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Effect of exogenous human chorionic gonadotropin on ovulation in mice
Published 2020-01-01“…No significant differences were found in the total number of ovulated oocytes or in the number of immature (without a polar body) ovulated oocytes; nor were there differences between the groups in the number of oocytes with a developing polar body. …”
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Freezing of Oocytes and Its Effect on the Displacement of the Meiotic Spindle: Short Communication
Published 2012-01-01“…However, in 94 of these 177 oocytes (53.1%), the spindle reformed in a different position/location relative to the polar body. Our results show that after thawing and culture in half of the spindle-positive oocytes the spindle was detected in a new location, indicating that the spindle and the polar body move relative to each other.…”
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A Live Birth Subsequent to IVF following Egg Retrieval Only 12 Hours after hCG Priming
Published 2013-01-01“…The eggs were cultured in vitro and ICSI was performed following polar body extruded after 24 hours in culture. After additional 24 hours a 4-cell embryo was developed and ET was performed. …”
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Cumulus cell expansion, nuclear maturation and embryonic development of bovine cumulus-oocyte complexes matured in varying concentrations of follicular fluid.
Published 2025-01-01“…The rate of nuclear maturation as determined by the presence or absence of the first polar body was similar between control (0% FF) and treated (75% FF) groups. …”
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Biotechnological bases of the development of cloned pig embryos
Published 2019-08-01“…To perform the reconstruction, a somatic cell is placed, using micro-tools, in the perivitelline space, where the first polar body was previously located, or in the cytoplasm of an enucleated oocyte. …”
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Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti...
Published 2025-01-01“…More importantly, selective inhibition of HDAC6 by culturing TUBB8‐D417N oocytes with Tubacin or Tubastatin A showed morphologically normal spindle and drastically recovered polar‐body extrusion rate. These rescue results shed light on the strategy to treat meiotic defects in a certain group of TUBB8 mutated patients. …”
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