Cognitive Status Correlates with CXCL10/IP-10 Levels in Parkinson’s Disease by Natália Pessoa Rocha, Paula Luciana Scalzo, Izabela Guimarães Barbosa, Mariana Soares Souza, Isabela Boechat Morato, Érica Leandro Marciano Vieira, Paulo Pereira Christo, Antônio Lúcio Teixeira, Helton José Reis

“…Inflammatory mechanisms have been implicated in PD and its nonmotor symptoms. In the current pilot study, we aimed to evaluate plasma levels of chemokines in PD patients and to analyze the putative association of chemokines with depressive symptoms and cognitive performance. …”
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Linking The Cancer Imaging Archive and GenBank to the National Clinical Cohort Collaborative by Ahmad Baghal, Joel Saltz, Tahsin Kurc, Prateek Prasanna, Samantha Baghal, Janos Hajagos, Erich Bremer, Shaymaa Al‐Shukri, Joshua L. Kennedy, Michael Rutherford, Tracy Nolan, Kirk Smith, Christopher G. Chute, Fred Prior

“…Results The PPRL techniques were piloted using clinical and imaging data sets provided by UAMS. …”
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Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

“…MethodsThe IPOTERI method consists of a telemonitoring platform that guarantees continuity of postoperative care, an intelligent home station based on an Android app for the patient with a user-friendly interface to record vital signals (electrocardiogram, blood pressure, oxygen saturation, and body weight) and access the planning of rehabilitation activities, and a decision support system that communicates with hospital medical records to transmit alerts and specific support information for the formulation and updating of the treatment and care plan. ResultsThe pilot test started in June 2023 (protocol number 20406/2021) including 50 patients who will be monitored for 12-14 weeks using the developed platform, as described in the Procedures subsection of the Methods section. …”
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Stabilization and Solidification of Produced Tailings in the Lead Extraction Process Using Brine Leaching Method by Ravanbakhsh Shirdam, Atefeh Nezami

“…Introduction: Brine leaching tailings (BLT), produced from the pilot scale extraction of lead from zinc filter cakes, contain concentrations of heavy metals that surpass established threshold limits. …”
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Military-Applied Means of Physical Education in Pre-University Educational Institutions of the Russian Ministry of Defence by D. V. Vinograd, A. V. Zykov

“…The quantitative ratio of military-applied methods, which positively influence the system of physical training in the 10th-11th grades, is established. The pilot testing showed that systematic use of special training exercises of military-applied orientation significantly improves the indicators of physical training of students. …”
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On the choice of the method of dynamic rationing of energy resources in oil refineries by V. R. Vedruchenko, E. M. Rezanov, A. P. Starikov, A. V. Kushnarenko, P. A. Surovtsev, V. A. Kikhtenko

“…Thanks to the use of advanced statistical methods, the variability of energy consumption can be interpreted through factor analysis. Through pilot tests, the practical significance of these proposed methods for their practical use in an energy management system is demonstrated, as well as the transition to statistical control of the process.…”
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Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM)... by Seshagiri Rao Nandula, Arad Jain, Sabyasachi Sen

“…Hypothesis We hypothesized that Dapa will improve the outcomes when compared to placebo and the Combo maybe even more beneficial. Methods This is a pilot study evaluating low dose Dapagliflozin 10 mg or low dose Dapa + low dose Saxagliptin combination. 15 subjects were enrolled in 16 weeks, double-blind, three-arm, randomized placebo matched trial, with 10mg Dapa + Saxa placebo (n = 4), 10 mg Dapa + 5 mg Saxa (n = 5) Combo, And Dapa placebo + Saxa placebo (n = 6), Placebo groups. …”
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A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Nurses and midwives are essential to a holistic approach to AMR stewardship (AMS) and IPC within LMICs.Objective(1) Adapt AMS and IPC training programs and practice guidelines for community- and hospital-based nurses and midwives in Nepal; (2) pilot and conduct training outcome and process evaluations.DesignA one-day training was developed through partnerships between Henry Ford Health and nursing and midwifery organizations and teaching facilities in Nepal. …”
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Digital Mindfulness Training for Burnout Reduction in Physicians: Clinician-Driven Approach by Lia Antico, Judson Brewer

“…MethodsTwo separate nonrandomized pilot studies were conducted. In the first study, 27 physicians received the digital MT in a podcast format, while in the second study, 29 physicians and nurse practitioners accessed the same training through a free app-based platform. …”
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Feasibility, acceptability and preliminary effects of a social network-based, peer-led HIV self-testing intervention among men in two Ugandan fishing communities, 2022 by Joseph KB Matovu, Aisha Twahiri Namwama, Linda Kemigisha, Geoffrey Taasi, Jennipher Nakabugo, Julius Wandabwa, Laura M. Bogart, Nuraan Fakier, Rhoda K. Wanyenze, Peter Olupot-Olupot, Joshua Musinguzi, David Serwadda

“…Methods The PEer-led HIVST intervention for MEN (PEST4MEN) is a pilot intervention conducted among men in Kalangala and Buvuma districts. …”
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Assessment of toxic response of Lactuca sativa to compost extracted from agri-food waste by Diego Andr´es Zapata-Gonz´alez, Juan Manuel Trujillo-Gonz´alez, Marco Aurelio Torres-Mora, Daniel Gonz´alez-Santamaria, Raimundo Jim´enez-Ballesta

“…Method: We set up a mini composting pilot where raw materials were classified, chopped into bits, and finally mixed. …”
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The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms by Fenella Beynon, Hélène Langet, Leah F. Bohle, Shally Awasthi, Ousmane Ndiaye, James Machoki M’Imunya, Honorati Masanja, Susan Horton, Maymouna Ba, Silvia Cicconi, Mira Emmanuel-Fabula, Papa Moctar Faye, Tracy R. Glass, Kristina Keitel, Divas Kumar, Gaurav Kumar, Gillian A. Levine, Lena Matata, Grace Mhalu, Andolo Miheso, Deusdedit Mjungu, Francis Njiri, Elisabeth Reus, Michael Ruffo, Fabian Schär, Kovid Sharma, Helen L. Storey, Irene Masanja, Kaspar Wyss, Valérie D’Acremont, TIMCI Collaborator Group

“…In all countries, embedded mixed-method studies further evaluate the effects of the intervention on care and care processes, implementation, cost and cost-effectiveness. Pilot and baseline studies started mid-2021, RCT and post-intervention mid-2022, with anticipated completion mid-2023 and first results late-2023. …”
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Testing a multi-behavioral intervention to improve oral health behaviors in the pediatric dental surgery population: protocol for the PROTECT trial by Joanna Buscemi, Teresa G. Borowski, David Avenetti, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Molly Martin, Molly Martin, Marc S. Atkins, Teresa Marshall, Michael Berbaum, Helen H. Lee, Helen H. Lee

“…We developed PROTECT through an iterative process, incorporating feedback from caregivers, dentists, and community health workers and through a small pilot trial. Caregivers will be recruited at their dental clinic and then will engage in a 10-session intervention with a community health worker. …”
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Protocol for a randomised ‘screen-and-treat’ Helicobacter pylori eradication trial in 14–18-years-old adolescents residing in three regions of Chile: effectiveness and microbiologi... by Ximena Aguilera, Camila Cabrera, Sergio George, Yalda Lucero, Beatriz Zabala Torres, Lilian Fernández, Nora Mamani, Anne Lagomarcino, Miguel O'Ryan

“…Early childhood acquisition of H. pylori with low spontaneous eradication rates underscores the need for preventive measures. Our previous pilot treatment study revealed high eradication rates, favourable tolerance profile and a decline in serum biomarkers indicative of gastric damage in asymptomatic school-aged children. …”
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Adoption of Electric Vehicles and Forecasting Air Emissions in the Metropolitan Area of Mexico City by 2050 by Rodolfo Sosa Echeverría, Graciela Velasco Herrera, Pablo Sánchez Álvarez, Elías Granados Hernández, Gilberto Fuentes García, Victor Manuel Velasco Herrera, Rogelio González Oropeza, William Vicente Rodríguez, Jaime Gandarilla Ibarra, Rodrigo Rivera Rivera

“…Mexico City serves as a pilot laboratory where both the challenges and potential solutions to an issue affecting millions of citizens can be observed. …”
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Topical chlorhexidine 0.2% versus topical natamycin 5% for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial by Victor Hu, David Macleod, Helen Anne Weiss, Matthew J Burton, Simon Arunga, Astrid Leck, Sanjay Kumar Singh, Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, Pankaj Chaudhary, Abhishek Roshan, Einoti Matayan

“…Alternative antifungal medications are needed to treat this blinding disease.Chlorhexidine is an antiseptic agent with antibacterial and antifungal properties. Previous pilot studies suggest that topical chlorhexidine 0.2% compares favourably with topical natamycin. …”
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Translation and Validation of the Italian Version of the Team-Based Learning Student Assessment Instrument (TBL-SAI) in Nursing Students by Valeria Vannini, Rosario Caruso, Sara Alberti, Sergio Rovesti, Paola Ferri

“…The validation process included translation, back-translation, and expert panel review, followed by a pilot test to ensure clarity and comprehension. Data were collected using the self-administered TBL-SAI. …”
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Neurological history both twinned and queried by generative artificial intelligence by Jung-Hyun Lee, Jung-Hyun Lee, Jung-Hyun Lee, Eunhee Choi, Sergio L. Angulo, Sergio L. Angulo, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, Robert A. McDougal, William W. Lytton, William W. Lytton, William W. Lytton

“…A large language model (LLM) could be utilized as a digital twin which could enhance queryable electronic medical record (EMR) systems and provide healthcare conversational agents (HCAs) to replace waiting-room questionnaires.MethodsIn this observational pilot study, we presented verbatim history of present illness (HPI) narratives from published case reports of headache, stroke, and neurodegenerative diseases. …”
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Effects of rotation speed on microstructure and mechanical properties of non-prehole riveting process for high-strength aluminium alloys by Yunpeng Liu, Yunwu Ma, Ming Lou, Entao Zhou, Bowen Zhang, Zhilei Fan, Ende Ge, Huan Zhao, Yongbing Li

“…In this research, an improved friction self-piercing riveting process was developed to connect 2.0 mm + 4.0 mm AA7075-T6 aluminium sheets without pilot holes. To clarify the impact of rivet rotation speed, the axial force, torque, geometric quality, microhardness and mechanical properties were experimentally investigated. …”
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Developing a comprehensive inventory to define harm reduction housing by Sofia Zaragoza, Joseph Silcox, Sabrina Rapisarda, Charlie Summers, Patricia Case, Clara To, Avik Chatterjee, Alexander Y. Walley, Miriam Komaromy, Traci C Green

“…Two expert medical staff unaffiliated with data collection reviewed a draft inventory measuring awareness and utility of HRH inventory components. We then pilot tested the inventory with three HRH residents across two sites for readability and reliability. …”
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