Effect of glass fiber hybridization and radiation treatment to improve the performance of sustainable natural fiber-based hybrid (jute/glass) composites by S.H. Mahmud, S.C. Das, A. Saha, T. Islam, D. Paul, M.W. Akram, M.S. Jahan, M.Z.I. Molla, M.A. Gafur, R.A. Khan

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Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology by Iryna Omelianenko, Iryna Omelianenko, Nazarii Kobyliak, Nazarii Kobyliak, Tetyana Falalyeyeva, Tetyana Falalyeyeva, Oleksii Seleznov, Pavlina Botsun, Lyudmila Ostapchenko, Oleksandr Korotkyi, Liudmyla Domylivska, Olena Tsyryuk, Galyna Mykhalchyshyn, Tetiana Shapochka, Oksana Sulaieva, Oksana Sulaieva

“…We assume that immune cell density could be an additional diagnostic criterion for differentiating benign and malignant tumors in thyroid aspirates.AimThe current study compared the immune contexture of thyroid adenoma (TA) and thyroid carcinoma (TC) in histological and cytological specimens of III-V categories.Materials and methodsThis pilot study included 72 cases (36 of TA and 36 of TC) with verified histological diagnosis and pre-operative cytology corresponding to categories III, IV and V according to the Bethesda system for reporting thyroid cytology. …”
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Vegetal and Animal Food Proteins Have a Different Impact in the First Postprandial Hour of Impedance-pH Analysis in Patients with Heartburn by Irene Martinucci, Giada Guidi, Edoardo V. Savarino, Marzio Frazzoni, Salvatore Tolone, Leonardo Frazzoni, Lorenzo Fuccio, Lorenzo Bertani, Giorgia Bodini, Linda Ceccarelli, Vincenzo Savarino, Santino Marchi, Nicola de Bortoli

“…Vegetable proteins are associated with a lower number of refluxes, particularly acid refluxes, and with a reduced number of symptoms during the first postprandial hour. This is a pilot study and future investigations are warranted to confirm these results.…”
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Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated by Michele Ammendola, Rosario Sacco, Giuseppe Sammarco, Giuseppe Donato, Valeria Zuccalà, Roberto Romano, Maria Luposella, Rosa Patruno, Carlo Vallicelli, Giorgio Maria Verdecchia, Davide Cavaliere, Severino Montemurro, Girolamo Ranieri

“…The Pearson test correlating MCPT and MVD, c-KitR-EC and MVD was significantly (r=0.64, P=0.001; r=0.66, P=0.041, resp.). Conclusion. In this pilot study, we suggest that MCPT and c-KitR-EC play a role in gastric cancer angiogenesis, so we think that several c-KitR or tryptase inhibitors such as gabexate mesilate and nafamostat mesilate might be evaluated in clinical trials as a new antiangiogenetic approach.…”
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Training for Sustainable and Healthy Building for 2050: New Methodologies for an Integrated and Transnational Education Approach Targeting Skills Development for the Transition Tow... by Maria K. Koukou, Susana Lucas, Julia Justino, Silviano Rafael, Antonios D. Livieratos, Nelson Carriço, John Konstantaras, Michail Gr. Vrachopoulos, Anna Chiara Benedetti, Cecilia Mazzoli, Annarita Ferrante, Mohammad Abdollah Fadel Abdollah, Rossano Scoccia, Jacopo Famiglietti, Tomasz Bakoń, Joanna Aleksiejuk-Gawron

“…In this work, the pedagogical approach used to develop the course contents, curricular development issues, technology, and infrastructure, as well as student support, the results obtained from the evaluation carried out after the pilot training of the eight training courses, and best practices and lessons learned, are presented and discussed. …”
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Using microfluidic shear to assess transfusion requirements in trauma patients by Rachael A Callcut, James T Ross, Anamaria J Robles, Leslie H Vuoncino, Ashli C Barnes, Leonardo W Graeff, Taylor L Anway, Nico T Vincent, Nithya Tippireddy, Kimi M Tanaka, Randi J Mays

“…A decreased maximum PCF showed significant correlation with receiving any transfusion at 6 (p=0.04) and 24 hours (p=0.02) as well as transfusion of pRBCs, fresh frozen plasma, and platelets in the first 6 hours (p=0.03, p=0.03, p=0.03, respectively).Conclusions Assessing coagulopathy in real time remains challenging in trauma patients. In this pilot study, we demonstrated that microfluidic approaches incorporating shear stress could predict transfusion requirements at time of admission as well as requirements in the first 24 hours.Level of evidence Level II.…”
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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Chemotherapy-free option lenvatinib plus anti-programmed cell death protein-1 (PD-1) combination therapy has shown promising results in several malignancies including ovarian cancer, but the toxicity of a high starting dose of lenvatinib is also notable and needs to be improved. Our previous pilot study indicated that a reduced starting dose of lenvatinib may maintain comparable anti-tumor activity with favorable safety in heavily pre-treated ovarian cancer. …”
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Colorado Immersion Training in Community Engagement: Ten years of learning and doing by Leslie A. Wright, Reginaldo Garcia, Mary E. Fisher, Kaylee Gordon, Donald E. Nease, Elizabeth Sweitzer, Crystal LoudHawk-Hedgepeth, Charlene Barrientos Ortiz, Montelle Taméz, Lorenzo Ramírez, Linda Zittleman, Bruno Walther Santos Sobral

“…CIT Alumni secured ∼$8,723,000 in funding between CCTSI Pilot Grants and external funding. Also, CIT alumni implemented CBPR into curricula and community programming and developed deep, lasting relationships. …”
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Increasing Dose of Autologous Bone Marrow Mononuclear Cells Transplantation Is Related to Stroke Outcome: Results from a Pooled Analysis of Two Clinical Trials by Francisco Moniche, Paulo Henrique Rosado-de-Castro, Irene Escudero, Elena Zapata, Francisco Javier de la Torre Laviana, Rosalia Mendez-Otero, Magdalena Carmona, Pilar Piñero, Alejandro Bustamante, Lucía Lebrato, Juan Antonio Cabezas, Alejandro Gonzalez, Grabriel R. de Freitas, Joan Montaner

“…We performed a pooling data analysis of two pilot clinical trials with autologous BM-MNCs transplantation in ischemic stroke patients. …”
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Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…We conducted a retrospective pilot study investigating immunological characteristics of confirmed cases of COVID-19 with or without comorbid T2D. …”
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Measuring the uptake of clinic-based HIV treatment and prevention services following HIV testing and referral at private pharmacies in Kenya by Victor Omollo, Stephanie D. Roche, Shengruo Zhang, Magdalene Asewe, Bernard K. Rono, Benn Kwach, Greshon Rota, Patricia Ong’wen, Kendall Harkey, Josephine Odoyo, Daniel Were, Kenneth Ngure, Elizabeth A. Bukusi, Katrina F. Ortblad

“…To understand what uptake of HIV prevention and treatment services might look like if private pharmacies offered clients free HIV self-testing and referral to clinic-based HIV services, we conducted a pilot study in Kenya. Methods At 20 private pharmacies in Kisumu County, Kenya, pharmacy clients (≥ 18 years) purchasing sexual health-related products (e.g., contraception) were offered free HIV testing. …”
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Associations between muscle quality and whole-body vibration exercise-induced changes in plasma hypoxanthine following an oral glucose load in healthy male subjects by Tomoyuki Hara, Yuya Fujishima, Hitoshi Nishizawa, Yusuke Kawachi, Takashi Nakamura, Seigo Akari, Yoshiyuki Ono, Hirotaka Watanabe, Taka-aki Sakaue, Yoshinari Obata, Hirofumi Nagao, Shiro Fukuda, Takashi Kanamoto, Mitsuyoshi Takahara, Naoto Katakami, Ken Nakata, Iichiro Shimomura

“…Blood levels of hypoxanthine (HX) have been suggested as potential biomarkers associated with intramuscular metabolic dynamics in response to exercise. This pilot randomized crossover trial (UMIN000036520) aimed to investigate the changes in plasma HX after whole-body vibration exercise (WBVE) and their relationships with body composition and muscle-related parameters, enrolling eighteen healthy male volunteers. …”
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Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D by Hugo Fabre, Maxime Ducret, Olivier Degoul, Jonathan Rodriguez, Emeline Perrier-Groult, Elisabeth Aubert-Foucher, Marielle Pasdeloup, Céline Auxenfans, Colin McGuckin, Nico Forraz, Frédéric Mallein-Gerin

“…This chondrogenic differentiation was specifically ascertained by the production of procollagen IIB, the only type II collagen isoform synthesized by well-differentiated chondrocytes. As a pilot study toward cartilage engineering, we encapsulated BM-MSCs in hydrogel and developed an original method to evaluate their chondrogenic conversion by flow cytometry analysis, after release of the cells from the hydrogel. …”
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Transitional analysis for multi-objective operative improvement of reformate quality and hydrogen production from a naphtha catalytic reforming process by F. Velázquez-Alonso, C.A. González-Ramírez, J.R. Villagómez-Ibarra, E.M. Otazo-Sánchez, M. Hernández-Juárez, F. Pérez-Villaseñor, A. Castro-Agüero, L.O. Alemán-Vázquez

“…A numerical multi-objective operative improvement analysis was performed resulting the objective variables as: Research Octane Number (RON) = 90.72, mass fraction of H2 produced (%m of H2) = 2.9, quality of recycled H2 (yH2)R = 0.87, and quality of produced hydrogen (yH2)S = 0.9653. Experimental pilot plant data and full-scale industrial data were compared with simulations observing significant similitudes.…”
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Acute effects of a dog sport on fitness parameters in young adults: a randomised controlled crossover study by Valerio Giustino, Ignazio Leale, Luca Cicero, Luca Petrigna, Monica Lo Nigro, Veronica Fontana, Elena Mignosi, Pietro Cataldo, Antonio Macaluso, Manuel Gómez-López, Giovanni Cassata, Giuseppe Battaglia

“…However, no studies have investigated the impact of dog sports on fitness parameters. This pilot study aimed (a) to evaluate the acute effects of a dog agility course on fitness parameters in young adults and (b) to determine any acute differences after the execution of the dog agility course with and without the dog. …”
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Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review by Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew

“…Two of the studies conducted pilot RCTs assessing the feasibility and acceptability of their interventions, including recruitment, participation, retention, program implementation, adherence, and satisfaction, and 1 study assessed the efficacy of a questionnaire to promote food and vegetable intake. …”
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Improving the Determination of Supernova Cosmological Redshifts by Using Galaxy Groups by Erik R. Peterson, Bastien Carreres, Anthony Carr, Daniel Scolnic, Ava Bailey, Tamara M. Davis, Dillon Brout, Cullan Howlett, David O. Jones, Adam G. Riess, Khaled Said, Georgie Taylor

“…Furthermore, using spectroscopic data from the Anglo-Australian Telescope, we present results from the first pilot program to evaluate whether or not 23 previously unassociated SN Ia hosts belong in groups. …”
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Impact of a 6-Month Micronutrient-Dense Plant-Rich Nutrition Intervention on Health and Well-Being at the Worksite by Jay T. Sutliffe, Julia C. Gardner, Michelle M. Gorman, Mary Jo Carnot, Wendy S. Wetzel, Tricia Fortin, Chloe A. Sutliffe, Alison Adams

“…This nonrandomized pilot study utilized the health belief model and the theory of planned behavior to assess the effectiveness of perceived behavioral control to determine the impact of a micronutrient-dense plant-rich (mNDPR) dietary intervention on employee health and wellness at the worksite. …”
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Protección del Patrimonio en Valparaiso (Chile): Proyecto "MAR VASTO" Heritage protection in Valparaiso (Chile): The "Mar Vasto" project by Maurizio Indirli, Minchel Sotero Apablaza

“…Being the city declared patrimony of the humanity by, UNESCO in 2003, the following main outcomes have been achieved: to evaluate the impact of main hazards (earthquake, tsunami, fire, and landslide); to provide a vulnerability analysis for three historical churches San Francisco, Las Hermanas de la Divina Providencia, La Matriz, comprised of various materials (masonry, concrete, wood, and adobe) and located in different city areas); to carry out an architectural and vulnerability analysis for a pilot building stock in the Cerro Cordillera historic area; to suggest guidelines for future urban planning; and to develop a GIS digital data base (well organized, user-friendly and easy to be implemented in the future), providing hazard maps and scenarios. …”
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Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study by Roberta Bevilacqua, Elvira Maranesi, Marco Benadduci, Gabriella Cortellessa, Alessandro Umbrico, Francesca Fracasso, Giovanni Melone, Arianna Margaritini, Angela La Forgia, Pierpaolo Di Bitonto, Ada Potenza, Laura Fiorini, Carlo La Viola, Filippo Cavallo, Alessandro Leone, Andrea Caroppo, Gabriele Rescio, Mauro Marzorati, Amedeo Cesta, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Lorena Rossi

“…MethodsThe study is designed as a technical feasibility pilot to test the SI-Robotics system. For this study, 20 patients with PD were recruited. …”
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