Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreationally ac... by Dawna Salter, Himana Yalamanchi, Aiswarya Yalamanchi, Amulya Yalamanchi

“…It is unknown whether the anti-inflammatory and analgesic properties of B. serrata extend to muscle and joint pain resulting from high-impact eccentric exercise. This pilot study evaluated the efficacy of a standardized B. serrata extract LI51202F1 (SBS) to decrease soreness and improve recovery after repeated bouts of downhill running (DHR) compared to placebo (PLA). …”
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ORGANISING A «SERATA ITALIANA»: A PROJECT-BASED LEARNING EXPERIENCE WITH FLEMISH STUDENTS OF L2 ITALIAN by Elisa De Cristofaro, Irene Cenni, Emma Grootvelt

“…The findings are based on a 5-year pilot experience with Flemish university students enrolled in the Italian Public and Business Communication course at Ghent University (Belgium). …”
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Cohort profile: Noncommunicable diseases and ideal cardiovascular health among people living with and without HIV in Zambia and Zimbabwe (NCDzz cohort) by Gilles Wandeler, Samuel Bosomprah, Cleophas Chimbetete, Belinda Varaidzo Chihota, Guy Muula, Carolyn Bolton-Moore, Tinei Shamu, Ardele Mandiriri, Esau Banda

“…Additionally, we seek to pilot NCD interventions using novel methodologies like the trials within cohorts. …”
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Fecal microbiome change in patients with ulcerative colitis after fecal microbiota transplantation by A. Y. Tikunov, V. V. Morozov, A. N. Shvalov, A. V. Bardasheva, E. V. Shrayner, O. A. Maksimova, I. O. Voloshina, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…Currently, this procedure is recognized as an efficacious method to normalize the intestinal microbiota mainly in inflammatory diseases of the gastrointestinal tract. In Russia, pilot studies of the effectiveness of FT in patients with ulcerative colitis have been conducted for several years, and these studies were started in Novosibirsk. …”
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Head-mounted camera as a debriefing tool for surgical simulation-based training: a randomized controlled study in Senegal by Abdourahmane Ndong, Adja C. Diallo, Armaun D. Rouhi, Diago A. Dia, Sebastian Leon, Cheikhou Dieng, Mohamed L. Diao, Jacques N. Tendeng, Noel N. Williams, Mamadou Cissé, Kristoffel R. Dumon, Ibrahima Konaté

“…Both groups reported increased confidence in performing the task (control group: p = 0.003; camera group: p = 0.0029) and had positive perceptions of the workshop’s effectiveness. Conclusion This pilot study suggests that video feedback with a head-mounted camera is feasible and effective for debriefing during intestinal anastomosis simulation training in a low-resource setting, offering a low-cost, effective way to enhance technical skills. …”
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Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future by Sung-Hsi Huang, Hsun-Yin Huang, Stephane Wen-Wei Ku, Po-Hsien Kuo, Kuan-Yin Lin, Guan-Jhou Chen, Chia-Chi Lee, Yen-Fang Huang, Chien-Ching Hung

“…The sequential introduction of well-tolerated, effective, single-tablet antiretroviral regimens has facilitated the implementation of “treat-all” policy in 2016, rapid ART initiation within 7 days of diagnosis in 2018, and same-day ART initiation in 2021 when immunochromatography was used for rapid confirmation of HIV infection. Government-funded pilot program of pre-exposure prophylaxis for HIV infection, which was launched in 2016 followed by wider enrollment of people at high risk for HIV acquisition in 2018, have contributed to sustained declines of the incidence of HIV infection since 2018, along with high rates of linkage to HIV care, ART initiation, viral suppression, and retention in care in Taiwan. …”
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Efficacy & safety of brolucizumab 6.0 mg versus 3.6 mg in diabetic macular edema by Sanjay Kumar Mishra, Pradeep Kumar, Amrita Joshi, Aman Saraf, Abhijeet Awasthi, Supriya Dhar, Khaleel M, Atul Kumar, Vipin Rana, Ravi D

“…Method A prospective, pilot randomised controlled, single centre, double blinded, two arm comparative study was conducted between Dec 2022 to Apr 2024. …”
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Use of mHealth Technology for Improving Exercise Adherence in Patients With Heart Failure: Systematic Review by Pallav Deka, Erin Salahshurian, Teresa Ng, Susan W Buchholz, Leonie Klompstra, Windy Alonso

“…All studies were mostly feasibility or pilot studies, and the effect of age, sex, race, and NYHA classification on exercise adherence with the use of mHealth was not reported. …”
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Who Are Suitable Patients for Omitting Breast Surgery as an Exceptional Responder in Selected Molecular Subtypes of Breast Cancer After Neoadjuvant Systemic Treatment? by Ebru Sen, Mehmet Ali Nazlı, Göktürk Maralcan, Bekir Sıtkı Said Ulusoy, Mahmut Kaan Demircioğlu, Tuce Söylemez Akkurt, Mehmet Sökücü, Gökmen Umut Erdem, Mustafa Yıldırım

“…<i>Materials and Methods</i>: This two-centre, observational, single-arm, prospective, pilot study was conducted between January and September 2024. …”
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Development and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease by Bohyun Ro, MSc, John P. Spence, BBA, Paul A. Spence, MD, Christian Buckley, BS, Raghu L. Motaganahalli, MD, Bruno T. Roseguini, PhD

“…The prototype's feasibility and safety were evaluated in a single-arm pilot trial with six symptomatic patients with PAD, who were asked to apply the therapy daily for 90 minutes for 12 weeks. …”
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Cross-Platform Ecological Momentary Assessment App (JTrack-EMA+): Development and Usability Study by Mehran Sahandi Far, Jona M Fischer, Svea Senge, Robin Rathmakers, Thomas Meissner, Dominik Schneble, Mamaka Narava, Simon B Eickhoff, Juergen Dukart

“…ResultsWe investigated our platform in a pilot study with 480 days of follow-up to assess participants’ compliance. …”
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Separation of Short-Chain Fatty Acids from Primary Sludge into a Particle-Free Permeate by Coupling Chamber Filter-Press and Cross-Flow Microfiltration: Optimization, Semi-Continuo... by Nikhil Shylaja Prakash, Peter Maurer, Harald Horn, Florencia Saravia, Andrea Hille-Reichel

“…However, high concentrations of solids with SCFAs in hydrolyzed sludge can be highly detrimental to downstream recovery processes. This pilot-scale study addresses this limitation and explores the recovery of SCFAs from primary sludge into a particle-free permeate through a combination of chamber filter-press (material: polyester; mesh size: 100 µm) and cross-flow microfiltration (material: α-Al₂O₃; pore size: 0.2 µm; cross-flow velocity: 3 m∙s⁻¹; pressure = 2.2 bars). …”
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Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy by Danielle Sidsworth, Noah Tregobov, Noah Tregobov, Colin Jamieson, Jennifer Reutens-Hernandez, Joshua Yoon, Geoffrey W. Payne, Geoffrey W. Payne, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers

“…Of note, vascular dysfunction, encompassing both cerebral and peripheral circulation, has been implicated in AD pathogenesis. This pilot study used intravital microscopy to assess differences in responsiveness of gluteal muscle arterioles between a transgenic AD mouse model (APP/PS1; Tg) and wild-type (C57BL/6; WT) mice to further elucidate the role of vascular dysfunction in AD. …”
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Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients by Nevedha Rajan, Toni Kavanagh, Maite LaVega‐Talbott, Sandeep Gangadharan

“…Rapid response EEG (rrEEG) device Ceribell and its Brain Stethoscope function can be used and interpreted rapidly by bedside providers with minimal training. This retrospective pilot study examines the impact of rrEEG introduction at a quaternary care children's hospital on time to definitive diagnosis and treatment, as well as the accuracy of the Brain Stethoscope. …”
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At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…MethodsA 3-arm, single-blinded pilot randomized controlled trial will be conducted to examine the therapeutic effects of at-home immersive VR exergames. …”
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Blinding assessment in randomised sham-controlled trials of acupuncture:protocol for a systematic survey by Ling Li, Xin Sun, Jiali Liu, Minghong Yao, Yong Fu, Jiahui Yang, Xiaochao Luo

“…Paired investigators will independently determine eligibility and use pilot-tested standardised forms for data extraction. …”
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Results from the PROmoting Early Childhood Outside cluster randomized trial evaluating an outdoor play intervention in early childhood education centres by Rachel Ramsden, Dawn Mount, Yingyi Lin, Emily Fox, Susan Herrington, Janet Loebach, Adina Cox, Anita Bundy, Amber Fyfe-Johnson, Ellen Beate Hansen Sandseter, Michelle Stone, Mark S. Tremblay, Mariana Brussoni

“…The PROmoting Early Childhood Outside (PRO-ECO) study is a pilot randomized trial that evaluates the PRO-ECO intervention on children’s outdoor play participation. …”
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Isolation and characterization of CNC from waste maize cob available in Bangladesh as a potential candidate for the fabrication of multifunctional bio-nanocomposites: A new approac... by Shamim Dewan, Md. Mahmudur Rahman, Md. Ismail Hossain, Bijoy Chandra Ghos, M Mohinur Rahman Rabby, Md. Abdul Gafur, Md. Al-Amin, Md. Ashraful Alam

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Barriers and Facilitators to the Preadoption of a Computer-Aided Diagnosis Tool for Cervical Cancer: Qualitative Study on Health Care Providers’ Perspectives in Western Cameroon by Magali Jonnalagedda-Cattin, Alida Manoëla Moukam Datchoua, Virginie Flore Yakam, Bruno Kenfack, Patrick Petignat, Jean-Philippe Thiran, Klaus Schönenberger, Nicole C Schmidt

“…CAD technology can aid diagnostic objectivity; however, data management, workflow adaptation, and infrastructure limitations must be addressed to avoid “pilotitis”—the failure of digital health tools to progress beyond the pilot phase. …”
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Management of sleep apnoea syndrome (SAS) in patients with vasovagal syncope (VVS): a protocol for the VVS-SAS cohort study by Jean Louis Pepin, Nicolas Molinari, Frédéric Gagnadoux, Carey Meredith Suehs, Frédéric Roche, Vincent Puel, Isabelle Godard, Georgios Papaioannou, Philippe Gosse, Fabrice Thoin, Jean Claude Deharo, Naïma Zarqane

“…We therefore designed this pilot study to provide a framework for the observation of changes in outcomes accompanying the deployment of SAS treatments in patients with VVS.Methods and analysis This is a multicentre, registry-based study whose primary objective is to evaluate the effect of SAS management on the number of syncope/presyncope episodes in a population suffering from both VVS and SAS. …”
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