A network medicine approach to investigating ME/CFS pathogenesis in severely ill patients: a pilot study by Li-Yuan Hung, Chan-Shuo Wu, Chia-Jung Chang, Peng Li, Kimberly Hicks, Joshua J. Dibble, Braxton Morrison, Chimere L. Smith, Ronald W. Davis, Wenzhong Xiao

“…This pilot study harnessed the power of network medicine to unravel the complex pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). …”
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Multi-project wafer runs for electronic graphene devices in the European 2D-Experimental Pilot Line project by Bárbara Canto, Martin Otto, Arantxa Maestre, Alba Centeno, Amaia Zurutuza, Bianca Robertz, Eros Reato, Bartos Chmielak, Stefanie L. Stoll, Andreas Hemmetter, Florian Schlachter, Lisa Ehlert, Sha Li, Daniel Neumaier, Gordon Rinke, Zhenxing Wang, Max C. Lemme

“…To this end, the European Commission is supporting research toward establishing a European experimental pilot line for electronic and optoelectronic devices based on graphene and related two-dimensional (2D) materials, namely the Experimental Pilot Line (2D-EPL) project. …”
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Assessing the Impact of a Virtual Reality Cognitive Intervention on Tennis Performance in Junior Tennis Players: Pilot Study by Joaquin A Anguera, Aleem Choudhry, Michael Seaman, Dominick Fedele

“…Such a result warrants careful consideration, given the known difficulties in evidencing far transfer not only in cognitive studies but also in athletic activities. These preliminary pilot findings suggest that the Mastermind Cognitive Training program may be a viable tool for supplementing athletic training practices, although this result warrants further investigation and replication. …”
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Immunopathogenesis of inflammatory bowel diseases by Ye. A. Konovich, I. L. Khalif, M. V. Shapina

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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

“…Given the withdrawal-associated dysphoria and neurocognitive impairments characterising methamphetamine use disorder, ketamine-assisted psychotherapy may improve the efficacy of psychotherapy alone by addressing these features and facilitating therapeutic engagement. This pilot study aims to investigate the safety and feasibility (time taken to recruit sample, proportion of ineligible participants at pre-screening and screening, number of participants who complete four sessions of psychotherapy, retention rate over full duration of study, acceptability of the intervention) of subanaesthetic ketamine in combination with psychotherapy (cognitive behavioural therapy) for adults with methamphetamine use disorder. …”
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Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial by Sue F Plummer, Iveta Garaiova, Elizabeth A Williams, Bernard M Corfe, Simon Tazzyman, Nicholas Richards, Andrew R Trueman, Amy L Evans, Vicky A Grant

“…IBS symptoms were not significantly improved in this pilot, although a power calculation was enabled from the intervention data.Conclusions The IBS population exhibits significant levels of vitamin D insufficiency and would benefit from screening and possible supplementation. …”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…Differences between groups in serum inflammatory markers were detected at baseline and 3 days for interleukin (IL)-18, and at 10 days for IL-8.ConclusionPreliminary results from the present pilot study showed that steps 1 and 2 of periodontal treatment in subjects with periodontitis in stages III–IV and established cardiovascular disease induced improvements in cIMT and periodontal outcomes, although changes in FMD were not observed. …”
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The Perceptions of Overweight and Obese Individuals Regarding Weight-Loss Dietary Supplement Advertisements: A Pilot Cross-Sectional Survey by Nik Nur Anis Ilyany Zamzuri, Nor Elyzatul Akma Hamdan, Nurul Ashikin Jamludin, Mohammad Suhaidi Shaari, Nur Syazwani Taridi, Mohd Shahezwan Abd Wahab, Janattul Ain Jamal

“…Methods: Over a six-week period from 5th April to 17th May 2023, an online pilot cross-sectional study was conducted targeting overweight and obese individuals in Malaysia. …”
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Interdisciplinary Team Pilot to Reduce Time to Administration of Piperacillin/Tazobactam in the Emergency Department at a Veterans Affairs Medical Center by DiVittorio MM, Fisher T, Steadman B, Cone B, Elfessi Z

“…Eight patients died in the pre-pilot group compared to five in the post-pilot group. …”
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A pilot cluster randomized controlled trial assessing uptake of PrEP and contraception in hair salons in South Africa by Ingrid V. Bassett, Joyce Yan, Sabina Govere, Sthabile Shezi, Lungile M. Ngcobo, Shruti Sagar, Jana Jarolimova, Dani Zionts, Anele Khumalo, Zinhle Zwane, Christina Psaros, Nduduzo Dube, Robert A. Parker

“…Methods We conducted a pilot cluster randomized controlled trial to evaluate uptake of a hair stylist-initiated, nurse-supported intervention offering a dynamic choice of contraception (oral or injectable), STI testing and treatment, and oral PrEP in 3 salons in urban KwaZulu-Natal. …”
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Electromyographic Characteristics of a Single Motion Shoulder Exercise: A Pilot Study Investigating a Novel Shoulder Exercise by Michael J Henehan, Tamar Brand-Perez, Jeffrey C Peng, Masaaki Tsuruike

“…(p= 0.0109 and 0.0002 respectively) # Conclusion In this pilot study, muscle activation during the single motion, Figure of 8 pattern exercise was not significantly different from the standard shoulder exercises in six of eight key muscles that are usually included in shoulder rehabilitation protocols. …”
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Correction: Pilot study on the effects of assertion video viewing and physical activity on depressive symptoms in workers witnessing workplace bullying by Atsuo Hattori, Yasumasa Otsuka

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Effect of a Yogic Breathing Technique on Immune Parameters among Healthcare Workers: A Randomized Controlled Pilot Study by Archana Balasubramanian, Priyathersini Nagarajan, Mathangi Damal Chandrasekar, Kaviraja Udupa, Emmanuel Bhaskar, Divya Kanchibotla, Saumya Subramanian

“…Thirty-eight subjects were recruited for the pilot study. Among them, 27 were females (71%) and 11 males (29%). …”
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Converting Organic Municipal Solid Waste Into Volatile Fatty Acids and Biogas: Experimental Pilot and Batch Studies With Statistical Analysis by Hojjat Borhany

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A Method for PIO Suppression in Aircraft with Fly-By-Wire Controls: System Development and Validation via Flight Simulator Tests by Rafael Morales Miranda, Jorge Henrique Bidinotto

Subjects: “…Pilot-induced oscillation…”
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The Effect of Vitamin D3 on Serum Creatine Phosphokinase Level in Patients with Multiple Trauma: A Pilot Randomized Clinical Trial by Mehran Kouchek, Niloufar Taherpour, Mahya Farasat, Mirmohammad Miri, Sara Salarian, Seyedpouzhia Shojaei, Rezvan Hassanpour, Hossein Amini, Mohammad Sistanizad

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An Anterior Cruciate Ligament (ACL) Injury Risk Screening and Reduction Program for High School Female Athletes: A Pilot Study by Allison Kuntz, Olivia Peters, Andrew Bello, Ryan Perkins, Ryan Monti, Leigh Murray

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Side Effects and Patient Tolerance with the Use of Blood Flow Restriction Training after ACL Reconstruction in Adolescents: A Pilot Study by Jennifer Prue, Dylan P Roman, Nicholas G Giampetruzzi, Arthur Fredericks, Adel Lolic, Allison Crepeau, J. Lee Pace, Adam P Weaver

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DAILY – A personalized circadian Zeitgeber therapy as an adjunctive treatment for alcohol use disorder patients: results of a pilot trial by Naomi Springer, Naomi Springer, Lisa Echtler, Lisa Echtler, Paul Volkmann, Anisja Hühne-Landgraf, Anisja Hühne-Landgraf, Jasmin Hochenbleicher, Eva Hoch, Eva Hoch, Gabi Koller, Dominic Landgraf

“…Moreover, the general well-being of the IG participants improved more than that of the CG participants.DiscussionThe data from this pilot study show that following a personalized daily structure plan helps AUD patients to remain abstinent during withdrawal therapy. …”
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Comparison of two active warming techniques on body temperature in healthy, anesthetized dogs premedicated with acepromazine or dexmedetomidine: A pilot study. by Jacob P Rastas, Qianqian Zhao, Rebecca A Johnson

“…Glabrous skin on paws may facilitate thermoregulation from this area and is a potential target for interventions attenuating hypothermia. This pilot study aimed to compare efficacy of an innovative warming device placed on the front paws (AVAcore; AVA), with no warming methods (NONE) and conventional truncal warming methods (CONV; circulating water blanket/forced air warmer) on rectal temperature and anesthetic recovery times. …”
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