Nurses' Sleep Quality and Its Influencing Factors During the First Explosive COVID‐19 Outbreak in Zhejiang, China, After the Relaxation of Epidemic Prevention and Control Measures:... by Lifen Lu, Di Sheng, Yaling Zhu, Xiaowei Xia, Guanghui Chen, Jiali Liang, Xiulan Shen, Gui Zheng

“…The participants were recruited using convenience sampling, and the survey was distributed via the WeChat platform. The survey included a general information form; the Self‐Rating Scale of Sleep (SRSS); the Depression, Anxiety, and Stress Scale‐21 (DASS‐21); the Perceived Social Support Scale (PSSS); and the Brief Resilience Scale (BRS). …”
Get full text

BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Importantly, mice receiving BCG vaccination followed by BAFF or APRIL immunotherapy exhibited superior long-term protection against pulmonary tuberculosis relative to controls that received only BCG.ConclusionIn summary, our findings demonstrate that combining BCG vaccination with B cell targeted immunomodulatory therapies can improve long-term protection against pulmonary tuberculosis, highlighting the continued relevance and underutilized potential of BCG as a vaccine platform.…”
Get full text

Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting by Salvador Figuereo, Sahra Isse Mohamed, Desalegn Takele, Abdulrahman M. Sheikh, Solomon Chane Abera, Ayni Muhiadin Mohamed, Mutaawe Lubogo, Hassan Mukhtar Abukar, Mary Joan Karanja, Sulaiman Bangura, Antoine Abou Fayad, Ali Haji Adam, Abdinasir Yusuf Osman, Sk Md Mamunur Rahman Malik

“…At the same time, other innovative solutions were used for testing, such as repurposing tuberculosis GeneXpert diagnostic platforms to increase access to testing at points-of-care and introducing antigen rapid diagnostic tests for hard-to-reach communities. …”
Get full text

A persona-based exploration of rabies post-exposure prophylaxis seeking behavior and its implication for communication strategic planning: Evidence from Thailand by Jitjayang Yamabhai, Patoo Cusripituck, Teerawan Mingbualuang, Nareerat Sangkachai, Wimwiga Sakchainanon, Chanatda Tungwongjulaniam, Onphirul Yurachai, Ratana Theerawat, Anuwat Wiratsudakul

“…Notably, nearly half (44.74 %; 17/38) of the individuals involved in the study indicated utilizing interpersonal communication, followed by digital platforms (42.11 %; 16/38) and traditional communication channels (10.52 %; 5/38). …”
Get full text

Percutaneous nephroscopy versus flexible ureteroscopy in the treatment of calyceal diverticulum calculi: a meta-analysis by Conglei Hu, Rui Ma, Yongxiang Shao, Zilong Liang, Meng Cheng, Haofeng Pang, Liping Yao, Fei Liu

“…Methods We searched Pubmed, Cochrane Library, Web of Science, Embase, Clinical trial platform, CNKI, VIP until April 2024. We utilized the Newcastle–Ottawa Scale (NOS, 0 to 9 stars) to assess the quality of the included literature. …”
Get full text

Enhancing the Therapeutic Effect and Bioavailability of Irradiated Silver Nanoparticle-Capped Chitosan-Coated Rosuvastatin Calcium Nanovesicles for the Treatment of Liver Cancer by Tamer Mohamed Mahmoud, Mohamed Mahmoud Abdelfatah, Mahmoud Mohamed Omar, Omiya Ali Hasan, Saad M. Wali, Mohamed S. El-Mofty, Mohamed G. Ewees, Amel E. Salem, Tarek I. Abd-El-Galil, Dina Mohamed Mahmoud

“…The authors could propose that novel INop could serve as an advanced platform to improve oral bioavailability and enhance hepatic carcinoma recovery.…”
Get full text

Microbiome of <i>Hyalomma dromedarii</i> (Ixodida: Ixodidae) Ticks: Variation in Community Structure with Regard to Sex and Host Habitat by Nighat Perveen, Alejandro Cabezas-Cruz, Daniil Iliashevich, Lianet Abuin-Denis, Olivier Andre Sparagano, Arve Lee Willingham

“…A total of 40 ticks (male (15), female (15), and nymph (10)) were selected from tick samples collected from camels and processed for genomic DNA and next-generation sequencing using the Illumina MiSeq platform. We obtained 151,168 read counts, and these formed 237 operational taxonomic units representing 11 phyla, 22 classes, 77 families, and 164 genera. …”
Get full text

Galaxy @Sciensano: a comprehensive bioinformatics portal for genomics-based microbial typing, characterization, and outbreak detection by Bert Bogaerts, Julien Van Braekel, Alexander Van Uffelen, Jolien D’aes, Maxime Godfroid, Thomas Delcourt, Michael Kelchtermans, Kato Milis, Nathalie Goeders, Sigrid C. J. De Keersmaecker, Nancy H. C. Roosens, Raf Winand, Kevin Vanneste

“…At Sciensano, the Belgian national public health institute, an intuitive and user-friendly bioinformatics tool portal was implemented using Galaxy, an open-source platform for data analysis and workflow creation. The Galaxy @Sciensano instance is available to both internal and external scientists and offers a wide range of tools provided by the community, complemented by over 50 custom tools and pipelines developed in-house. …”
Get full text

The Effect of Whole-Body Vibration on Upper Extremity Function in Children with Cerebral Palsy: A Pilot Study by Marianna Kelaiditi, Alexandra Lepoura, Anna Christakou, Nikolaos Chrysagis, Vasiliki Sakellari

“…This pilot study assessed the feasibility and preliminary efficacy of Upper Extremity Vibration Therapy using a Whole-Body Vibration Platform (UEVT-WBV) combined with conventional physiotherapy, in enhancing upper extremity function and reducing spasticity in children with CP. …”
Get full text

Mutation Analysis of Synthetic DNA Barcodes in a Fission Yeast Gene Deletion Library by Sanger Sequencing by Minho Lee, Shin-Jung Choi, Sangjo Han, Miyoung Nam, Dongsup Kim, Dong-Uk Kim, Kwang-Lae Hoe

“…Together, well-defined barcode sequences, combined with the next-generation sequencing platform, promise to make the fission yeast gene deletion library a powerful tool for understanding gene function.…”
Get full text

Individual participant data meta-analysis of trials comparing frozen versus fresh embryo transfer strategy (INFORM): a protocol by Lan N Vuong, Rui Wang, Ben W Mol, Rong Li, Karin Hammarberg, Kate Brian, Yun Sun, Pollyanna Hardy, Anja Pinborg, Siladitya Bhattacharya, Sacha Stormlund, David J McLernon, Zi-Jiang Chen, Richard S Legro, Carlos Simon, Shimona Lai, Marian G Showell, Daimin Wei, Ze Wang, Keliang Wu, Xavier Santamaría, Christophe Blockeel, Femke Mol, Anna P Ferraretti, Bruce S Shapiro, Forest C Garner, Christos A Venetis, Abha Maheshwari, Gwenda Burns

“…Therefore, we plan a systematic review and individual participant data meta-analysis of RCTs comparing a freeze-all and a fresh transfer policy.Methods and analysis We will search electronic databases (Medline, Embase, PsycINFO and CENTRAL) and trial registries (ClinicalTrials.gov and the International Clinical Trials Registry Platform) from their inception to present to identify eligible RCTs. …”
Get full text

The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity by Chiara Pesenti, Stefania Elena Navone, Laura Guarnaccia, Andrea Terrasi, Jole Costanza, Rosamaria Silipigni, Silvana Guarneri, Nicola Fusco, Laura Fontana, Marco Locatelli, Paolo Rampini, Rolando Campanella, Silvia Tabano, Monica Miozzo, Giovanni Marfia

“…Here, using array-CGH platform, we investigated genetic and genomic aberration profiles of GBM parent tumour (n=10) and their primarily derived GSCs. …”
Get full text

Deriving and validating a risk prediction model for long COVID-19: protocol for an observational cohort study using linked Scottish data by Jennifer K Quint, Aziz Sheikh, Chris Robertson, Srinivasa Vittal Katikireddi, Emily Moore, Colin R Simpson, Luke Daines, Eleftheria Vasileiou, Syed Ahmar Shah, Rachel H Mulholland, Vicky Hammersley, Steven Kerr, Ting Shi, David Weatherill, Elisa Pesenti

“…In this protocol, we describe plans to develop a prediction model to identify individuals at risk of developing long-COVID.Methods and analysis We will use the national Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II) platform, a population-level linked dataset of routine electronic healthcare data from 5.4 million individuals in Scotland. …”
Get full text

可穿戴设备在卒中风险预测及卒中后管理中的应用进展 Research Progress on the Application of Wearable Devices in Stroke Risk Prediction and Post-Stroke Management... by 吴雅婷1，魏宸铭1，桑振华1，陈乐1，梁怡凡1，武剑1，2，3 (WU Yating1, WEI Chenming1, SANG Zhenhua1, CHEN Le1, LIANG Yifan1, WU Jian1,2,3)

“…By integrating with health management platforms and artificial intelligence algorithms, wearable devices can significantly enhance the accuracy of risk assessment, optimize rehabilitation treatment plans, and thus improve the patients’ outcomes. …”
Get full text

Mapping Chilean clinical research: a protocol for a scoping review and multiple evidence gap maps by Sergio R Muñoz, Nicolás Meza, Eva Madrid, Juan Victor Ariel Franco, Gerard Urrútia, Camila Micaela Escobar Liquitay, Javier Bracchiglione

“…We will aim to disseminate our findings through different academic platforms, social media, local press, among others. …”
Get full text

High-resolution awake mouse fMRI at 14 tesla by David Hike, Xiaochen Liu, Zeping Xie, Bei Zhang, Sangcheon Choi, Xiaoqing Alice Zhou, Andy Liu, Alyssa Murstein, Yuanyuan Jiang, Anna Devor, Xin Yu

“…This work establishes a high-resolution awake mouse fMRI platform, enabling brain-wide functional mapping of sensory signal processing in higher association cortical areas.…”
Get full text

Quinoid to benzenoid transition-driven glutathione sensing: Dual-emission carbon dots and smartphone-based ratiometric fluorescence analysis by Al-Montaser Bellah H. Ali, Ashraf M. Mahmoud, Yousef A. Bin Jardan, Aya M. Mostafa, James Barker, Mohamed M. El-Wekil

“…The method's versatility was enhanced through the development of a dual-mode smartphone platform, enabling both colorimetric and fluorometric GSH detection. …”
Get full text

Pre-operative DNA methylation marks as predictors of weight loss outcomes after sleeve gastrectomy by Guillermo Paz-López, Teresa M. Linares-Pineda, Andrés González-Jiménez, Raquel Sancho-Marín, Luis Ocaña-Wilhelmi, Francisco J. Tinahones, Sonsoles Morcillo, Carolina Gutiérrez-Repiso

“…Blood DNA methylation was analyzed prior to surgery using the Infinium Methylation EPIC Bead Chip array-based platform. Results: A total number of 76,559 differentially methylated positions (DMPs) (p < 0.05) were found between <60% EWL and >60% EWL groups. …”
Get full text

Influences of Different Drop Height Training on Lower Extremity Kinematics and Stiffness during Repetitive Drop Jump by I-Lin Wang, Yi-Ming Chen, Ke-Ke Zhang, Yu-Ge Li, Yu Su, Chou Wu, Chun-Sheng Ho

“…The 1st, 50th, 100th, 150th, and 200th DJs (DJ1, DJs50, DJs100, DJs150, and DJs200) were recorded by using a BTS motion capture system and force platform. The MATLAB software was used to compare the kinematic and stiffness data of DJ1, DJs50, DJs100, DJs150, and DJs200 with one-way ANOVA repeated measure. …”
Get full text

Automatic Characterization of Prostate Suspect Lesions on T2-Weighted Image Acquisitions Using Texture Features and Machine-Learning Methods: A Pilot Study by Teodora Telecan, Cosmin Caraiani, Bianca Boca, Roxana Sipos-Lascu, Laura Diosan, Zoltan Balint, Raluca Maria Hendea, Iulia Andras, Nicolae Crisan, Monica Lupsor-Platon

“…Each nodule was manually segmented using the open-source 3D Slicer platform, and textural features were extracted using the PyRadiomics (version 3.0.1) library. …”
Get full text