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Influence of flavonoids’ lipophilicity on platelet aggregation
Published 2019-12-01“…Previously, it has been reported that all tested flavonoids exhibit an antiaggregatory effect on platelet aggregation when measured by impedance aggregometry on whole blood, in the test of aggregation induced by adenosine diphosphate (ADP). …”
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The effect of different strains of Helicobacter pylori on platelet aggregation
Published 2007-01-01“…The mechanisms by which certain strains of H pylori induce platelet aggregation through interactions with platelet glycoprotein Ib have been previously described.…”
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PATHOGENETIC ROLE OF THROMBOCYTES IN THE DEVELOPMENT OF AUTOIMMUNE PATHOLOGY OF THE THYROID GLAND
Published 2018-12-01Subjects: “…platelet aggregation, antimicrosomal antibodies, thyroid gland…”
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Antithrombotic activity of flavonoids and polyphenols rich plant species
Published 2019-12-01Subjects: “…platelet aggregation…”
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The Effect of the Thai Herbal Suksaiyad Formula on Platelet Aggregation in Healthy Volunteers: A Quasi-experimental, Single-dose Study
Published 2025-02-01Subjects: Get full text
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Effect of antithrombotic therapies on small bowel bleeding: an European multicenter retrospective study
Published 2025-01-01Subjects: Get full text
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The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study
Published 2025-02-01Subjects: Get full text
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Bioanalytical method development, in-vivo pharmacokinetic evaluation, ex-vivo platelet aggregation inhibition activity of a novel solid dispersion formulation of ticagrelor
Published 2025-02-01“…Additionally, our study successfully enhanced Ticagrelor's oral bioavailability, and the developed formulation has more significant inhibition of ADP-induced platelet aggregation relative to the marketed formulation, indicating its substantial therapeutic potential.…”
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Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor
Published 2025-01-01Subjects: Get full text
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Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects
Published 2025-02-01“…Results: All Leea indica extracts and the 70 % ethanolic Vitex trifolia extract significantly inhibited platelet aggregation. Clausena lansium extracts promoted platelet aggregation. …”
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A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk
Published 2024-04-01Subjects: Get full text
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Advancing Platelet Research Through Live-Cell Imaging: Challenges, Techniques, and Insights
Published 2025-01-01Subjects: Get full text
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Comprehensive characterization of platelet function in dogs with hyperadrenocorticism
Published 2025-02-01“…Various platelet functional responses including platelet aggregation and dense-granule secretion were evaluated. 2-MeSADP- and low concentration of thrombin-induced platelet aggregation and secretion were significantly inhibited in dogs with HAC compared to normal dogs. …”
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Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel
Published 2025-02-01“…Further, %inhibition of platelet aggregation from AT-10 treatment in poor metaboliser group was significantly higher than the clopidogrel treatments in extensive metaboliser group.Overall pharmacokinetic comparison in all subjects indicates that AT-10 gives greater exposure to active Metabolite H4 than clopidogrel.Conclusion AT-10 showed better inhibition of platelet aggregation in poor metabolizers as compared to Clopidogrel. …”
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Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation
Published 2018-01-01“…Neither the adenylate cyclase inhibitor SQ22536 nor the guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one significantly reversed the Ir-6-mediated inhibition of collagen-induced platelet aggregation. Moreover, Ir-6 did not considerably diminish OH radical signals in collagen-activated platelets or Fenton reaction solution. …”
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Wound Management Property of a Hydroethanolic Leaf Extract of Cnestis ferruginea DC
Published 2021-01-01“…CFHE (1.6–100 mg/ml) promoted platelet aggregation (p≤0.0001) by 37–67% (IC50: 3.1–6.2 mg/ml). …”
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Impact of inflammation on recurrent gastroduodenal ulcer bleeding
Published 2018-08-01“…Effect of leukocytes on platelet aggregation induced by collagen and adenosinediphosphate was estimated in vitro. …”
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Understanding the Activation of Platelets in Diabetes and Its Modulation by Allyl Methyl Sulfide, an Active Metabolite of Garlic
Published 2021-01-01“…We observed an inhibitory effect of allyl methyl sulfide on platelet aggregation, platelet activation, platelet macrophage interaction, and increased ROS levels in type 1 diabetes. …”
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The Impact of Anti-Diabetics on Platelets Function and Cardiovascular Outcomes in Type 2 Diabetes Mellitus: A Narrative Review
Published 2025-01-01“…We realized various mechanisms responsible for enhanced platelet aggregation in T2DM, represented by immature, large, or activated platelets in the altered metabolic environment, against the background of vascular damage in DM. …”
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Evaluation of the effect of 48 weeks of BIC/F/TAF and DRV/c/F/TAF on platelet function in the context of rapid ART start
Published 2025-12-01“…Platelet activation was assessed by real-time flow cytometry to examine integrin activation and granule release and platelet aggregation was evaluated by light transmission aggregometry. …”
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