Efficacy and Safety of Iguratimod for the Treatment of Rheumatoid Arthritis by Jiangtao Li, Hejuan Mao, Yan Liang, Yanrong Lu, Shuo Chen, Nanping Yang, Guixiu Shi

“…Meta-analyses showed that, after 24-week therapy, ACR20, tender joint count, swollen joint count, rest pain, physician and patient global assessment of disease activity, HAQ score, ESR, and CRP in iguratimod group were better than those in placebo group and that the difference between those of iguratimod group and those of other DMARDs (MTX and SASP) group was not significant. …”
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Evaluation of Urinary Tract Infection following Corticosteroid Therapy in Patients with Multiple Sclerosis Exacerbation by Aliyeh Bazi, Seyed Mohammad Baghbanian, Monireh Ghazaeian, Sahar Fallah, Narjes Hendoiee

“…Patients were randomly split into two groups: oral prednisolone and placebo (tapering for 20 days). Demographic data, duration of multiple sclerosis, urinary tract symptoms, the Expanded Disability Status Scale (EDSS) score, and urine data were analyzed. …”
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A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women by Elena Benelli, Scilla Del Ghianda, Caterina Di Cosmo, Massimo Tonacchera

“…We enrolled 46 patients affected by PCOS and, randomly, we assigned them to two groups, A and B, treated, respectively, with the association of MI plus DCI, in a 40 : 1 ratio, or with placebo (folic acid) for six months. Thus, we analyzed pretreatment and posttreatment FSH, LH, 17-beta-Estradiol, Sex Hormone Binding Globulin, androstenedione, free testosterone, dehydroepiandrosterone sulphate, HOMA index, and fasting glucose and insulin. …”
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The temporal relationship between the neural and vascular actions of kallidin within the nose by K. Rajakulasingam, L. C. K. Lau, R. Polosa, M. K. Church, S. T. Holgate, P. H. Howarth

“…[des-arg9]-Bradykinin and vehicle placebo (V) were without effect on any of these indices. …”
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Comparison of Dexmedetomidine with Acetaminophen and Its Combination (Apodex) on Pain Control, Emergence Agitation and Delirium in Pediatric Patients Undergoing Adenotonsillectomy... by farzad sarshivi, negin ghadami, karim naseri, soraya sarshivi

“…The fourth group received (50 ml) normal saline as a placebo intravenously within 15 minutes before the end of surgery. …”
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The Effect Of Percussive Therapy On Musculoskeletal Performance And Experiences Of Pain: A Systematic Literature Review by Lorna Sams, Ben L Langdown, Joan Simons, Jitka Vseteckova

“… # Methods Data sources (CINAHL, Cochrane Library, Psychinfo, PubMed, SportDISCUS and OpenGrey) were searched from January 2006 onwards for full text literature in any language involving adult populations receiving PT delivered by massage guns, directly to any muscle belly or tendon, with comparisons to an alternative treatment, placebo or no treatment. Literature with outcomes relating to acute or chronic physiological adaptations in muscle strength, explosive muscle strength, flexibility or experiences of musculoskeletal pain were included. …”
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Palmitoylethanolamide, a Natural Retinoprotectant: Its Putative Relevance for the Treatment of Glaucoma and Diabetic Retinopathy by Jan M. Keppel Hesselink, Ciro Costagliola, Josiane Fakhry, David J. Kopsky

“…PEA has been tested in at least 9 double blind placebo controlled studies, among which two studies were in glaucoma, and found to be safe and effective up to 1.8 g/day, with excellent tolerability. …”
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Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation by Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye

“…Our review demonstrates that bupropion is superior to placebo and non-inferior to SSRIs such as escitalopram in treating major depressive disorder. …”
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Update on the therapeutic role of metformin in the management of polycystic ovary syndrome: Effects on pathophysiologic process and fertility outcomes by Kerstin MG Brand, Ulrike Gottwald-Hostalek, Aimee Andag-Silva

“…The metabolic action of metformin involves amelioration of insulin resistance, which helps to resolve hormonal and metabolic disturbances and increases ovulation, pregnancy, and live birth rates relative to placebo. A combination of metformin with clomifene citrate (another widely used treatment for PCOS) is more effective than either alone and is a useful option in women with clomifene-resistant PCOS. …”
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Statins—Their Effect on Lipoprotein(a) Levels by Marcin Mateusz Granat

“…Only randomised control studies and studies with a placebo/comparator arm were included. For calculations, SPSS Statistics software version 29 was used. …”
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High Salt Intake Increases Copeptin but Salt Sensitivity Is Associated with Fluid Induced Reduction of Copeptin in Women by Irina Tasevska, Sofia Enhörning, Philippe Burri, Olle Melander

“…In addition to meals containing 50 mmol NaCl daily, capsules containing 100 mmol NaCl and corresponding placebo capsules were administered during 4 weeks each, in random order. …”
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Use of NSAIDs via the Rectal Route for the Prevention of Pancreatitis after ERCP in All-Risk Patients: An Updated Meta-Analysis by Lei-Min Yu, Ke-Jia Zhao, Bin Lu

“…We searched database for randomized controlled trials (RCTs) comparing periprocedural rectal administration of NSAIDs with placebo for the prevention of PEP. The rectal administration of NSAIDs significantly decreased the incidence of PEP in the whole patient population (odds ratio (OR): 0.44, 95% confidence interval (CI): 0.30–0.64, P<0.0001), high-risk patients (OR: 0.34, 95% CI: 0.19–0.58, P=0.0001), and all-risk patients (OR: 0.51, 95% CI: 0.31–0.84, P=0.008). …”
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Evaluación de la fotobiomodulación vascular en niños con bruxismo del sueño: un ensayo clínico aleatorizado y controlado by Natalia Osorio Viarengo, Sandra Kalil Bussadori

“…Los participantes se dividieron en grupo control (GC) con FBM placebo y terapia miofuncional orofacial (TMF), y grupo de fotobiomodulación (GF) con FBM activa y los mismos ejercicios. …”
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Effect of Low-Dose (Single-Dose) Magnesium Sulfate on Postoperative Analgesia in Hysterectomy Patients Receiving Balanced General Anesthesia by Arman Taheri, Katayoun Haryalchi, Mandana Mansour Ghanaie, Neda Habibi Arejan

“…Aparallel, randomized, double blinded, placebo-controlled trial study was designed to assess the efficacy of single low dose of intravenous magnesium sulfate on post-total abdominal hysterectomy (TAH) pain relief under balanced general anesthesia. …”
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Homeopathic Preparations to Control the Rosy Apple Aphid (Dysaphis plantaginea Pass.) by Eric Wyss, Lucius Tamm, Joachim Siebenwirth, Stephan Baumgartner

“…Controls were aqueous solutions of placebo granules or pure water. In eight independent, randomized, and blinded experiments under standardized conditions in growth chambers, the development of aphids on treated and untreated apple seedlings was observed over 17 days, each. …”
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A New Combination Formula for Treatment of Fungal Keratitis: An Experimental Study by Hala Mohamed El-Mofty, Mohamad Amr Salah Eddin Abdelhakim, Mohamed Farid El-Miligi, Mohamed A. El-Nabarawi, Islam Ahmed Hamed Khalil

“…The right eye for one subgroup received ketoconazole as control 1 while the other subgroup received placebo as control 2. Clinical follow-up was done and, finally, the corneas were used for microbiological and pathological evaluation. …”
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Ultrasound and 3D Skin Imaging: Methods to Evaluate Efficacy of Striae Distensae Treatment by Mariella Bleve, Priscilla Capra, Franca Pavanetto, Paola Perugini

“…The controlateral area with stretch marks was treated with a “placebo” formulation without active, as a control. …”
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Medicines for the management of overweight and obesity: A systematic review with network meta-analysis by Gabriela Masiero Marcon, Jhonatan Mendes Paiva, Mariana Delariva Sakiyama, Fernanda Stumpf Tonin, Fernando Fernandez-Llimos, Suzane Virtuoso, Andreia Cristina Conegero Sanches

“…The network meta-analysis revealed that all the treatments were significantly more effective than the placebo in weight reduction. The use of semaglutide (especially 0.4 mg/day) was associated with a bigger weight loss in comparison to all the other treatments (p<0.05) and the analysis of SMAA showed a risk-benefit of 95%. …”
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Self-Rated Recovery and Mood Before and After Resistance Training and Muscle Microcurrent Application by Bernd A. C. Stößlein, Kim P. C. Kuypers

“…The present study aimed to test the effects of RT and muscle-microstimulation on mood and physical recovery in healthy men after performing conventional deadlifts, which is a type of RT.MethodsThe study was conducted according to a single-blind, randomized, placebo-controlled, and two-way crossover study. Twenty participants naïve to microstimulation (MS) engaged in RT twice on separate days. …”
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