Feasibility Study of the Time Reversal Symmetry Tests in Decay of Metastable Positronium Atoms with the J-PET Detector by A. Gajos, C. Curceanu, E. Czerwiński, K. Dulski, M. Gorgol, N. Gupta-Sharma, B. C. Hiesmayr, B. Jasińska, K. Kacprzak, Ł. Kapłon, D. Kisielewska, G. Korcyl, P. Kowalski, T. Kozik, W. Krzemień, E. Kubicz, M. Mohammed, Sz. Niedźwiecki, M. Pałka, M. Pawlik-Niedźwiecka, L. Raczyński, J. Raj, Z. Rudy, S. Sharma, Shivani, R. Shopa, M. Silarski, M. Skurzok, W. Wiślicki, B. Zgardzińska, M. Zieliński, P. Moskal

“…Two possible strategies of searching for manifestations of T violation in nonvanishing angular correlations of final state observables in the decay of metastable triplet states of positronium available with J-PET are proposed and discussed. Results of a pilot measurement with J-PET and assessment of its performance in reconstruction of three-photon decays are shown along with an analysis of its impact on the sensitivity of the detector for the determination of T-violation sensitive observables.…”
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Des vestiges d’un possible aqueduc à Lyon, à l’angle des rues Appian et des Fossés-de-Trion by Tony Silvino

“…On the other hand, if these structures were part of an aqueduct, trench F112 might simply be a possible siphon earthwork, either a mistake, a temporary trench or a pilot structure, built in advance to assess the possibility of the aqueduct.Ultimately, the hypothesis that there was an aqueduct in this area during the reign of Augustus is viable, though it should treated with caution since the traces are quite sparse. …”
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The HFA‐PEFF score identifies ‘early‐HFpEF’ phenogroups associated with distinct biomarker profiles by Michiel T.H.M. Henkens, Anne‐Mar vanOmmen, Sharon Remmelzwaal, Gideon B. Valstar, Ping Wang, Job A.J. Verdonschot, Mark R. Hazebroek, Leonard Hofstra, Vanessa P.M. vanEmpel, Joline W.J. Beulens, Hester M. denRuijter, Stephane R.B. Heymans

“…Whether the HFA‐PEFF domain scores can identify ‘early‐HFpEF’ phenogroups remains unknown. The aims of this pilot study are to (i) identify distinct phenogroups by cluster analysis of HFA‐PEFF domain scores in subjects that present with HF‐like symptoms and (ii) study whether these phenogroups may be associated with distinct blood proteome profiles. …”
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Design and validation of a questionnaire on habits, health and exercise in the use of baby carriers by Yaiza Taboada-Iglesias, María del Carmen Iglesias-Pérez, Águeda Gutiérrez-Sánchez

“…Material and methods: 350 individuals who currently used or had used baby carrying systems in the last 10 years completed the questionnaire, which was previously subject to a pilot study in a panel of experts. We used exploratory factor analysis to assess the validity of the internal structure of the questionnaire. …”
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Knowledge towards health impacts of climate change among Amhara Sayint community, Northeastern Ethiopia by Genanew Mulugeta Kassaw, Asmamaw Malede, Adinew Gizeyatu, Metadel Adane, Asha Embrandiri, Awoke Keleb, Gete Berihun, Abebe Kassa Geto, Belachew Tekleyohannes Wogayehu, Gebremeskel Kibret Abebe, Tibebu Habtie Zewde, Sisay Abebe Debela, Solomon Seyoum, Amana Ogeto Luke, Gashaw Wondaya, Atitegeb Abera Kide, Mekonnen Moges, Denise Metoyer, Mesfin Gebrehiwot

“…Data were collected through face-to-face interviews using a pilot-tested and content-validated questionnaire administered via Kobo Collect survey tool. …”
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Implementation of patient-reported outcome dashboards within the electronic health record to support shared decision-making in serious chronic illness by Glyn Elwyn, Sheetal M Kircher, Eugene Nelson, David Cella, Lisa Hirschhorn, Cynthia Barnard, Vikram Aggarwal, Jeffrey Linder, Sofia F Garcia, Aricca Van Citters, Mary O'connor, Laura M Perry, Nisha A Mohindra, Ava Coughlin, Katy Bedjeti, Devin Peipert, Melissa Weitzel, Victoria Morken, Elijah Patten, Jissell Torres, Susan Metzger, Alesia O’daniel, Ryan Chmiel, Reena Modi, Michelle Munroe, Stavroula Xinos

“…Most patients (77%) and clinicians (86%) valued the dashboard for increasing SDM, and 57% of clinicians endorsed the dashboard’s clinical sustainability.Discussion This pilot study demonstrated the clinical appropriateness, acceptability and feasibility of implementing an EHR-integrated PRO dashboard for advanced cancer and chronic kidney disease. …”
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Prevalence of peptic ulcer disease and its associated factors in Jeddah Saudi Arabia by Muazzam Sheriff Maqbul, Reem Saleh Alzaki, Reema Sami Meeralam, Norah Abdulmajeed Alqutami, Bayan Mohammed Alturki, Lina Sultan Alhazmi, Reem Mamdouh Alaseeri, Lama Saad Alghamdi, Reem Khalid bin Brik, Shaima Tariq Mansoor Beig, Muath Saeed Alamri, Wjood Abdullah A. Alshehri, Turki Ayed Almutairi, Maha Abdullah Alqurashi, Ahmed Jamal Nasef

“…It was translated into Arabic, culturally adapted, and validated through expert review and pilot testing. A sample size of 561 participants was determined using an online sample calculator, targeting a 95 ​% confidence level. …”
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Evolution, Characteristics and Inspirations of Management Zoning for National Parks in the United States by Zhenwei ZHANG, Hanyue XIAO, Yankang MAO

“…Zoning is a crucial system for national park management and represents a significant scientific topic in national park management. From the pilot stage to a new development stage, how to scientifically and rationally conduct zoning in national parks, based on the “Chinese model”, still remains a scientific issue to be addressed. …”
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Mobile Toolbox sequences task: development and validation of a remote, smartphone-based working memory test by Jerry Slotkin, Aaron J. Kaat, Stephanie Ruth Young, Elizabeth M. Dworak, Miriam A. Novack, Yusuke Shono, Hubert Adam, Cindy J. Nowinski, Sarah Pila, Zahra Hosseinian, Maria Varela Diaz, Anyelo Almonte-Correa, Keith Alperin, Monica R. Camacho, Monica R. Camacho, Bernard Landavazo, Bernard Landavazo, Rachel L. Nosheny, Rachel L. Nosheny, Michael W. Weiner, Michael W. Weiner, Richard C. Gershon

“…The Sequences measure was evaluated for usability and feasibility across two pilot studies and then assessed in this validation study (which included a total sample size of N = 1,246). …”
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γ-亚麻酸对α-亚麻酸转化为DHA的影响 Effect of γ-linolenic acid on the conversion of α-linolenic acid to DHA by 谢婉菲1，姜珊1，王成成1，王玉明1,2，薛长湖1,2，张恬恬1 " XIE Wanfei1, JIANG Shan1, WANG Chengcheng1, WANG Yuming1,2, XUE Changhu1,2, ZHANG Tiantian1"

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Modified Bloom's Taxonomy: Perspective of a Doctor of Philosophy Scholar by Wafa Omer

“…It remains in text and the hardbound theses keep getting stacked in the storerooms of educational institutions as the scholars move on without even a pilot incorporation of their findings in the real workplace-based systems. …”
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PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label,... by David Taylor-Robinson, Steve Goodacre, Neil French, Richard Body, Kerenza Hood, Emma Thomas-Jones, Jane Daniels, Sarah Walker, Ingeborg Welters, Mike Bradburn, Paul Schmidt, Enitan Carrol, Lucy Brookes-Howell, Sarah Milosevic, Andrew Tabner, Philip Pallmann, Stephen Aston, Gavin Barlow, Emma Richards, Emmanuel Nsutebu, Philip Howard, Matthew Inada-Kim, Stacy Todd, Fiona McGill, Martin Llewelyn, Louis Wihelmus Niessen, Joanne Euden, Julie Carman, Stephanie Gilbert, Sam Clarkstone, Jacqui Hughes, Lena Meister, Angela Brain, Matthew Scarborough, Sian O'Shea, Claire James

“…The study has an internal pilot phase and group-sequential stopping rules for effectiveness and futility/safety, as well as a qualitative substudy and a health economic evaluation.Ethics and dissemination The trial protocol was approved by the Health Research Authority (HRA) and NHS Research Ethics Committee (Wales REC 2, reference 20/WA/0058). …”
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The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

“…Methods This is an online, two-arm, parallel-group superiority RCT with internal pilot phase. People aged ≥1 year with eczemaliving in the United Kingdom are eligible. …”
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Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within... by Deborah D Stocken, Charles H Knowles, Jared Torkington, David Jayne, Julie Hepburn, Laura Knight, Neil Corrigan, Julie Cornish, Katie Gordon, Ashley Douglas, Kate Wilson, Megan Dale, Julie Croft, Christina Lloydwin, Alexandra Harriet Coxon-Meggy, Judith White, Alun Meggy, Aaron Quyn, Emily Farrow, Kheng-Seong Ng, Hannah Mather, Huey Yi Chong, Betty Tan, Ralph Powell, Andrea Warwick

“…Despite this, little is known about the natural history and there is poor evidence to support current treatment options.Methods and analysis The objectives of POLARiS are to explore the natural history of LARS and to evaluate the clinical and cost-effectiveness of transanal irrigation (TAI) or sacral neuromodulation (SNM) compared with optimised conservative management (OCM) for people with major LARS.POLARiS is a prospective, international, open-label, multi-arm, phase 3 randomised superiority trial within a cohort design, with internal pilot phase, qualitative sub-study, process evaluation and economic evaluation. …”
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Mental health disorder symptom changes among public safety personnel after emotional resilience skills training by R.N. Carleton, S. Sauer-Zavala, T.A. Teckchandani, K.Q. Maguire, L. Jamshidi, R.E. Shields, T.O. Afifi, J. Nisbet, K.L. Andrews, S.H. Stewart, A.J. Fletcher, R. Martin, R.S. MacPhee, J.C. MacDermid, T.M. Keane, A. Brunet, M. McCarron, L.M. Lix, N.A. Jones, G.P. Krätzig, J.P. Neary, G. Anderson, R. Ricciardelli, H. Cramm, J. Sareen, G.J.G. Asmundson

“…The Royal Canadian Mounted Police (RCMP) Protocol was designed to mitigate PTSIs using ongoing monitoring and PSP-delivered Emotional Resilience Skills Training (ERST) based on the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders. The current study pilot-tested ERST effectiveness among diverse PSP. …”
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Rapid molecular assays versus blood culture for bloodstream infections: a systematic review and meta-analysisResearch in context by Gabriella Anna Rapszky, Uyen Nguyen Do To, Veronika Eszter Kiss, Tamás Kói, Anna Walter, Dorottya Gergő, Fanni Adél Meznerics, Márton Rakovics, Szilárd Váncsa, Lajos Vince Kemény, Dezső Csupor, Péter Hegyi, Michael R. Filbin, Csaba Varga, Bánk G. Fenyves

“…Two RMAs were included in the qualitative synthesis only (InfectID-BSI, Pilot Gene Technology droplet digital polymerase chain reaction). …”
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Evaluating the effectiveness of integrated traditional Chinese and Western treatment based on symptom grading: a study protocol for a multi-center, randomized controlled trial of p... by Jiaxi Mai, Tingwei Zhou, Tingwei Zhou, Tingwei Zhou, Chen Wang, Chen Wang, Junrong Ye, Junrong Ye, Jiao Chen, Jiao Chen, Jiao Chen, Wen Wang, Wen Wang, Wen Wang, Yuanxin Pan, Yuanxin Pan, Yuanxin Pan, Yanheng Wei, Yanheng Wei, Lexin Yuan, Lexin Yuan, Hang Yang, Hang Yang, Shengwei Wu, Shengwei Wu, Jianxiong Guo, Jianxiong Guo, Jianxiong Guo, Aixiang Xiao, Aixiang Xiao, Aixiang Xiao

“…The proposed study presents a pilot trial to evaluate the effectiveness of interventions at different levels in improving depression status in community populations.MethodsA randomized controlled trial will be conducted in two communities in Guangdong, China, with a follow-up period of 12 weeks. …”
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Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inf... by Holger Neb, Verena Roth, Jessica Roos, Jessica Roos, Tom Bauer, Anja Urbschat, Ulrike Heinicke, Carlo Angioni, Dieter Steinhilber, Dieter Steinhilber, Matthias Piesche, Matthias Piesche, Nerea Ferreirós, Robert Gurke, Robert Gurke, Gerd Geisslinger, Gerd Geisslinger, Edith Utech, Kai Zacharowski, Patrick Meybohm, Patrick Meybohm, Patrick Paulus, Elke Schmitt, Elke Schmitt, Thorsten Jürgen Maier, Thorsten Jürgen Maier

“…Furthermore, 6-keto-PGF1alpha had its peak shortly before initiation of continuous veno-venous hemodialysis (at least in 5 of the observed patients), 2-AG was elevated in all our nine patients during (right) heart failure in the context of either re-opening patient’s chest, implementation of veno-arterial ECMO or at least while significantly increasing the amount of catecholamines.DiscussionIn this pilot trial we identified several evaluated lipids in critically ill patients representing either potentially (patho-) physiologically relevant mediators of the pro-inflammatory processes and during heart failure or possible markers preceding veno-venous hemodialysis.…”
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How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland? by Florence Epiney, Siegfried Nagel, Christopher Klenk

“…A semi-structured interview guideline was developed, discussed with experts and tested in a pilot interview (Braun & Clarke, 2022; Smith & Sparkes, 2020). …”
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FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn... by Kerry Woolfall, Jamie J Kirkham, Jane Sandall, Mariana Popa, Enrico Lopriore, Mark Turner, Shakila Thangaratinam, Aris T Papageorghiou, Andrew Sharp, Lawrence Impey, Andy Healey, Jessica Mendoza, Asma Khalil, Dharmintra Pasupathy, Brigitte Vollmer, Zarko Alfirevic, Rajeswari Parasuraman, Jan Deprest, Richard Edmund Ashcroft, Kurt Hecher, Smriti Prasad, Baskaran Thilaganathan, Richard J Jackson, Tracy Karen Mitchell, Natasha Fenwick, Monique C Haak, Liesbeth Lewi, Shauna Leven, Fabricio Da Silva Costa, Odai Yaghi, Tracey Ricketts, George Attilakos, Carolyn Bailie, Christine Cornforth, Mark Denbow, Louise Hardman, Jane Harrold, Joel Marsden, Tommy Mousa, Surabhi Nanda, Michelle Watson, Karen Wilding, Dilly Anumba, Edward D Johnstone, Yoav Yinon, Ahmet Baschat

“…Based on previous similar pilot studies, this is anticipated to be approximately 15–25 interviews in both the parent and clinician groups. …”
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