Worker Protection Standard (WPS) Responsibilities and Compliance by Emily Kraus, Brett Bultemeier

“…Written by Emily Kraus and Brett Bultemeier. https://edis.ifas.ufl.edu/pi294 …”
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G蛋白 βγ亚基介导的信号转导途径与心肌细胞肥大 by 郑　猛综述, 余细勇审校

“…异三聚体G 蛋白由 α、β 和γ亚基所组成,最近发现 Gβγ可以激活 PI3Kγ、Ras、MAPKs 等,参与引起心肌细胞肥大反应的细胞内信号转导通路,可作为防治心肌肥厚的新靶点。…”
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Microsoft Teams for CEU and Training Delivery by Brett W. Bultemeier, Joe Gasper

“…Bultemeier and Joe Gasper and published by the UF/IFAS Pesticide Information Office. https://edis.ifas.ufl.edu/pi290 …”
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The EPA Conventional Reduced Risk Pesticide Program by Frederick M. Fishel

“…http://edis.ifas.ufl.edu/pi224 …”
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A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers by Ersen Kameri, Ersen Kameri, Ersen Kameri, Vera Helena Jepsen, Pawel Stachura, Pawel Stachura, Nadine Rüchel, Rigveda Bhave, Leticia Benitez, Fatima Crispi, Eduard Gratacos, Nico Dragano, Stefan Janssen, Arndt Borkhardt, Arndt Borkhardt, Aleksandra Pandyra, Aleksandra Pandyra, Aleksandra Pandyra, Gesine Kögler, Gesine Kögler, Ute Fischer, Ute Fischer, Ute Fischer

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Diverse real-life outcomes after intensive risk-adapted therapy for 1034 AML patients from the CETLAM Group by Guadalupe Oñate, Ana Garrido, Montserrat Arnan, Helena Pomares, Ester Alonso, Mar Tormo, Marina Diaz-Beya, Susana Vives, Lurdes Zamora, Antonia Sampol, Rosa Coll, Olga Salamero, Marta Cervera, Antoni Garcia, Ferran Vall-Llovera, Sara Garcia-Avila, Joan Bargay, Xavier Ortin, Eva Iranzo, Francisca Guijarro, Marta Pratcorona, Josep F. Nomdedeu, Jordi Esteve, Jorge Sierra

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Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis by Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, Benjamin Lefevre, Muhammad Farooq, Aurélien Jan, Christelle Manuel, Laurence Touami-Bernard, Catherine Lucas-Clerc, Valentine Genet, Hugues Gascan, Jean-Philippe Girard, Frédéric Chalmel, Lucie Lamontagne, Claire Piquet-Pellorce, Michel Samson

“…An increased depletion of B and T lymphocytes, NKT cells, dendritic cells, and macrophages was observed 48 h postinfection (PI) in IL-33 KO mice than that in WT mice. In contrast, a massive influx of neutrophils was observed in IL-33 KO mice at 48 h PI. …”
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fMLP-Induced IL-8 Release Is Dependent on NADPH Oxidase in Human Neutrophils by María A. Hidalgo, María D. Carretta, Stefanie E. Teuber, Cristian Zárate, Leonardo Cárcamo, Ilona I. Concha, Rafael A. Burgos

“…Because the role of ROS on IL-8 release in neutrophils is until now controversial, we assessed if NADPH oxidase is involved in the IL-8 secretions and PI3K/Akt, MAPK, and NF-κB pathways activity induced by fMLP. …”
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Automated Audit and Self-Correction Algorithm for Seg-Hallucination Using MeshCNN-Based On-Demand Generative AI by Sihwan Kim, Changmin Park, Gwanghyeon Jeon, Seohee Kim, Jong Hyo Kim

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Poldip2/Nox4 Mediates Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Lung Epithelial Cells by Yueguo Wang, Zhenxing Ding, Youhui Tu, Xu Wu, Wenying Zhang, Shuang Ji, Jilong Shen, Li Zhang, Huimei Wu, Guanghe Fei

“…Furthermore, inhibiting of PI3K-AKT signaling notably attenuated LPS-induced Poldip2/Nox4 activation. …”
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Prognostic Value of PSMB5 and Correlations with LC3II and Reactive Oxygen Species Levels in the Bone Marrow Mononuclear Cells of Bortezomib-Resistant Multiple Myeloma Patients by Eva Plakoula, Georgios Kalampounias, Spyridon Alexis, Evgenia Verigou, Alexandra Kourakli, Kalliopi Zafeiropoulou, Argiris Symeonidis

“…The elevated oxidative stress in PI-treated patients could possibly serve as an additional compensatory mechanism.…”
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Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13 by Cheng Tan, Hang Zhou, Qiangfei Xiong, Xian Xian, Qiyuan Liu, Zexin Zhang, Jingjing Xu, Hao Yao

“…Cromolyn sodium intervention and mast cell knockout alleviate the symptoms of pulmonary fibrosis probably via the PI3K/AKT/mTOR signaling pathway. Therefore, mast cell inhibition is a potential therapeutic target for sepsis-induced pulmonary fibrosis.…”
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慢病毒介导shRNA抑制垂体腺瘤PTTG基因表达及对细胞增殖和侵袭能力的影响

“…【结果】 细胞转染表达PTTG基因shRNA的慢病毒载体后,能显著抑制肿瘤细胞PTTGmRNA和蛋白的表达,与对照组相比有统计学差异(P < 0.05),细胞的增殖能力受到明显抑制,且增殖抑制效应具有时间依赖性;细胞生长显著变慢,G0/G1期细胞比例显著增高,克隆形成能力下降,细胞侵袭能力也显著减弱,均与对照组相比有统计学差异(P < 0.05)?PI3K等信号通路的基因表达也发生显著变化?【结论】 慢病毒介导shRNA沉默PTTG基因表达可能是通过对PI3K信号通路的调控,抑制了GH3和AtT20垂体腺瘤细胞的生长,抑制肿瘤细胞的体外增殖和侵袭能力?…”
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Risk prediction tools for pressure injury occurrence: an umbrella review of systematic reviews reporting model development and validation methods by Bethany Hillier, Katie Scandrett, April Coombe, Tina Hernandez-Boussard, Ewout Steyerberg, Yemisi Takwoingi, Vladica Velickovic, Jacqueline Dinnes

“…Our objectives were to identify and describe available risk prediction tools for PI occurrence, their content and the development and validation methods used. …”
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Could the arm blood pressure measured with simultaneous bilateral arm method be used for hypertension diagnosis? by Taixuan Wan, Yuanhao Wu, Ziqiang He, Hai Su

“…The percentage increase (PI) was calculated on the formula: (RA-2−RA-1)/RA-1.Results The RA-2 on systolic blood pressure (SBP)/diastolic blood pressure (DBP) was slightly, but statistically higher by 1.2/0.4 mm Hg against the RA-1. …”
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Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention by Rodrigo Fonseca, Yuan Xiao Zhu, Laura A. Bruins, Joseph Ahmann, Cecilia de Bonolo Campos, Esteban Braggio, Xianfeng Chen, Mariano Arribas, Susie Darvish, Seth Welsh, Erin Meermeier, Kiran K. Mangalaparthi, Richard K. Kandasamy, Greg Ahmann, J. Erin Wiedmeier-Nutor, Akhilesh Pandey, Marta Chesi, P. Leif Bergsagel, Rafael Fonseca

“…Upstream signaling pathways, including growth factor receptor tyrosine kinase (RTK) and phosphoinositide-3-kinase (PI3K) were implicated in this dysregulation. Simultaneous inhibition of MCL-1, BCL-XL, and upstream PI3K, RTK (FGF, EGF, and IGF1) mediated signaling enhanced VTX sensitivity. …”
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Prediction of time-dependent bearing capacity of concrete pile in cohesive soil using optimized relevance vector machine and long short-term memory models by Jitendra Khatti, Mohammadreza Khanmohammadi, Yewuhalashet Fissha

“…The performance index (PI), the variance accounted for (VAF), performance (R), mean absolute error (MAE), normalized mean bias error (NMBE), and root mean square error (RMSE) matrices have analyzed the prediction capabilities of each model. …”
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Triiodothyronine (T3) increases the expression of the amphiregulin (AREG) oncogene by activating extranuclear pathways in MCF-7 breast cancer cells by Maria Teresa De Sibio, Fernanda Cristina Fontes Moretto, Regiane Marques Castro Olimpio, Miriane de Oliveira, Lucas Solla Mathias, Vinícius Vigliazzi Peghinelli, Helena Paim Tilli, Bianca Mariani Gonçalves, Dariane Beatriz Marino Cardoso, Larissa Silva Dall Aqua, Igor de Carvalho Depra, Mariana Menezes Lourenço, Aline Carbonera Luvizon, Paula de Oliveira Montandon Hokama, Maria Tereza Nunes, Marna Eliana Sakalem, Célia Regina Nogueira

“…Materials and methods: We treated MCF-7 cells with T3 (10 nM) for 1 hour in the presence or absence of inhibitors for αvβ3 integrin (RGD peptide), MAPK (PD98059), PI3K (LY294002), and protein synthesis (cycloheximide [CHX]). …”
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Effect of PCSK9 inhibitor on early neurological deterioration in acute ischemic stroke patients with a history of coronary heart disease: a study protocol for a randomized controll... by Xing Gong, Xinting Yu, Lanlan Pu, Yang Jiao, Lin Liu, Hua Cao, Xiaofei Ji

“…The PI group will receive a combination therapy consisting of evolocumab and rosuvastatin calcium tablets, while the AT group will receive only oral rosuvastatin calcium tablets. …”
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Coculture with Eastern oysters is unlikely to reduce OsHV-1 impacts to farmed Pacific oysters: A modelling approach by Familusi Oluwatosin Adekunle, Gorka Bidegain, Tal Ben-Horin

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