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3761
Clinical advances in kidney autotransplantation: a review
Published 2025-02-01“…These techniques have shown promising outcomes, and robotic platforms have the potential to further reduce complications. …”
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3762
Exploring anti-cancer activities of epidermal growth factor-immobilized polymeric nanoparticles
Published 2025-02-01“…These results suggest that the unique anti-cancer effects of EGF nanoparticles are not dependent on the carrier platform. Furthermore, EGF nanoparticles exhibited high cytotoxicity against cancer cells responding poorly to conventional EGFR-targeted anti-cancer drugs, showing potential for future medical applications.…”
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3763
Sensitivity of global solar irradiance to transposition models: Assessing risks associated with model discrepancies
Published 2025-03-01“…To evaluate and validate the proposed theory, eight commonly used TMs from literature, database platforms and software were chosen and tested on 133 sites with various climatic and geographical conditions in the Northern Hemisphere. …”
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3764
Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells
Published 2012-01-01“…We separated breast cancer cell nuclei from cytoplasm, and identified small RNA sequences using a high-throughput sequencing platform. To determine the relationship between miRNA sub-cellular distribution and cancer progression, we used microarray analysis to examine the miRNA expression levels in nucleus and cytoplasm of three human cell lines, one normal breast cell line and two breast cancer cell lines. …”
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3765
Modeling the digital transformation of industrial holdings
Published 2024-05-01“…As part of the methodological implementation of the proposed methodology, an instrumental approach is considered that allows to systematize the tools of digital transformation of industrial systems in the context of digital business models, digital technologies and platform solutions, as well as to argue the key features of each of the tools. …”
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3766
Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation
Published 2024-12-01“…Compared to traditional methods, our proposed strategy enables high-throughput production of size-controlled spheroids with excellent shape retention, while enhanced gas exchange during culture improves differentiation marker expression. This platform provides an efficient and cost-effective solution for biosensing applications, such as drug screening, disease modeling, and personalized therapy monitoring. …”
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3767
Demonstration of Participation Networks in Urban Transport Policy of Public and Private Sectors through Social Media: The Case of Bike-Sharing Pricing Strategy in China
Published 2021-01-01“…Social media has become a valuable platform that enables public and private stakeholders to participate and interact in various transport policies. …”
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3768
Efficacy and safety of high-voltage versus standard-voltage pulsed radiofrequency ablation for patients with neuropathic pain: protocol for a systematic review and meta-analysis
Published 2022-07-01“…This study aims to compare the efficacy and safety of high-voltage PRF ablation and standard-voltage PRF ablation for the treatment of patients with NP.Methods and analysis We will search PubMed/MEDLINE, EMBASE, Web of Science, the Cochrane Library, conference proceedings for relevant abstracts, clinical trials registers (ClinicalTrials.gov) and the WHO’s International Clinical Trial Registry Platform (from the date of inception until 15 March 2022). …”
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3769
Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines
Published 2025-01-01“…Currently, there are no approved therapeutic HPV vaccines worldwide; however, active progress is being made in clinical research and development using multiple platforms such as peptides, proteins, DNA, RNA, bacterial vectors, viral vectors, and cell-based, each offering relative advantages and limitations for delivering HPV antigens and generating targeted immune responses. …”
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3770
E-cigarettes on Instagram: Exploring vape content via an Australian vaping influencer
Published 2024-01-01“…Greater regulation and/or stronger enforcement of e-cigarette content on social media platforms such as Instagram is necessary to prevent the ongoing promotion of these harmful products.…”
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3771
A comprehensive global mapping of offshore lighting
Published 2025-02-01“…A wide range of lighting structures is present, i.e., fishing grounds, platforms, anchorages, gas flares, transit routes, and the glow surrounding bright lighting onshore. …”
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3772
On the ability to extract MLVA profiles of Vibrio cholerae isolates from WGS data generated with Oxford Nanopore Technologies
Published 2025-01-01“…In this study, the MLVAType application was validated using long reads generated by Oxford Nanopore Technologies (ONT) sequencing platforms. In silico MLVA profiles of V. cholerae isolates (n = 9) from the Democratic Republic of the Congo were generated using the MLVAType application on Nanopore WGS data. …”
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3773
Genomic and phylogenetic analysis of a NDM-1 producing ST152 Klebsiella pneumoniae isolated from a bloodstream infection in China
Published 2025-01-01“…Whole-genome sequencing was conducted using the Illumina HiSeq and Oxford Nanopore GridION X5 platforms, and the genomic features were analyzed using a range of bioinformatics tools. …”
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3774
Association between atherogenic index of plasma and type 2 diabetic complications: a cross-sectional study
Published 2025-02-01“…Consequently, this study investigates the potential association between AIP and type 2 diabetic complications through a cross-sectional design.MethodsThe National Metabolic Management Center(MMC) serves as a comprehensive platform dedicated to the establishment of standardized protocols for the diagnosis, treatment, and long-term follow-up of metabolic diseases. …”
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3775
A Survey of Data Partitioning and Sampling Methods to Support Big Data Analysis
Published 2020-06-01“…Computer clusters with the shared-nothing architecture are the major computing platforms for big data processing and analysis. In cluster computing, data partitioning and sampling are two fundamental strategies to speed up the computation of big data and increase scalability. …”
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3776
The anti-cancerous mechanism of licochalcone A on human hepatoma cell HepG2 based on the miRNA omics
Published 2023-07-01“…A protein-protein interaction network was structured on the STRING platform to discover the hub genes. Among them, PIK3R1, CDC42, ESR1, SMAD4, SUMO1, KRAS, AGO1, etc. were screened out. …”
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3777
ZooCNN: A Zero-Order Optimized Convolutional Neural Network for Pneumonia Classification Using Chest Radiographs
Published 2025-01-01“…Conventional CNN models, though promising, face challenges such as overfitting and have high computational costs. The use of ZooPlatform (ZooPT), a hyperparameter finetuning strategy, on a baseline CNN model finetunes the hyperparameters and provides a modified architecture, ZooCNN, with a 72% reduction in weights. …”
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3778
Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC
Published 2019-03-01“…A prospective study was performed to detect differences in genetic profiles of cfDNA in sputum, plasma, urine, and tumor tissue from 50 advanced NSCLC patients in parallel by the same next‐generation sequencing (NGS) platform. Driver genes alterations were identified in cfDNA sample and matched tumor sample, with an overall concordance rate of 86% in plasma cfDNA, 74% in sputum cfDNA, 70% in urine cfDNA, and 90% in cfDNA of combination of plasma, sputum, and urine. …”
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3779
Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma
Published 2025-02-01“…Nonetheless, they are of particular interest for the treatment of glioblastoma, which is an aggressive form of brain cancer with few effective therapeutic options, due to their ability to cross the highly selective blood-brain barrier.Methods Here, we use our pooled screening platform, CARPOOL, to expedite the discovery of CARs with antitumor functions necessary for solid tumor efficacy. …”
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3780
A realistic human head phantom for electromagnetic detection of brain diseases
Published 2025-01-01“…It proved valuable for studying the distribution of electromagnetic fields in the human head and for investigating novel electromagnetic detection techniques exploiting brain tissue dielectric properties. (4) The created physical model and the numerical model were derived from the same person, which provided a good continuity between simulation experiments and physical experiments, and provided a realistic verification platform for the research of electromagnetic detection technology for brain diseases, such as differentiating the kind of stroke, monitoring brain edema, brain tumor microwave imaging, and diagnosis of Alzheimer’s disease.…”
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