra Paul, Kazi Abedin, Bertrand Kibler, Frédéric Smektala, Xiushan Zhu, Andrey Pryamikov, Stephan Reitzenstein

“…This rapidly evolving field calls on the expertise and skills of a broad set of different disciplines: materials science, ceramic engineering, optics, electrical engineering, physics, polymer chemistry, and several others. This roadmap on specialty optical fibers addresses different technologies and application areas. …”
Get full text

Biodegradable Mg alloy modified with bioactive exosomes for cardiovascular stent application by Ya-chen Hou, Jing-an Li, Chang Cao, Chang Su, Zhen Qin, Ge Zhang, Jia-cheng Guo, Jun-nan Tang, Jin-ying Zhang, Shao-kang Guan

“…In this work, the biodegradable Mg-Zn-Y-Nd alloy was modified by MgF2 and dopamine polymer film (PDA) as the corrosion resistance layer and the bonding layer respectively, and then the exosome, a natural nanoparticle contains mRNAs and proteins, was tailored to give the surface better biocompatibility. …”
Get full text

Peritoneal chemotherapy delivery systems for ovarian cancer treatment: systematic review of animal models by Marcelo Simonsen, Marcelo Simonsen, Rossana Verónica Mendoza López, Simone Maistro, Lucas Takeshi Ikeoka, Glaucia Fernanda de Lima Pereira, Ademar Benévolo Lugão, José Carlos Sadalla, Maria Lúcia Hirata Katayama, Maria Aparecida Azevedo Koike Folgueira

“…Intraperitoneal device, also known as drug delivery systems (DDS), consisted in nanoparticles, hydrogels, lipid polymer and others. The most commonly used drugs were paclitaxel and cisplatin. …”
Get full text