Transforaminal lumbar interbody fusion (TLIF) surgery: A finite element analysis of open and minimally invasive approach on L4-L5 segment by Kishore Pradeep, Bidyut Pal, Kaushik Mukherjee, Gautam M. Shetty

“…The models were analyzed using an axial compressive load (500 N) and physiological movements like flexion, extension, and lateral bending with a combined load and moment (150 N and 10 Nm). …”
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Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

“…Abstract Pediatric mild traumatic brain injury (pmTBI) affects millions of youth annually but underlying pathophysiology and time for physiological recovery remains unknown. Non-fasting plasma samples were obtained in 59 pmTBI (28 females; age 14.9 ± 2.7) at approximately 7 days and 4 months post-injury and in 41 matched healthy controls (HC: 20 females; age 14.3 ± 2.8). …”
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Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID by David M. Smadja, David M. Smadja, M. Marc Abreu, M. Marc Abreu

“…Despite the absence of robust clinical trials, the therapeutic implications of WBH extend to immune modulation and the restoration of disrupted physiological pathways. However, the dual nature of hyperthermia's effects—balancing pro-inflammatory and anti-inflammatory responses—emphasizes the need for dose-controlled applications and stringent patient monitoring to minimize risks in vulnerable populations. …”
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The different response of PM2.5 stimulated nasal epithelial spheroids in control, asthma and COPD groups by Paulina Misiukiewicz-Stępień, Elwira Zajusz-Zubek, Katarzyna Górska, Rafał Krenke, Magdalena Paplińska-Goryca

“…The impairment of airway epithelium in asthma and COPD changes their response to toxic environmental stimuli. This physiological dysfunction might be associated with diseases exacerbation of obstructive lung diseases.…”
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Multi-Sensor-Fusion Approach for a Data-Science-Oriented Preventive Health Management System: Concept and Development of a Decentralized Data Collection Approach for Heterogeneous... by Sebastian Neubert, André Geißler, Thomas Roddelkopf, Regina Stoll, Karl-Heinz Sandmann, Julius Neumann, Kerstin Thurow

“…This requires convenient measurement solutions including physiological, psychological, physical, and sometimes emotional parameters. …”
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A pilot study on the effects of olfactory stimulation with white musk aromatic oil on psychophysiological activity: a crossover study by Fadilla Zennifa, Taisuke Nakashima, Yanli Xu, Saki Koshio, Erika Tomimatsu, Akiko Isa, Katsuya Satake, Fumi Kishida, Kuniyoshi Shimizu

“…To understand the changes in the participants’ impressions and mood states, POMS 2 (Profile of Mood States 2nd Edition) and VAS (Visual analogue scale) were performed in addition to physiological evaluation by using EEG (electroencephalogram), ECG (electrocardiogram) and salivary amylase measurements. …”
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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…In healthy tissues, binding to EpCAM and CD3 is greatly reduced by a novel, dual CAB selection, where each binding domain is independently blocked by the presence of physiological chemicals known as Protein-associated Chemical Switches (PaCS). …”
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Nitrogen Efficiency and Nutrient Absorption by a Sorghum-Oats Forage Succession by Rasiel Restelatto, Paulo Sergio Pavinato, Laércio Ricardo Sartor, Suelen Maria Einsfeld, Fernanda Paula Baldicera

“…The values of N recovery, efficiency, and N-use physiological efficiency were higher under lower N rates for both crops. …”
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The effect of space flight on genes expression in brain by A. S. Tsybko, T. V. Ilchibaeva, N. K. Popova

“…Many serious adverse physiological changes occur during spaceflight, primarily due to microgravity. …”
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Differences in gene expression between high and low tolerance rainbow trout (Oncorhynchus mykiss) to acute thermal stress. by Leah A Turner, Anne A Easton, Moira M Ferguson, Roy G Danzmann

“…We assessed the molecular and physiological processes that differentiate between rainbow trout (Oncorhynchus mykiss) with high and low tolerance to acute thermal stress. …”
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Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells by Fumiaki Makiyama, Shiori Kawase, Aoi William Omi, Yusuke Tanikawa, Taishi Kotani, Teruki Shirayama, Naoyuki Nishimura, Taiga Kurihara, Naoto Saito, Jun Takahashi, Takeshi Uemura

“…These results suggest the physiological significance of LPEs in bone formation and indicate that different LPE species and their receptors play distinctive roles in this process.…”
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Broad Diversity of Fungi in Hospital Water by Máira Gazzola Arroyo, Adriano Menis Ferreira, Oleci Pereira Frota, Natalia Seron Brizzotti-Mazuchi, Jacqueline Tanury Macruz Peresi, Marcelo Alessandro Rigotti, Carlos Eduardo Macedo, Alvaro Francisco Lopes de Sousa, Denise de Andrade, Margarete Teresa Gottardo de Almeida

“…Fungi were identified according to established methods based on macroscopic and microscopic characteristics (filamentous) and physiological tests (yeasts). Free chlorine residual content was measured at the time of sample collection. …”
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Study on Hematological and Biochemical Index of Blood and Vitreous Humor in the Celestial-Eye Goldfish by Rongni Li, Yansheng Sun, Xin Zhang, Wentong Li

“…After exploring the optimal method for collecting blood and ocular fluid, blood and vitreous humor samples were drawn from healthy CE, and an automatic hematology analyzer was used to measure 17 physiological indicators in the blood and vitreous humor. …”
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Development of an mPBPK machine learning framework for early target pharmacology assessment of biotherapeutics by Krutika Patidar, Nikhil Pillai, Saroj Dhakal, Lindsay B. Avery, Panteleimon D. Mavroudis

“…In the present work, we propose a machine learning-based target pharmacology assessment framework that utilizes minimal physiologically based pharmacokinetic (mPBPK) modeling and machine learning (ML) to infer optimal physicochemical properties of antibodies and their targets. …”
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Efficiency of Bacillus pseudomycoides RAY21 and Bacillus subtilis CYA27 Endospore Formulation on Biochar and Oil Spill Dispersant by Rifki Rahmatullah, Saiful Anwar, Mohamad Yani, Maulidi Firlandiana

“…This strain exhibited Gram-positive characteristics, formed endospores, and demonstrated potential on various media such as Pikovskaya, Alexandrov, and N-Free Mannitol. The physiological characterization indicated optimal growth in a pH range of 6-8, salinity up to 3.5%, and thermophilic properties. …”
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Research status of care experience and needs of family caregivers on gastrointestinal cancer patients (消化道肿瘤患者家庭照护者照护体验及需求研究现状) by SU Hongxia (苏红霞), YAN Wanhua (颜琬华)

“…The care experience of family caregivers of patients with gastrointestinal cancer mainly included three aspects: overloaded psychological load, decreased physiological function and limited social function; the needs of caregivers were mainly concentrated in the thirst for knowledge and skills in the care of patients with digestive tract cancer and the need for emotional and social support. …”
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A Mechanistic Study on the Non-genotoxic Carcinogenicity of the Food Contaminant Semicarbazide by Daniel P. Fitzpatrick

“…It is the hypothesis of the present study that the >2-fold increase in free radical concentration and upregulation of protein kinase C from the 0.01mM treatment of semicarbazide has the capacity to alter physiological signalling mechanisms into a sub- pathophysiological state. …”
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Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing by Xinyi Feng, Yu Zhang, Jun Feng, Zhongjun Li, Zhi Zhang, Lin Zhu, Ruoyu Zhou, Haibo Wang, Xiaojun Dai, Yanqing Liu

“…This deepens our understanding of the physiological and pathological mechanisms of advanced gastric cancer and helps to improve the diagnosis and treatment of advanced gastric cancer.…”
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Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges by Weigao Zhang, Hu Liu, Danyang Zhang, Yuguo Yi, Liang Tao, Yunfeng Zhu, Shuxian Huang, Xunan Zhao, Qianchao Shao, Peiqi Li, Yiwen Weng, Wei Lu, Jianfa Zhang, Haibing Zhang, Yuxin Chen, Dan Weng

“…Despite being a common physiological stressor that typically does not induce liver inflammation, short-term fasting triggered hepatic inflammation and compensatory proliferation in hepatocyte-specific RIPK1-deficient (Ripk1-hepKO) mice. …”
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PIWI proteins and piRNAs: key regulators of stem cell biology by Fernando Claro-Linares, Patricia Rojas-Ríos

“…Beyond their canonical roles, emerging evidence reveal their broader significance in maintaining stem cell properties and organismal health under physiological and pathological conditions.…”
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