Showing 1 - 20 results of 156 for search '"plasma membrane"', query time: 0.06s Refine Results
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    Cryo-electron tomography pipeline for plasma membranes by Willy W. Sun, Dennis J. Michalak, Kem A. Sochacki, Prasanthi Kunamaneni, Marco A. Alfonzo-Méndez, Andreas M. Arnold, Marie-Paule Strub, Jenny E. Hinshaw, Justin W. Taraska

    Published 2025-01-01
    “…Existing sample preparation methods are insufficient at accessing the plasma membrane and its associated proteins. Here, we present a correlative cryo-electron tomography pipeline optimally suited to image large ultra-thin areas of isolated basal and apical plasma membranes. …”
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    Plasma Membrane Transporters in Modern Liver Pharmacology by Jose J. G. Marin

    Published 2012-01-01
    “…Since most drugs cannot cross the plasma membrane by simple diffusion, the involvement of transporters is mandatory. …”
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    Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer by Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho

    Published 2025-02-01
    “…Abstract The development of metastasis is a leading cause of cancer-related death that involves specific changes in the plasma membrane (PM) and nucleus of cancer cells. Elevated levels of membrane lipids, including sphingomyelin, cholesterol, and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), in the PM, contribute to changes in membrane rigidity, lipid raft formation, and actin polymerisation dynamics, processes that drive cell invasion. …”
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    The steady-state level of plasma membrane ceramide is regulated by neutral sphingomyelinase 2 by Anne G. Ostermeyer-Fay, Abhay Kanodia, Ranjana Pathak, Maria Jose Hernandez-Corbacho, Aarnoud C. van der Spoel, Yusuf A. Hannun, Daniel Canals

    Published 2025-01-01
    “…One of these pools of ceramide resides in the plasma membrane, and several works have suggested that an increase in plasma membrane ceramide (PMCer) in response to stimulation leads to cell death and modulates cell adhesion and migration. …”
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    Altered shear stress of blood flow causes plasma membrane damage in endothelial cells by Nikita Raj, Chang Pan, Ann Marleen Starke, Anna L. L. Matos, Oliver Soehnlein, Volker Gerke

    Published 2025-02-01
    “…However, whether SS of blood flow can indeed affect plasma membrane integrity of endothelial cells and whether any ruptures occurring are repaired is not understood. …”
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    Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo by Ellen D. Stück, Randolph N. Christensen, J. Russell Huie, C. Amy Tovar, Brandon A. Miller, Yvette S. Nout, Jacqueline C. Bresnahan, Michael S. Beattie, Adam R. Ferguson

    Published 2012-01-01
    “…TNFα contributes to excitotoxicity by increasing GluA2-lacking AMPA receptor (AMPAR) trafficking to the neuronal plasma membrane. In vitro, increased AMPAR on the neuronal surface after TNFα exposure is associated with a rapid internalization of GABAA receptors (GABAARs), suggesting complex timing and dose dependency of the CNS’s response to TNFα. …”
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    Silica Induces Changes in Cytosolic Free Calcium, Cytosolic pH, and Plasma Membrane Potential in Bovine Alveolar Macrophages by Attila Tárnok, Thomas Schlüter, Ingeborg Berg, Günther Gercken

    Published 1997-01-01
    “…Short‐term incubation (10 min) of BAM with silica gel and quartz dust particles induced increases in the cytosolic free calcium concentration ([Ca2+]i), decreases in intracellular pH (pHi), and increases in plasma membrane potential (PMP). The extent of these changes was concentration dependent, related to the type of dust and was due to Ca2+ influx from the extracellular medium. …”
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    4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions by Sujin Park, Yoon A Kim, Jaewang Lee, Hyunsoo Seo, Sang-Jip Nam, Dong-Gyu Jo, Dong-Hoon Hyun

    Published 2023-07-01
    “…Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases, including mitochondrial dysfunction. Plasma membrane (PM) redox enzymes are crucial in maintaining cellular physiology and redox homeostasis in response to mitochondrial dysfunction. …”
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    The Plasma Membrane Ca2+-ATPase2 (PMCA2) Is Involved in the Regulation of Purkinje Cell Dendritic Growth in Cerebellar Organotypic Slice Cultures by Pradeep Sherkhane, Josef P. Kapfhammer

    Published 2013-01-01
    “…We have now studied the role of the plasma membrane Ca2+-ATPase2 (PMCA2), a major calcium extrusion pump, for Purkinje cell dendritic development. …”
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    tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells by Aishwarya A. Makam, Shruti Sharma, Prajwal Nagle, Nandhini M. Sundaram, Vidya Mangala Prasad, Nikhil R. Gandasi

    Published 2025-02-01
    “…Abstract Pancreatic β‐cells secrete insulin stored in large dense core vesicles (LDCV) by fusion of vesicle and plasma membrane during a process called insulin exocytosis. …”
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    Cell Secretion: Current Structural and Biochemical Insights by Saurabh Trikha, Elizabeth C. Lee, Aleksandar M. Jeremic

    Published 2010-01-01
    “…In regulated (calcium-dependent) secretion, membrane-bound secretory vesicles dock and transiently fuse with specialized, permanent, plasma membrane structures, called porosomes or fusion pores. …”
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