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161
Prevalence of β-lactam antibiotic resistance of Escherichia coli isolated from a neonatal intensive care unit
Published 2025-02-01“…Conjugation experiments were conducted to analyze the horizontal transferability of resistance genes on plasmids. Genomic DNA was extracted for whole genome sequencing, construction of plasmid physical maps, locating resistance genes, and analyzing flanking regions and the resistance gene-related sequences. …”
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162
Synthesis, Characterization, DNA Binding, and Photocleavage Activity of Oxorhenium (V) Complexes with α-Diimine and Quinoxaline Ligands
Published 2010-01-01“…Upon irradiation, complex 1 was found to promote the cleavage of plasmid pBR 322 DNA from supercoiled form I to nicked form II. …”
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163
Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan
Published 2025-01-01“…Hybrid genomic assembly indicated that mcr-1 is carried on IncI2 plasmids. Plasmid replicon typing indicated that IncI2-type plasmids (n = 10) were the most prevalent plasmids in these strains, followed by IncFIB (n = 8), IncFIC (n = 7), IncFIA (n = 6), IncFII (4), IncQ1 (n = 3), IncI1 (n = 1), IncY (n = 1), and IncN (n = 1). …”
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164
Accurate phenotype-to-genotype mapping of high-diversity yeast libraries by heat-shock-electroporation (HEEL)
Published 2025-02-01“…HEEL also allows more than 107 yeast cells per reaction to be transformed with a circular plasmid molecule, which corresponds to an almost 100-fold improvement compared with current yeast transformation methods. …”
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165
The Evolution of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> and New Strategies to Fight It
Published 2025-01-01“…Also, the evolution of drug resistance in <i>A. baumannii</i>, which is mainly driven by mobile genetic elements, is reported, with particular reference to plasmid-associated resistance, resistance islands, and insertion sequences. …”
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166
DNA Interaction and DNA Cleavage Studies of a New Platinum(II) Complex Containing Aliphatic and Aromatic Dinitrogen Ligands
Published 2011-01-01“…It is remarkable that this complex has the ability to cleave the supercoiled plasmid.…”
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167
Study on the Color Genesis of South Red Agate and the Geological Characteristics of the Siliceous Gravel Layer
Published 2022-01-01“…The matrix structure of the sample is mainly long fiber and short fiber, and some of them are fine-grained and crystalline plasmid. There are concentric ring-banded structures, and some horizontal banded and vein structures can also be seen. …”
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168
Drug Resistance Mechanism of Enterobacteriaceae with Decreased Antibiotic Sensitivity
Published 2022-01-01“…The results showed that the enzyme-linked immunosorbent assay titer of acrB antibody was 1:40,000, and the preparation of acrB antibody was successful. Plasmid-mediated deletion of IMP-1 metallo-β-lactamase binding outer membrane protein is one of the main reasons for the decrease of antibiotic sensitivity.…”
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169
When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria
Published 2012-01-01“…Implications on bacterial evolution through stabilization/transfer of genetic material (phage or plasmid DNA) as a result of ribonucleases' functions will be covered. …”
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170
Non-Beta-Lactamase-Producing Penicillin-Resistant Enterococcus faecium in a Clinical Setting
Published 1990-01-01“…These strains did not produce beta-lactamase and no plasmid DNA could be detected. It is postulated that the mechanism of resistance is one or more chromosomally mediated alterations of penicillin-binding proteins.…”
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171
Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii group in Taiwan
Published 2025-01-01“…Whole-genome sequencing of a blaNDM-1-carrying A. seifertii strain revealed a plasmid transferable via in vitro conjugation, suggesting A. seifertii may be a reservoir for NDM-1 plasmids.IMPORTANCECarbapenem-resistant Acinetobacter spp. have been identified by the World Health Organization as a top priority for new antibiotic development. …”
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172
Mechanism of Gene Amplification via Yeast Autonomously Replicating Sequences
Published 2015-01-01“…The gene amplification assays showed that plasmid bearing APS from yeast and human beings led to enhanced protein concentration as compared to the wild type. …”
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173
Computational Studies of 4-Formylpyridinethiosemicarbazone and Structural and Biological Studies of Its Ni(II) and Cu(II) Complexes
Published 2019-01-01“…These complexes also promote hydrolytic cleavage of plasmid pBR322. The ligand (H4FPT) and its complexes showed moderate-to-good activity against Gram-positive and Gram-negative bacterial strains. …”
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174
<i>Helicobacter pylori</i> HP0135 Is a Small Lipoprotein That Has a Role in Outer Membrane Stability
Published 2025-01-01“…Deletion of <i>hp0135</i> in <i>H. pylori</i> B128 resulted in morphological abnormalities that included extensive formation of outer membrane vesicles and increased frequency of mini-cells. Introducing a plasmid-borne copy of <i>hp0135</i> into the <i>H. pylori</i> Δ<i>hp0135</i> mutant suppressed the morphological abnormalities. …”
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175
Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands
Published 2025-02-01“…We also identified a diverse plasmidome with 23 different plasmid replicon types. The E. coli isolates were phenotypically antimicrobial resistant, predominantly multidrug resistant. …”
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176
The Laboratory Diagnosis of Neisseria gonorrhoeae
Published 2005-01-01“…The useful typing methods for determining strain relatedness include auxotyping, serotyping, plasmid profile analysis, DNA sequencing of the porB gene and pulsed-field gel electrophoresis. …”
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177
EFFECT OF p30 RECOMBINANT PROTEIN ON AFRICAN SWINE FEVER VIRUS IN VITRO REPRODUCTION
Published 2018-10-01“…The results of the study of purified recombinant protein p30 effect, derived from E. coli clone, containing pET32b(+)/р30 plasmid, on ASFV in vitro reproduction are presented. …”
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178
Development of Transgenic Papaya through Agrobacterium-Mediated Transformation
Published 2013-01-01“…Transgenic papaya plants were regenerated from hypocotyls and immature zygotic embryo after cocultivation with Agrobacterium tumefaciens LBA-4404 carrying a binary plasmid vector system containing neomycin phosphotransferase (nptII) gene as the selectable marker and β-glucuronidase (GUS) as the reporter gene. …”
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179
The frequency of mutations in the penA, mtrR, gyrA and parC genes of Neisseria gonorrhoeae, the presence of tetM gene and antibiotic resistance/susceptibility: a systematic review...
Published 2025-01-01“…Less than 50% of the isolates with intermediate resistance to ciprofloxacin had mutations in parC. The plasmid containing the tetM gene was found in more than 50% of tetracycline-resistant isolates. …”
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180
The Spread of Antibiotic Resistance Genes In Vivo Model
Published 2022-01-01“…Most drug resistance genes are located on plasmids, and the spread of drug resistance genes among microorganisms through plasmid-mediated conjugation transfer is the most common and effective way for the spread of multidrug resistance. …”
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