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121
A Large PROP1 Gene Deletion in a Turkish Pedigree
Published 2018-01-01“…Pituitary-specific paired-like homeodomain transcription factor, PROP1, is associated with multiple pituitary hormone deficiency. …”
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122
Malignant Lymphoma in the Parasellar Region
Published 2014-01-01“…The entity of pituitary (sellar or parasellar) lymphoma includes primary pituitary lymphoma (PPL) and secondary pituitary lymphoma (SPL). …”
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123
DIABETES INSIPIDUS: LITTLE-KNOWN FACTS
Published 2019-06-01“…The most common causes of diabetes insipidus are neurosurgical operations on the pituitary gland due to its defeat by benign and malignant tumors, the neoplasms themselves, lymphocytic hypophysitis. …”
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124
Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion
Published 2012-01-01“…This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache.…”
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125
X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women
Published 2025-02-01“…Abstract The incidence of pituitary adrenocorticotropic hormone (ACTH)-secreting PitNETs, commonly known as ACTH PitNETs, is significantly higher in females; however, the underlying causes for this gender disparity remain unclear. …”
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126
Acromegaloid gigantism. Case presentation
Published 2022-02-01“…Gadolinium-enhanced MRI reported pituitary macroadenoma. It was diagnosed as acromegaloid gigantism due to a growth hormone-producing pituitary tumor. …”
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127
Single-cell and spatial transcriptomics in endocrine research
Published 2024-02-01“…Endocrine organs also exhibit cellular heterogeneity and comprise multiple cell types. For instance, the pituitary gland comprises five types of pituitary hormone-producing cells as well as non-hormone-producing supporting cells, such as fibroblasts, endothelial cells, and folliculostellate cells. …”
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128
Septooptic Dysplasia with an Associated Arachnoid Cyst
Published 2016-01-01“…Magnetic resonance imaging of the brain confirmed the known history of arachnoid cyst with hydrocephalus but also revealed anterior pituitary hypoplasia, absence of the posterior pituitary bright spot, a thin pituitary stalk, and bilateral optic nerve hypoplasia. …”
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129
Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism
Published 2015-01-01“…The diagnosis of central hypothyroidism is often suspected in patients with hypothalamic/pituitary pathology, in the setting of low, normal, or even slightly elevated serum TSH and low free thyroxine (FT4). …”
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130
Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies
Published 2018-01-01“…Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is the cause of primary adrenal insufficiency, while secondary adrenal insufficiency is a result of pituitary or hypothalamic disease. …”
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131
Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient
Published 2018-01-01“…The hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-gonadal (HPG) axis are very sensitive and can be affected by external factors like stress, starvation, and medication. …”
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132
Traumatic Brain Injury and Hypopituitarism
Published 2005-01-01“…Patients with TBI should be screened both prospectively and retrospectively for isolated, multiple and even total pituitary deficits. It is well known that, patients with “classical” hypopituitarism (due to primary hypothalamic-pituitary pathologies) do benefit from hormonal replacement therapy. …”
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133
What is known and unknown about the role of neuroendocrine genes Ptprn and Ptprn2
Published 2025-01-01“…The protein tyrosine phosphatase receptors N and N2 are encoded by the Ptprn and Ptprn2 genes expressed in neuroendocrine cells of the hypothalamus, pituitary gland, and diffuse neuroendocrine system, including the pancreas, lung, and intestine. …”
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134
Germinoma with Involvement of Midline and Off-Midline Intracranial Structures
Published 2014-01-01“…Brain MRI showed a solid mass involving pituitary and hypothalamus with thickening of pituitary stalk, high intensity lesions on T2-weighted imaging in left internal capsule, caudate nucleus, globus pallidus, and mild atrophy of the left internal capsule and cerebral peduncle. …”
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135
Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article
Published 2025-01-01“…It has frequently been linked with dysfunction in the hypothalamic pituitary-adrenal axis (HPA). Increased cortisol or cortisolemia is evident throughout the acute phase, along with changes in the hypothalamic pituitary thyroid (HPT) axis, growth hormone-IGF-1 axis, insulin-glucose axis, leptin, catecholamines, renin angiotensin aldosterone axis, ghrelin, glucagon, hypothalamic pituitary gonadal (HGA) axis, and fibroblast growth factor-21. …”
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136
A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons
Published 2025-02-01“…In birds, leptin is expressed in the brain, pituitary glands, and gonads, where it enhances ovarian function and egg-laying performance, particularly during feed deprivation. …”
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137
Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview
Published 2013-01-01“…Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data, most authors do not recommend treatment and long-term followup in subjects with macroprolactinemia. …”
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138
Immunohistochemistry for (Pro)renin Receptor in Humans
Published 2021-01-01“…In the brain, (pro)renin receptor staining was detected in neurons throughout all areas, especially in the medulla oblongata, paraventricular nucleus and supraoptic nucleus of the hypothalamus, cerebrum, granular layer of the hippocampus, Purkinje cell layer of the cerebellum, and the pituitary anterior and posterior lobes. In the anterior lobe of the pituitary gland, all types of anterior pituitary hormone-positive cells showed double staining with (pro)renin receptor. …”
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139
Androgen Receptor Gene CAG Repeat Polymorphism Regulates the Metabolic Effects of Testosterone Replacement Therapy in Male Postsurgical Hypogonadotropic Hypogonadism
Published 2013-01-01“…Cardiovascular risk factors (CVRFs), pituitary-dependent hormones, and AR gene CAG repeat polymorphism were considered. …”
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140
Systemic Sarcoidosis Unmasked by Cushing’s Disease Surgical Treatment
Published 2016-01-01“…We report a case of sarcoidosis after the resection of an ACTH secreting pituitary adenoma.…”
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