马鹿<italic>CDK8</italic>基因生物信息学分析与组织表达 by 唐成怡, 吴玄烨, 吴尽, 杨帆, 刘学东

“…结果表明：马鹿<italic>CDK8</italic>的CDS全长1 254 bp，共编码417个氨基酸；所编码的蛋白相对分子质量为47 744.11，理论等电点（pI）为7.28，是一种无信号肽、定位于细胞核的亲水性不稳定蛋白，共38个磷酸化位点，蛋白的二级结构以无规则蜷曲和<italic>α</italic>螺旋为主。…”
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The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells by Lijun Wang, Luqun Tang, Chengyun Yao, Chunyan Liu, Yongqian Shu

“…The results from Annexin V/PI staining and flow cytometry analysis suggested that celastrol enhanced tamoxifen-mediated apoptosis. …”
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Accelerating Deep Learning-Based Morphological Biometric Recognition with Field-Programmable Gate Arrays by Nourhan Zayed, Nahed Tawfik, Mervat M. A. Mahmoud, Ahmed Fawzy, Young-Im Cho, Mohamed S. Abdallah

“…The software programming on the Raspberry Pi-3B kit had a recognition accuracy of around 70–75% and relied on a stable internet connection for processing. …”
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Identifying common pathways for doxorubicin and carfilzomib-induced cardiotoxicities: transcriptomic and epigenetic profiling by Conagh Kelly, Dylan J. Kiltschewskij, Angeline J.W. Leong, Tatt Jhong Haw, Amanda J. Croft, Lohis Balachandran, Dongqing Chen, Danielle R. Bond, Heather J. Lee, Murray J. Cairns, Aaron L. Sverdlov, Doan T. M. Ngo

“…Pathway analysis revealed that the PI3K-Akt signalling pathway was the most significantly enriched pathway with common DEGs, shared between Doxorubicin and Carfilzomib. …”
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SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1 by Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin

“…Cell cycle progression was analyzed using propidium iodide (PI) staining, and protein levels were assayed by Western blot analysis. …”
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ANÁLISIS DE LAS RELACIONES COMERCIALES ENTRE IBEROAMÉRICA Y EL CARIBE Y LA UNIÓN EUROPEA (1992-2003) by Eduardo Cuenca García, José Antonio Rodríguez Martín

“…En este tra ba jo pre sen ta mos una va lo ra ción em pí ri ca de la evo lu ción de las re la cio nes co mer cia les en tre Ibe ro amé ri ca y el Ca ri be y la Unión Eu ro pea en tre 199 2 y 200 3, de acue r do con los da tos dis po ni bles re cien tes, cen trán donos en su vo lu men, la con cen tra ción por paí ses y áreas y las fa ses por las que ha atra ve sa do, en el mar co de los prin ci pa les acuer dos in tra rre gio na les y la cre cien te li be ra ción de sus eco no mías. …”
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Molecular Mechanisms and Therapeutic Prospects of Immunotherapy and Targeted Therapy in Primary Central Nervous System Lymphoma by Lin Zhong MM, Anqing Lu MB, Xiyue Lu MM, Xiaoyin Liu MD, Lujia Cao MM, Shihong Zhu MM, SiJun Diao MM, Xu Cheng MM, Hongwei Wu MB, Jing Chen MD

“…With a deeper understanding of the pathophysiology of PCNSL, various therapies, including CD20 monoclonal antibodies, Bruton's tyrosine kinase (BTK) inhibitors, immunomodulatory drugs, immune checkpoint inhibitors, phosphoinositide 3-kinase (PI3 K)/mammalian target of rapamycin(mTOR) inhibitors, and chimeric antigen receptor (CAR) -T cells are increasingly being applied and have demonstrated considerable efficacy. …”
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RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells by Hangyu Xu, Qing Yin, Linna Fan, Yating Zhao, Biying Song, Qifan Xu, Jie Zhu, Meifen Xu

“…We further indicated that in 5–8 F cells following RNF138 overexpression, some pathways such as PI3K-Akt signaling pathway, human papillomavirus infection and ErbB signaling pathway that have been reported to be associated with NPC progression and cisplatin resistance were significantly enriched. …”
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Transcript Changes of Placental Tissue in Gestational Diabetes Mellitus Based on Transcriptome Sequencing by Sun Y, Wang Y, Liu C, Yang J, Li Q, Zhao F

“…KEGG pathway enrichment analysis indicated the involvement of DEGs in signalling pathways related to PI3K-Akt signaling pathway and ECM-receptor interaction. qRT-PCR validation of five randomly selected DEGs confirmed consistent expression trends with RNA-Seq quantification.Conclusion: YWHAB, LEP, CCL21, PAPPA2, and SFN may be potential biological markers for the diagnosis of GDM, involved in the occurrence and development of GDM, and have certain value for disease prediction and diagnosis.Keywords: gestational diabetes, transcriptome sequencing, qRT-PCR validation, placental tissue, pathogenic genes…”
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Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats by Emmanuel Nnaemeka Uhuo, Simeon Ikechukwu Egba, Chiemeziem Adnma Obike, Paul Ndubuisi Anyiam, Prince Ogochukwu Alaebo, Pryanka Munachiso Okeke, Emmanuella Chinaza Obinali

“…Abbreviations: BPH: benign prostatic hyperplasia; CAT: catalase; DTH: dihydrotestosterone; GPx: glutathione peroxidase; HDL-Chol: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; MDA: malondialdehyde; NC: normal control; PI: prostatic interstitium; PVC: packed cell volume; PSA: prostate specific antigen; SOD: superoxide dismutase; TP: testosterone propionate; TAG: triacylglycerol…”
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Induced resistance to the greenbug aphid Schizaphis graminum Rond. in species of the genus Triticum by S. D. Rumyantsev, S. V. Veselova, G. F. Burkhanova, I. V. Maksimov

“…We investigated the expression of genes encoding PR proteins, including markers and regulators of the salicylate (TaRboh, TaPAL, Tapr1, TaPrx) and jasmonate (TaPI, TaLOX, TaPrx) signaling pathways. At the early stage of infestation in the susceptible T. aestivum variety Salavat Yulaev, the expression of only jasmonate-dependent genes was activated in response to plant damage. …”
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Expression Profile of Long Noncoding RNAs and Circular RNAs in Mouse C3H10T1/2 Mesenchymal Stem Cells Undergoing Myogenic and Cardiomyogenic Differentiation by Mingshan Li, Zijie Pei, Hongtao Zhang, Jing Qu

“…Moreover, the differentially expressed mRNAs were enriched into 5 significant pathways, including those for focal adhesion, ECM-receptor interaction, PI3K-AKT signaling pathway, PPAR signaling pathway, and Tyrosine metabolism. …”
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Anticancer properties of Dillenia suffruticosa (Griffith Ex. Hook. F. &amp; Thomsom) Martelli by Ika Rahayu, Susana Elya Sudrajat, Kris Herawan Timotius

“…These extracts inhibit cancer cell growth, induce apoptosis, and target pathways like p53/p21, JNK, PI3K/AKT, and NFκB, with effects linked to mitochondrial dysfunction. …”
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Detection and decontamination of Mycoplasma in cultured cells and viral strains by Glaucia Prado de Andrade, Natália Hettwer Pedroso, Alice Becker, Vinicius Soares dos Santos, Juciane Bonella, José Valter Joaquim Silva Júnior, Rudi Weiblen, Eduardo Furtado Flores

“…Fourteen bovine viral strains were also found contaminated, including three bovine viral diarrhea virus 1 (BVDV-1), two BVDV-2, four bovine alphaherpesvirus 1 (BoHV-1), one each: HoBiPeV, BoHV-2, BoHV-5, bovine parainfluenza virus 3 (bPI-3V) and bovine respiratory syncytial virus (BRSV). …”
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Мutants of inflorescence development in alfalfa (Medicago sativa L.) by N. I. Dzyubenko, E. A. Dzyubenko

“…New gene  names  are proposed for new duplex  and triplex mutant types: lpfas, pi1lpfas, brilpfas. Medicago truncatula is a conventional model species for legume  genome research. …”
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Identification and Genetic Diversity Analysis of Cinnamomum parthenoxylon (Jack) Meisn Species in Song Hinh Protection Forest, Vietnam Based on Three Chloroplast Gene Regions by Dinh Duy Vu, Mai Phuong Pham, Ngoc Huyen Dang, Xuan Dac Le, Hung Cuong Dang, Huu Thuc Nguyen, Dang Hoi Nguyen

“…The genetic variations in C. parthenoxylon were moderate, with an average number of nucleotide differences (Kt = 1.042–4.984), haplotype diversity (Hd = 0.521–0.916), and nucleotide diversity (Pi = 1.33–10.74 × 10–3). Conclusions: The results of this study have the potential to provide valuable information that is essential for the classification, and identification of the plant’s origin, propagation, and conservation program of C. parthenoxylon in Vietnam.…”
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Effect of Essential Microelements on Proteomic Profile of Lamb Muscle Tissue Protein by Tatiana M. Giro, Andrey V. Kulikovsky, Anna V. Giro

“…Major protein fractions included eight with a molecular weight of 12–15 kDa, 42 with 16–30 kDa, and 45 with 35–110 kDa (pI 5.0–8.0). The samples contained glutathione-S-transferase, which is responsible for biotransformation of toxic compounds, maintenance of intracellular homeostasis, and stress resistance. …”
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Correlation of serum C - reactive protein with clinical parameters in diabetic patients having chronic periodontitis before and after treatment by Arkhawan Ali Abdulhaq, Ziwar Ahmed Salih, Solaf Abdulqadir Mustafa

“…Results: at base line, type II diabetes mellitus patients group I (T2DMCP) were compared to the non-diabetic patients with chronic periodontitis group II (NDMCP) based on the clinical periodontal parameters (GI,PPD, CAL and PI )scores and CRP level, HBA1c , (RBS) with the 3months after treatment. …”
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Extensive composable entropy for the analysis of cosmological data by Constantino Tsallis, Henrik Jeldtoft Jensen

“…For this W(N) asymptotic behavior, we make use of the group-theoretic entropic functional Sα,γ=k[ln⁡Σi=1Wpiα1−α]1γ(α∈R;S1,1=SBG≡−k∑i=1Wpiln⁡pi), first derived by P. Tempesta in Chaos 30,123119, (2020). …”
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A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis by Nasibeh Khayer, Samira Shabani, Maryam Jalessi, Mohammad Taghi Joghataei, Frouzandeh Mahjoubi

“…The results highlighted the “PI3K/AKT/mTOR (PAM) signaling pathway” as a disrupted pathway involved in the metastatic nature of HNSCC. …”
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