Investigation and Identification of let-7a Related Functional Proteins in Gastric Carcinoma by Proteomics by Yimin Zhu, Xingyuan Xiao, Lairong Dong, Zhiming Liu

“…The underexpressed proteins consisted of S-phase kinase-associated protein 2 (Spk2), Platelet membrane glycoprotein, Fibronectin and Cks1 protein. …”
Get full text

Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake Bothrops jararaca by Stella R. Zamuner, Catarina F. P. Teixeira

“…Therefore, the role of the adhesion molecules intercellular adhesion molecule-1 (ICAM-1), LECAM-1, CD18, leukocyte function-associated antigen-1 (LFA-1) and platelet endothelial cell adhesion molecule-1 (PECAM-1) on the BjV-induced neutrophil accumulation and the correlation with release of LTB4, TXA2, tumor necrosis factor-α, interleukin (IL)-1 and IL-6 have been investigated. …”
Get full text

Interleukin-17A Exacerbates Ferric Chloride-Induced Arterial Thrombosis in Rat Carotid Artery by Francesco Maione, Antonio Parisi, Elisabetta Caiazzo, Silvana Morello, Fulvio D'Acquisto, Nicola Mascolo, Carla Cicala

“…Consistent with this, we have recently shown that IL-17A increases human and murine platelet response to ADP. In this study we expanded our previous observation and we describe for the first time an in vivo prothrombotic effect of the cytokine. …”
Get full text

Entropy optimization of stagnant blood flow systems with tetra-hybrid nano additives under viscous dissipation, joule heating and thermal radiation effects by Meena Rajeswari P, Poulomi De

“…Tetra-hybrid nanofluid volume fraction and platelet shape factor for nanoparticles have efficient heat transfer rate. …”
Get full text

Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy by Jingjing Liu, Chunyu Jiang, Xu Ma, Lishuai Feng, Jianbo Wang

“…Notoginsenoside Fc (Fc), a novel saponin isolated from Panax notoginseng, effectively counteracts platelet aggregation. Nevertheless, the potential effects and molecular mechanisms of Fc on reendothelialization have yet to be explored. …”
Get full text

Androgenic Anabolic Steroids Cause Thiol Imbalance in the Vascular Endothelial Cells by Halszka Ponamarczuk, Maria Światkowska, Marcin Popielarski

“…Conclusions: These changes may be related to a thiol-disulfide imbalance and vascular endothelium dysfunction, that are often correlated with abnormal platelet aggregation, inflammation, increased vascular permeability, and vascular smooth muscle cell proliferation—all of which are observed in athletes who abuse AASs.…”
Get full text

Myelodysplasia and Mast Cell Leukemia with t(9;22) by Kathryn J. Lago, Matthew P. Shupe, William N. Hannah, Gopalrao V. N. Velagaleti, Christina Mendiola, Veronica Ortega, Brian R. Haney

“…Over time, she required hospitalizations for platelet transfusions with increased frequency. She developed fatigue and weakness along with gastrointestinal symptoms. …”
Get full text

A Rare Co-Occurrence of Triple Mutations in JAK2, CALR, and MPL in the Same Patient with Myelofibrosis by Sherine J. Thomas, D. P. Dash

“…The patient was started on treatment with hydroxyurea and aspirin with improvement in platelet count and resolution of anemia. Discussion. …”
Get full text

Validation and Refinement of the Baveno VI Criteria for Ruling Out High-Risk Varices by Hong Zhou, Han Hu, Maoyong Tian, Jun Chu, Caiyun Tian, Yanqing Yang, Shide Lin

“…The Baveno VI criteria recommend the use of a simple algorithm based on a liver stiffness measurement<20 kPa through transient elastography and a platelet count>150×109/L for ruling out high-risk varices in patients with compensated advanced chronic liver disease. …”
Get full text

Gestational Age at Delivery Is an Independent Predictor of Neonatal Outcome for Maternal HELLP Syndrome by Yan Shi, Xiaoli Yang, Chengqin Wang, Luosong Zhuoga, Dongmei Xu

“…Abstract Hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome is a severe complication of preeclampsia (PE), with a higher incidence rate in people living at high altitudes, such as Tibet area. …”
Get full text

Predictive Value of Novel Inflammation-Based Biomarkers for Pulmonary Hypertension in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng, Lixin Wang, Rong Zhu

“…Recently, there has been an increasing interest in the potential clinical use of several inflammatory indexes, namely, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic-immune-inflammation index (SII). …”
Get full text

Multidrug Resistance Protein-4 Influences Aspirin Toxicity in Human Cell Line by Isabella Massimi, Ambra Ciuffetta, Flavia Temperilli, Francesca Ferrandino, Alessandra Zicari, Fabio M. Pulcinelli, Maria Pia Felli

“…We found that multidrug resistance protein-4 (MRP4) overexpression has a role in reducing aspirin action in patients after bypass surgery and, very recently, we found that aspirin enhances platelet MRP4 levels through peroxisome proliferator activated receptor-α (PPARα). …”
Get full text

Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis by Xuefeng Liu, Zhiqiang Chen, Meng Yu, Wei Zhou, Xuting Zhi, Tao Li

“…Simultaneous approaches significantly promoted 1-, 3-, and 5-year disease-free survival (DFS) rates and overall survival (OS) rates, prolonged operation time, aggravated intraoperative blood loss, increased white blood cell (WBC) and platelet (PLT) counts at POD 7, and lowered total bilirubin (T-Bil) contents at POD 1 and 7. …”
Get full text

Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans by Ju-Sheng Zheng, Jing Yang, Tao Huang, Xiao-Jie Hu, Ming Luo, Duo Li

“…ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05). …”
Get full text

Protocol for assessing and visualizing cell microaggregate formation in whole blood by imaging flow cytometry by Johannes Krell, Komal Kumar Javarappa, Angie Wenedy, Andrew L. Frelinger, III, Laurent Renia, Clarissa Prazeres da Costa, Martin Schlegel, Percy Knolle, Gerhard Schneider, Oliver Hayden

“…Sample preparation artifacts, activation, and morphological changes of cells are mitigated by omitting erythrocyte lysis and leukocyte isolation while maintaining high-throughput accurate imaging of leukocytes and platelets. : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
Get full text

Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia by Youssef Al-Tonbary, Mohammad Al-Haggar, Rasha EL-Ashry, Sahar EL-Dakroory, Hanan Azzam, Ashraf Fouda

“…Results revealed reduced chemotherapy and radiotherapy toxicity as evidenced by decreasing level of MDA, increasing level of Glu.Px and decreased occurrence of toxic hepatitis, haematological complications, and need for blood and platelet transfusions in group I compared to group II. …”
Get full text

Association between the systemic immune-inflammation index and sarcopenia in older adults: a cross-sectional study by Esra Cataltepe, Eda Ceker, Ayse Fadiloglu, Fatih Gungor, Nermin Karakurt, Zekeriya Ulger, Hacer Dogan Varan

“…To determine the SII, we used the formula: Platelet count (109/mm3)×Neutrophil count (109/mm3) / Lymphocyte count (109/mm3). …”
Get full text

Pre-probiotic effects of different bacterial species in aquaculture: behavioral, hematological and oxidative stress responses by Alak Gonca, Kotan Recep, Uçar Arzu, Parlak Veysel, Atamanalp Muhammed

“…Physiological changes in blood tissue [hematological indices: erythrocyte count (RBC), leukocyte count (WBC), hemoglobin (Hb), hematocrit (Hct), platelet count (PLT), mean cell hemoglobin concentration (MCHC), mean cell hemoglobin (MCH), and mean cell volume (MCV)], oxidative stress responses in liver and gill tissues [malondialdehyde (MDA) level, antioxidant enzyme activities: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GR), glutathione-S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PD)] and acetylcholinesterase (AChE) activity in brain tissue (as neurotoxic biomarker) were investigated. …”
Get full text

An Approach to the Investigation of Thrombocytosis: Differentiating between Essential Thrombocythemia and Secondary Thrombocytosis by Ala Almanaseer, Benjamin Chin-Yee, Jenny Ho, Alejandro Lazo-Langner, Laila Schenkel, Pratibha Bhai, Bekim Sadikovic, Ian H. Chin-Yee, Cyrus C. Hsia

“…A diagnosis of ET was associated with higher hemoglobin, mean corpuscular volume (MCV), red cell distribution width (RDW), and mean platelet volume (MPV), while secondary thrombocytosis was associated with higher body mass index, white blood cells, and neutrophils (p<0.01). …”
Get full text

The Feasibility of Percutaneous Dilatational Tracheostomy in Immunosuppressed ICU Patients with or without Thrombocytopenia by Marianne Angelberger, Michaela Barnikel, Alessia Fraccaroli, Johanna Tischer, Sofía Antón, Alexandra Pawlikowski, Mark op den Winkel, Hans Joachim Stemmler, Stephanie-Susanne Stecher

“…There were no significant differences in leucocyte or platelet count on the tracheostomy day. Patients with coagulation disorders and patients under immunosuppression were distributed equally among both groups. …”
Get full text