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4981
Comparative analysis of unicortical vs. subchondral locking screws in osteoporotic proximal humerus fractures
Published 2025-02-01“…Axial load to failure and cyclic physiologic abduction moments were applied in biomechanical testing. …”
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4982
A Multi-Year Study of Forchlorfenuron’s Effects on Physical Fruit Quality Parameters in <i>A. chinensis</i> var. <i>chinensis</i>
Published 2025-01-01“…Therefore, controlling field variables is essential to fully realize the benefits of CPPU and to avoid interference with the plant’s physiological responses.…”
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4983
Benefits of Gardenia jasminoides Ellis’s floral volatile components on human emotions and moods
Published 2025-02-01“…Additionally, the perception of gardenia odor by college students was found to be associated with various physiological and psychological indicators in the experiment. …”
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4984
In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction
Published 2025-02-01“…Pathogenic mutations in the CSTA gene can disrupt this interaction, potentially leading to physiological ailments. In this study, eight bioinformatics tools (SIFT, PolyPhen-2, PROVEAN, P-Mut, MutPred2, SNAP2, SNPs & GO, and PHD-SNP) were implemented to analyze non-synonymous SNPs from the dbSNP database. …”
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4985
Benefits of Kangaroo Mother Care for the “Larger” Low Birth Weight Infant (> 2000g)
Published 2025-01-01“…The 2022 WHO recommendations expanded KMC to infants up to 2500 g prompting this study to assess its impact particularly on ldquolargerrdquo LBW infants.Methodology This was an observational study carried out in a South Indian tertiary care hospital included infants 750-2500 g clinically stable for KMC. Physiological parameters were monitored during KMC and conventional care. …”
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4986
Cognitive Behavioral Treatment of Blood-Injection-Injury Phobia: A Case Report
Published 2018-12-01“…Unlike other specific phobias, physiological responses (e.g., fainting), called vasovagal syncope, are encountered in blood-injection-injury phobia. …”
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4987
Transforaminal lumbar interbody fusion (TLIF) surgery: A finite element analysis of open and minimally invasive approach on L4-L5 segment
Published 2025-01-01“…The models were analyzed using an axial compressive load (500 N) and physiological movements like flexion, extension, and lateral bending with a combined load and moment (150 N and 10 Nm). …”
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4988
Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury
Published 2025-02-01“…Abstract Pediatric mild traumatic brain injury (pmTBI) affects millions of youth annually but underlying pathophysiology and time for physiological recovery remains unknown. Non-fasting plasma samples were obtained in 59 pmTBI (28 females; age 14.9 ± 2.7) at approximately 7 days and 4 months post-injury and in 41 matched healthy controls (HC: 20 females; age 14.3 ± 2.8). …”
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4989
Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID
Published 2025-02-01“…Despite the absence of robust clinical trials, the therapeutic implications of WBH extend to immune modulation and the restoration of disrupted physiological pathways. However, the dual nature of hyperthermia's effects—balancing pro-inflammatory and anti-inflammatory responses—emphasizes the need for dose-controlled applications and stringent patient monitoring to minimize risks in vulnerable populations. …”
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4990
Multi-Sensor-Fusion Approach for a Data-Science-Oriented Preventive Health Management System: Concept and Development of a Decentralized Data Collection Approach for Heterogeneous...
Published 2019-01-01“…This requires convenient measurement solutions including physiological, psychological, physical, and sometimes emotional parameters. …”
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4991
A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy
Published 2024-12-01“…In healthy tissues, binding to EpCAM and CD3 is greatly reduced by a novel, dual CAB selection, where each binding domain is independently blocked by the presence of physiological chemicals known as Protein-associated Chemical Switches (PaCS). …”
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4992
Nitrogen Efficiency and Nutrient Absorption by a Sorghum-Oats Forage Succession
Published 2015-01-01“…The values of N recovery, efficiency, and N-use physiological efficiency were higher under lower N rates for both crops. …”
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4993
The effect of space flight on genes expression in brain
Published 2016-05-01“…Many serious adverse physiological changes occur during spaceflight, primarily due to microgravity. …”
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4994
Broad Diversity of Fungi in Hospital Water
Published 2020-01-01“…Fungi were identified according to established methods based on macroscopic and microscopic characteristics (filamentous) and physiological tests (yeasts). Free chlorine residual content was measured at the time of sample collection. …”
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4995
Study on Hematological and Biochemical Index of Blood and Vitreous Humor in the Celestial-Eye Goldfish
Published 2025-01-01“…After exploring the optimal method for collecting blood and ocular fluid, blood and vitreous humor samples were drawn from healthy CE, and an automatic hematology analyzer was used to measure 17 physiological indicators in the blood and vitreous humor. …”
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4996
Development of an mPBPK machine learning framework for early target pharmacology assessment of biotherapeutics
Published 2025-02-01“…In the present work, we propose a machine learning-based target pharmacology assessment framework that utilizes minimal physiologically based pharmacokinetic (mPBPK) modeling and machine learning (ML) to infer optimal physicochemical properties of antibodies and their targets. …”
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4997
A Mechanistic Study on the Non-genotoxic Carcinogenicity of the Food Contaminant Semicarbazide
Published 2020-10-01“…It is the hypothesis of the present study that the >2-fold increase in free radical concentration and upregulation of protein kinase C from the 0.01mM treatment of semicarbazide has the capacity to alter physiological signalling mechanisms into a sub- pathophysiological state. …”
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4998
Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing
Published 2025-01-01“…This deepens our understanding of the physiological and pathological mechanisms of advanced gastric cancer and helps to improve the diagnosis and treatment of advanced gastric cancer.…”
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4999
Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges
Published 2025-01-01“…Despite being a common physiological stressor that typically does not induce liver inflammation, short-term fasting triggered hepatic inflammation and compensatory proliferation in hepatocyte-specific RIPK1-deficient (Ripk1-hepKO) mice. …”
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5000
PIWI proteins and piRNAs: key regulators of stem cell biology
Published 2025-02-01“…Beyond their canonical roles, emerging evidence reveal their broader significance in maintaining stem cell properties and organismal health under physiological and pathological conditions.…”
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