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6701
Health Risk Assessment of Chemicals: From Bulk to Nano
Published 2024-12-01“…EPA Model, Monte-Carlo Simulation, Physiologically Based Pharmacokinetic (PBPK) Modeling, Quantitative Structure-Activity Relationship (QSAR) Models, Probabilistic Risk Assessment (PRA), Life Cycle Impact Assessment (LCIA), and Biologically Based Dose-Response (BBDR) Models, are among the most important quantitative methods for assessing the health risk of chemicals. …”
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6702
Changes in the Structural and Functional Albumin Properties in Patients with Decompensated Liver Cirrhosis
Published 2023-06-01“…There were not only serum concentration depletion in cirrhotic patients, but also albumin physiological non-oncotic properties were violated. The severity of these changes increased with the progression of cirrhosis. …”
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6703
Hemodynamic and Lesion Characteristics Associated with Discordance between the Instantaneous Wave-Free Ratio and Fractional Flow Reserve
Published 2019-01-01“…The instantaneous wave-free ratio (iFR) is an invasive coronary physiological index that is not inferior to fractional flow reserve- (FFR-) guided revascularization. …”
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6704
Chemical Composition, In Vivo, and In Silico Molecular Docking Studies of the Effect of <i>Syzygium aromaticum</i> (Clove) Essential Oil on Ochratoxin A-Induced Acute Neurotoxicity
Published 2025-01-01“…The aim of our research was to understand the impact of ochratoxin A (OTA) exposure on various physiological and behavioral aspects in adult Wistar rats, and to evaluate the efficacy of a <i>Syzygium aromaticum</i> essential oil (EOC) treatment in restoring the damage caused by this toxin. …”
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6705
Proteomic evaluation of pathways associated with phosphine-induced mitochondrial dysfunction and resistance mechanisms in Tribolium castaneum against phosphine fumigation: Whole an...
Published 2025-01-01“…Upregulation of aldose reductases involved in polyol pathways and downregulation of the trehalose transporter were observed, suggesting that PH3-resistance may be linked to diapause-like physiological adaptations, including quiescence. Further studies are essential to quantify polyol levels in the AUS-07 strain and to conduct other molecular analyses to validate the roles of identified DEPs in PH3 resistance. …”
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6706
Automated AI-based image analysis for quantification and prediction of interstitial lung disease in systemic sclerosis patients
Published 2025-01-01“…Conclusion AI-based automatic quantification of lesions from chest-CT images in SSc-ILD is correlated with physiological parameters and can help in disease evaluation. …”
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6707
Diagnostics and treatment of exocrine pancreatic insufficiency: clinical guidelines of the Russian gastroenterological Association
Published 2018-08-01“…This state can develop primarily, due to various pancreatic diseases (chronic pancreatitis, pancreatic cancer, cystic fibrosis), and secondarily, due to impaired stimulation of pancreatic secretion or non-physiological conditions for activity of digestive enzymes. …”
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6708
Risk factor clusters for non-communicable diseases in adolescents in Eastern Cape, South Africa
Published 2025-01-01“…Methods: A stratified random sample of 266 adolescents (aged 12 years–18 years) was assessed for anthropometric, physiological, and perceived stress measures. Data included body mass index (BMI), blood pressure (BP), cholesterol, glucose levels, and perceived stress (via the Perceived Stress Scale). …”
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6709
The influence of anthropometric characteristics on swimming speed in adolescent swimmers
Published 2023-12-01“…Swimming speed depends on anthropometric characteristics, biomechanics factors, physical fitness, physiological components, and genetics. Therefore, this study aimed to identify which anthropometric characteristics influence swimming speed in adolescent competitive swimmers. …”
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6710
A review of hyperspectral image analysis techniques for plant disease detection and identif ication
Published 2022-04-01“…Hyperspectral analysis is a new subject that combines optical spectroscopy and image analysis methods, which make it possible to simultaneously evaluate both physiological and morphological parameters. The review describes the main steps of the hyperspectral data analysis process: image acquisition and preprocessing; data extraction and processing; modeling and analysis of data. …”
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6711
Induced resistance to the greenbug aphid Schizaphis graminum Rond. in species of the genus Triticum
Published 2019-11-01“….– infested with S. graminum greenbugs by physiological, biochemical, and molecular methods. Analysis of antibiosis and endurance showed that T. timopheevii k-58666 and T. monococcum k-39471 were resistant to S. graminum, the latter accession being the most enduring. …”
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6712
Role of cumulative biological risk in mediating socioeconomic disparities in cognitive function in the elderly: a mediation analysis
Published 2020-09-01“…Further efforts are required to elucidate the exact physiological pathways and mechanisms through which SES impacts cognitive function in late life.…”
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6713
Exploring trust in religious leaders and institutions as a mechanism for improving retention in child malnutrition interventions in the Philippines: a retrospective cohort study
Published 2020-09-01“…Objectives In the context of persistent child malnutrition in the Philippines, the objective of this study was to examine how different dimensions of trust affected programme retention and physiological outcomes when a faith-based organisation (FBO) addressed moderate and severe acute malnutrition among children from households experiencing extreme poverty.Setting We retrospectively analysed survey data collected by International Care Ministries (ICM) in 2012–2013 across 150 communities in eight provinces (Negros Oriental, Negros Occidental, Bohol, Palawan, Sarangani, South Cotabato, Sultan Kudarat and Zamboanga del Norte) of the Philippines.Study participants Caregivers of 1192 children experiencing moderate acute malnutrition and severe acute malnutrition between the ages of 6 and 60 months.Intervention A 16-week child malnutrition treatment programme called Malnourished Child Outreach offered by ICM in partnership with local religious leaders and institutions.Primary and secondary outcome measures Programme dropout and weight-for-height z-score (WHZ) at the end of the programme for enrolled children were the two outcomes of interest. …”
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6714
Comparative gametogenesis and genomic signatures associated with pollen sterility in the seedless mutant of grapevine
Published 2025-02-01“…RNAseq and genome sequencing data collectively indicate parthenocarpic seedless phenotype due to aberrant developmental and physiological processes involved in pollen formation, maturation and germination in the seedless mutant of ARI 516. …”
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6715
Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel
Published 2024-12-01“…<b>Background/Objectives:</b> Transient Receptor Potential Melastatin 8 (TRPM8) is a non-selective, Ca<sup>2+</sup>-permeable cation channel involved in thermoregulation and other physiological processes, such as basal tear secretion, cell differentiation, and insulin homeostasis. …”
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6716
Alendronate partially rescues the periodontal defects in OIM mouse model of osteogenesis imperfecta
Published 2025-01-01“…Periodontal ligament (PDL)-alveolar bone and PDL-cementum entheses’ roles under OI conditions during physiological loading and orthodontic forces remain largely unknown. …”
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6717
Genetics and pathophysiology of low-renin arterial hypertension
Published 2019-01-01“…The study of genetic and physiological mechanisms of various forms of low-renin arterial hypertension provides a good example of how penetration into the intimate mechanisms of the blood pressure regulation in each personal case makes it possible to identify some specifc syndromes and establish its fnal causes. …”
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6718
Sex differences in the expression of lipid oxidation and glucose uptake genes in muscles of fasted mice
Published 2019-02-01“…However, there is still little information on sex differences in muscle and FGF21 physiological response to fasting. Our aim was to find out whether there were sex differences in hormonal regulation and the expression of genes controlling glucose and lipid metabolism in skeletal muscles in response to fasting. …”
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6719
A new perspective on cardiovascular function and dysfunction during endurance exercise: identifying the primary cause of cardiovascular risk
Published 2024-04-01“…Additionally, we aim to identify the primary factors contributing to cardiovascular risk during strenuous prolonged exercise by highlighting recent progress in this area, which may shed light on previously unexplained physiological responses. To ascertain the effect of endurance exercise on cardiovascular function and dysfunction, a narrative review of the literature was undertaken using PubMed, ScienceDirect, Medline, Google Scholar, and Scopus. …”
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6720
Influence of lemongrass and oregano essential oils and their combination on in vitro ruminal fermentation and greenhouse gas emissions in total mixed ration for dairy cows
Published 2025-12-01“…LEO reduced pH (−0.6%, p=0.004), while OEO increased oxidation capacity (+4.2%, p=0.004), but both parameters remained within physiological ranges. Canonical discriminant analysis confirmed distinct EOs effects, highlighting their potential as natural additives for improving ruminal fermentation and mitigating ruminant environmental footprint.…”
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