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121
Ethnicity-specific distribution of <em>TRPM8</em> gene variants in Eurasian populations: signs of selection
Published 2020-05-01“…These exons encode parts of the N-terminus, which is necessary for channel functioning in the plasma membrane of neurons. The rs11563071 is in exon 23 encoding part of the C-terminus. …”
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122
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling
Published 2025-01-01“…Reduced ERK phosphorylation was dependant on EGFR and NRF2 activation. Furthermore, plasma membrane lipids were investigated via confocal microscopy, revealing reduced cholesterol and lipid rafts. …”
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123
Development of a Ten-lncRNA Signature Prognostic Model for Breast Cancer Survival: A Study with the TCGA Database
Published 2020-01-01“…The Gene Ontology (GO) function and KEEG pathway analysis was primarily enriched in immune response, receptor binding, external surface of plasma membrane, signal transduction, cytokine-cytokine receptor interaction, and cell adhesion molecules (CAMs). …”
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124
Chemical, Spectral, Biological, and Toxicological Studies of Some Benzene Derivatives Used in Pharmaceuticals: In Silico Approach
Published 2024-12-01“…Benzene metabolites are distinct from chemical metabolites apart from benzene, which is lipophilic in nature and binds to cellular membranes, in that they bind to the intracellular plasma membrane where they produce degenerative alterations. …”
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125
Ginsenoside Rk2 alleviates hepatic ischemia/reperfusion injury by enhancing AKT membrane translocation and activation
Published 2025-01-01“…Rk2 directly binds to AKT1, facilitating its translocation from the cytoplasm to plasma membrane. This process markedly enhanced AKT interaction with PDPK1, promoting the activation of AKT1 and its downstream signaling. …”
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126
Comparison of the Effect of Adding Different Levels of Zinc Chloride, Curcumin, Zinc Oxide Nanoparticles (Zano‐NPs), Curcumin Loaded on Zano‐NPs on Post‐Thawing Quality of Ram Seme...
Published 2024-11-01“…Sperm motility, viability, DNA and plasma membrane integrity, total abnormalities and malondialdehyde (MDA) generation were all evaluated in treatment groups after thawing. …”
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127
Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure
Published 2020-01-01“…In contrast, expressions of CD29—a subunit of the fibronectin receptor—or of the tetraspanin CD9 were lower after extended treatment with the DPP-4 inhibitors; less of the CD9 was seen at the plasma membrane after prolonged exposure to sitagliptin. …”
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128
Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines
Published 2024-01-01“…Galectin-1 was predominantly localized at the plasma membrane. Notable differences in galectin-3 localization and distribution were observed between HTR-8/SVneo cells and choriocarcinoma cells. …”
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129
Exosomes and Their Therapeutic Potentials of Stem Cells
Published 2016-01-01“…Exosomes, a group of vesicles originating from the multivesicular bodies (MVBs), are released into the extracellular space when MVBs fuse with the plasma membrane. Numerous studies indicate that exosomes play important roles in cell-to-cell communication, and exosomes from specific cell types and conditions display multiple functions such as exerting positive effects on regeneration in many tissues. …”
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130
Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men
Published 2021-01-01“…In recent years, a growing body of evidence has shown that circulating SHBG not only is a passive carrier for steroid hormones but also actively regulates testosterone signaling through putative plasma membrane receptors and by local expression of androgen-binding proteins apparently to reach local elevated testosterone concentrations in specific androgen target tissues. …”
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131
Foliar application of nano biochar solution elevates tomato productivity by counteracting the effect of salt stress insights into morphological physiological and biochemical indice...
Published 2025-01-01“…NBS application stabilized the plasma membrane via reducing electrolyte leakage by 30% as well as reduced the lipid peroxidation rates by 46% and 29% under non-stressed and stressed plants, respectively. 3% NBS application also significantly enhanced the plants primary and secondary metabolites, as well as activities of antioxidant enzymes compared to control plants. …”
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132
The grapevine ABC transporter B family member 15 is a trans-resveratrol transporter out of grapevine cells
Published 2025-01-01“…VvABCB15-YFP fusion proteins in Nicotiana leaf showed localization in the plasma membrane, consistent with a functional role in trans-resveratrol transport. …”
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133
Eksplorasi Permeabilitas Membran : Teori dan Percobaan
Published 2023-11-01“…Hasil penelitian menunjukka bahwa pengaruh garam yang dilarutkan dalam air sebanyak 50 ml pada kentang menunjukkan dampak yang signifikan terhadap berat dan tekstur jaringan kentang. saat teh dimasukkan ke dalam air panas, molekul air di sekitarnya memiliki energi kinetik yang tinggi, memungkinkan molekul-molekul teh yang larut untuk lebih mudah bergerak dari daerah dengan konsentrasi tinggi (teh yang belum larut) ke daerah dengan konsentrasi rendah (air). methanol lebih efektif dalam mempercepat reaksi dibandingkan dengan etanol, baik pada konsentrasi mutlak maupun setelah pengenceran menggunakan konsentrasi larutan Kata Kunci : Permeabilitas Membran, Difusi, Osmosis, Kelarutan Lipid. Â Â Â The plasma membrane is a thin layer that completely surrounds the cell, consisting of a phospholipid bilayer with embedded proteins, serves a vital function in maintaining cell integrity as well as regulating the movement of substances, and has a dynamic structure that allows its components to move laterally within the fluidity of the membrane. …”
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134
Phosphorylation of Arabidopsis NRT1.1 regulates plant stomatal aperture and drought resistance in low nitrate condition
Published 2025-01-01“…This finding identified a novel drought resistance mechanism enabled by post-transcriptional regulation of plasma membrane transporter.…”
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135
SuessR: Regional corrections for the effects of anthropogenic CO2 on δ13C data from marine organisms
Published 2021-08-01“…The magnitude of the Suess effect calculated by SuessR aligns with published estimates, whereas the Laws effect is smaller than previously calculated, resulting from updated estimates of average community cell sizes, growth rates and permeability of phytoplankton plasmalemmas (the plasma membrane which bounds the cell) to CO2. The increasing magnitude of the Suess effect means this phenomenon is no longer only of concern to historical ecologists, but now affects contemporary ecological studies using δ13C data. …”
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136
Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes
Published 2025-01-01“…Western blotting and immunohistochemistry analysis showed the density of the sodium-potassium-chloride co-transporter (NKCC2) was significantly reduced in kidney cortex membrane fractions of juvenile mice that received hAAT compared to vehicle.ConclusionTaken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”
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137
The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity
Published 2025-02-01“…Actin-based motility of R. parkeri enables bacteria to enter protrusions of the host cell plasma membrane that are engulfed by neighboring host cells. …”
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138
Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae)
Published 2012-01-01“…Using the purified warifteine, the 50% inhibitory concentration (IC50) was determined at 0.08 mg/mL after 72 h in culture, inducing significant changes in the parasite morphology, like aberrant multisepted forms and blebs in the plasma membrane. In conclusion, warifteine represents an attractive candidate for future pharmacological studies aiming new leishmanicidal drugs.…”
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139
Molecular characterization of siderophore biosynthesis in Paracoccidioides brasiliensis
Published 2020-06-01“…Paracoccidioides spp. present orthologous genes encoding the enzymes necessary for the biosynthesis of hydroxamates, and plasma membrane proteins related to the transport of these molecules. …”
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140
Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm
Published 2023-11-01“…Post-thaw evaluation revealed that 0.5 and 1mM crocin improved total motility, plasma membrane integrity, acrosome integrity, mitochondrial membrane potential, and viability, and one and 1.5mM crocin enhanced catalase activity and reduced lipid peroxidation compared to control (p<0.05). …”
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