PICT: A low‐cost, modular, open‐source camera trap system to study plant–insect interactions by Vincent Droissart, Laura Azandi, Eric Rostand Onguene, Marie Savignac, Thomas B. Smith, Vincent Deblauwe

“…We developed PICT (plant–insect interactions camera trap), an inexpensive (<100 USD) do‐it‐yourself CT system based on a Raspberry Pi Zero computer designed to continuously film animal activity. …”
Get full text

基于线粒体Cyt b基因和CR序列的养殖貉（Nyctereutes procyonoides）种群遗传多样性和结构分析 by 魏宏达 李波 魏来 刘志平 姜春明 史迎秋 徐艳春

“…种群遗传多样性分析表明，养殖貉种群单倍型多样性处于临界点（Hd=050）、核苷酸多样性处于较高水平（Pi>05%），但二者均明显低于俄罗斯野生乌苏里貉种群。这种遗传多样性模式可能主要是由奠基者效应（founder effect）导致的。…”
Get full text

Multitask Learning-Based Pipeline-Parallel Computation Offloading Architecture for Deep Face Analysis by Faris S. Alghareb, Balqees Talal Hasan

“…A computation offloading approach, on the other hand, is leveraged to distribute computation-intensive tasks to the server edge, whereas lightweight computations are offloaded to edge devices, i.e., Raspberry Pi 4. To train the proposed deep face analysis network architecture, two custom datasets (HDDB and FRAED) were created for head detection and face-age recognition. …”
Get full text

铅对肾上腺皮质细胞线粒体的氧化损伤 by 杨杏芬, 庄志雄, 魏　青, 凌　莉, 范瑞泉

“…ROS 检测采用荧光分光光度法, 线粒体膜电位(MMP)和细胞存活状态采 用Rh123 和PI 双标记、流式细胞术检测, 细胞ATP 水平采用化学发光法测定。【结果】PbAc 染毒后肾上腺皮质细胞ROS 形 成水平随剂量增加而增加, 具有剂量效应关系[ y =4.16 +10.21 ×1g(x +1), P <0.01 , R 2 =0.641] ;线粒体膜电位呈剂量 依赖性降低, Rh123 的平均荧光强度(MFI)在6.25 ～ 100 μmol/ L 各剂量组依次为1.01, 0.94, 0.96 , 0.95 和0.91, 与对照组 (1.35)比较具有显著性差异(P <0.01);染毒后细胞死亡率轻度增加, 与对照组(1.02%)比较, 50 μmol/ L 和100 μmol/L 的 PbAc 组分别为3.16%和3.40%, 差异具有显著性(P <0.05);ATP 水平降低与PbAc 剂量之间存在剂量效应关系[ y = 212965.7-51592.5 ×1g( x +1), P <0.01 , R 2 =0.568] , 剂量和时间对ATP 水平的影响呈协同抑制作用(P <0.01)。…”
Get full text

Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology by Francesca Caso, Benno Gesierich, Maya Henry, Manu Sidhu, Amanda LaMarre, Miranda Babiak, Bruce L. Miller, Gil D. Rabinovici, Eric J. Huang, Giuseppe Magnani, Massimo Filippi, Giancarlo Comi, William W. Seeley, Maria Luisa Gorno-Tempini

“…Five years after her first evaluation, she developed mild memory impairment and underwent PET-FDG and PiB scans that showed left frontal hypometabolism and cortical amyloidosis. …”
Get full text

Oral cannabidiol did not impair learning and memory in healthy adults by Hanna H. Gebregzi, Joanna S. Zeiger, Jeffrey P. Smith, Libby Stuyt, Luann Cullen, Jim Carsella, Daniel C. Rogers, Jordan Lafebre, Jennah Knalfec, Alfredo Vargas, Moussa M. Diawara

“…However, a highly significant interaction effect between treatment groups (CBD vs. placebo) and age of subjects was observed for the PI ratio (P = 0.008; n = 35). Conclusions The results of this study suggest that administration of oral CBD alone does not significantly impair L&M in healthy adults. …”
Get full text

Autoregulatory Feedback Mechanism of P38MAPK/Caspase-8 in Photodynamic Therapy-Hydrophilic/Lipophilic Tetra-α-(4-carboxyphenoxy) Phthalocyanine Zinc-Induced Apoptosis of Human Hepa... by Yu Wang, Chunhui Xia, Wei Chen, Yuhang Chen, Yiyi Wang, Tao Li

“…In the present study, therefore, effect of TαPcZn-PDT on apoptosis, P38MAPK, p-P38MAPK, Caspase-8, Caspase-3, Bcl-2, Bid, Cytochrome c, and mitochondria membrane potential in Bel-7402 cells without or with P38MAPK inhibitor SB203580 or Caspase-8 inhibitor Ac-IEFD-CHO was investigated by haematoxylin and eosin (HE) staining assay, flow cytometry analysis of annexin V-FITC/propidium iodide (PI) double staining cells and 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide (JC-1), and immunoblot assay. …”
Get full text

An Integrated Stacking Ensemble Model for Natural Gas Purchase Prediction Incorporating Multiple Features by Junjie Wang, Lei Jiang, Le Zhang, Yaqi Liu, Qihong Yu, Yuheng Bu

“…The model was subsequently applied to predict natural gas purchase volumes in Pi County, Chengdu, China. In November 2024, a side-by-side comparison of the predicted and actual data revealed a maximum error of just 5.39%. …”
Get full text

三嵌段聚合物搭载藻蓝蛋白对人晶状体上皮细胞氧化损伤的保护作用 by 陈梦婷, 郝莉莉, 刘莲, 陈填烽, 钟敬祥

“…【方法】构建并纯化三嵌段聚合物搭载藻蓝蛋白，并建立AAPH诱导人晶状体上皮细胞氧化损伤模型；实验分为正常对照组、AAPH损伤组、PPP-PC+AAPH处理组，分别进行相应处理后，通过荧光倒置显微镜观察各组细胞形态及活力；应用AnnexinV-FITC/PI双染法流式细胞仪检测各组细胞凋亡比例；蛋白免疫印迹法检测各组细胞Bax、Bcl-2和Caspase-3凋亡相关蛋白的表达水平。…”
Get full text

Akkermansia muciniphila Enhances the Antitumor Effect of Cisplatin in Lewis Lung Cancer Mice by Zhuo Chen, Xiang Qian, Shasha Chen, Xiaoxuan Fu, Guanjun Ma, Aiqin Zhang

“…In addition, transcriptome analysis indicated that Akk combining with CDDP increased obviously the levels of IFI27l2 and IGFBP7 and was related to those pathways including the cytokine-cytokine receptor interaction, Th17 cell differentiation, FOXO, JAK-STAT, and PI3K-Akt signaling pathways. These results suggested that the therapeutic efficacy of the combined treatment of Akk and CDDP was superior to the only CDDP treatment, which could enhance immune regulation and would be a promising strategy for the treatment of lung cancer.…”
Get full text

Lower Hemoglobin Concentration Is Associated with Retinal Ischemia and the Severity of Diabetic Retinopathy in Type 2 Diabetes by Alicia Traveset, Esther Rubinat, Emilio Ortega, Nuria Alcubierre, Beatriz Vazquez, Marta Hernández, Carmen Jurjo, Ramon Espinet, Juan Antonio Ezpeleta, Didac Mauricio

Get full text

Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular flui... by Chong Wang, Ying Feng, Yu Chen, Xianhua Lin, Xiangjuan Li

“…The OSM signaling pathway, the IL-10 anti-inflammatory signaling pathway, and the PI3K−Akt signaling pathway are three notable pathways involved in affecting ovarian reserve capacity according to bioinformatics analysis. …”
Get full text

G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz

“…Here, employing ERα-negative Hec50 endometrial cancer cells, we demonstrate that GPER mediates estrogen-stimulated activation of ERK and PI3K via matrix metalloproteinase activation and subsequent transactivation of the EGFR and that ER-targeted therapeutic agents (4-hydroxytamoxifen, ICI182,780/fulvestrant, and Raloxifene), the phytoestrogen genistein, and the “ERα-selective” agonist propylpyrazole triol also function as GPER agonists. …”
Get full text

Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress by Siyuan Luo, Junnan Li, Yuqing Zhou, Zihang Zhai, Qiang Li, Zhenglin Huang, Wencan He, Kejun Zhong, Bo Kong, Zanxian Xia, Hang Fai Kwok, Lipeng Zhu

“…C. elegans exposed to DIOP exhibit increased oxidative stress, evidenced by higher ROS levels and lipofuscin buildup. Importantly, the PI3K/AKT and MAPK pathways are implicated in the response to DIOP-induced toxicity. …”
Get full text

Metagenomics and Faecal Metabolomics Integrative Analysis towards the Impaired Glucose Regulation and Type 2 Diabetes in Uyghur-Related Omics by Rebiya Nuli, Jureti Azhati, Junxiu Cai, Aizhatiguli Kadeer, Bing Zhang, Patamu Mohemaiti

“…Alchornoic acid, PE (14 : 0/20 : 3), PI, L-tyrosine, LysoPC (15 : 0), protorifamycin I, pimelic acid, epothilone A, 7-dehydro-desmosterol, L-lysine, LysoPC (14 : 1), and teasterone are the most significant differential enriched metabolites. …”
Get full text

Effects of L-carnitine and pentoxifylline on long-term preservation of the human sperms: An experimental study by Elham Aliabadi, Zohre Nateghian, Mohammad Hossein Nasr-Esfahani, Marziyeh Tavalaee, Tahereh Talaei-Khozani

“…The percentages of the sperms with double-stranded DNA, apoptotic, and acrosomal interacted sperms were evaluated by sperm chromatin structure assay, AnnexinV-PI staining, and peanut agglutinin, respectively. …”
Get full text

A Low Complexity Dual-Phase Alternating Scheme is Used With the PTS Method to Reduce PAPR for B5G Systems by Yung-Ping Tu, Chen-Wei Hsu

“…In the second stage, we use the dual-phase alternation of 0 and <inline-formula> <tex-math notation="LaTeX">$\pi $ </tex-math></inline-formula> radian to wimple the effect of the peaking power of each subcarrier on PAPR one by one until the estimated amount <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>. …”
Get full text

Posterior instrumented correction and fusion of Scheuermann´s results in physiological reconstruction of sagittal alignment and excellent overall clinical outcome- clinical trail o... by M.-L. Jensch, U. Platz, M. Quante, M. Köszegvary, B. Thomsen, J. Gliemroth, C. Berlin, H. Halm

“…Whole spine x-rays were analyzed (preop, postop, after 6, 12, 24 months): sagittal and coronary Cobb angles, and pelvic parameters were evaluated; ideal lumbar lordosis (LL) was calculated using formula of le Huec (LL = 0.54*PI + 27.6). Surgical time, complications and blood loss were compared. …”
Get full text

Altered expression profile of plasma exosomal microRNAs in exclusive electronic cigarette adult users by Dongmei Li, Zidian Xie, Sadiya Bi Shaikh, Irfan Rahman

“…KEGG pathway analysis indicated their involvement in cancer pathways, including small cell lung cancer, renal cell carcinoma, and signaling pathways (neurotrophin, ErbB, PI3K-Akt, FoxO, Hippo, MAPK, TGF-beta). Overexpression of hsa-miR-125b-5p promoted DNA damage in bronchial epithelial cells. …”
Get full text

Effect of non-surgical periodontal therapy on salivary and gingival crevicular fluid concentration of visfatin in periodontal health and disease by Hira Ismail, Anjani Kumar Pathak, Nand Lal, Pavitra Rastogi, Kaleem Ahmad, Mohd. Aamir Khan

“…The objective of the present study was to assess the impact of non-surgical periodontal therapy (scaling and root planing) on visfatin concentrations in saliva and gingival crevicular fluid in individuals with Periodontitis (stage-II grade-A) Materials and methods: 54 individuals were divided into Group A (Periodontally Healthy) and Group B1(Periodontitis baseline) based on periodontal parameters including plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), and radiographic parameters. …”
Get full text