The compensatory enrichment of sphingosine-1-phosphate on HDL in FSGS enhances the protective function of glomerular endothelial cells compared to MCD by Yunfeng Xiong, Qiuping Ye, Lifang Liu, Wanjun Lin, Yonggen Liao, Ruiyu Gao, Jiaming Xu, Xinyu Zhang, Ruoyan Chen, Sihui Chen, Qiaoling Chen, Lixin Wei

“…The mechanism underlying the regulation of p-eNOS expression by rHDL was associated with the PI3K-AKT signaling pathway. The enhanced presence of S1P on HDL could serve as a diagnostic marker to differentiate FSGS from MCD. …”
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Intervertebral Disc Degeneration in Long-Term Postoperative Patients with Adolescent Idiopathic Scoliosis: MRI Evaluation 34-51 Years after Surgery and its Changes during Middle an... by Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Yasushi Iijima, Yoshiaki Torii, Jun Ueno, Atsuhiro Yoshida, Ken Tomochika, Sumihisa Orita, Yawara Eguchi, Kazuhide Inage, Yasuhiro Shiga, Junichi Nakamura, Yusuke Matsuura, Takane Suzuki, Hisateru Niki, Seiji Ohtori, Shohei Minami

“…Sagittal alignment parameters, such as sagittal vertical axis (SVA), pelvic incidence minus lumbar lordosis (PI-LL), and pelvic tilt (PT), worsened over time. …”
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Mechanism of salvianolic phenolic acids and hawthorn triterpenic acids combination in intervening atherosclerosis: network pharmacology, molecular docking, and experimental validat... by Qu Zhai, Shixi Shang, Zihan Zhang, Lihua Sun, Ying Huang, Shuyi Feng, Qian Wu, Haifeng Cui, Xiaolu Shi

“…Additionally, the expression of PI3K, Akt, NF-κB, JNK1, ERK1/2, and p38-MAPK in the aortic arteries was analyzed. …”
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Efficacy of Andrographis paniculata, Psidium guajava and Piper betle as Prevention on Motile Aeromonad Septicaemia Infection in African Catfish (Clarias sp.) by D. Wahjuningrum, . Tarono, S.L. Angka

“…The dosage of herbal medicine per 100 gram of diet was PI (1.0 g sambiloto, 0.75 g daun jambu and 0.25 g daun sirih), PII (1.0 g sambiloto,  0.50 g daun jambu,  0.50 g daun sirih), and PIII (1.0 g sambiloto, 0.25 g daun jambu, and 0.75 g daun sirih).  …”
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Development and optimization of a new competitive ELISA using recombinant (rPSA D15 and rCag11) antigens for the detection of Helicobacter pylori infection. by Biniam Moges Eskeziyaw, Naomi Maina, Rebecca Waihenya, Matthew Mutinda Munyao, Tonny Teya Nyandwaro, Shingo Inoue, Samson Muuo Nzou

“…Based on the optimized conditions, novel rPSA D15-cELISA and rCag11-cELISA assays with a respective optimum cut-off value of 20.80% PI and 24.16% PI were developed. According to the receiver operating characteristic (ROC) curve analysis on the diagnostic performance of the newly developed rPSA D15-cELISA and rCag11-cELISA assays using 60 clinical H. pylori stool samples, the rPSA D15-cELISA test assay established an optimum cut-off point of 20.80% with sensitivity and specificity of 90% (95% confidence of interval (CI) 74.38-96.54), Area under the curve (AUC) of 0.9556 (95% CI = 0.896-1.000) and P value <0.0001. …”
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Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms by Dustin Anderson, Grayson Beecher, Fang Ba

“…Parkinson’s disease (PD) is a progressive neurodegenerative condition characterized by bradykinesia, tremor, rigidity, and postural instability (PI), in addition to numerous nonmotor manifestations. …”
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Intelligent Control of a Photovoltaic Generator for Charging and Discharging Battery Using Adaptive Neuro-Fuzzy Inference System by El Hadji Mbaye Ndiaye, Alphousseyni Ndiaye, Mactar Faye, Samba Gueye

“…A regulation of the DC bus voltage is also carried out by means of a PI corrector for a good supply of the load. The simulation results under MATLAB/Simulink show that the method proposed in this work allows the PV system to function normally by charging and discharging the battery whatever the weather conditions.…”
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Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells by Yao Liu, Mei Wei, Xiang Mao, Taisheng Chen, Peng Lin, Wei Wang

“…The role of the mitogen-activated protein kinase (MAPK), phosphoinositide-3 kinase/protein kinase B (PI3K/Akt), Notch/Wnt/Atoh1, calcium channels, and oxidative stress/reactive oxygen species (ROS) signaling pathways are the most relevant. …”
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Stone axe heads hoard from Sant’Alessandro, Volterra (Pisa): a case of ceraunia deposit? by Andrea Pessina, Elena Sorge, Fabrizio Burchianti, Federico Bernardini, Francesco Princivalle, Andrea Fragiacomo

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Os discursos protetivos e punitivos acerca dos adolescentes em medida de internação no Brasil by Denise Maria Leal, João Paulo Macedo

“…El presente artículo tiene como objetivo aprehender los sentidos de protección integral en la atención al adolescente que cumple la medida de internación en el Centro Educativo Masculino (CEM) en Teresina-PI, Brasil. Esta investigación fue desarrollada a través de una entrevista semiestructurada con ocho trabajadores y el análisis documental del Plan Individual de Atención (PIA), del Informe Técnico Evaluativo (ITE), de las fichas de evolución del caso, de la sentencia, del informe de evaluación sobre in locus y de la medida socioeducativa pública. …”
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Polydatin Protects Bone Marrow Stem Cells against Oxidative Injury: Involvement of Nrf 2/ARE Pathways by Meihui Chen, Yu Hou, Dingkun Lin

“…Hochest 33258, Annexin V-PI, and Western blot assay showed H2O2-induced apoptosis in BMSCs, which was attenuated by polydatin. …”
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Anterior chamber parameters after laser iridotomy in primary angle-closure spectrum by B. S. Chetana, Y. M. Manjula

“…Objectives: To study central anterior chamber depth morphology (CACD) anterior chamber volume (ACV), anterior chamber angle (ACA) in primary angle closure disease patients using rotating scheimpflug camera (pentacam) before and after laser PI. Methods: 91 eyes of 50 patients having PACD changes in CACD, ACV, ACA were evaluated using rotating scheimpflug camera before and after laser peripheral iridotomy. …”
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Transoesophageal Echocardiography for Monitoring Liver Surgery: Data from a Pilot Study by Filipe Pissarra, Antonio Oliveira, Paulo Marcelino

“…The comparison between 39 CO paired measurements obtained by TEE and PiCCO2 revealed a statistically significant correlation (P<0.001, r=0.83). …”
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Advancements in Research on Non-AR- Signaling Pathways and Targeted Therapies for Castration-Resistant Prostate Cancer by Haq Dad, Asger Hansen

“…Prominent pathways in the disease include PI3K-Akt-mTOR, Wnt, Hippo, Hedgehog, Notch, HOXB13, and Jak2-Stat5a/b. …”
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Axion dark matter, proton decay and unification by Pavel Fileviez Pérez, Clara Murgui, Alexis D. Plascencia

“…In this context, we predict an upper bound for the proton decay channels with antineutrinos, τ p → K + ν ¯ ≲ 4 × 10 37 $$ \tau \left(p\to {K}^{+}\overline{\nu}\right)\lesssim 4\times {10}^{37} $$ yr and τ p → π + ν ¯ ≲ 2 × 10 36 $$ \tau \left(p\to {\pi}^{+}\overline{\nu}\right)\lesssim 2\times {10}^{36} $$ yr. …”
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Controlling Transformer Magnetizing Offset Current in Isolated Phase-Shift Full-Bridge Converters Using a Luenberger Observer by Angelika Neumann, Sönke Meynen, Ahmad Rahmoun, Daniel Ziegler, Thomas Kirchartz

“…The observer model, in combination with a PI-controller, directly interventions the duty cycle and removes any DC-offset current resulting from both issues. …”
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Heat Transfer and Friction in a Low-Aspect-Ratio Rectangular Channel with Staggered Slit-Ribbed Walls by Jenn-Jiang Hwang, Tong-Miin Liou

“…Effects of rib open-area ratio (β= 24%, 37%, and 46%), rib pitch-to-height ratio (Pi/H=10,15and20), and Reynolds number (10,000≤Re≤50,000) are examined. …”
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Application of ZnO Semiconductor Nanomaterial Ink in Packaging and Printing Design by Changjian Guo

“…After inkjet printing on the PI flexible substrate, after curing at 300°C for 30 min, the pattern surface is smooth and clear, and the outline is clear. …”
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Robust Control of Aeronautical Electrical Generators for Energy Management Applications by Giacomo Canciello, Alberto Cavallo, Beniamino Guida

“…Electric generators used for aeronautical application involve several machines, including a main generator and an exciter. Standard regulators (PI or PID-like) are normally used for the rectification of the generator voltage to be used to supply a high-voltage DC bus. …”
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Student’s Learning Profile as a Tool of Personal Learning Logistics by M. E. Kushnir, P. D. Rabinovich, K. E. Zavedenskiy, I. S. Tsarkov

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