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5861
Species-Related Differences in the Proteome of Rat and Human Pancreatic Beta Cells
Published 2015-01-01“…Besides conferring lower susceptibility to oxidative stress to human cells PRDX3 might also play a role in physiological redox regulation as, in rat, its expression was restricted to a beta cell subset with higher metabolic glucose responsiveness. …”
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5862
Enhancement of postharvest performance in Lilium tigrinum Ker Gawl flowers with Salicylic acid: a signalling molecule and a growth regulator
Published 2025-02-01“…These enhancements in physiological and biochemical stability can significantly enhance the economic viability of the floral industry by extending the postharvest longevity and maintaining the aesthetic integrity of cut flowers, thereby addressing the increasing global demand for superior-quality floral commodities. …”
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5863
Measuring Brain Tumor Growth: Combined Bioluminescence Imaging–Magnetic Resonance Imaging Strategy
Published 2009-09-01“…Magnetic resonance imaging (MRI) offers tumor localization, volumetric measurement, and the potential for advanced physiologic imaging but is less well suited to high-throughput studies and has limited capacity to assess early tumor growth. …”
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5864
The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells
Published 2015-01-01“…Together, these results add to a growing body of data suggesting that MMPs are effectors of hippocampal neuroplasticity in the adult CNS and that the MMP-1/PAR-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.…”
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5865
Reduced Expression of Voltage-Gated Sodium Channel Beta 2 Restores Neuronal Injury and Improves Cognitive Dysfunction Induced by Aβ1-42
Published 2022-01-01“…Voltage-gated sodium channel beta 2 (Nav2.2 or Navβ2, coded by SCN2B mRNA), a gene involved in maintaining normal physiological functions of the prefrontal cortex and hippocampus, might be associated with prefrontal cortex aging and memory decline. …”
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5866
Antimicrobial activity of Lactobacillus spp. isolated from fermented foods and their inhibitory effect against foodborne pathogens
Published 2025-01-01“…They were then identified by morphological, physiological and biochemical characteristics and confirmed by 16S rRNA gene sequencing. …”
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5867
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway
Published 2017-01-01“…Subsequently, ANGPTL4 has been shown to be involved in several nonmetabolic and metabolic conditions, both physiological and pathological, including angiogenesis and vascular permeability, cell differentiation, tumorigenesis, glucose homoeostasis, lipid metabolism, energy homeostasis, wound healing, inflammation, and redox regulation. …”
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5868
Generation of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination
Published 2025-01-01“…Rodent melanoma models have provided valuable insights into melanoma pathology; however, they often lack applicability to humans owing to genetic, anatomical, physiological, and metabolic differences. Herein, we developed a transgenic porcine melanoma model that closely resembles humans via somatic cell nuclear transfer (SCNT). …”
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5869
Fear extinction retention in children, adolescents, and adults
Published 2025-01-01“…In contrast to findings in rodents, fear conditioning in humans may elicit similar physiological responses and recruit similar neural networks from childhood to adulthood.…”
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5870
Tumor hypoxia evidences the differential regulation of Mdm2-p53 axis by PTEN in tumor derived vs. normal endothelial cells
Published 2024-12-01“…Abstract Hypoxia, a condition of oxygen tension lower than physiological level, plays a crucial role in shaping the tumor microenvironment and modulates distinct cell populations activity. …”
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5871
Improving gut microbiome through diet rich in dietary fibre and polyphenols: The case for orange peels
Published 2025-03-01“…The gut microbiota is crucial for various physiological functions, such as nutrient absorption, immune system enhancement, gut structural integrity, and detoxifying harmful substances. …”
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5872
A qualitative study on the real experience of discharging patients with urinary catheter placement after radical prostatectomy
Published 2025-01-01“…Data were collected through in-depth interviews and analyzed using NVivo 12.0 software and the Colaizzi 7-step analysis method for qualitative research.Results There were 3 themes and 8 sub-themes summarized from the interviews, including physiological discomfort and daily life challenges (limited daily activities, disrupted sleep, and challenges with clothing and personal hygiene), psychological stress and social difficulties (social stigma, social avoidance), social support and rehabilitation guidance (needs for family daily care support, needs for love and respect, rehabilitation guidance needs).Conclusion Patients undergoing radical prostatectomy with indwelling urinary catheters face complex lifestyle challenges after discharge. …”
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5873
Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature
Published 2015-01-01“…Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. …”
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5874
Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics
Published 2025-02-01“…These EVs have been shown to significantly influence the regulation of various physiological activities of cells in the joint cavity. …”
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5875
Transsulfuration pathway activation attenuates oxidative stress and ferroptosis in sickle primary erythroblasts and transgenic mice
Published 2025-01-01“…A vital contribution of the TSS pathway in sustaining cysteine levels is detected only under hemin exposure or physiological but not supraphysiological cystine supplement. …”
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5876
Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Published 2014-01-01“…Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer. …”
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5877
The impact of Ca2+ on the protective mechanisms of the photosystem under drought stress
Published 2025-12-01“…External calcium ions (Ca2+) play a crucial role in mitigating drought stress in plants, as revealed through physiological and transcriptomic analyses using tobacco (Nicotiana tabacum L) as a model system. …”
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5878
Nutritional and medicinal characteristics of Chinese giant salamander (Andrias davidianus) for applications in healthcare industry by artificial cultivation: A review
Published 2018-03-01“…The mucus, skin, meat and bone of CGS contain many different bioactive substances thereby having various medicinal activities including anti-aging, anti-fatigue, anti-tumor, therapy of burn and anti-infection and other physiological functions. This paper will further discuss the potential applications of the artificially cultivated CGS in healthcare industry and prospects of future technological development. …”
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5879
VARIETAL ASSESSMENT, HERITABILITY AND CORRELATION ANALYSIS OF ADAPTATION- AND PRODUCTION-RELATED TRAITS IN BREAD WHEAT LANDRACES OF THE ALGERIAN SAHARA OASES
Published 2024-12-01“…It evaluated their morphological, agronomical, physiological and phenological performance, and their related estimates of genetic variability and heritability under semi-arid conditions during the 2020/2021 growing season. …”
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5880
Neural Mass Modeling in the Cortical Motor Area and the Mechanism of Alpha Rhythm Changes
Published 2024-12-01“…Investigating the physiological mechanisms in the motor cortex during rehabilitation exercises is crucial for assessing stroke patients’ progress. …”
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