Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis by Yan Zhang, Xiujuan Chen, Yuan Lin, Xiaoqing Liu, Xiumei Xiong

“…BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic condition impacting millions of women worldwide. …”
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Variability of anti-Müllerian hormone and folliculotropic hormone levels in women of reproductive age in relation to normal or impaired ovarian function by Małgorzata Jusiakowska-Piputa, Maria Kaczmarek

“…The purpose of this study was to examine the variability of ovarian reserve markers with age in women with premature ovarian insufficiency (POI) and polycystic ovary syndrome (PCOS) in relative to women with normal ovarian function. …”
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Metabolic control of ovarian function through the sympathetic nervous system: role of leptin by Camila Astudillo-Guerrero, Alfonso H. Paredes, Jorge Escobar, Daniela Fernandois, Rafael Barra, Gonzalo Cruz

“…This suggests that the hyperactivation of sympathetic nerves in adulthood, due to metabolic programming, could be a possible cause of reproductive and metabolic disorders, such as polycystic ovary syndrome.…”
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黄体生成素β亚基Trp8Arg和Ile15Thr突变与多囊卵巢综合征 by 张二红, 梁晓燕, 曾海涛, 杜静, 骆春启, 庄广伦

“…【目的】探讨黄体生成素(luteinizing hormone,LH)β亚基Trp8Arg和Ile15Thr突变与中国人多囊卵巢综合征(polycystic ovary syndrome,PCOS)的关系。【方法】采用聚合酶链反应-限制性片段长度多态性分析(PCR-RFLP)技术检测113例PCOS患者和68例正常妇女,分析LHβ亚基基因突变与PCOS之间的关系。…”
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Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS: A SystematicReview of RCTs and Insight into the Underlying Mechanism by Shan Guo, Reshef Tal, Haoyu Jiang, Tao Yuan, Ying Liu

“…Evidence suggests that vitamin D deficiency correlated with metabolic disorders in women with polycystic ovary syndrome (PCOS). We conducted this systematic review and meta-analysis to evaluate the impact of vitamin D supplementation alone on glucose, lipid, and androgen parameters and inflammation biomarkers in women with PCOS. …”
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Diet diversity score might be associated with reproductive health in women and infant outcomes: a systematic review by Paniz Ahmadi, Niloofar Bayat, Behnood Abbasi

“…Due to our results, a higher score in DDS, which led to an increased intake of major nutrients and a greater variety of foods, was correlated with a lower risk of reproductive health disorders such as polycystic ovary syndrome, maternal anaemia, and maternal bone status, as well as a reduced likelihood of certain birth outcomes, including low-birth weight infants, Apgar score and congenital heart defect. …”
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Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study by Swati Dhar, Reena Yadav, Akash Tomar

“…It is unclear if serum zinc levels are correlated with polycystic ovary syndrome (PCOS) and its pathophysiology, although relation between diabetes and insulin resistance has been established. …”
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MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue by Tung-Yueh Chuang, Hsiao-Li Wu, Chen-Chun Chen, Gloria Mabel Gamboa, Lawrence C. Layman, Michael P. Diamond, Ricardo Azziz, Yen-Hao Chen

“…We previously reported that adipose tissue (AT) from women with polycystic ovary syndrome (PCOS) or controls with insulin resistance (IR) revealed a differentially expressed microRNA (miRNA) profile, including upregulated miR-93 in PCOS patients and in non-PCOS women with IR. …”
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Impact of dapagliflozin on metabolic phenotype, hormone levels, and fertility in female mice after prolonged high-fat diet by Xiaolin Chen, Zhuoni Xiao, Na Dai, Mingxia Fan

“…The sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as a treatment for type 2 diabetic patients, regulating adipose tissue metabolism, hypothalamic inflammation, and ovulation in women with polycystic ovary syndrome (PCOS). The study aimed to investigate the pharmacological effects of dapagliflozin on improving insulin resistance, energy metabolism, sex hormones, and fertility in female mice following prolonged consumption of HFD.MethodsAt 6 weeks of age, female mice were fed a HFD and treated with dapagliflozin. …”
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Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients by Jingwen Gan, Jie Chen, Rui-lin Ma, Yan Deng, Xue-song Ding, Shi-yang Zhu, Ai-jun Sun

“…Background. Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age, whose clinical characteristics are hyperandrogenism (HA), ovulatory dysfunction, and polycystic ovary, often accompanied by insulin resistance (IR) and metabolic abnormalities. …”
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Investigation of the Relationship between Chronic Endometritis Manifestations under Hysteroscope and CD138 Expression by Shuang Wang, FengHua Li, Wei Zhang, XiaoLong Sui, CuiFang Hao

“…In the comparison of overall status for all patient cohorts, infertility type, BMI, bFSH, bLH, bP, bT, PRL, AMH, and CA125 were varied markedly across all cohorts (P<0.05), with predominant incidences of polycystic ovary syndrome (PCOS) peaking within hyperemia cohort. …”
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Antioxidant therapy for infertile couples: a comprehensive review of the current status and consideration of future prospects by Ramadan Saleh, Ramadan Saleh, Hassan Sallam, Hassan Sallam, Mohamad AlaaEldein Elsuity, Mohamad AlaaEldein Elsuity, Sulagna Dutta, Sulagna Dutta, Pallav Sengupta, Ahmed Nasr

“…In women, OS is implicated in various reproductive disorders, including polycystic ovary syndrome, endometriosis, and premature ovarian failure, leading to diminished oocyte quality, disrupted folliculogenesis, and poorer reproductive outcomes. …”
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Intrauterine metformin exposure and adiposity outcomes in children: a systematic review and meta-analysis by George Tomlinson, Jill Hamilton, Kellie E Murphy, Jennifer Fu, Najla Tabbara, Denice S Feig

“…When stratified by maternal diagnosis, no difference in BMI was found in the diabetes and obesity subgroups, while in the polycystic ovary syndrome subgroup metformin-exposed children were heavier than non-exposed peers (SMD 0.31; 95% CI: 0, 0.62; low certainty). …”
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Evaluation of Psychological Distress in Infertile Women who Underwent ART Cycle During the COVID-19 Pandemic by Ebru Cogendez, Pinar Kumru, Sunullah Soysal, Enis Ozkaya, Belgin Devranoglu, Elif Tozkir, Ilhan Sanverdi

“…In cases of diminished ovarian reserve and oocyte freezing; a significantly higher incidence of post-traumatic stress disorder was found compared to patients with unexplained infertility, polycystic ovary syndrome, and male factor infertility (p=0.004). …”
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Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of t... by Felix C. K. Wong, Angela Z. Chan, W. S. Wong, Angel H. W. Kwan, Tracy S. M. Law, Jacqueline P. W. Chung, Jeffrey S. S. Kwok, Angel O. K. Chan

“…While a diagnosis of polycystic ovary syndrome (PCOS) with its associated metabolic disturbances was initially considered, serum total testosterone, androstenedione, and 17-hydroxyprogesterone (17-OHP) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS) were significantly increased. …”
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Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries by Yi-Ping Zhong, Ying Ying, Hai-Tao Wu, Can-Quan Zhou, Yan-Wen Xu, Qiong Wang, Jie Li, Xiao-Ting Shen, Jin Li

“…To compare the basic endocrine profile and outcomes of in vitro fertilization (IVF) in women with polycystic ovary syndrome (PCOS), ovulatory polycystic ovaries (PCO), or normal ovaries (NO). …”
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Factors influencing endometrial receptivity in women with recurrent implantation failure by Katarzyna Opuchlik, Katarzyna Pankiewicz, Piotr Pierzyński, Janusz Sierdziński, Elina Aleksejeva, Andres Salumets, Tadeusz Issat, Piotr Laudański

“…Early-receptive endometrium was diagnosed in the majority of patients with idiopathic infertility − 12 (66.7%) vs. 6 (33.3%) women (p = 0.042) and with polycystic ovary syndrome (PCOS) − 12 (70,6%) vs. 3 (17.7%) women (p = 0,0447). …”
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Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis by Lina He, Jie Lin, Zhengwen Qin, Qing Xu, Li Hao, Yanhong Fu, Xu Ran, Wei Chen

“…Conclusion LncRNA NEAT1 could promote ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis in polycystic ovary syndrome. Further investigation of this mechanism in clinical samples may have implications for understanding ovarian physiology and pathology.…”
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The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps by Aytekin Tokmak, Ebru Ersoy, Ali Özgür Ersoy, Esra Yaşar Çelik, Ali İrfan Güzel, Mustafa Uğur

“…Thirty seven women older than 40 years of age (study group), and 113 women younger than 40 years (control group) were compared in terms of various clinical and laboratory parameters including age, body mass index (BMI), gravidity, parity, abortion, basal hormone levels, tumor markers, complete blood count values, smoking status, presence of polycystic ovary syndrome (PCOS), infertility status, co-morbidities, and number and size of endometrial polyps. …”
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بررسی مقایسه‌ای سنجش تراکم استخوان در زنان مبتلا به سندرم تخمدان پلی‌کیستیک با زنان سالم by زهرا رومیانی, معصومه رضایی, بهار موئسس غفاری, نسرین صوفی زاده, محمد عزیز رسولی

“…مقاله پژوهشی مقدمه: سندرم تخمدان پلی کیستیک (Polycystic ovary syndrome) PCOS، یک اندوکرینوپاتی بسیار شایع و هتروژن است که 5 تا 18 درصد از زنان را تحت تأثیر قرار می‌دهد. …”
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