The Global Burden and Trends of Legionella spp. Infection-Associated Diseases from 1990 to 2021: An Observational Study by Yonghong Zhong, Linfeng Shen, Yan Zhou, Yibo Sun, Xiaofang Fu, Huaqiong Huang

“…Conclusion Higher disease burdens and increasing trends have been observed in specific age groups and regions, which require the implementation of water quality management plans, enhanced readiness of health facilities, and improved sanitation infrastructure.…”
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Production of β-lactoglobulin (BLG) gene knock- out blastocyst stage embryos of Indian water buffalo using CRISPR and SCNT technology by Aseem Tara, Priyanka Singh, Devika Gautam, Gaurav Tripathi, Shreya Malhotra, Sacchinandan De, Manoj K. Singh, Naresh L. Selokar

“…Keeping this in mind, we planned to utilize the CRISPR tools to disrupt the buffalo β-lactoglobulin (BLG) gene to produce hypoallergenic milk in the long run. …”
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Non-pharmacological interventions for the reduction and maintenance of blood pressure in people with prehypertension: a systematic review protocol by Paul Rutter, Andrew Clegg, Valerio Benedetto, Caroline Watkins, Nefyn Williams, Joseph Spencer, Lucy Hives, Emma P Bray, Cath Harris, Rachel F Georgiou, Nafisa Iqbal

“…Heterogeneity will be assessed through visual inspection of forest plots and the calculation of the χ2 and I2 statistics and causes of heterogeneity will be assessed where sufficient data are available. If possible, we plan to investigate differential effects on specific subgroups and from different types of interventions using meta-regression. …”
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Perioperative nursing management of transcatheter edge-to-edge repair (经导管二尖瓣缘对缘修复术围手术期护理) by LIU Yuan (刘苑), LAI Jianqing (赖间清), DING Fei (丁菲), HUANG Huifen (黄惠芬)

“…Based on the fine management model, a goal-directed fluid management plan assisted with the impedance gardiography was established. …”
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Developing a core outcome set for assessing interventions and care for parents after neonatal death in high-income countries (iCHOOSE Neonatal study): protocol for a mixed-methods... by James Webbe, Mehali Patel, Danya Bakhbakhi, Christy Burden, Mary Lynch, Laura Timlin, Lisa Hinton, Abigail Fraser, Anna Davies, Maggie Redshaw, David Odd, Charlotte Williams, Dimitris Siasakos, Abi Merriel, Sadie Mullin, Lucy Moy, Leanne Watts

“…A parent involvement group and stakeholder steering committee have been established and have informed each planned phase: (1) systematic review of quantitative studies evaluating care and interventions provided after neonatal death, to describe interventions, outcomes and outcome measurement tools used to assess intervention effectiveness; (2) qualitative interviews with parents who have experienced neonatal death to identify outcomes important and relevant to them; (3) think-aloud interviews with stakeholders (bereaved parents, healthcare professionals and other stakeholders) to develop and refine an online survey; (4) real-time online international Delphi survey with bereaved parents, healthcare professionals and other stakeholders to shortlist outcomes for consideration in the COS; (5) adapted nominal group online consensus meetings with parents, healthcare professionals and other stakeholders to agree final COS and (6) identification of a preliminary set of measurement tools.Ethics and dissemination Ethical approval has been granted for all activities to be undertaken by the University of Bristol Health Sciences Faculty Research Ethics Committee (reference: 15121). …”
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Analyzing Gait Dynamics and Recovery Trajectory in Lower Extremity Fractures Using Linear Mixed Models and Gait Analysis Variables by Mostafa Rezapour, Rachel B. Seymour, Suman Medda, Stephen H. Sims, Madhav A. Karunakar, Nahir Habet, Metin Nafi Gurcan

“…In conclusion, our findings emphasize the importance of fracture-specific rehabilitation strategies, focusing on infection prevention and individualized treatment plans to optimize recovery outcomes.…”
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A service ecosystems perspective to explore social prescribing value co-creation for vulnerable young people in NEET situation by Isabel Farina, Daniela Sangiorgi, Cristina Masella, Ilaria Simonelli, Regina Alves, Maria J. Marques, Sonia Dias, Carina Dantas, Sabrina Herzog, Sara Paternoster, Emanuele Torri, Marcello Bertotti

“…Results Findings are presented showing the ecosystem dynamics at each intervention phase: the referral process, co-production of an individualized action plan, and connection with and activation of community assets. …”
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An updated regional model skill assessment for seasonal and interannual variability of bottom temperature across the eastern Bering Sea shelf by Kelly A. Kearney, Phyllis J. Stabeno, Albert J. Hermann, Albert J. Hermann, Calvin W. Mordy, Calvin W. Mordy

“…Overall, this paper presents the most detailed spatiotemporal analysis of this model’s skill in simulating bottom temperature across the eastern Bering Sea shelf to date and supplies a benchmark analysis framework that can be used for planned regional model transitions and improvements over the coming years.…”
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Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre... by Marcus Green, Chao Wang, Sarah Fisher, Amarnath Bhide, Ramesh Ganapathy, Basky Thilaganathan, Nouran Elbarbary

“…Two follow-up visits are planned at 2 and 4 weeks after the initial recruitment where repeat testing with both tests will be performed. …”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Sex, age category/ART regimen core agent (combined variable), time since ART initiation and district were independently associated with viraemia.Future plans VICONEL offers potential for (1) further digitalisation and automation of results sharing at the client, facility and district/national level, (2) integration of additional clinical and diagnostic data, including comorbidities and drug resistance and (3) embedding randomised trials.…”
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Genetic markers of children asthma: predisposition to disease course variants by M. V. Smolnikova, Ed. W. Kasparov, M. A. Malinchik, K. V. Kopylova

“…The results obtained will supplement information on the prevalence of polymorphic variants of the cytokine genes in the Russian population and in asthma patients with different disease courses, which is likely to be used in order to shape a plan for Public Health Authority to prevent the development of severe uncontrolled asthma and to optimize personalized therapy.…”
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Heat-related mortality in Mexico: A multi-scale spatial analysis of extreme heat effects and municipality-level vulnerability by Lara Schwarz, Chen Chen, Javier Emmanuel Castillo Quiñones, L.C. Aguilar-Dodier, Kristen Hansen, Jaime Reyes Sanchez, David J.X. González, Gordon McCord, Tarik Benmarhnia

“…Understanding the differential risks of extreme heat events at varying scales is important to prioritize at-risk populations in action plans and policies to reduce their burden.…”
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Thermal Response and Degressive Reaction Study of Oxo-Biodegradable Plastic Products Exposed to Various Degradation Media by S. M. Al-Salem, A. Y. Al-Nasser, M. H. Behbehani, H. H. Sultan, H. J. Karam, M. H. Al-Wadi, A. T. Al-Dhafeeri, Z. Rasheed, M. Al-Foudaree

“…This work also paves the way for developing national standards and future plans for societies burdened with PSW accumulation.…”
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Severe pneumonia caused by Nocardia otitidiscaviarum in a patient with bronchiectasis and IgA nephropathy: a case report by Yi Lin, Zhao-Zhao Jiang, Xiao-Qian Chi, Jian-Sheng Chen, Chao Wen, Chao Zhang, Ying-Ying Wang, Guang-Liang Xie

“…Appropriate bacterial culture methods and efficient identification techniques should be adopted to promptly identify pathogens, and personalized treatment plans should be developed based on antibiotic sensitivity tests to save patients’ lives.…”
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Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China by Ziyang Liu, Davide Cammarano, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…For different regions, we have proposed management and breeding plans to make winter wheat better adapted to future changes in GDD. …”
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A deep learning algorithm to generate synthetic computed tomography images for brain treatments from 0.35 T magnetic resonance imaging by Luca Vellini, Flaviovincenzo Quaranta, Sebastiano Menna, Elisa Pilloni, Francesco Catucci, Jacopo Lenkowicz, Claudio Votta, Michele Aquilano, Andrea D’Aviero, Martina Iezzi, Francesco Preziosi, Alessia Re, Althea Boschetti, Danila Piccari, Antonio Piras, Carmela Di Dio, Alessandro Bombini, Gian Carlo Mattiucci, Davide Cusumano

“…Intensity Modulated Radiation Therapy (IMRT) plans were optimised on simulation MRI and calculated considering sCT and original CT as electron density (ED) map. …”
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Evaluation of a mentorship matchmaking event at an academic research institution to reinforce the scientific workforce pathway for underrepresented minority groups by Sirena Gutierrez, Jennifer A. Seuferer, Angel-Max Guerrero, Yazmin Carrasco, Kirsten Bibbins-Domingo, Tung Nguyen, Leticia Márquez-Magaña, Todd Nystul, Meghan D. Morris

“…Most mentor participants established at least one mentor-trainee connection after the event (n = 64, 57%), a mentor-trainee research experience match (n = 40, 35%), and planned to submit an NIH diversity supplement (n = 31, 27%). …”
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A new phase of China-ASEAN health cooperation: the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies by Jie Qiao, Siyan Zhan, Minghui Ren, Haijun Wang, Yangmu Huang, Zhenyu Zhang, Yanan Luo, Hui Yin, Zhongwei Jia, Wei Huang, Hong Zhou, Jue Liu, Xiaoyun Liu, Qiudan Sun, Xiaojia Li, Jing Bai, Fangjing Liu, Yihong Liu, Yinzi Jin, Ming Xu, on behalf of China-ASEAN Science and Technology Cooperation Center for Public Health

“…The Center held the Second Annual Forum on China-ASEAN Cooperation in Public Health on June 26–28, 2024, and the participants reached consensus on launching the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies, which calls on China and ASEAN countries to carry out the following actions: (1) Establish a more effective, open, and inclusive cooperation mechanism for health product innovation towards a China-ASEAN innovation ecosystem; (2) Enhance R&D capabilities by targeting new technologies, methods and appropriate and affordable health products for key populations and addressing diseases prevalent in China and ASEAN; (3) Establish a China-ASEAN Collaboration Center for Health Product Innovation, coordinate regional development plans, and enhance equitable access to pharmaceutical products at the regional level; (4) Accelerate regulatory harmonization in the region by optimizing and improving regulatory modalities of China and ASEAN Countries; and (5) Strengthen cross-sectoral cooperation to build resilient health system and achieve sustainable development of innovation cooperation. …”
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Application of an integrated behaviour-change model on grandparental adherence towards childhood domestic injury prevention in Hong Kong: a longitudinal study by Martin S Hagger, Patrick Ip, Derwin King Chung Chan, Roni Man Ying Chiu, Catherine M Capio, Patrick S H Yung, Agnes Y K Lai

“…In this study, we investigated the motivational and belief processes underlying childhood domestic injury prevention in grandparent caregivers based on the integrated model of self-determination theory and theory of planned behaviour.Method Grandparents (n=299, mean age=62.61 years, SD=5.91, men=20.07%) of 0–2-year-old infants and toddlers self-reported their perceived psychological need support, autonomous motivation, perceived behavioural control (PBC), subjective norms, attitude, intention and adherence with regard to domestic injury prevention for their children at two time points (T1: baseline, T2: 4-month follow-up).Results/outcomes Data were analysed with structural equation modelling, and the proposed model yielded an acceptable fit with the data: χ2=905.09 (df=531), Comparative Fit Index=0.94, Tucker-Lewis Index=0.93, root mean square error of approximation=0.05 and standardised root mean square residual=0.078. …”
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Clinical Validation of the Defining Characteristics of the Nursing Diagnosis ‘Activity Intolerance’ in Patients With Acute Coronary Syndrome by Diana Isabel Cáceres Rivera, Luz Mileyde Jaimes Rojas, Luisa Yaneth Cristancho Zambrano, Jennifer Vanesa Acosta Barón, Diana Ivonne Cañon Gómez, Lyda Z. Rojas

“…This discovery offers crucial insights for devising individualised and collective care plans within coronary units.…”
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