RNA-BioLens: A Novel Raspberry Pi-Based Digital Microscope With Image Processing for Acute Lymphoblastic Leukemia Detection by Angeline Dwi Sanjaya, Rachmad Setiawan, Nada Fitrieyatul Hikmah

Subjects: Get full text

Effects of IGF-1 on IK and IK1 Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes by Richard M. Millis, Zikiar V. Alvin, Aiqiu Zhao, Georges E. Haddad

“…IGF-1 contributes to cardiac hypertrophy via activation of PI3K/Akt signaling. However, the relationships between IGF-1, PI3K/Akt signaling and sarcolemmal potassium currents remain unknown. …”
Get full text

Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

Subjects: Get full text

PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer by Diyou Li, Yinglin Pan, Yating Huang, Ping Zhang, Xuhong Fang

“…These data suggested that PI3K induced epithelial-to-mesenchymal transition and promoted cell migration and invasion by activating the PI3K/AKT pathway in ovarian cancer. …”
Get full text

Role of PI3K/AKT/mTOR signaling pathway and sirtuin genes in chronic obstructive pulmonary disease development by G. F. Korytina, L. Z. Akhmadishina, V. A. Markelov, Y. G. Aznabaeva, O. V. Kochetova, T. R. Nasibullin, A. P. Larkina, N. N. Khusnutdinova, N. Sh. Zagidullin, T. V. Victorova

Subjects: Get full text

On the Recursive Sequence xn=1+∑i=1kαixn−pi/∑j=1mβjxn−qj by Stevo Stevic

“…We give a complete picture regarding the behavior of positive solutions of the following important difference equation: xn=1+∑i=1kαixn−pi/∑j=1mβjxn−qj, n∈ℕ0, where αi, i∈{1,…,k}, and βj, j∈{1,…,m}, are positive numbers such that ∑i=1kαi=∑j=1mβj=1, and pi, i∈{1,…,k}, and qj, j∈{1,…,m}, are natural numbers such that p1<p2<⋯<pk and q1<q2<⋯<qm. …”
Get full text

Alleviation of DSS-induced colitis by Meconopsis polysaccharides correlated with reduced PI3K/AKT signaling and gut microbiome diversity by Jun Dai, Weidong Wang, Fangfang He, Yujuan Wang, Denglang Zou

Subjects: Get full text

Pregnancy-Associated Plasma Protein A Induces Inflammatory Cytokine Expression by Activating IGF-I/PI3K/Akt Pathways by Weiping Li, Hongwei Li, Li Zhou, Zijian Wang, Bing Hua

“…Moreover, PAPP-A activated the IGF-I/PI3K/Akt signaling pathway in macrophages. The PAPP-A-mediated upregulation of MCP-1, TNF-α, and IL-6 mRNA and protein levels were strongly inhibited by PI3K inhibitors or IGF-IR siRNA, indicating that the upregulation of MCP-1, TNF-α, and IL-6 could involve the IGF-I/PI3K/Akt pathway. …”
Get full text

Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson’s Disease: Involvement of the PI3K/Akt/GSK3β Pathway by Wei Zhang, Hong He, Hujie Song, Junjie Zhao, Tao Li, Leitao Wu, Xiaojun Zhang, Jianzong Chen

“…These results show that Sal prevents the loss of dopaminergic neurons and the PI3K/Akt/GSK3β pathway signaling pathway may have mediated the protection of Sal against MPTP, suggesting that Sal may be a potential candidate in neuroprotective treatment for PD.…”
Get full text

Transition zone-based prostate-specific antigen density for differentiating clinically significant prostate cancer in PI-RADS score 3 lesions by Yongming Jin, Fei Chen, Gang Xu, Chaogang Wei, Congsong Dong

Subjects: Get full text

Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers by Feng Hao, Zhang Yan, Luo Shen, Wang Hui, Qiu Ling, Yang Xiaoyu, Jiang Hua

Subjects: Get full text

Development of novel nomograms for predicting prostate cancer in biopsy-naive patients with PSA < 10 ng/ml and PI-RADS ≤ 3 lesions by Jia-gui Chai, Yu-hang Li, Chang-xing Ke

Subjects: Get full text

冬凌草甲素作用PI3K/AKT通路诱导HeLa细胞凋亡 by 沈宏伟, 胡红珍, 曾海涛, 柯佩琪, 杨越波, 李小毛, 任姿

Get full text

Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells by Ju-Young Kim, Ho Kim, Kyoungho Suk, Won-Ha Lee

“…CD147-induced expression of IFITM1 was blocked by inhibitors of ERK, PI3K, or NF-κB, but not by inhibitors of p38, JNK, or PKC. …”
Get full text

Lignans from Patrinia scabiosaefolia improve insulin resistance by activating PI-3K/AKT pathway and promoting GLUT4 expression by Zhenhua Liu, Mengke Wang, Lijun Meng, Yixiao Chen, Qiuyi Wang, Yan Zhang, Xuefeng Xi, Wenyi Kang

“…Therefore, the mechanisms of compounds 2 and 4 were presumed to improve IR by activating PI-3K/AKT signaling pathway.…”
Get full text

Mejoramiento genético de alpiste: selección y evaluación de líneas de derivadas de la población marroquí PI284184 by M. Cogliatti, L.V. Cortizo, W.J. Rogers

“…Así, se identificó una población marroquí, denominada PI 284184, que exhibió un adecuado comportamiento agronómico. …”
Get full text

Flavonoids of Tetrastigma hemsleyanum Diels et Gilg Against Acute Hepatic Injury by Blocking PI3K/AKT Signaling Pathway by Lingling Li, Lianghui Zhan, Xiaojun Wu, Xuechun Jiang, Jinbao Pu

“…Conclusion: The treatment of acute liver injury with THF is characterized by multicomponents and multitargets, and its mechanism may be related to the alleviation of the inflammatory response, reduction of apoptosis, and regulation of the PI3K/AKT signaling pathway.…”
Get full text

Ascophyllum nodosum and Fucus vesiculosus ameliorate restenosis via improving inflammation and regulating the PTEN/PI3K/AKT signaling pathway by Crystal Ngofi Zumbi, Chun-Hsu Pan, Hui-Yu Huang, Chieh-Hsi Wu

Subjects: Get full text

ＰＩＧＦ、ｓＶＥＧＦＲ－１、ＮＯ联合ＰＩ对高危孕妇发生子痫 前期的预测

“…摘 要： 【目的】 探讨血清胎盘生长因子（ＰＩＧＦ）、可溶性血管内皮生长因子受体－１（ｓＶＥＧＦＲ－１）、一氧化氮（ＮＯ）浓度联合子宫动脉搏动指数（ＰＩ）在高危孕妇中预测子痫前期发生的价值。【方法】 收集１６２例具有子痫前期高危因素孕妇妊娠２２～２６周时的血清标本，应用酶联免疫吸附试验（ＥＬＩＳＡ）检测ＰＩＧＦ及ｓＶＥＧＦＲ－１浓度，比色法检测ＮＯ浓度，同期行子宫动脉多普勒超声检查测定ＰＩ值。…”
Get full text

Retracted: miR-29c Inhibits Renal Interstitial Fibrotic Proliferative Properties through PI3K-AKT Pathway by Applied Bionics and Biomechanics

Get full text