-
1481
Prediction of hemolytic peptides and their hemolytic concentration
Published 2025-02-01“…These models outperform existing methods and are implemented in HemoPI2, a web-based platform and standalone software for designing peptides with desired HC50 values ( http://webs.iiitd.edu.in/raghava/hemopi2/ ).…”
Get full text
Article -
1482
Latent Inflammation and Insulin Resistance in Adipose Tissue
Published 2017-01-01“…We further hypothesize that insulin-activated PI3-kinase pathway and inflammatory signaling mediated by several IκB kinases may constitute negative feedback leading to insulin resistance at least in the fat tissue. …”
Get full text
Article -
1483
Scaling Analysis on Pulsating Flame Spread over Liquids
Published 2008-01-01“…These three influences form two independent pi-numbers: the Marangoni (Ma) number and Grashof (Gr) number, which include the characteristic length scale ratio (depth of subsurface circulation)/(horizontal length of preheated liquid surface). …”
Get full text
Article -
1484
Microbially produced imidazole propionate impairs prostate cancer progression through PDZK1
Published 2025-01-01“…Mechanistic studies indicate that IMP exerts its effects by upregulating PDZK1 expression, which subsequently inhibits the phosphorylation of the PI3K-AKT pathway. Conclusions In conclusion, IMP significantly inhibits the progression of PCa, offering new insights into potential treatments for CRPC.…”
Get full text
Article -
1485
Construct validity test on the Indonesian version of Career Decision-Making Self-Efficacy Scale (CDSES)
Published 2023-03-01“…A construct validation analysis was carried out, incorporating the NEO-PI instruments developed by Costa & McCrae in 1992 into CDSES-Indonesia version. …”
Get full text
Article -
1486
Multivariate Cox regression analysis of prognostic genes and therapeutic mechanisms of gastric cancer
Published 2025-02-01“…Functional enrichment analysis showed that KG was mainly involved in cell adhesion molecules, adhesion spots and PI3K/AKT signaling pathway. KG may be a potential therapeutic target for gastric cancer.…”
Get full text
Article -
1487
Multi-Scale Robotics: A Numerical Investigation on Mobile Micro-Tweezers for Micro-Manipulation with Extreme Requirements
Published 2024-12-01“…The said magnetic field is articulated by an open-kinematic chain controlled with a simple adaptive PI-control scheme. A vortex is formed as the spherical particle, assumed to be submerged under the surface of fluid, and follows the position and orientation of the external magnetic field. …”
Get full text
Article -
1488
Trifolirhizin: A Phytochemical with Multiple Pharmacological Properties
Published 2025-01-01“…Mechanistic studies of trifolirhizin showed that it could act on important target genes and pathways such as the NF-κB-MAPK, EGFR-MAPK, AMPK/mTOR, and PI3K/Akt signaling pathways. These pathways are also implicated in various other diseases, suggesting the potential of trifolirhizin in therapeutic applications. …”
Get full text
Article -
1489
Advanced Facial Recognition Systems for Real-Time Embedded Applications
Published 2025-01-01“…Leveraging the Intel RealSense 415 camera connected to a Raspberry Pi 3. An introduction to Haar Cascading models is provided, highlighting their advantages, particularly their ability to ensure acceptable levels of accuracy for facial recognition in unseen image collections. …”
Get full text
Article -
1490
Leave or stay? A narrative inquiry of tensions in novice English teachers’ professional identity construction at China’s private universities
Published 2025-02-01“…Participants reconciled three selves and adopted two approaches (assimilation and dissimilation) to navigate PI tensions. Policy makers are suggested to offer a well-established identity policy and sufficient research funding to facilitate the academic development of both private universities and teachers there. …”
Get full text
Article -
1491
First-Order and High-Order Repetitive Control for Single-Phase Grid-Connected Inverter
Published 2020-01-01“…The main idea of this paper is to develop a composite control including a PI control and repetitive control for a single-phase grid-connected inverter to eliminate the effects of harmonics, which can obtain better steady-state and dynamic responses of the single-phase inverter system and reduce the net current harmonics. …”
Get full text
Article -
1492
Transmembrane Amino Acid Transporters in Shaping the Metabolic Profile of Breast Cancer Cell Lines: The Focus on Molecular Biological Subtype
Published 2024-12-01“…In addition to the main signaling pathway PI3K/Akt/mTOR, the activity of the oncogene c-Myc, HIF, p53, GATA2, NF-kB and MAT2A have a direct effect on the amino acid metabolism of cancer cells, their growth and proliferation, as well as the maintenance of homeostatic equilibrium. …”
Get full text
Article -
1493
Russian-Greek Political and Ecclesiastical Relations in 20-30s of the 19th Century
Published 2020-07-01“…The first ambassador was P.I. Rickman, who arrived with aim to provide political relations with this new Balkan state. …”
Get full text
Article -
1494
Comparison Between Connection Based Modified Indices and Coindices for Product of Networks
Published 2022-01-01“…In 1972, connection number based TIs are studied by Gutman and Trinajstić to calculate the entire <inline-formula> <tex-math notation="LaTeX">$\pi $ </tex-math></inline-formula>-electron energy of the alternant hydrocarbons. …”
Get full text
Article -
1495
Specialized contact sites regulate the fusion of chlamydial inclusion membranes
Published 2024-10-01“…Fusion depends on IncA clustering within ICSs and is regulated by PI(3,4)P2 and sphingolipids. As IncA concentrates within ICSs, its C-terminus likely interacts in trans with IncA on the apposing membrane, securing a high concentration of IncA at fusion sites. …”
Get full text
Article -
1496
Photovoltaic High-Frequency Pulse Charger for Lead-Acid Battery under Maximum Power Point Tracking
Published 2013-01-01“…A duty control, guided by a power-increment-aided incremental-conductance MPPT (PI-INC MPPT), is implemented to the BCC that operates at maximum power point (MPP) against the random insolation. …”
Get full text
Article -
1497
Numerical characterization of the performance of counter-flow double-pipe heat exchanger using nanofluids for laminar flow regime
Published 2025-03-01“…In comparison to other nanofluids, lower density nanofluids, such Ash/H2O, had larger pressure drop and pumping power. The Buckingham Pi theorem was used to perform nondimensionalization analysis. …”
Get full text
Article -
1498
Discovery of potent allosteric antibodies inhibiting EGFR
Published 2024-12-01“…In particular, we identified one clone that is more potent than the approved blocking antibody cetuximab in inhibiting both PI3K/AKT and MAPK/ERK pathways. Our results suggest that allosteric antibodies may be potential new modalities for therapeutics.…”
Get full text
Article -
1499
Biomechanical Performances of Networked Polyethylene Glycol Diacrylate: Effect of Photoinitiator Concentration, Temperature, and Incubation Time
Published 2016-01-01“…This study also found statistically significant effect of network architecture, PI concentration, temperature, and wait time on the maximum failure stress of PEGDA samples (P value < 0.05). …”
Get full text
Article -
1500
Association of PIK3CA somatic mutations with clinicopathological parameters in breast cancer
Published 2024-12-01“…The enzyme phosphatidylinositide-3-kinase (PI3K) regulates cellular proliferation and apoptosis. …”
Get full text
Article