A randomized controlled trial on the effect of smartphone-based mental health application among outpatients with depressive and anxiety symptoms: A pilot study in Malaysia by Sharon Tan, Mohammad Ayob Bin Ismail, Tuti Iryani Mohd Daud, Rozita Hod, Norfazilah Ahmad

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Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study by Yaser Masoumi-Ardakani, Mostafa Eghbalian, Hossein Fallah, Alireza Jafari, Beydolah Shahouzehi

“…Among these, miR-33a/b is particularly associated with metabolic diseases, notably obesity and atherosclerosis. In this pilot case-control study, 45 subjects were examined, and serum miR-33b levels were measured in three groups: a control group, hypercholesterolemic (HC) subjects without obesity (HC group), and obese subjects without hypercholesterolemia (obese group). …”
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Double-blind, randomized, placebo-controlled pilot clinical trial with gamma-band transcranial alternating current stimulation for the treatment of schizophrenia refractory auditory hallucinations by Xiaojuan Wang, Xiaochen Zhang, Yuan Chang, Jingmeng Liao, Shuang Liu, Dong Ming

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Fostering collaborative practice: a pilot study on interprofessional education through simulation-based team-oriented learning sessions among pharmacy and medical students by Shaimaa Khamis Mostafa, Rania H. Abdel-Rahman, Ahmed K. Mansour, Magda A. El-Sherbeny

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Effect of a high dose atorvastatin as adjuvant therapy to mesalamine in attenuating inflammation and symptoms in patients with ulcerative colitis: a randomized controlled pilot study by Sumaiah J. Alarfaj, Sahar M. El-Haggar, Sahar K. Hegazy, Sahar K. Hegazy, Maha M. Maher, Maha M. Maher, Monir M. Bahgat, Thanaa A. Elmasry, Sarah Alrubia, Amsha S. Alsegiani, Mostafa M. Bahaa

“…Activation of sphingosine 1 phosphate (S1P)/ tumor necrosis factor-alpha (TNF-α)/ interleukin-6 (IL-6) pathways has been confirmed in the pathogenesis of UC and preclinical studies proved the efficacy of atorvastatin on these pathways.AimTo investigate the role of atorvastatin on S1P/TNF-α/IL-6 pathway in UC.MethodsPatients with mild to moderate UC were allocated into two groups in this pilot study. For 6 months, Group 1 (placebo group) received both a placebo and 1 g of mesalamine three times daily (t.i.d.). …”
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Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study by Anna Persson, Anna Persson, Daniel Wallhed Finn, Alice Broberg, Amanda Westerberg, Åsa Magnusson, Åsa Magnusson, Olof Molander

“…Yet, there is a lack of knowledge on how to best treat co-occurring depression and alcohol use disorder. A pilot study was conducted to investigate the feasibility, credibility, patient satisfaction, preliminary effect, and potential negative effects of an integrated treatment for depression and alcohol use disorder, which has shown promising results in an earlier pilot trial.MethodsThe study was conducted at an outpatient unit in Stockholm, Sweden. …”
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Japi 2.0, a gaming platform to stimulate cognitive and non-cognitive skills in early childhood: protocol for a pilot randomized controlled trial by Jorge Gaete, Saray Ramírez, Cristian A. Rojas-Barahona, Valentina Romo, Natalia Ríos, Ricardo Araya

“…Pilot and Feasibility Studies…”
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Inerting Strategy for a Demonstration-Scale Hot Cell Facility Based on Experiences from Pilot-Scale Argon Cell Facility Operation and CFD Analysis by Seungnam Yu, Jaehoon Lim, Ilje Cho, Jonghui Han

“…Based on the successful operation of a pilot-scale facility, a conceptual design for this scale-up facility was actualized. …”
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Efficacy and safety of the first domestic pegilated interferon alpha-2b «Pegaltevir» at chronic hepatitis C: pilot data of phase III clinical study by V. T. Ivashkin, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, M. V. Mayevskaya, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda

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Early Effects of Hyperbaric Oxygen on Inducible Nitric Oxide Synthase Activity/Expression in Lymphocytes of Type 1 Diabetes Patients: A Prospective Pilot Study by Ivana Resanovic, Zoran Gluvic, Bozidarka Zaric, Emina Sudar-Milovanovic, Aleksandra Jovanovic, Davorka Milacic, Radmilo Isakovic, Esma R. Isenovic

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Author’s Response to Peer Reviews of “Converting Organic Municipal Solid Waste Into Volatile Fatty Acids and Biogas: Experimental Pilot and Batch Studies With Statistical Analysis” by Hojjat Borhany

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Rate of Perceived Exertion Based on Repetitions in Reserve Versus Percentage of One-Repetition Maximum for Resistance Training Prescription in Cardiac Rehabilitation: A Pilot Study by Alessandro Gismondi, Ferdinando Iellamo, Giuseppe Caminiti, Barbara Sposato, Emanuele Gregorace, Valentino D’Antoni, Deborah Di Biasio, Sara Vadalà, Alessio Franchini, Annalisa Mancuso, Valentina Morsella, Maurizio Volterrani

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Comparing the Efficacy of Transcutaneous Electric Nerve Stimulation (TENS) and Low Level Laser Therapy (LLLT) in the Management of Temporomandibular Joint Disorders: A Pilot Study by Vishalini Kalaivanan, Alex M. Muruppel, Angeline Deepthi, E. Gracelin Ranjitha, J. John Hearty Deepak, Kandasamy Murugan

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A Live Video Resiliency Dyadic Intervention for Persons With Dementia and Their Care-Partners Early After Diagnosis: Protocol for Open Pilot of Resilient Together for Dementia by Sydney McCage, Kristin Walker, Talea Cornelius, Robert A Parker, Kristen Dams-O'Connor, Brad Dickerson, Christine Ritchie, Ana-Maria Vranceanu, Sarah Bannon

“…ConclusionsWe will use these results to administer changes and develop procedures for a pilot feasibility trial of RT-ADRD relative to a minimally enhanced control condition. …”
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Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study by Peter P. Nghiem, Alexis M. Rutledge, Kyle Tehas, Corine Kaderli, Meredith Poling, Sidney Arnim, Vitaliy Dernov, Celine van Sas, Macie L. Mackey, Gabriella A. M. ten Have, Mariëlle P. K. J. Engelen, Nicolaas E. P. Deutz

“…Abstract Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease due to loss of dystrophin, leading to progressive muscle wasting and physical inactivity. In this pilot study, we studied the effect of daily supplementation of the anabolic substrate beta-hydroxy-beta-methylbutyrate (HMB) on whole body protein and amino acid kinetics using novel isotope methods and daily activity in a canine model of DMD. …”
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A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions by Mika Takasumi, Takuto Hikichi, Minami Hashimoto, Jun Nakamura, Tsunetaka Kato, Hitomi Kikuchi, Yuichi Waragai, Ko Watanabe, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Manabu Hayashi, Yuki Sato, Hiroki Irie, Ryoichiro Kobashi, Yoshinori Okubo, Masao Kobayakawa, Hiromasa Ohira

“…However, no studies have reported on the wet technique for EUS-FNA for gastrointestinal (GI) subepithelial lesions (SELs). We conducted a pilot randomized crossover trial to explore whether the wet technique could be useful with regard to tissue adequacy of upper GI-SELs (UGI-SELs) compared to the conventional EUS-FNA technique (“dry” technique). …”
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Enhancing balance and auditory function in bilateral vestibulopathy through otolithic vestibular stimulation: insights from a pilot study on cochlea-vestibular implant efficacy by Ángel Ramos-de-Miguel, Ángel Ramos-de-Miguel, Morgana Sluydts, Juan Carlos Falcón, Raquel Manrique-Huarte, Isaura Rodriguez, Andrzej Zarowski, Maurizio Barbara, Manuel Manrique, Silvia Borkoski, Joan Lorente, Marc Leblanc, Antonin Rambault, Erika Van Baelen, Carl Van Himbeeck, Alicia Huarte, Ángel Ramos Macías, Ángel Ramos Macías

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Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors by Dara L. James, Linda K. Larkey, Molly Maxfield, SeungYong Han, Edward Ofori, Alex E. Mohr, Nanako A. Hawley, Kate Alperin, Erica Ahlich, David E. Vance, Dorothy D. Sears

“…Methods: We conducted a single-group, pre-/post-pilot study to explore an 8-week prolonged nightly fasting intervention (14 h fasting/night) among adults 65+ years with self-reported memory decline. …”
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Can social pain be medicated away? A pilot study on everyday discrimination and its exacerbation of opioid misuse risk in people of color with chronic pain by Shin Ye Kim, Nguyen P. Nguyen, Yuki Shigemoto

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Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study by Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz

“…This retrospective pilot study aimed to detect whether remaining dental/periodontal treatment need and periodontal inflammation after dental clearance would be associated with the initial therapy outcome of adult patients with acute leukemia undergoing induction chemotherapy. …”
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