Regulating the PI3K and AMPK pathway: the secret of 1-deoxynojirimycin's success in alleviating chronic diseases by Chengwei Yu, Qirui Hu

“…Therefore, here we summarized the understanding of the molecular mechanisms underlying the effects of DNJ on the chronic diseases, proposed the key molecular mediators (phosphatidylinositol 3-kinase (PI3K) and adenosine 5′-monophosphate-activated protein kinase (AMPK)) and discussed the future directions to promote the application of DNJ.…”
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The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway by Nana Wang, Tiegang Li, Ping Han

“…Furthermore, we also observed that TMXKP could significantly decrease IRS-1, IRS-2, PI3-K p85α, and AKT2 gene expression and also IRS-1, IRS-2, PI3-K, AKT2, and p-AKT2 protein expression levels P<0.05 in diabetic rats. …”
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Corrigendum to: TIPE1 suppresses the invasion and <?A3B2 pi6?>migration of breast cancer cells and inhibits <?... by Qiu Shusheng, Hu Wei, Ma Qiuhong, Zhao Yi, Li Liang, Ding Yu

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Design of PI Controller for Voltage Controller of Four-Phase Interleaved Boost Converter Using Particle Swarm Optimization by Ittipon Laoprom, Satean Tunyasrirut

“…This article introduces voltage feedback controlling using the PI controller tuned gains by metaheuristic optimizations for a four-phase interleaved boost converter. …”
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CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…Positive correlations for SYTO9/PI staining were noted in other species (r = 0.65 - 0.79). …”
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NT5E Mediates Cisplatin Resistance in NSCLC Through the PI3K-AKT Signaling Pathway by Liangfeng Zheng, Jian Liu, Feiyue Ji, Chunxiang Li, Ye Qian, Lili Shao, Xiaomin Lu

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Enhanced Sensor Placement Optimization and Defect Detection in Structural Health Monitoring Using Hybrid PI-DEIM Approach by Minyoung Yun, Mikhael Tannous, Chady Ghnatios, Eivind Fonn, Trond Kvamsdal, Francisco Chinesta

“…The proposed algorithm has successfully located defects with low error, especially when using hybrid sensors, which combine the most critical sensors identified through both PI and DEIM. This hybrid method identifies defects with the lowest errors compared to using either the PI or DEIM methods alone.…”
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Design of PMSM Dual-Loop Control Systems Integrating LADRC and PI Controllers via an Improved PSO Algorithm by Baoye Song, Ruoyu Wang, Lin Xu

“…The use of an internal model control scheme to initialize the parameters of the proportional-integral- (PI-) based current controller simplifies the search space of the control system parameter optimization. …”
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Effect of Electroacupuncture on Chondrocyte Apoptosis in Knee Osteoarthritis Rat Based on PI3K/Akt Signaling Pathway by Yuanyuan ZHANG, Xinyu JIANG, Xihai LI, Mingxia WU

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Stratospheric X‐Rays Detected at Midlatitudes With a Miniaturized Balloon‐Borne Microscintillator‐PiN Diode System by K. L. Aplin, G. J. Marlton, V. Race

“…Abstract A miniaturized scintillator (“microscintillator”), was flown on a meteorological radiosonde to observe energetic particles in the lower atmosphere. A PiN diode was used to measure the light from the microscintillator to count rates and energies of ionizing radiation from the ground up to the stratosphere (32 km). …”
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Comparative analysis of PI and fuzzy logic controller for grid connected wind turbine under normal and fault conditions by Mohamed Bahgat, Mohamed Ezzat, Mahmoud A. Attia, S. F. Mekhamer, Nourhan M. Elbehairy

“…Additionally, the FLC outperforms the enhanced PI in fault conditions by reducing peak-to-peak oscillations by about 30–65%. …”
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Interleaved Landsman Converter with Class Topper Optimized PI Control in Sensorless BLDC Motor Drive for Electric Vehicle by Suresh V., Jahnavi V.G., Manjula D., Lokesh M.

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RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Osamu Yamanoshita, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Yoshiyuki Kawamoto, Masashi Kato

“…In human melanomas, the RAS/RAF/MEK/ERK (MAPK) and the PI3K/PTEN/AKT (AKT) signaling pathways are two major signaling pathways and are constitutively activated through genetic alterations. …”
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Molecular Alterations of PI3K/Akt/mTOR Pathway: A Therapeutic Target in Endometrial Cancer by Athanasia Pavlidou, Nikos F. Vlahos

“…It is well established that the PI3K/Akt/mTOR pathway plays a central role in cell growth and proliferation. …”
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LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis. by Lin Zhu, Qianqian Meng, Weiyi Qian, Weiting Shao, Yuyue Lu, Shuai Jin, Afei Zhang, Shuang G Yan, Jingtao Lu

“…Finally, through biological means such as RNA sequencing, flow cytometry, western blotting, and the construction of a subcutaneous tumorigenesis model in nude mice, we concluded that inhibition of HCC apoptosis by LARP3 is related to LARP3 negatively regulating ROS level and inhibiting the PI3K/c-Fos/apoptosis axis. This study will provide potential targets for the treatment of HCC.…”
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Analysis of somatic piRNAs in the malaria mosquito Anopheles coluzzii reveals atypical classes of genic small RNAs by Sergei Funikov, Alexander Rezvykh, Natalia Akulenko, Jiangtao Liang, Igor V. Sharakhov, Alla Kalmykova

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Penerapan Network Attached Storage (NAS) berbasis Raspberry Pi di LP3SDM AZRA Palembang by R.M. Nasrul Halim

“…Hasil dari penelitian ini berupa sistem penyimpanan data menggunakan Raspberry Pi sebagai file server pengganti PC, yang dapat melayani proses penyimpanan dan pertukaran data di LP3SDM AZRA Palembang sehingga dapat memudahkan pekerjaan karyawannya.   …”
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PTEN基因对子宫内膜癌细胞PI3K/AKT通路的影响

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Modification of P&O Method on MPPT with PI Controller to Reduce Power Oscillation during Steady-State Condition by Nisrina Rania Habibah, Rini Nur Hasanah, Zainul Abidin

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DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway by Rui Zhao, Mengran Wang, Zeyu Wu, Panpan Zhao, Huiling Dong, Yue Su, Chenghui Zhao, Min Qi, Shizhang Ling, Shizhang Ling, Xiaochun Jiang, Xiaochun Jiang

“…Western blot analysis further confirmed the downregulation of EGFR, JUN, and PI3K/AKT.ConclusionDET inhibits GBM cell invasion, proliferation, and apoptosis via modulating the PI3K/AKT signaling pathway, highlighting its potential as a novel therapeutic strategy for GBM treatment.…”
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