Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after I... by Kaiwen Luo, Mengdie Wang, Xiangxiang Pan, Yadong Xing

“…The Tmax, AUC, and Cmax of three ingredients in CUMS-induced depression rats were significantly larger than control rats, while these pharmacokinetic parameters in CUMS + ZZHPD treatment rats were decreased significantly compared with CUMS-induced depression rats, which may relate with the changes in physiological function of the gastrointestinal tract and liver in CUMS-induced liver-stagnation and spleen-deficiency syndrome depressive rats. …”
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Nanomechanical characterization of soft nanomaterial using atomic force microscopy by Chi-Dat Lam, Soyeun Park

“…AFM is widely used in biological and pharmaceutical sciences because it can scrutinize mechanical properties under physiological conditions. We comprehensively reviewed experimental techniques and fundamental mathematical models to investigate the mechanical properties, including elastic moduli and binding forces, of soft materials.To determine these mechanical properties, two-dimensional arrays of force-distance (f-d) curves are obtained through AFM indentation experiments using the force volume technique. …”
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Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages. by Judith A Smith, Mike Khan, Diogo D Magnani, Jerome S Harms, Marina Durward, Girish K Radhakrishnan, Yi-Ping Liu, Gary A Splitter

“…These results also have implications for other intracellular bacteria that rely on host physiologic stress responses for replication.…”
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Comparison of the Cognitive Skills of Adolescent Basketball Players and Sedentary Adolescents by Egemen Mancı, Fırat Özdalyan, Sercin Kosova, Hikmet Gümüş, Celal Gençoğlu

“…Chronic exercise provides a physical and physiological improvement, while also supporting cognitive development significantly. …”
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Cirrhotic cardiomyopathy by S. N. Mammayev, A. M. Karimova, T. E. Il’yasova, A. Sh. Khasayev

“…Results of numerous studies showed suppression of contractile response to action of various physiological and pharmacological stimuli, and disorder of diastolic function of the heart, development of electrophysiological, structural and biochemical changes at LC irrespective of its origin. …”
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Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord by Yali Chen, Yiyong Wei, Jin Liu, Tao Zhu, Cheng Zhou, Donghang Zhang

“…Glial cells play crucial roles in regulating physiological and pathological functions, including sensation, the response to infection and acute injury, and chronic neurodegenerative disorders. …”
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Prevalence of Tactile Hallucination of Phone Vibration among Individuals Aged 18–22 Years by Tanisha Sunil Mali, Trupti Yadav

“…Background: Overuse of phones can lead to physiological health hazards. The repeated use of vibration mode leads to fake perception of device being vibrating when it is not. …”
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Longitudinal validation of King's Sarcoidosis Questionnaire in a prospective cohort with mild sarcoidosis by Janne Møller, Thomas Skovhus Prior, Ole Hilberg, Surinder Birring, Elisabeth Bendstrup

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REGAIN STUDY: Retrospective Study to Assess the Effectiveness, Tolerability, and Safety of Ferric Carboxymaltose in the Management of Iron Deficiency Anemia in Pregnant Women by Saleema Wani, Mariyam Noushad, Shabana Ashiq

“…Iron deficiency anemia (IDA) during pregnancy arises because of preexisting inadequate stores or complex physiological changes and can lead to serious maternal and fetal complications. …”
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PATHOPHYSIOLOGIC MECHANISMS OF THE INFLUENCE OF TISSUE RESPIRATION ENZYMES ON THE MITOCHONDRIAL FUNCTION IN PATIENTS WITH CHRONIC HEPATITIS C by I.Y. Bagmut, S.M. Gramatiuk

“…Mitochondrial division is a key determinant of mitochondrial quality control, and HCV modulates these key processes in the adaptation to cellular physiological perturbations associated with infection to promote viral persistence. …”
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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. by Liam C Hunt, Michelle Curley, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth R Pagala, Junmin Peng, Fabio Demontis

“…Likewise, human UBE2D2 partially rescues the lifespan and proteostasis deficits caused by muscle-specific effRNAi and re-establishes the physiological levels of effRNAi-regulated proteins. Interestingly, UBE2D/eff knockdown in young age reproduces part of the proteomic changes that normally occur in old muscles, suggesting that the decrease in UBE2D/eff protein levels that occurs with aging contributes to reshaping the composition of the muscle proteome. …”
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Reconstruction of U.S. Regional-Scale Soybean SIF Based on MODIS Data and BP Neural Network by YAO Jianen, LIU Haiqiu, YANG Man, FENG Jinying, CHEN Xiu, ZHANG Peipei

“…Because of the multisource remote sensing dataset encompassed the most relevant explanatory variables within each SIF footprint coverage area concerning soybean physiological structure and environmental conditions. …”
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Stimulation of gonad maturation in mullet fish Mugil dussumieri using MT, E2, hCG, and Ovaprim hormone by Tatak Dwi Cahyono, Muhammad Zairin Junior, Odang Carman

“…First experiment used 9-14.7 cm body length of fish treated with different hormone injections i.e. 4 mg/kg 17α-methyltestosterone (MT), 0.07 mg/kg estradiol-17β (E2), and 0.5 ml/kg 0.9% physiological solution as control. Second experiment used 10-31 cm body length fish treated with 750 IU/kg chorionic gonadotropin (hCG), 0.5 ml/kg Ovaprim, and 0.9% physiological solution as control. …”
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Prophylactic Ozone Administration Reduces Intestinal Mucosa Injury Induced by Intestinal Ischemia-Reperfusion in the Rat by Ozkan Onal, Fahri Yetisir, A. Ebru Salman Sarer, N. Dilara Zeybek, C. Oztug Onal, Banu Yurekli, H. Tugrul Celik, Ayse Sirma, Mehmet Kılıc

“…Control group was administered serum physiologic (SF) intraperitoneally (ip) for five days. …”
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Gestational - age - specific reference intervals for blood pressure in normal pregnancy in a Southern Chinese population by Yuguo Deng, Lanfang Liang, Ying Gao, Guilian Liao, Qiaozhu Chen, Zijian Huang, Jinying Yang

“…Abstract Objective Physiological blood pressure changes in pregnancy are insufficiently defined. …”
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Addressing challenges in pediatric thrombosis: a comprehensive guideline development by Yin Wang, Qinan Yin, Jiangting Liao, Na Wang, Li Li, Siyan Li, Qingxia Zhang, Feifei Yu, Jianchun Luo, Hongmei Wang, Die Hu, Wenyi Li, Biao Li, Jingjing Chen, Limei Dong, Min Luo, Yu Yan, Lie Dong, Zheng Ding, Xi Wei, Jiadan Yang, Shenglan Tan, Lian Li, Xi Zheng, Liuyun Wu, Yong Yang, Linan Zeng, Jinqi Li, Lizhu Han, Yuan Bian

“…Due to significant physiological differences between children and adults, guidelines for the prevention and treatment of thrombotic diseases in adults cannot be directly applied to pediatric patients.PurposeA systematic review of the existing evidence-based medical literature should be conducted to propose pharmacological prevention and treatment recommendations for pediatric thrombotic diseases. …”
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Influence of Coating Application Methods on the Postharvest Quality of Cassava by Loreto Atieno, Willis Owino, Elijah M. Ateka, Jane Ambuko

“…This study aimed at determining the most efficient coating application method on the cassava postharvest quality. Physiologically mature cassava (variety KME 1) was harvested and divided into seven portions. …”
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A Novel Approach to Optimize Key Limitations of Azure Kinect DK for Efficient and Precise Leaf Area Measurement by Ziang Niu, Ting Huang, Chengjia Xu, Xinyue Sun, Mohamed Farag Taha, Yong He, Zhengjun Qiu

“…Maize leaf area offers valuable insights into physiological processes, playing a critical role in breeding and guiding agricultural practices. …”
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Effectiveness of the addition of visual aids to conversational preoperative education in glaucoma filtering surgery: A randomized controlled trial by Peimin Lin, Laiwen Lv, Ruqing Tang, Dehua Li, Xiaoxuan Chen, Jie Fang, Zhenggen Wu, Chukai Huang, Kusheng Wu

“…Interpretation: The inclusion of visual aids in preoperative education significantly improves patient outcomes in glaucoma filtering surgery by reducing anxiety and pain and stabilizing physiological parameters. This approach is particularly beneficial for patients with lower educational backgrounds.…”
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The AEDUCATE Collaboration. Comprehensive antenatal education birth preparation programmes to reduce the rates of caesarean section in nulliparous women. Protocol for an individual... by Soo Downe, Lisa Askie, Sarah J Lord, Hannah G Dahlen, Kenneth William Finlayson, Anna Lene Seidler, Federico Girosi, Kylie Elizabeth Hunter, Kate M Levett, Mary-Ann Davey, Caroline A Smith, Julie Fleet, Mary Steen, Elizabeth Newnham, Anette Werner, Leslie Arnott, Kerry Sutcliffe

“…Methods and analysis Population: women with singleton vertex pregnancies, no planned caesarean section (CS) or epidural.Intervention: in addition to hospital-based standard care, a comprehensive antenatal education programme that includes multiple components for birth preparation, addressing the three objectives: preparing women and their birth partner/support person for childbirth through education on physiological/hormonal birth (knowledge and understanding); building women’s confidence through psychological preparation (positive mindset) and support their ability to birth without pain relief using evidence-based tools (tools and techniques). …”
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