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61
Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
Published 2025-01-01“…Here, we review the origins of ETI and focus on 5 mechanisms, in which the key steps of a pathway can include activation of a caspase by a RIPoptosome or inflammasome, formation of pores in the plasma membrane, release of cytokines and ending in cell death by pyroptosis. …”
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62
An Ultrastructural and Fluorescent Study of the Teratocytes of Microctonus aethiopoides Loan (Hymenoptera: Braconidae) from the Hemocoel of Host Alfalfa Weevil, Hypera postica (Gyl...
Published 2014-01-01“…Teratocytes were stained with various specific fluorescent dyes for plasma membrane, Golgi, nuclei, lysosomes, mitochondria, and endoplasmic reticulum (ER). …”
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63
Dexamethasone reduces cell surface levels of CD11b on human eosinophils
Published 1997-01-01“…Overnight incubation of human eosinophils (Eøs) with the glucocorticoid hormone dexamethasone (DEX; 0.1 μM) resulted in lower expression of the CD11b, but not CD49d, antigen on their plasma membrane, as assessed by flow cytometry. DEX produced a consistent inhibitory effect (ranging from 16% to 20%) when tested at a concentration of 0.1 μM. …”
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64
ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives
Published 2019-01-01“…PR3 is a bactericidal protein expressed by neutrophilic granules and on their plasma membrane. Derangements in its expression and function have been linked to leukemias and GPA alike. …”
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65
Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery
Published 2025-02-01“…Differences in hydrophobicity of plasma membrane and pulmonary surfactant require different chemistries of gene carriers to improve efficacy. …”
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66
Potential Role of Sugar Transporters in Cancer and Their Relationship with Anticancer Therapy
Published 2010-01-01“…Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. Cancer cells are well known to display an enhanced sugar uptake and consumption. …”
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67
Effect of Addition of Taurine on the Liquid Storage (5°C) of Mithun (Bos frontalis) Semen
Published 2013-01-01“…The present study was undertaken to assess the effect of taurine on sperm motility, viability, total sperm abnormalities, acrosomal and plasma membrane integrity, enzymatic profiles such as reduced glutathione (GSH), glutathione peroxidase (GPX), superoxide dismutase (SOD), and catalase (CAT), and biochemical profiles such as cholesterol efflux and malondialdehyde (MDA) production. …”
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68
The Role of FRMD7 in Idiopathic Infantile Nystagmus
Published 2012-01-01“…FRMD7 contains a conserved N-terminal FERM domain suggesting that it may provide a link between the plasma membrane and actin cytoskeleton. Limited studies together with the knowledge of the function of other FERM domain containing proteins, suggest that FRMD7 may play a role in membrane extension during neuronal development through remodeling of the actin cytoskeleton.…”
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69
Neratinib as a Potential Therapeutic for Mutant RAS and Osimertinib-Resistant Tumours
Published 2022-09-01“…This resulted in ezrin dephosphorylation and the plasma membrane becoming flaccid. Neratinib disrupted the nanoclustering of RAC1, which was associated with dephosphorylation of PAK1 and Merlin, and with increased phosphorylation of the Merlin binding partners large tumour suppressor kinase 1/2, YAP, and TAZ. …”
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70
Capacitance Measurements of Exocytosis From AII Amacrine Cells in Retinal Slices
Published 2025-01-01“…However, electrophysiological recordings can directly quantify the presynaptic release of neurotransmitters with high temporal resolution by measuring the membrane capacitance before and after exocytosis, as fusion of the membrane of presynaptic vesicles with the plasma membrane increases the total capacitance. While the standard technique for capacitance measurement assumes that the presynaptic cell is unbranched and can be represented as a simple resistance-capacitance (RC) circuit, neuronal exocytosis typically occurs at a distance from the soma. …”
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71
SERINC5 counters retroviruses and non-retroviruses
Published 2025-01-01“…SERINC5 (serine incorporator 5), a member of the serine incorporator family, has been identified as a retrovirus restriction factor that inhibits the fusion of virions with the plasma membrane, thus blocking the release of the viral core into target cells and subsequently attenuating viral infectivity. …”
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72
The Genetics and Breeding of Heat Stress Tolerance in Wheat: Advances and Prospects
Published 2025-01-01“…Heat stress also leads to the generation of reactive oxygen species that disrupt the membrane systems of thylakoids, chloroplasts, and the plasma membrane. The deactivation of the photosystems, reduction in photosynthesis, and inactivation of Rubisco affect the production of photo-assimilates and their allocation, consequently resulting in reduced grain yield and quality. …”
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73
Effects of the dynamics of noise-induced calcium signals in a biophysical model of the astrocytic process
Published 2025-01-01“…The model describes the process of generation of spontaneous Ca2+ signals induced by the stochastic activation of voltage-dependent Ca2+ channels on the plasma membrane of the astrocyte. The model allows us to study the dynamics of the propagation of spontaneous local Ca2+ signals and the mechanisms of formation of spatial Ca2+ patterns in the astrocytic process. …”
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74
Live imaging of paracrine signaling: Advances in visualization and tracking techniques
Published 2025-01-01“…Paracrine factor secretion can be directly visualized by fluorescent protein tagging to ligand, or indirectly by visualizing the cleavage of the transmembrane pro-ligands or plasma membrane fusion of endosomes comprising the paracrine factors. …”
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75
Comparison of natural and artificial vasopressin deficiency: why the latter is lethal?
Published 2016-05-01“…AVP exerts its effect through specific plasma membrane receptors. V1a receptors can induce vasoconstriction maintaining blood pressure during hypovolemia. …”
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76
Platelet microparticles level in juvenile idiopathic arthritis: A pediatric population-based cross-sectional study in a tertiary care center
Published 2019-01-01“…Background: Platelet-derived microparticles (PMPs) are small vesicles that are released from the plasma membrane upon platelet activation, which are then involved in haemostasis, vascular health, and have recently been shown to be intimately involved in immune responses. …”
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77
Platelet Responses in Cardiovascular Disease: Sex-Related Differences in Nutritional and Pharmacological Interventions
Published 2020-01-01“…., hormonal status and traditional cardiovascular risk factors), together with platelet-related factors (e.g., plasma membrane composition, receptor signaling, and platelet-derived microparticles) can elucidate sex-related disparity in platelet functionality and CVD onset and outcome, especially in relation to efficacy of current primary and secondary interventional strategies. …”
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78
Cytotoxic and Genotoxic Effects of Acephate on Human Sperm
Published 2017-01-01“…Subsequently, sperm motility, vitality, functional integrity of plasma membrane, sperm capacitation, and DNA damage were examined. …”
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79
Small-Molecule Hormones: Molecular Mechanisms of Action
Published 2013-01-01“…In addition, small-molecule hormones modify the function of the cell by a number of nongenomic mechanisms, involving interaction with proteins localized in the plasma membrane, in the cytoplasm, as well as with proteins localized in other cellular membranes and in nonnuclear cellular compartments. …”
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80
Trafficking in cancer: from gene deregulation to altered organelles and emerging biophysical properties
Published 2025-01-01“…Intracellular trafficking supports all cell functions maintaining the exchange of material between membrane-bound organelles and the plasma membrane during endocytosis, cargo sorting, and exocytosis/secretion. …”
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