Visceral Adipose Tissue Inflammation and Vascular Complications in a Rat Model with Severe Dyslipidemia: Sex Differences and PAI-1 Tissue Involvement by Irena Markova, Martina Hüttl, Natalie Gayova, Denisa Miklankova, Kristyna Cerna, Martina Kavanova, Petra Skaroupkova, Sona Cacanyiova, Hana Malinska

“…Additionally, HHTg females had higher platelet counts, larger platelet volumes, and lower antithrombin inhibitory activity. …”
Get full text

Prognostic factors and survival outcomes in patients with salivary duct carcinoma: a retrospective cohort study by Fei Chen, Liangbo Li, Jingqiao Tao, Nenghao Jin, Liwei Wang, Liang Zhu, Bo Qiao, Lejun Xing, Bo Wei, Jingqiu Bu, Haizhong Zhang

“…Multivariate analysis identified platelet count (HR 0.99, 95%CI 0.98–1.00, P = 0.011) and distant metastasis (HR 2.79, 95%CI 1.38–5.64, P = 0.004) as independent prognostic factors for OS. …”
Get full text

Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…Theoretical simulations and experimental studies were combined to optimize their structure and functionality. In vitro platelet aggregation, antibacterial assays, cytotoxicity tests, and hemolysis evaluations were performed. …”
Get full text

Analysis of clinical characteristics of hemorrhagic fever with renal syndrome with acute pancreatitis: a retrospective study by Lihua Huang, Min Xiao, Xiaoling Huang, Jun Wu, Jiao Luo, Fuxing Li, Wei Gu

“…Smoking, elevated ferritin and white blood cell levels, decreased fibrinogen and platelet levels are more susceptible to developing AP.…”
Get full text

CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine by Antoine Dewitte, Julien Villeneuve, Sébastien Lepreux, Marion Bouchecareilh, Xavier Gauthereau, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche

“…Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the involvement of blood platelets in driving inflammation is increasingly stressed. …”
Get full text

Evaluation of Sialic Acid Levels in the Umbilical Cord Blood of Newborns of Diabetic and Non-Diabetic Mothers and the Relation with Poor Neonatal Outcome by Yuksel Kurban, İbrahim Uyar, Koza Murat, Murat Alan

“…Sialic acid levels of the participants were assessed from the newborn cord blood within the first 6-24 hours postnatally. Also mean platelet volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, platelet, bilirubin values were recorded as well as the age, gravida, parity, gestational week of the participant mothers and type of delivery, gender, weight, height and the APGAR score of the newborn, and whether insulin was used or not. …”
Get full text

Guanxinning Tablet Attenuates Coronary Atherosclerosis via Regulating the Gut Microbiota and Their Metabolites in Tibetan Minipigs Induced by a High-Fat Diet by Qinqin Yang, Yanyun Xu, Liye Shen, Yongming Pan, Junjie Huang, Quanxin Ma, Chen Yu, Jiaojiao Chen, Yu Chen, Minli Chen

“…We simultaneously detected blood lipid levels, observed ventricular function using ultrasound examination, measured platelet aggregation, and checked changes in inflammatory factors, oxidative stress factors, and vascular endothelial injury-related indexes applying ELISA assays. …”
Get full text

Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease by Toni Ibrahim, Fady El Karak, Assem Araji, Elie El Rassy

“…Therefore, strict monitoring of the platelet count is required in patients who develop allergic reactions to tirofiban.…”
Get full text

BNT162b2 COVID-19 Vaccine Induced Immune Thrombocytopenic Purpura by A. K. Ghosh, S. Bhushan, L. D. R. Lopez, D. Sampat, Z. Salah, C. A. Hatoum

“…Herein, we present a patient who presented with severe ITP with a platelet count of 0 after receiving the second dose of the BNT162b2 mRNA COVID-19 vaccine (also known as the Pfizer BioNTech). …”
Get full text

Lycopene improves on basic hematological and immunological parameters in diabetes mellitus by Ejike, Daniel Eze, Adam, Moyosore Afodun, Josephine, Kasolo, Keneth Iceland, Kasozi

“…There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet counts and stable albumin, globulin levels. …”
Get full text

Lycopene improves on basic hematological and immunological parameters in diabetes mellitus by Ejike, Daniel Eze, Adam Moyosore, Afodun, Josephine, Kasolo, Keneth Iceland, Kasozi

“…There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet counts and stable albumin, globulin levels. …”
Get full text

Predictive Laboratory Markers for Gastrointestinal Complications in Children with Henoch-Schönlein Purpura by Guo Q, Xia S, Ding Y, Liu F

“…Detailed demographic and laboratory data, including WBC count, lymphocyte count, neutrophil count, platelet count, hemoglobin, NLR, PLR, MPV, MPR, C-reactive protein, ESR, albumin, BUN, creatinine, sodium, potassium, calcium, IgA, PT, aPTT, and INR, were collected. …”
Get full text

Impact of type 2 diabetes mellitus on low-grade inflammation in patients with ST-elevated myocardial infarction by M.V. Bielinskyi, N.M. Seredyuk, A.I. Vytryhovskiy, V.D. Koroliuk

“…In summary, the findings from the study provide compelling evidence to support the notion that patients who suffer from both STEM and T2DM exhibit a more robust inflammatory response and higher platelet count, compared to those with STEMI alone. …”
Get full text

Identification of quality markers and mechanisms of Anzi Tiaochong Fang in the treatment of antiphospholipid syndrome-related recurrent pregnancy loss: chemical analysis, network p... by Shan He, Fei Ma, Jia Li, Da-yan Liu, Zhi-wei Wang, Peng-dian Chen, Jia-man Wu, Hong Chang, Yan Ning

“…GO analysis demonstrated significant enrichment in cytokine-mediated signaling pathway, positive regulation of angiogenesis, response to hypoxia, inflammatory response, and platelet degranulation. Reactome analysis indicated significant enrichment in Immune System, Cytokine Signaling in the Immune system, Signaling by Interleukins, Platelet activation, signaling and aggregation, and Signaling by VEGF. …”
Get full text

Systemic Immune-inflammation Index in Evaluation of Inflammation in Rheumatoid Arthritis Patients by Amela DERVISEVIC, Almir FAJKIC, Elmedina JAHIC, Lejla DERVISEVIC, Zurifa AJANOVIC, Enisa ADEMOVIC, Asija ZACIRAGIC

“…Blood samples were tested for the next parameters: leukocytes, neutrophilic granulocytes, lymphocytes, thrombocytes [platelet (PLT)], high-sensitivity hs-CRP, sed rate [erythrocyte sedimentation rate (ESR)], neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR). …”
Get full text

Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

“…Several other abnormalities in endothelial and platelet activation were identified (including elevated soluble P-selectin, elevated von Willebrand factor, and elevated vascular endothelial growth factor) but these did not change with treatment or predict outcome. …”
Get full text

Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting by Murat Selçuk, Tufan Çınar, Faysal Şaylık, Selami Doğan, Ismail Selçuk, Ahmet L. Orhan

“…The SII is determined using the following equation: neutrophil (N) × platelet (P) ÷ lymphocyte (L). Results: The incidence of PoAF in the present study was 24% (n=97 cases). …”
Get full text

The Relationship Between Novel Inflammatory Markers and Serum 25‐Hydroxyvitamin D Among US Adults by Hang Zhao, Yangyang Zhao, Yini Fang, Weibang Zhou, Wenjing Zhang, Jiecheng Peng

“…However, few studies have incorporated novel inflammatory markers such as the platelet‐to‐lymphocyte ratio (PLR), platelet‐to‐high density lipoprotein cholesterol ratio (PHR), systemic inflammatory index (SII), neutrophil‐to‐lymphocyte ratio (NLR), systemic inflammatory response (SIRI), and neutrophil‐to‐high‐density lipoprotein cholesterol ratio (NHR). …”
Get full text

Noninvasive Assessment of Liver Fibrosis by Magnetic Resonance Elastography in Patients with Rheumatic Disease on Long-Term Methotrexate Treatment by Arindam Nandy Roy, Anjani Kumar Darapureddy, Yarram Ashok Kumar

“…Around 37.5% (n = 18) of the patients had abnormal aspartate transaminase (AST)-to-platelet count ratio index (APRI) score. The mean MRE value of the study group was 2.83 ± 0.90 kPa. …”
Get full text

Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children’s Winter Respiratory Infections in Xinjiang by Wang L, Wang W, Wang J, Zhu L, Luo J

“…We compared differences in hsCRP, platelet count, White Blood Cells(WBC), and Neutrophil(NE) among the groups.Results: We conducted a systematic sorting and analysis of variables exhibiting significant differences. …”
Get full text