Timing of Wnt Inhibition Modulates Directed Differentiation of Medial Ganglionic Eminence Progenitors from Human Pluripotent Stem Cells by Ivanna Ihnatovych, Alexandra Lew, Evelyn Lazar, Anna Sheng, Timot Kellermayer, Kinga Szigeti

“…In vitro differentiation of human pluripotent stem cell into relevant cell types is a desirable model system that has the human biological context, is a renewable source, and is scalable. …”
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Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines by Nidal Ghosheh, Björn Olsson, Josefina Edsbagge, Barbara Küppers-Munther, Mariska Van Giezen, Annika Asplund, Tommy B. Andersson, Petter Björquist, Helena Carén, Stina Simonsson, Peter Sartipy, Jane Synnergren

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IL-32: A Novel Pluripotent Inflammatory Interleukin, towards Gastric Inflammation, Gastric Cancer, and Chronic Rhino Sinusitis by Muhammad Babar Khawar, Muddasir Hassan Abbasi, Nadeem Sheikh

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Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor by Toru Momozane, Eriko Fukui, Soichiro Funaki, Makoto Fujii, Yuhei Kinehara, Emiko Ito, Shigeru Miyagawa, Yuko Ohno, Yoshiki Sawa, Meinoshin Okumura, Yasushi Shintani

“…Efforts have focused on a variety of different applications for pluripotent stem cells. Several groups have reported successful methods for inducing differentiation of induced pluripotent stem cells (iPSCs) into the airway epithelium such as alveolar epithelium type II (ATII). …”
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Correction: Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. by PLOS ONE Staff

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The study of the functionality of cardiomyocytes obtained from induced pluripotent stem cells for the modeling of cardiac arrhythmias based on long QT syndrome by M. M. Slotvitsky, V. A. Tsvelaya, S. R. Frolova, E. V. Dement’eva, K. I. Agladze

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Evaluation of Retinal Pigment Epithelial Cell Cytotoxicity of Recombinant Tissue Plasminogen Activator Using Human-Induced Pluripotent Stem Cells by Hiroyuki Kamao, Atsushi Miki, Junichi Kiryu

“…The evaluation of drug-induced cytotoxicity is of great importance for the clinical application of pharmaceutical products, and human-induced pluripotent stem cells (hiPSCs) have received considerable scrutiny as a cell source for in vitro cytotoxicity testing. …”
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On the utilization of the induced pluripotent stem cell (iPSC) model to study substance use disorders: A scoping review protocol. by Wasiri Niemis, Shenita R Peterson, Chrisabella Javier, Amy Nguyen, Sanchi Subiah, Rohan H C Palmer

“…<h4>Introduction</h4>Induced pluripotent stem cells (iPSCs) are cells derived from somatic cells via reprogramming techniques. …”
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Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor by Ekta Minocha, Linan Jiang, Ashwani Kumar Gupta, Richard M. Green, Yitshak Zohar, Jason A. Wertheim

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Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma by Mayuna Nakamura, Yuka Tanaka, Keishi Hakoda, Masahiro Ohira, Tsuyoshi Kobayashi, Kenji Kurachi, Kouichi Tamura, Hideki Ohdan

“…NK cells generated from induced pluripotent stem cells (iPSCs) are a new option for use as an NK cell resource. …”
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Differentiation and Molecular Properties of Mesenchymal Stem Cells Derived from Murine Induced Pluripotent Stem Cells Derived on Gelatin or Collagen by Chizuka Obara, Kazuya Takizawa, Kenichi Tomiyama, Masaharu Hazawa, Ai Saotome-Nakamura, Takaya Gotoh, Takeshi Yasuda, Katsushi Tajima

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Generation of Human-Induced Pluripotent Stem Cells by a Nonintegrating RNA Sendai Virus Vector in Feeder-Free or Xeno-Free Conditions by Chad C. MacArthur, Andrew Fontes, Namritha Ravinder, David Kuninger, Jasmeet Kaur, Matthew Bailey, Antje Taliana, Mohan C. Vemuri, Pauline T. Lieu

“…The generation of induced pluripotent stem cells (iPSCs) from somatic cells has enabled the possibility of providing unprecedented access to patient-specific iPSC cells for drug screening, disease modeling, and cell therapy applications. …”
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Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System by Fernanda C. Paccola Mesquita, Camila Hochman-Mendez, Jacquelynn Morrissey, Luiz C. Sampaio, Doris A. Taylor

“…Until the emergence of induced pluripotent stem cells (iPSCs), autologous cell sources of this magnitude and with the required complexity were not available. …”
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Induced Pluripotent Stem Cell Derivation and Ex Vivo Gene Correction Using a Mucopolysaccharidosis Type 1 Disease Mouse Model by Toshio Miki, Ludivina Vazquez, Lisa Yanuaria, Omar Lopez, Irving M. Garcia, Kazuo Ohashi, Natalie S. Rodriguez

“…Here, we demonstrate the proof of concept of ex vivo gene editing therapy using induced pluripotent stem cell (iPSC) and CRISPR/Cas9 technologies with MPS-1 model mouse cell. …”
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Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures by Jun Liu, Claire A. Higgins, Jenna C. Whitehouse, Susan J. Harris, Heather Crawford, Angela M. Christiano, Majlinda Lako, Nicholas Hole, Colin A. B. Jahoda

“…In view of their regulatory properties, in this study, we investigated the interaction between hair follicle dermal cells (DP and DS) and embryonic stem cells (ESCs); induced pluripotent stem cells (iPSCs); and haematopoietic stem cells. …”
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The use of artificial intelligence in induced pluripotent stem cell-based technology over 10-year period: A systematic scoping review. by Quan Duy Vo, Yukihiro Saito, Toshihiro Ida, Kazufumi Nakamura, Shinsuke Yuasa

“…<h4>Background</h4>Stem cell research, particularly in the domain of induced pluripotent stem cell (iPSC) technology, has shown significant progress. …”
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A Pilot Study Investigating the Expression Levels of Pluripotency-Associated Genes in Rectal Swab Samples for Colorectal Polyp and Cancer Diagnosis and Prognosis by Ryan Wai-Yan Sin, Dominic Chi-Chung Foo, Deepak Narayanan Iyer, May Sau-Yee Fan, Xue Li, Oswens Siu-Hung Lo, Wai-Lun Law, Lui Ng

“…Expression levels of 15 pluripotency-associated genes were assessed by quantitative PCR in 53 rectal swab specimens referred for endoscopic screening. …”
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Enhanced Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood and Using Their Mesoderm Differentiation Ability to Regenerate Infarcted Myocardium by Ju-Young Kim, Han-Mo Yang, Joo-Eun Lee, Mika Jeon, Sang-Bum Bang, Jihye You, Joonoh Kim, Jaewon Lee, Jin Hur, Hyo-Soo Kim

“…Тhe most pressing issue in generating induced pluripotent stem cells (iPSCs) in clinical practice is the cell source. …”
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Are Mesenchymal Cells Indeed Pluripotent Stem Cells or Just Stromal Cells? OCT-4 and VSELs Biology Has Led to Better Understanding by Deepa Bhartiya

“…However, which stem cells will be the best candidate for regenerative medicine remains an enigma. Compared to pluripotent stem cells with associated risks of immune rejection and teratoma formation, adult stem cells especially the mesenchymal stem cells (MSCs) are hyped to be a suitable alternate since they also exhibit pluripotent properties. …”
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Cylindroma Mimicking Neurofibroma by Vinod Kumar Gonuru, Sridhar Reddy Dandala, M.S.S. Samhita, Ashok Kumar

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