Characterization of cerebro-vascular disease in the Intermediate Care Unit. Multicentre study in the central part of Cuba. by Alba Enseñat Alvarez, Rubén Bembibre Taboada, Maribel Misas Menéndez, Julio Cortizo Hernández, Niurka Galende Hernández, Aleida Hernández Lara, Ramón Erice Lafont

“…The isquemic cerebrovascular desease was the most frequent reported with 86,7 % and anti-aggregate platelets was the medication most frequently used (77,5 %) In regards to the location of the lesion 51,1 % were reported in the parietal region and the predominant diagnosis was the atherothrombotic infarct ( 59,9 %). …”
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Identification of Fe-bearing phases in the as-cast microstructure of AA6026 alloy and their evolution during homogenization treatment by Radetić T., Popović M., Novaković M., Rajić V., Romhanji E.

“…The EDS microanalysis and electron diffraction showed that one set of platelets represented thin sections of α-Al(Fe,Mn)Si microconstituent. …”
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HMGB-1 as a Novel Predictor of Disease Severity and Prognosis in Patients with Hemorrhagic Fever with Renal Syndrome by Hong Du, Jing Li, Haitao Yu, Jianqi Lian, Ye Zhang, Ying Zhang, Xuefan Bai, Pingzhong Wang

“…The levels of white blood cells (WBC), platelets (PLT), hematocrit (HCT), albumin (ALB), blood urea nitrogen (BUN), serum creatinine (Scr), and uric acid (UA) were routinely tested in the same time frame. …”
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Correction of Thrombocytopenia before Elective Surgery / Invasive Procedures in Patients with Liver Cirrhosis (Experts’ Agreement) by M. V. Maevskaya, M. Yu. Nadinskaia, E. N. Bessonova, N. I. Geyvandova, M. S. Zharkova, E. A. Kitsenko, N. V. Korochanskaya, I. A. Kurkina, A. L. Melikyan, V. G. Morozov, Yu. V. Khoronko, T. A. Deeva, K. A. Gulyaeva, V. T. Ivashkin

“…As a result of portal hypertension (sequestration of platelets in an enlarged spleen) and liver failure (decreased production of thrombopoietin in the liver) in liver cirrhosis, thrombocytopenia develops, which is associated with the risk of periprocedural/perioperative bleeding complications. …”
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Point of Care Perioperative Coagulation Management in Liver Transplantation and Complete Portal Vein Thrombosis by Cristiano Piangatelli, Lucia Faloia, Claudia Cristiani, Ilaria Valentini, Marco Vivarelli

“…Based on ROTEM findings, the patient received 16 g of human fibrinogen concentrate, half preoperatively (with prothrombin complex concentrate 2000 IU, tranexamic acid 1 g, and platelets 2 IU), and two doses of 4 g before and after graft reperfusion; we achieved normalization of all monitored parameters. …”
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Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes by J. R. Thiele, J. Zeller, H. Bannasch, G. B. Stark, K. Peter, S. U. Eisenhardt

“…Recently, a dissociation mechanism of pCRP has been identified on activated platelets and activated/apoptotic cells associated with the amplification of the proinflammatory potential. …”
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The Effect of Clopidogrel and Ticagrelor on Human Adipose Mesenchymal Stem Cell Osteogenic Differentiation Potential: In Vitro Comparative Study by Sally S. Mohamed, Hala F. Zaki, Shereen N. Raafat

“…Ticagrelor (TICA) and clopidogrel (CLP) are extensively used antiplatelet drugs that act by antagonizing the P2Y12 receptors that are found on platelets in addition to bone cells. Aim. The purpose of this study was to investigate the effect of clopidogrel and ticagrelor on stem cells osteogenic differentiation in vitro. …”
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The Effect of Cell Salvage on Bleeding and Transfusion Needs in Cardiac Surgery by Frixos Tachias, Evangelia Samara, Anastasios Petrou, Agathi Karakosta, Stavros Siminelakis, Efstratios Apostolakis, Petros Tzimas

“…Both groups had almost identical bleeding and transfusion rates (median value: 2 units of red blood cells (RBC) and no units of fresh frozen plasma (FFP) and platelets (PLT) for both groups, p>0.05). Patients in the cell-salvage group presented slightly higher hemoglobin concentrations (10.6 ± 1.1 vs. 10.1 ± 1.7 g/dL, p<0.05, respectively) and a tendency towards better oxygenation indices (PaO2/FiO2: 241 ± 94 vs. 207 ± 84, p=0.013) in the postoperative period albeit with a tendency for prolongation of prothrombin time (INR: 1.31 ± 0.18 vs. 1.26 ± 0.12, p=0.008). …”
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Thromboelastometry Identified Alteration of Clot Stabilization and Factor XIII Supplementation Need in a Patient with Decompensated Liver Disease Undergoing Liver Biopsy by Tomaz Crochemore, Felicio Aragão Savioli

“…The laboratory tests revealed platelets of 142x103/mm3, plasma fibrinogen concentration of 221 mg/dl, increased international nationalized ratio (INR 1.9), total bilirubin of 3.9mg/dl, direct bilirubin of 2.3mg/dl, ALT 751U/l, and AST 540U/l without acute bleeding. …”
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A Pooling Genome-Wide Association Study Identifies Susceptibility Loci and Signaling Pathways of Immune Thrombocytopenia in Chinese Han Population by Yanmei Xu, Jing Li, Wentao Yang, Xiaoli Tang, Bo Huang, Jing Liu, Jin Lin, Jing Zhang, Weiming Yang, Shuqi Li, Fan Sun, Libin Deng, Xiaozhong Wang

“…Immune thrombocytopenia (ITP) is an acquired bleeding disease due to immune-mediated destruction of antilogous platelets and ineffective thrombopoiesis. Although the etiology of ITP remains unknown, genetic variants are thought to predispose individuals to the disease. …”
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Alterations of Hematologic and Hematopoietic Parameters in Mice Exposed to Pulsed Electromagnetic Field by Kangchu Li, Zenghui Teng, Zhaohui Liu, Yuxing Zhang, Kaiping Long, Qimei Liao, Ansheng Ni, Guirong Ding, Shirong Ma

“…Red blood cells (RBC), hemoglobin (HGB), and platelets (PLT) were not changed in all exposed groups. …”
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Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping by Hannah L. Cornman, Martin P. Alphonse, Arbor Dykema, Alexander L. Kollhoff, Kevin K. Lee, Jaya Manjunath, Emily Z Ma, Varsha Parthasarathy, Junwen Deng, Thomas Pritchard, Anusha Kambala, Melika Marani, Kayla A. Parr, Javid P. Mohammed, Madan M. Kwatra, Jay H. Bream, Won Jin Ho, Shawn G. Kwatra

“…We found that the index patient had a novel form of erythroderma characterized by increased interleukin (IL)-13- and IL-17-producing γVδ2 T cells, basophils, and activated platelets. Whole-genome sequencing of PBMCs and immunofluorescence staining of skin biopsies revealed increased expression of Th2- (IL-13, IL-4Rα) and Th17-associated markers (IL-17, IL-17Rα) and non-functional mutations associated with Th2 and Th17 signaling, demonstrating that PBMCs can reflect cutaneous disease pathology. …”
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The Novel Methods for Analysis of Exosomes Released from Endothelial Cells and Endothelial Progenitor Cells by Jinju Wang, Runmin Guo, Yi Yang, Bradley Jacobs, Suhong Chen, Ifeanyi Iwuchukwu, Kenneth J. Gaines, Yanfang Chen, Richard Simman, Guiyuan Lv, Keng Wu, Ji C. Bihl

“…The sensitivity and specificity were determined by using positive and negative markers for EXs (CD63), platelets (CD41), erythrocytes (CD235a), and microvesicles (Annexin V). …”
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Aloe vera: A promising natural herbal supplement for enhancing growth, physiology, antioxidant activity and immunity in Catla catla by Zeeshan Yousaf, Syed Makhdoom Hussain, Shafaqat Ali, Dariusz Kucharczyk, Joanna Nowosad, Konrad Turkowski, Bilal Ahamad Paray, Adan Naeem

“…Hematological analysis revealed significant differences (p < 0.05) in white blood cells, red blood cells, platelets, and hemoglobin levels in fish fed at 3 % A. vera diet. …”
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Outcomes of Severe Sepsis and Septic Shock Patients on Chronic Antiplatelet Treatment: A Historical Cohort Study by Juan C. Valerio-Rojas, Insara J. Jaffer, Daryl J. Kor, Ognjen Gajic, Rodrigo Cartin-Ceba

“…Sepsis is characterized by dysfunctional activation of platelets, and antiplatelet therapy could improve the outcomes of septic patients. …”
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Endothelial protease-activated receptor 4: impotent or important? by Rahul Rajala, Rahul Rajala, Rahul Rajala, Courtney T. Griffin, Courtney T. Griffin

“…Several studies have demonstrated a lack of functionality for PAR4 in ECs, with many claiming that PAR4 function is confined mostly to platelets. A recent study from our lab identified low expressing but functional PAR4 in hepatic ECs in vivo. …”
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Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage by Yazhao Zhang, Yanan Tian, Jianhui Wei, Yi Xiang

“…Interleukin-12 (IL-12) promotes brain inflammation, and regulates coagulation mediated by red blood cells and platelets. This study was designed to investigate the relationship of serum IL-12 to inflammation, hematoma volume, and prognosis in ICH patients. …”
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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. by Deirdre Larkin, Bas de Laat, P Vince Jenkins, James Bunn, Alister G Craig, Virginie Terraube, Roger J S Preston, Cynthia Donkor, George E Grau, Jan A van Mourik, James S O'Donnell

“…Plasmodium falciparum infection results in adhesion of infected erythrocytes to blood vessel endothelium, and acute endothelial cell activation, together with sequestration of platelets and leucocytes. We have previously shown that patients with severe infection or fulminant cerebral malaria have significantly increased circulatory levels of the adhesive glycoprotein von Willebrand factor (VWF) and its propeptide, both of which are indices of endothelial cell activation. …”
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Lamellar Body Count With Cell Dyn Emerald And Cell Dyn Ruby Methods On Preterm Birth by Erlinda Widyastuti, Ario Imandiri

“…Lamellar bodies are present in amniotic fluid in increasing quantities as gestation advances, 1 – 5 µm in size, similar in size to small platelets and can be counted on most electronic cell counters in hematology analyzer. …”
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Measurement of Several Hematological and Serological Parameters in Patients with Scabies by Mariam Y. Al-Fadhly, Wasan A. Al-Marsomy, Hiba H. Maqdasi .

“…The tests showed that there were no statistically significant differences between the scabies patients and the control group for Hb (12.86± 0.31, 12.88± 0.20), PCV (34.40±0.94, 40.35±0.59), and platelets (244.80±9.58, 237.23±8.97), Respectively. …”
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