Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs) by Jeffrey J. Yu, Daniel B. Azzam, Marilyn Chwa, Kevin Schneider, Jang-Hyeon Cho, Chinhui Hsiang, Henry Klassen, M. Cristina Kenney, Jing Yang

“…Mounting evidence suggests that mitochondrial damage and retinal pigment epithelium (RPE) cell death are linked to the pathogenesis of AMD. …”
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Creation of body color mutants by CRISPR/Cas9 gene editing in largemouth bass, Micropterus salmoides by Lina Sun, Tian Gao, Zhiqiang Li, Xiaolong Yang, Zuliang Qin, Mingxiao Ye, Ying Li, Feilong Wang, Deshou Wang

“…In this study, three types of pigment cells, melanophores, iridophores and xanthophores were identified in LMB and melanophores were found first appeared in the iris of eyes in larvae 1.5 days after hatching. …”
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Comparative Assessment of Physical and Chemical Characteristics of Prickly Pear Seed Oil from Opuntia ficus-indica and Opuntia megacantha Varieties by Fatima Ettalibi, Abderraouf El Antari, Allal Hamouda, Chemseddoha Gadhi, Hasnaâ Harrak

“…The evaluated parameters included oil content, free acidity, specific extinction coefficients (K232 and K270), pigment content, fatty acid, and triglyceride composition. …”
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Natural Concurrent Infections with Black Spot Disease and Multiple Bacteriosis in Farmed Nile Tilapia in Central Kenya by Daniel W. Wanja, Paul G. Mbuthia, Robert M. Waruiru, Lilly C. Bebora, Helena A. Ngowi

“…Furthermore, a thick fibrous capsule around the metacercaria, black pigment melanomacrophages, and moderate muscle atrophy were observed. …”
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Development of monoclonal antibodies against P. gingivalis Mfa1 and their protective capacity in an experimental periodontitis model by Mingya Cao, Siyu Wang, Shengke Zhou, Min Yan, Yu Zou, Yuan Cui, Xinyu Lou, Yichang Gao, Ying Chen, Zijing Han, Yi Qian, Jingying Chen, Xia Li

“…ABSTRACT Porphyromonas gingivalis (P. gingivalis), a gram-negative, black-pigmented anaerobe, is a major etiological agent and a leading cause of periodontitis. …”
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Long-Term Effect of Half-Fluence Photodynamic Therapy on Fundus Autofluorescence in Acute Central Serous Chorioretinopathy by Martin Stattin, Stefan Hagen, Daniel Ahmed, Eva Smretschnig, Florian Frommlet, Katharina Krepler, Siamak Ansari-Shahrezaei

“…To evaluate normalized short-wavelength fundus autofluorescence (SW-FAF) imaging changes over time as a predictive parameter for the retinal pigment epithelium (RPE) function in eyes compromised by acute central serous chorioretinopathy (CSCR) after indocyanine green angiography-guided verteporfin (Visudyne®, Novartis Pharma, Basel, Switzerland) photodynamic therapy (PDT) with a half-fluence rate (25 J/cm2). …”
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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…MITF has also been reported to be expressed in non-pigmented cells, such as osteoclasts, mast cells, and B cells. …”
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The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans by Xiangyu Tan, Lin Chen, Ying Chen, Yuxin Li, Lihan Lu, Erfeng Li

“…Compared to the wild type, the growth rate of the mutant ΔFoRab7 strain decreased, the bacteria produced a large amount of pigment deposition, the aerial hyphae decreased significantly, the hyphal branches increased, and the mutant almost lost the ability to produce spores. …”
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Lutein and inflammation: a comprehensive review of its mechanisms of action by Paradentavida Prathyusha, Geetha Viswanathan, Anjilikal Tomy Tomcy, Ponnamparambil P. Binitha, Smitha V. Bava, Edakkadath R. Sindhu

“…It is well-absorbed and systemically localized to the liver, lung, and retina, where it can cross the blood-retina barrier and accumulate in the macular pigment. Due to its anti-oxidative and singlet oxygen quenching properties, lutein is reported to reduce the risk of age-related macular degeneration (AMD). …”
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Preparation of an Intelligent pH Film Based on Biodegradable Polymers for Monitoring the Food Quality and Reducing the Microbial Contaminants by Kumaran Subramanian, Deivasigamani Balaraman, Kumaravel Kaliyaperumal, V. Devi Rajeswari, K. Balakrishnan, P. Ronald Ross, Elumalai Perumal, Pugazhvendan Sampath Renuga, Mani Panangal, Y. Swarnalatha, S. Velmurugan

“…Contact lenses, artificial corneas, wound dressing, suture coating, catheters, and electrode sensors are some of the biomedical applications of hydrogels. The pigment color changes were observed from colorless to pale pink followed by dark reddish-pink. …”
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The Effect of A2E on the Ca2+-PKC Signaling Pathway in Human RPE Cells Exposed to Blue Light by Maomei Luo, Shu Wang, Yun Tang, Chun Zeng, Shanjun Cai

“…In a model of blue light-induced damage in N-retinylidene-N-retinylethanolamine (A2E)-loaded human retinal pigment epithelial (RPE) cells, we examined the effect of A2E on the calcium (Ca2+)-protein kinase C (PKC) signaling pathway. …”
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The Effect of A2E on the Uptake and Release of Calcium in the Lysosomes and Mitochondria of Human RPE Cells Exposed to Blue Light by Mao-Mei Luo, Lin Chen, Shu Wang, Chun Zeng, De-Zhi Li, YeGe Bi, Long-Qian Liu, Shan-Jun Cai

“…We aimed to explore the effect of N-retinylidene-N-retinylethanolamine (A2E) on the uptake and release of calcium in lysosomes and mitochondria by establishing a model of human retinal pigment epithelial (RPE) cell injury induced by exposure to blue light. …”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…In contrast, type 2 closures exhibited sparse cone distribution and a prevalence of large, high-density cells, possibly indicating glial cell proliferation and exposed retinal pigment epithelium (RPE). MH size, rather than duration or preoperative BCVA, was a key determinant of type 1 closure outcomes. …”
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Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism by Kelley C. Larson, Frederick W. Gergits, Abigail J. Renoux, Elizabeth J. Weisman, Borislav Dejanovic, Liyue Huang, Bhaumik Pandya, Donald G. McLaren, Berkley A. Lynch, Richard Fisher, Evan Thackaberry, David Gray, Francois Gaudreault, Christian Mirescu

“…Abstract Microglia dysfunction is implicated in several neurodegenerative disorders, including a rare microgliopathy; CSF1R-related adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (CSF1R-ALSP). CSF1R-ALSP is caused by heterozygous loss-of-function mutations in the colony stimulating factor 1 receptor (CSF1R) gene, which encodes a receptor required for the differentiation of myeloid cells, as well as for microglial survival and proliferation. …”
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Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes by Chloe Wong, Jun Yan Ng, Yang Yie Sio, Fook Tim Chew

“…Various phenotypes such as wrinkling, pigmentation changes, and skin cancers have been linked to specific genetic loci. …”
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Effect of Moisture Stress on Physiological and Yield Responses of Common Bean Varieties at Lath House Condition, Hawassa University, Southern Ethiopia by Mitike Mulatu Alemu, Andargachew Gedebo, Amsalu Gobena Roro, Tatek Tamiru Geletu

“…In the photosynthetic pigment analysis, the highest leaf chl-a, chl-b, and chl-a + b concentration was recorded at 2.4 μg/ml, 1.53 g/ml, and 3.93 μg/ml, respectively, in the Gofta variety irrigated at a four days interval. …”
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Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets by Yuepeng An, Fu Zhao, Hongling Jia, Siyu Meng, Ziwei Zhang, Shuxiao Li, Jiusi Zhao

“…Abstract Melanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. In contrast to non-melanoma skin cancers like basal cell carcinoma and squamous cell carcinoma, melanoma is more invasive. …”
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Halophilic bacteria of salt lakes and saline soils of the Peri-Caspian lowland (Republic of Daghestan) and their biotechnological potential by E. A. Khalilova, S. T. Kotenko, E. A. Islammagomedova, A. A. Abakarova, N. A. Chernyh, D. A. Aliverdiyeva

“…Strain G2 is an extreme halophile capable of growing in the range of 5–25 % NaCl (optimum 25 %) and forming a carotenoid pigment. Mesophil, 30–37 °С (optimum 30 °С); neutrophil, pH 6–8 (optimum 7.2–7.4). …”
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Redox-Modulating Capacity and Effect of Ethyl Acetate Roots and Aerial Parts Extracts from <i>Geum urbanum</i> L. on the Phenotype Inhibition of the <i>Pseudomonas aeruginosa</i> L... by Lyudmila Dimitrova, Milka Mileva, Almira Georgieva, Elina Tzvetanova, Milena Popova, Vassya Bankova, Hristo Najdenski

“…This study aimed to investigate the redox-modulating capacity and effect of ethyl acetate (EtOAc) extracts from roots (EtOAcR) and aerial parts (EtOAcAP) of the Bulgarian plant on the phenotype inhibition of the <i>P. aeruginosa</i> Las/RhI quorum sensing (QS) system, which primarily determines drug resistance in pathogenic bacteria, including biofilm formation, motility, and pigment production. We performed QS assays to account for the effects of the two EtOAc extracts. …”
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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…After PDA-JAKi MN treatment, the symptoms of vitiligo in mice are alleviated, and the affected areas regain pigmentation. Enhancements have been observed in the dermal thickness, the numbers of melanocytes and the content of melanin within the treated skin area. …”
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