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5161
The control effect and induced disease resistance mechanism of Bacillus tequilensis on wheat powdery mildew
Published 2025-02-01“…The effects on wheat defence enzymes were clarified via physiological and biochemical techniques. The results revealed that B. tequilensis controlled WPM at an effective concentration of 1 × 107 cfu/mL or higher. …”
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5162
Urine metabolic profile in rats with arterial hypertension of different genesis
Published 2024-05-01“…Metabolomics is one of the promising methods for personalized medicine, as it provides a comprehensive understanding of the physiological processes occurring in the body. The metabolome is a set of low-molecular substances available for detection in a sample and representing intermediate and final products of cell metabolism. …”
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5163
Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts
Published 2020-01-01“…Two cholesterol secosterol aldehydes, namely, 3β-hydroxy-5-oxo-5,6-secocholestan-6-al (secosterol A) and its aldolization product 3β-hydroxy-5β-hydroxy-B-norcholestane-6β-carboxyaldehyde (secosterol B), are highly bioactive compounds which have been detected in human tissues and potentially contribute to the development of physiological dysfunctions such as atherosclerosis, Alzheimer’s disease, diabetes, and cancer. …”
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5164
Characterization of subcutaneous and visceral de-differentiated fat cells
Published 2025-03-01“…Moreover, whether de-differentiation of mature adipocytes from classical subcutaneous and visceral depots occurs under physiological conditions remains unknown. Methods: Here, we used in vitro ''ceiling culture'', single cell/nucleus RNA sequencing, epigenetic anaysis and genetic lineage tracing to address these unknowns. …”
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5165
Anthocyanin-Rich Blackcurrant Supplementation as a Nutraceutical Ergogenic Aid for Exercise Performance and Recovery: A Narrative Review
Published 2025-01-01“…Polyphenols have emerged as a promising area of research with application for sport and exercise nutrition owing to affecting physiologic mechanisms for exercise performance and recovery. …”
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5166
An evaluation of osseous regeneration capability of novel autogenous tooth graft along with orthobiologics for long bone segmental defects
Published 2025-01-01“…The therapeutic regimens were extensively appraised in terms of physiological vitals, hematology, serology, bone biomarkers, mechanical assessment, radiography and histomorphometric parameters. …”
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5167
Salinity affects the lipid metabolism and intestinal microbial composition of swimming crab Portunus trituberculatus
Published 2025-03-01“…This study investigated the hepatopancreatic index, hepatopancreatic lipid metabolism, physiological and biochemical indicators and gut microbiota of P. trituberculatus cultured at salinity 28 ‰, 25 ‰, 22 ‰ and 19 ‰ for 8 weeks. …”
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5168
Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure
Published 2021-01-01“…The administration of URB597 was able to reverse the depressive-like behavior generated in mice after the model. Likewise, other physiological responses associated with CUS were reduced in the treated group, among them, increase in the relative weight of the adrenal glands, increased oxidative stress, and decreased BDNF and number of neural precursors. …”
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5169
Psychological Status of Medical Staff in Obstetrics and Gynecology Hospitals during the Omicron Pandemic Outbreak in China
Published 2024-01-01“…Medical staff in China faced great challenges and psychological and physiological changes of varying degrees during the omicron epidemic outbreak. …”
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5170
Computational Study of the Phytochemical Constituents from Uncaria tomentosa Stem Bark against SARS-CoV-2 Omicron Spike Protein
Published 2022-01-01“…As results proanthocyanidin-C1 (-10.76 kcal/mol), quinovic acid-type 2 (-9.86 kcal/mol), and proanthocyanidin-B2 (-9.82 kcal/mol) were the constituents with the best binding free energy on the SARS-CoV-2 Omicron spike protein, and the best compound was stable during the dynamic simulation under physiological conditions. It is concluded that the anthocyanidin-based compounds determined in the stem bark ethanol extract could be responsible for the potential antiviral activity on SARS-CoV-2 Omicron variant, and the proanthocyanidin-C1 emerged as a powerful candidate to combat new variants.…”
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5171
<i>Macrostomum lignano</i> as a model to study the genetics and genomics of parasitic flatworms
Published 2021-03-01“…Parasitic flatworms have complex life cycles, are laborious and expensive in culturing, and have a range of anatomic and physiological adaptations that complicate the application of standard molecular-biological methods. …”
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5172
Time-Restricted Feeding Reinforces Gut Rhythmicity by Restoring Rhythms in Intestinal Metabolism in a Jetlag Mouse ModelSummary
Published 2025-01-01“…We investigated which physiological pathways in jejunal mucosa were disrupted during chronic jetlag and prevented during time-restricted feeding (TRF). …”
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5173
Data Mining Evidences Variabilities in Glucose and Lipid Metabolism among Fish Strains: A Case Study on Three Genotypes of Gibel Carp Fed by Different Carbohydrate Sources
Published 2023-01-01“…Spearman’s correlation analysis of the physiological responses indicated that plasma glucose had a significantly negative correlation with growth, feed utilization, glycogen storage, and plasma cholesterol level, and it was positively related to liver fat content in gibel carp. …”
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5174
Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice
Published 2025-02-01“…Background: Aging is a complex biological process that disrupts tissue structure and impairs physiological function, which contributes to the development of age-related diseases such as cardiovascular disorders. …”
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5175
Construction of complex three-dimensional vascularized liver tissue model in vitro based on a biphasic cell-laden embedding medium
Published 2025-01-01“…Constructing an in vitro vascularized liver tissue model that closely simulates the human liver is crucial for promoting cell proliferation, mimicking physiological heterogeneous structures, and recreating the cellular microenvironment. …”
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5176
Comparative transcriptome analysis reveals the key role of photosynthetic traits in the formation of differences in photothermal sensitivity in tobacco
Published 2025-01-01“…The aim was to comparatively analyze the changes in agronomic traits, biomass, and physiological indices of the varieties under different experimental conditions, as well as to conduct transcriptome analyses. …”
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5177
CIRBP Regulates Pancreatic Cancer Cell Ferroptosis and Growth by Directly Binding to p53
Published 2022-01-01“…CIRBP is a cold-induced protein that plays a key role in many physiological and pathological processes, but its role in pancreatic cancer is still unclear. …”
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5178
Development of a Novel Co-Amorphous Curcumin and L-Arginine (1:2): Structural Characterization, Biological Activity and Pharmacokinetics
Published 2024-12-01“…<b>Results</b>: CAC12 was 1000 times more soluble than curcumin, and it was stable for 1 month at 40 °C and 75% relative humidity or for 60 min in physiological medium at pH 4.5–6.8. Co-amorphous curcumin/L-arginine, but not curcumin + L-arginine, decreased carrageenan- or CFA-induced inflammation and nociception by decreasing IL-1α, IL-1β, IL-6, TNF-α, MCP-1 and CXCL1 cytokines. …”
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5179
Molecular genetic bases of seed resistance to oxidative stress during storage
Published 2020-08-01“…During storage seeds suffer physiological stress consequences, one of which is the accumulation of free radicals, primarily reactive oxygen species (ROS). …”
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5180
Preparation, Characterization, and Biotoxicity of Nanosized Doped ZnO Photocatalyst
Published 2014-01-01“…Sizes, dissolubility, and physiological functions of doping metals were the influencing factors on metal-doped nZnO biotoxicity to D. magna.…”
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