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661
Uncovering the Heterogeneity of Signaling Pathways in Skin Cutaneous Melanoma: Insights into Prognostic Values and Immune Interactions
Published 2025-01-01“…However, functional heterogeneity of signaling pathways in skin cutaneous melanoma (SKCM) has not been established.Methods: Based on a recent computational pipeline, pathway activities between SKCM and normal samples were identified.Results: The results showed that high activities in 12 pathways were associated with poor prognoses, while high activities in 17 pathways were associated with favorable prognoses. …”
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662
Clustering Large-Scale Biomedical Data to Model Dynamic Accumulation Processes in Disease Progression and Anti-Microbial Resistance Evolution
Published 2025-01-01“…We demonstrate this ‘Cluster-based HyperHMM’ (CHyperHMM) pipeline for synthetic data, clinical data on disease progression in severe malaria, and genomic data for anti-microbial resistance evolution in Klebsiella pneumoniae, reflecting two global health threats.…”
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663
Bringing Motor Imagery BCI systems outside of the laboratory into daily activities
Published 2025-03-01“…This research aims to bridge the gap between laboratory and real-world applications by addressing key challenges at every stage, across the MI-BCI pipeline. Enhanced training methods using Virtual Reality(VR) were shown to significantly improve signal quality, as demonstrated in a study involving 21 participants. …”
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664
Machine Learning-Assisted Drug Repurposing Framework for Discovery of Aurora Kinase B Inhibitors
Published 2024-12-01“…<b>Methods:</b> This study introduces a machine learning-assisted drug repurposing framework integrating quantitative structure-activity relationship (QSAR) modeling, molecular fingerprints-based classification, molecular docking, and molecular dynamics (MD) simulations. Using this pipeline, we analyzed 4680 investigational and approved drugs from DrugBank database. …”
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665
Attention‐Based Machine Vision Models and Techniques for Solar Wind Speed Forecasting Using Solar EUV Images
Published 2022-03-01“…Our analysis shows that attention‐based models combined with our pipeline consistently outperform convolutional alternatives. …”
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666
Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer’s disease
Published 2025-02-01“…Here, we deployed a recent cell-type mapping pipeline, Matrix Inversion and Subset Selection (MISS), to determine the brain-wide distributions of pan-hippocampal and neocortical cells in the mouse, and then used these maps to identify general principles of cell-type-based selective vulnerability in PS19 mouse models. …”
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667
Linguistic Analysis of Hindi-English Mixed Tweets for Depression Detection
Published 2022-01-01“…In the proposed model pipeline, composed techniques are used to get the better results, as 96.15% accuracy and 0.914 as the F1 score have been attained.…”
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668
The D126G mutation contributes to the early-onset X-linked juvenile retinoschisis
Published 2025-01-01“…The understanding of the genotype-phenotype relationship and the pathomechanisms of specific mutations in a particular population could immensely benefit the pipeline of personalised treatment design for XLRS.…”
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669
Automated Tree Detection Using Image Processing and Multisource Data
Published 2025-01-01“…We developed a data pipeline for gathering and pre-processing information, including vegetation data and numerical land-cover models, which were used to derive a new method for tree detection. …”
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670
Performance evaluation of the SM4 cipher based on field‐programmable gate array implementation
Published 2021-03-01“…The results show that the best scalar implementation utilises less resources than the pipelined implementations by 7%. Alternatively, pipelined implementations perform better regarding speed and energy dissipation by 10 times and 40% of the scalar implementation, respectively. …”
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671
Effects of pH, Temperature, Dissolved Oxygen, and Flow Rate on Phosphorus Release Processes at the Sediment and Water Interface in Storm Sewer
Published 2013-01-01“…The cumulative amount of P release increased with the process of pipeline runoff in the rainfall events with high intensities and shorter durations. …”
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672
MLHOps: Machine Learning Health Operations
Published 2025-01-01“…This work therefore provides guidance across the full pipeline of MLHOps from conception to initial and ongoing deployment. …”
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673
Deformation and Damping Characteristics of Lightweight Clay-EPS Soil under Cyclic Loading
Published 2018-01-01“…., soft ground improvement, the solvent of bridge head jump, earthfill of pipeline, and broadening of highway. Meanwhile, construction castoff and industrial waste can be recycled as a major ingredient in LCES. …”
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674
Facilitating high throughput bispecific antibody production and potential applications within biopharmaceutical discovery workflows
Published 2024-12-01“…Four bsAb products were granted first regulatory approvals in the US or EU during 2023 and the biopharmaceutical industry pipeline is brimming with bsAb candidates across a broad range of therapeutic applications. …”
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675
Sustainable Selection of Machine Learning Algorithm for Gender-Bias Attenuated Prediction
Published 2025-01-01“…Using data devoid of biometric and geographic information, the proposed pipeline distinguishes manifested binary genders with 80% accuracy for the drivers in the holdout data set. …”
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676
An Improved Composite Fly Ash Gel to Extinguish Underground Coal Fire in Close Distance Coal Seams: A Case Study
Published 2020-01-01“…The grouting technical scheme of adding a suspending agent on the ground and gelling agent downhole was proposed to solve the problems of solid material settlement and blockage in the long-distance pipeline transportation process. Finally, the optimized fly ash colloid fire prevention and extinguishing technology was successfully applied to the fire control engineering examples of close-range coal seam groups, and the rationality of the developed powder and its proportion was tested, and the feasibility in coal fire control was tested.…”
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677
Eight New Candidate Multiplanet Systems among TESS Objects of Interest
Published 2025-01-01“…We perform a Box Least Squares search on light curves prepared by the Quick-Look Pipeline to recover known candidates and perform a targeted search for additional candidates in each system. …”
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678
Unveiling microbial communities with EasyAmplicon: A user‐centric guide to perform amplicon sequencing data analysis
Published 2024-12-01“…To address this challenge, in 2023 we developed EasyAmplicon, a comprehensive, user‐friendly pipeline that integrates popular tools such as USEARCH and VSEARCH, offering a streamlined workflow from raw data to results. …”
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679
Identification of PET/CT radiomic signature for classification of locally recurrent rectal cancer: A network-based feature selection approach
Published 2025-01-01“…The efficiency of the pipeline in predicting LRRC was evaluated according to the sensitivity, specificity, Balanced Accuracy Score (BAS) and Matthews's Correlation Coefficient (MCC). …”
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680
Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing
Published 2025-02-01“…Signatures of lower respiratory tract microbiome were compared between groups using an exact k-mer matching metagenomic analysis pipeline (Kraken 2) and a metagenome-assembled genomes pipeline (MetaWRAP). …”
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