Safety and Tolerance of Donor-Derived Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation: The MYSTEP1 Study by Steffen Hartleif, Michael Schumm, Michaela Döring, Markus Mezger, Peter Lang, Marc H. Dahlke, Joachim Riethmüller, Alfred Königsrainer, Rupert Handgretinger, Silvio Nadalin, Ekkehard Sturm

“…Methods/Design. 7 to 10 children undergoing living-donor pLT will be included in this open-label, prospective pilot trial. A dose of 1 × 106 MSCs/kg body weight will be given at two time points: first by intraportal infusion intraoperatively and second by intravenous infusion on postoperative day 2. …”
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Utilities Associated with the Treatment of Growth Hormone Deficiency (GHD): A Time Trade-off (TTO) Study in the UK and Canada by Kirsch S, Butler G, Jensen LDF, Okkels A, Yssing C, Håkan-Bloch J

“…This study estimates utilities associated with GHD treatment for both people with the disease and caregivers by employing time trade-off (TTO) methodology.Methods: Three online surveys were conducted amongst the general population in the UK and Canada. Based on a pilot, data collection was conducted in two surveys only (Survey A and Survey B). …”
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Paraspinal muscle volume and fatty infiltration after circumferential minimally-invasive deformity correction by John Paul G. Kolcun, Ryan M. Kelly, Bradley L. Kolb, Dustin H. Kim, Alireza Borghei, John E. O'Toole, Richard G. Fessler

“…Preoperative muscle volumes were strongly correlated with postoperative volumes. Conclusions: In this pilot series, paraspinal and psoas muscle volumes were preserved after circumferential MIS deformity correction. …”
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Characterisation of EfbA from the Endodontic Pathogen Enterococcus faecalis and Prediction of Immunodominant EfbA Epitope Peptides: An In-vitro and In-silico Study by Dev Arora, AS Smiline Girija, J Vijayashree Priyadharsini

“…Materials and Methods: An in-vitro and in-silico pilot study was conducted in the Department of Microbiology at Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India. …”
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Methodological and practical aspects of using satellite imagery to assess the military impact on soils by Vitalii Lebed, Maksym Solokha, Vadym Solovei, Anatolii Kucher, Ludmila Vorotyntseva

“…The information derived from satellite imagery serves as a crucial step in developing measures for the restoration of the soil cover in the pilot area affected by military degradation. The study utilised satellite imagery of varying resolutions and geographic information systems to calculate the damage caused by military actions with sufficient accuracy. …”
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Transcranial photobiomodulation for reducing symptoms of autism spectrum disorder and modulating brain electrophysiology in children aged 2–7: an open label study by Yuli Fradkin, Joaquin A. Anguera, Alexander J. Simon, Luis De Taboada, Eugenia Steingold

“…BackgroundSmall pilot studies have indicated that transcranial photobiomodulation (tPBM) may help alleviate symptoms of neurological conditions like depression, traumatic brain injury and Autism Spectrum Disorder (ASD).ObjectiveTo examine the effect of tPBM on the behavioral symptoms of ASD and brain electrophysiology in children aged 2–7.MethodsWe conducted an open label, one-arm study with 23 participants, aged 2–7, previously diagnosed with ASD. …”
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Building on and tailoring to: Adapting a cancer caregiver psychoeducational intervention for rural settings by Erin E. Kent, Kelly R. Tan, Zev M. Nakamura, Jesse Kovacs, Mindy Gellin, Allison Deal, Eliza M. Park, Maija Reblin

“…The enCompass intervention is undergoing ongoing single‐arm pilot of rural cancer patient/caregiver dyads targeting caregiver coping self‐efficacy and patient/caregiver distress (Clinical Trials #NCT05828927).…”
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Application of the flipped classroom model based on Bloom’s Taxonomy of Educational Objectives in endodontics education for undergraduate dental students by Yaru Wei, Zhengjun Peng

“…Results Both learning model cohorts filled out assessment questionnaires upon completion of the pilot curriculum. Compared with the responses from students in the lecture-based group, the self-rating of theoretical knowledge reported by students in the flipped classroom cohort increased by 10.9%, from 7.1 ± 0.8 to 7.9 ± 0.7 (t = 2.912, p < 0.006). …”
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The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution by Eleftheriadi, Klara, Guiglielmoni, Nadège, Salces-Ortiz, Judit, Vargas-Chavez, Carlos, Martínez-Redondo, Gemma I., Gut, Marta, Flot, Jean-François, Schmidt-Rhaesa, Andreas, Fernández, Rosa

“…As part of the European Reference Genome Atlas pilot effort to generate reference genomes for European biodiversity, we present the taxonomic description and chromosome-level genome assembly of a newly described species of Nematomorpha (Gordionus montsenyensis Schmidt-Rhaesa & Fernández sp. nov.). …”
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The scoping, design, and plasma physics optimization of the Eos neutron source stellarator by C.P.S. Swanson, D.A. Gates, S.T.A. Kumar, M.F. Martin, T.G. Kruger, D.W. Dudt, P.J. Bonofiglo, the Thea Energy team

“…On the path to a fusion pilot plant, Thea Energy plans to build Eos, a sub-breakeven, deuterium-deuterium, beam-target fusion, stellarator neutron source facility for producing tritium and other valuable radioisotopes. …”
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Non-governmental organizations’ perceptions of challenges and opportunities for participating in the provision of government-purchased community-based psychiatric rehabilitation se... by Hao Yao, Siyuan He, Fei Yan, Wei Wang, Hanyi Lin, Yanli Liu, Lili Xue, Jun Cai, Weibo Zhang

“…Abstract Background In recent years, the Chinese government has increased its support for the development of community-based psychiatric rehabilitation (CBPR) services and initiated pilot programs for government purchasing of CBPR services from non-governmental organizations (NGOs) in order to address the inadequacy of the government’s own supply capacity of CBPR services. …”
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Strategies to mitigate the impact of the COVID-19 pandemic on child and youth well-being: a scoping review protocol by Jeanna Parsons Leigh, Henry T Stelfox, Perri R Tutelman, Diane L Lorenzetti, Melanie C Anglin, Kirsten M Fiest, Stephana Julia Moss, Emily A FitzGerald, Stacie Smith, Micaela Harley, Kathryn Birnie, Sara J Mizen

“…Findings of this study will be disseminated at national and international conferences and will inform our pan-Canadian multidisciplinary team of researchers, public, health professionals and knowledge users to codesign and pilot test a digital psychoeducational health tool—an interactive, web-based tool to help Canadian youth and their families address poor mental well-being resulting from and persisting beyond the COVID-19 pandemic.…”
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Using a digital health intervention “INTERCEPT” to improve secondary prevention in coronary heart disease (CHD) patients: protocol for a mixed methods non-randomised feasibility st... by Catriona Jennings, Irene Gibson, Marissa Corcoran, John William McEvoy, Lis Neubeck, Lisa Hynes, Faisal Sharif, David Wood, Andrew W Murphy, Molly Byrne

“…Methods This non-randomised, pilot feasibility study with embedded process evaluation will be conducted with a sample of 40 patients in an acute hospital setting. …”
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Review and syntheses: Ocean alkalinity enhancement and carbon dioxide removal through marine enhanced rock weathering using olivine by L. J. J. Geerts, A. Hylén, F. J. R. Meysman, F. J. R. Meysman

“…To more confidently assess the potential and impact of olivine-based mERW, dedicated pilot studies under field conditions are needed, which should be conducted at a sufficiently large spatial scale and monitored for a long enough time with sufficient temporal resolution. …”
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Barriers and facilitators to global access to life-saving skills training: an international cross-sectional survey by Marcus Eng Hock Ong, Freddy Lippert, Lin Zhang, Willem Stassen, So Yeon Joyce Kong, Audrey L Blewer, Yeh Lai Chern, Andrew Fu Wah Ho

“…Data were collected using a custom-designed survey, based on the literature and following pilot testing. Data were analysed descriptively and visualised according to countries and regions. …”
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Using a participatory approach to identify priorities to advance LHS implementation at an academic medical center by Reid M. Eagleson, Madeline Gibson, Carletta Dobbins, Frederick Van Pelt, Allyson Hall, Larry Hearld, Andrea L. Cherrington, Jacob McMahon, Keith Tony Jones, Michael J. Mugavero

“…Initial funding supports a prototype for enhanced health system data access and pilot projects conducted by researchers embedded in health system teams. …”
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Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) by Fekete, Zsófia, Absolon, Dominic E., Michell, Craig, Wood, Jonathan M. D., Goffart, Steffi, Pohjoismäki, Jaakko L. O.

“…Following the previously published brown hare reference genome assembly, the mountain hare is the second Finnish pilot species for the European Reference Genome Atlas (ERGA) initiative, a collaborative effort to generate reference genomes for European biodiversity. …”
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Evaluating a targeted selective speech, language, and communication intervention at scale – Protocol for the Happy Talk cluster randomised controlled trial. [version 3; peer review... by Pauline Frizelle, Darren Dahly, Aoife O'Shea, Aileen Murphy, Cristina McKean

“…Discussion This robust study evaluates a public health approach to the delivery of speech language and communication intervention in the ‘real world’ in the community, which focuses on prevention and equity of access. Pilot work indicates that the programme is feasible, acceptable to parents and staff, cost effective, and suitable for implementation at scale. …”
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Co-designing action-oriented mental health conversations between care providers and ageing Canadians in the community: a participatory mixed-methods study protocol by Carrie McAiney, Paul Holyoke, Heather McNeil, Justine L Giosa, Elizabeth Kalles, Nelly D Oelke, Katie Aubrecht, Olinda Habib Perez

“…Phase 2 includes six co-design workshops with community providers (n=90) in rural and urban sites across three Canadian provinces to co-design tools, resources and processes for enabling the use of the adapted model as a conversation guide. Phase 3 involves pilot and feasibility testing the co-designed conversations with older adult clients of providers from Phase 2 (n=180).Ethics and dissemination Phases 1 and 2 of this study have received ethics clearance at the University of Waterloo (ORE #44187), University of British Columbia (#H22-02306) and St. …”
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Capacitación en obra para obtener la polivalencia de los operarios y verificación de sus efectos en la construcción civil Training on site for the versatility of the workers and ve... by Jorge González Maya Bogado, Paola Valdez Hug, Antonio Edésio Jungles

“…The research was conducted with 22 workers in a pilot site in the city of Encarnación in Paraguay, enabling this to obtain data on changes in production and the impact these have generated in the construction process. …”
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