PARylation of HMGA1 desensitizes esophageal squamous cell carcinoma to olaparib by Xin‐Yuan Lei, Kai‐Yue He, Qiu‐Tong Li, Lei Zhang, Dan‐Hui Wu, Jing‐Yu Yang, Jin‐Rong Guo, Meng‐Jie Liu, Zi‐Long Zhao, Jun‐Qi Li, Huai Liu, Yuan Zhao, Yu‐Jia Li, Qian‐Hui Sun, Chen‐Guang Wu, Yun‐Fan Wang, Geng‐Sheng Cao, Gang Wang, Yong‐Ping Jian, Zhi‐Xiang Xu

“…Abstract As a chromatin remodelling factor, high mobility group A1 (HMGA1) plays various roles in both physiological and pathological conditions. However, its role in DNA damage response and DNA damage‐based chemotherapy remains largely unexplored. …”
Get full text

Waiting Behavior and Arousal in Different Levels of Crowd Density: A Psychological Experiment with a “Tiny Box” by Mira Beermann, Anna Sieben

“…The results show that the correlation between crowd density and physiological arousal is more complex than expected. …”
Get full text

The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Connor J Plaisance, Lloyd F Ledet III, Nicholas J Slusher, Charles P Daniel, Zachary Lee, Bradley Dorius, Sonnah Barrie, Tomasina Q Parker-Actlis, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

“…Their original discovery is part of the beginning of what would become the search into the main mechanistic source of addiction, and how exactly it works at a cellular, physiological, and psychological level. The dopaminergic pathways of our brains are well-studied. …”
Get full text

Detection of Viable but Nonculturable E. coli Induced by Low-Level Antimicrobials Using AI-Enabled Hyperspectral Microscopy by MeiLi Papa, Aarham Wasit, Justin Pecora, Teresa M. Bergholz, Jiyoon Yi

“…The objectives were to (i) induce the VBNC state in Escherichia coli K-12 by exposure to selected antimicrobial stressors, (ii) obtain HMI data capturing physiological changes in VBNC cells, and (iii) automate the classification of normal and VBNC cells using deep learning image classification. …”
Get full text

The Effect of Culture Techniques of Hypoxic Stem Cell Secretome on The Number of Growth Factor TGF-β, BMP-2, VEGF by Mouli Edward, Ferdiansyah Mahyudin, Dionysius Bramta Putra Manyakori

“…Signaling molecules function in an orderly manner and are greatly influenced by the physiological environment. Stem cell culture techniques with hypoxic conditions can produce growth factors similar to those found in fracture conditions. …”
Get full text

Moving beyond the physical: Exploring the holistic benefits of a therapy-based physical activity program for individuals with Parkinson’s disease by Kimberly S. Fasczewski, Nolasco R. Stevens, Hannah S. Michels, Jennifer S. Howard

“…Furthermore, the benefits of therapeutic PA participation may extend beyond physiological outcomes by positively influencing social and psychological well-being, thus increasing the overall quality of life (QoL). …”
Get full text

“Pseudomonas fluorescens” as an Antagonist to Control Okra Root Rotting Fungi Disease in Plants by Harsha Sharma, Mohd Anul Haq, Ashok Kumar Koshariya, Anil Kumar, Sandeep Rout, Karthikeyan Kaliyaperumal

“…In this research work, five isolates have been chosen for further research based on their morphological, biochemical, and physiological characteristics. All five isolates have been identified as Pseudomonas fluorescens from Bergey’s Manual for the determination of bacteriology. …”
Get full text

Improving quality and outcomes of extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest: the Phoenix ECPR project by Michael Taylor, Vasileios Panoulas, Jill Smith, Alex Rosenberg, Mark Mason, Ian McGovern, Majid Akhtar, Sachin Mehta, Waqas Akhtar, Anthony McKay, Sumesh Thiruthalil, Orinta Kviatkovske, Donna Hall, Eftychia Galiatsou, Sofia Pinto, Maria Comanici, Emanuele Gerlando, Timothy Pitt, Joe Hughes, Olaf Maunz, Elia Keating, Julia Gangata, Eleanor Ross, Sophie Avetoom, Jane Durrant, Ciara Collins, Anand Jothidasan, Maria Monteagudo-Vela, Jerry Mitchell, Hatem Soliman Aboumarie, Caroline Bullen, Sundeep Kaul, Clara Hernandez Caballero, Ana Hurtado, Nick Lees

“…A new structured system including a systematic screening process, strict exclusion criteria, assessment of resuscitation adequacy through physiological stop criteria, drilled and standardised cannulation process, post-resuscitation care and neuroprognostication was rolled out on 1 April 2023. …”
Get full text

Potential of a Remotely Piloted Aircraft System with Multispectral and Thermal Sensors to Monitor Vineyard Characteristics for Precision Viticulture by Leeko Lee, Andrew Reynolds, Briann Dorin, Adam Shemrock

“…Grapevines are subjected to many physiological and environmental stresses that influence their vegetative and reproductive growth. …”
Get full text

GREEK «ΦΥΣΙΣ» AS THE BASIS OF GENDER STEREOTYPES by S. V. Storozhuk, I. M. Goyan

“…So when nature is seen in physiological or empirical sense, it establishes a pattern of gender inequality. …”
Get full text

Cats and dogs cross the line: domestic breeds follow Rensch’s rule, their wild relatives do not by C. J. Bidau, P. A. MartÍnez

“…The domestication syndrome already recognized by Darwin shows that domesticated species acquire a number of novel morphological, physiological and behavioral characteristics not present in their wild ancestors. …”
Get full text

Effect of Muscle Fatigue on Surface Electromyography-Based Hand Grasp Force Estimation by Jinfeng Wang, Muye Pang, Peixuan Yu, Biwei Tang, Kui Xiang, Zhaojie Ju

“…Surface electromyography- (sEMG-) based hand grasp force estimation plays an important role with a promising accuracy in a laboratory environment, yet hardly clinically applicable because of physiological changes and other factors. One of the critical factors is the muscle fatigue concomitant with daily activities which degrades the accuracy and reliability of force estimation from sEMG signals. …”
Get full text

Cut-off values of one-minute sit-to-stand test for determining physical performance in mild-post-COVID-19 individuals by Arunrat Srithawong, Puttipong Poncumhak, Tichanon Promsrisuk, Patchareeya Amput

“… # Conclusion A cutoff of less than 29 repetitions on the 1STST indicates functional impairment in mild post-COVID-19 cases, as it induces greater physiological stress than the 6MWT and correlates with muscle strength, making it crucial for rehabilitation assessment.…”
Get full text

Psychological determinants of performance in women's football: a systematic review on resilience, anxiety, motivation and cohesion by Javier Ventaja-Cruz, Jesús Manuel Cuevas Rincón, Virginia Tejada-Medina, Ricardo Martín-Moya

“…Results: anxiety is explored in five studies, highlighting its physiological and psychological effects on performance and its predictors in elite athletes; resilience is examined in three studies, focusing on how young female athletes adapt to adversity to enhance performance and life skills; motivation is the subject of six studies, emphasizing intrinsic and extrinsic factors driving engagement, performance, and social influences in sports; and team cohesion is analyzed in two studies, illustrating its role in fostering better performance perceptions and group dynamics. …”
Get full text

Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses by Yanyan He, Guangzu Du, Guang Wang, Huiming Guan, Shusheng Zhu, Bin Chen, Xiahong He, Youyong Zhu

“…Abstract Background GC16 is a novel pesticide with acaricidal properties against the spider mite Tetranychus pueraricola (Ehara & Gotoh). Its physiological mechanisms have been described previously, but its molecular mechanisms of action remain unclear. …”
Get full text

Dietary Chicory Inulin-Rich Meal Exerts Greater Healing Effects than Fructooligosaccharide Preparation in Rats with Trinitrobenzenesulfonic Acid-Induced Necrotic Colitis by Bartosz Fotschki, Adam Jurgoński, Joanna Fotschki, Michał Majewski, Katarzyna Ognik, Jerzy Juśkiewicz

“…Both chicory preparations beneficially regulated physiological parameters in the lower part of the rat intestinal tract after TNBS-induced colitis, however the dietary treatment with chicory meal showed stronger reduction of mucosal disturbances caused by colitis. …”
Get full text

Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells by Tackla S. Winston, Kantaphon Suddhapas, Chenyan Wang, Rafael Ramos, Pranav Soman, Zhen Ma

“…Combination of stem cell technology and 3D biofabrication approaches provides physiological similarity to in vivo tissues and the capability of repairing and regenerating damaged human tissues. …”
Get full text

Sustainable Nutritional Strategies for Gut Health in Weaned Pigs: The Role of Reduced Dietary Crude Protein, Organic Acids and Butyrate Production by Kathryn Ruth Connolly, Torres Sweeney, John V. O’Doherty

“…Weaning in piglets presents significant physiological and immunological challenges, including gut dysbiosis and increased susceptibility to post-weaning diarrhoea (PWD). …”
Get full text

Determination of the copy numbers of type A porcine endogenous retroviruses in domestic pigs and wild boars by R. B. Aitnazarov, N. S. Yudin, R. S. Kiril’chuk, N. N. Kochnev, S. P. Knyazev, M. I. Voevoda

“…With regard to economic and ethical criteria and to the anatomical and physiological similarity to humans, the pig is the best source of xenografts. …”
Get full text

Small open reading frames (sORFs): Driving big improvements in plant development and quality by Kui Dong, Chaofan Shan, Dongyu Wen, Zifan Cui, Jun Cao

“…The impact of sORFs extends well beyond stress resistance and they are also implicated in the developmental and physiological functions of plants. sORFs play a crucial role in determing the overall morphological architecture of plants, governing morphological changes throughout the plant life cycle, and are instrumental in regulating metabolite accumulation, which influences plant quality. …”
Get full text