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Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer’s Disease Mice
Published 2022-01-01“…The molecular mechanism may involve activation of the PI3K/Akt/GSK-3β signaling pathway.…”
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Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway
Published 2019-01-01“…In both control and Cis-treated cells, AG treatment significantly increased PI3K/Akt/mTOR signaling and enhanced the nuclear accumulation of NF-κB. …”
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PPARγ Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling
Published 2018-01-01“…Conclusion. sGC/cGMP/PKG and PI3K/AKT signals act on PPARγ synergistically to attenuate hypoxia-induced HSC activation.…”
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646
The Evaluation of Tau Deposition with [18F]PI-2620 by Using a Semiquantitative Method in Cognitively Normal Subjects and Patients with Mild Cognitive Impairment and Alzheimer’s Disease
Published 2021-01-01“…Some studies have reported the effectiveness of [18F]PI-2620 as an effective tau-binding radiotracer; however, few reports have applied semiquantitative analysis to the tracer. …”
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647
A Combined MPC and PI Control Strategy for Bidirectional Interleaved Totem Pole PFC Converters in Electric Vehicle G2V and V2G Applications
Published 2025-01-01“…Meanwhile, the PI controller regulates the DC-side voltage. It is worth noting that the MPC’s design eliminates the need for a comparator to generate the Pulse Width Modulation (PWM) signal, simplifying the control architecture. …”
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Revisiting $$B\rightarrow K^*\pi $$ B → K ∗ π and $$B\rightarrow K\rho $$ B → K ρ decays using the modified perturbative QCD approach
Published 2025-02-01“…Abstract We revisit $$B\rightarrow K^*\pi $$ B → K ∗ π and $$B\rightarrow K\rho $$ B → K ρ decay processes using the modified perturbative QCD approach, which is developed based on the perturbative QCD approach with a few improvements. …”
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650
NLRP3 inflammasome activation and disruption of IRS-1/PI3K/AKT signaling: Potential mechanisms of arsenic-induced pancreatic beta cells dysfunction in rats
Published 2025-01-01“…Notably, these arsenic-induced effects were reversed by MCC950, an NLRP3 inflammasome inhibitor, and Extendin-4, an agonist of the IRS-1/PI3K/AKT signaling pathway. Collectively, these findings demonstrate that NLRP3 inflammasome activation disrupts the IRS-1/PI3K/AKT signaling pathway, contributing to arsenic-induced pancreatic beta cells dysfunction in rats.…”
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651
Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway
Published 2025-03-01“…These therapeutic effects are mediated through the activation of the PI3K/Akt/mTOR signaling pathway and regulation of apoptosis-related proteins. …”
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652
circSLC6A6 Sponges miR-497-5p to Promote Endometrial Cancer Progression via the PI4KB/Hedgehog Axis
Published 2021-01-01“…Besides, a mechanistic study demonstrated that circSLC6A6 could regulate tumor-associated signaling PI4KB/hedgehog pathway by sponging miR-497-5p. Conclusion. …”
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Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity
Published 2025-01-01“…This effect was mediated by the PI3K/Akt/NF-κB signaling pathway and could be reversed by the PI3K activator insulin-like growth factor-1 (IGF-1). …”
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Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells
Published 2022-01-01“…Molecularly, these metformin-stimulated M2 macrophages facilitated osteogenesis via activating the PI3K/AKT/mTOR pathway. As demonstrated by using PI3K-specific inhibitor LY294002, we found that the pathway inhibitor partly reversed osteoinductive activity which was activated by coculture of metformin-treated M2 macrophages. …”
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655
Quick Reference Guide to the Worker Protection Standard (WPS) as Revised in 2015
Published 2017-01-01Subjects: “…PI270…”
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656
Worker Protection Standard: Application Exclusion Zone (AEZ)
Published 2016-08-01Subjects: “…PI263…”
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657
Worker Protection Standard—Certified Crop Advisor Exemption
Published 2016-11-01Subjects: “…PI265…”
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658
Worker Protection Standard: Training Workers and Handlers under the 2016 Revision Requirements
Published 2016-11-01Subjects: “…PI268…”
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659
Worker Protection Standard: Personal Protective Equipment (PPE) 2016
Published 2016-11-01Subjects: “…PI267…”
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660
Quick Reference Guide to the Worker Protection Standard (WPS) as Revised in 2015
Published 2017-01-01Subjects: “…PI270…”
Get full text
Article